TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T45593 Microtubule-associated protein tau D05TPI EPICATECHIN Phase 2 72276 C15H14O6 290.27 C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C=C3)O)O)O IC50 >= 200000 nM Non binder T45593 Microtubule-associated protein tau B0K7UO 4-[4-Bromo-5-(3,4-dihydroxyphenyl)thiophen-2-yl]benzene-1,2-diol Investigative 66548560 C16H11BrO4S 379.2 C1=CC(=C(C=C1C2=CC(=C(S2)C3=CC(=C(C=C3)O)O)Br)O)O IC50 = 211100 nM Non binder T45593 Microtubule-associated protein tau B1ERA8 2,5-Bis(3,4-dihydroxyphenyl)-1,3,4-thiadiazole Investigative 135409971 C14H10N2O4S 302.31 C1=CC(=C(C=C1C2=NN=C(S2)C3=CC(=C(C=C3)O)O)O)O IC50 = 290200 nM Non binder T45593 Microtubule-associated protein tau BAE38O 4-[5-(3,4-Dihydroxyphenyl)-1,3,4-oxadiazol-2-yl]benzene-1,2-diol Investigative 136265454 C14H10N2O5 286.24 C1=CC(=C(C=C1C2=NN=C(O2)C3=CC(=C(C=C3)O)O)O)O IC50 = 3941000 nM Non binder