TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T46185	Muscarinic acetylcholine receptor M2	B0LCK4	4-[4-(4-Hydroxy-4,4-diphenylbutyl)-4-methylpiperazin-4-ium-1-yl]-1,1-diphenylbutan-1-ol;iodide	Investigative	44448499	C37H45IN2O2	676.7	C[N+]1(CCN(CC1)CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O)CCCC(C4=CC=CC=C4)(C5=CC=CC=C5)O.[I-]	Ki = 437000000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	B12LNH	Trimethyl-[[(2S,6R)-6-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	44422698	C9H20INO2	301.17	C[C@@H]1COC[C@@H](O1)C[N+](C)(C)C.[I-]	EC50 = 64600000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	B19XTZ	4-[4-[1-(4-Hydroxy-4,4-diphenylbutyl)-1-methylpiperidin-1-ium-4-yl]-1-methylpiperidin-1-ium-1-yl]-1,1-diphenylbutan-1-ol;diiodide	Investigative	44448383	C44H58I2N2O2	900.8	C[N+]1(CCC(CC1)C2CC[N+](CC2)(C)CCCC(C3=CC=CC=C3)(C4=CC=CC=C4)O)CCCC(C5=CC=CC=C5)(C6=CC=CC=C6)O.[I-].[I-]	Ki = 2750000000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	B1KPY8	4-[4-(1,1-Dimethylpiperidin-1-ium-4-yl)-1-methylpiperidin-1-ium-1-yl]-1,1-diphenylbutan-1-ol;diiodide	Investigative	44448379	C29H44I2N2O	690.5	C[N+]1(CCC(CC1)C2CC[N+](CC2)(C)CCCC(C3=CC=CC=C3)(C4=CC=CC=C4)O)C.[I-].[I-]	Ki = 229000000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	B2TBK1	Trimethyl-[[(2R,6S)-6-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide	Investigative	24865894	C9H20INO2	301.17	C[C@H]1COC[C@H](O1)C[N+](C)(C)C.[I-]	EC50 = 26900000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	B2TJ5E	4-[2-[(4-Hydroxy-4,4-diphenylbutyl)-methylamino]ethyl-methylamino]-1,1-diphenylbutan-1-ol;dihydrochloride	Investigative	49797390	C36H46Cl2N2O2	609.7	CN(CCCC(C1=CC=CC=C1)(C2=CC=CC=C2)O)CCN(C)CCCC(C3=CC=CC=C3)(C4=CC=CC=C4)O.Cl.Cl	Ki = 4680000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	B47IWT	Ethyl 17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate	Investigative	4995951	C23H24N2O4	392.4	CCOC(=O)C1=C(NC2=C1C3=C(C=C2)OC4C5=C(CCN4C3)C=C(C=C5)OC)C	Ki = 912000000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	B4QG5Z	4-[4-[1-(4-Hydroxy-4,4-diphenylbutyl)piperidin-4-yl]piperidin-1-yl]-1,1-diphenylbutan-1-ol;dihydrochloride	Investigative	49797389	C42H54Cl2N2O2	689.8	C1CN(CCC1C2CCN(CC2)CCCC(C3=CC=CC=C3)(C4=CC=CC=C4)O)CCCC(C5=CC=CC=C5)(C6=CC=CC=C6)O.Cl.Cl	Ki = 1150000000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	B5DKA3	(4-Hydroxy-4,4-diphenylbutyl)-[3-[(4-hydroxy-4,4-diphenylbutyl)-dimethylazaniumyl]propyl]-dimethylazanium;diiodide	Investigative	44448418	C39H52I2N2O2	834.6	C[N+](C)(CCCC(C1=CC=CC=C1)(C2=CC=CC=C2)O)CCC[N+](C)(C)CCCC(C3=CC=CC=C3)(C4=CC=CC=C4)O.[I-].[I-]	Ki = 83200000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	B5HRN9	Trimethyl-[(6-methyl-1,4-dioxan-2-yl)methyl]azanium;iodide	Investigative	44422691	C9H20INO2	301.17	CC1COCC(O1)C[N+](C)(C)C.[I-]	EC50 = 1290000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	B8JN9T	1,1-Diphenyl-4-piperazin-1-ylbutan-1-ol;dihydrochloride	Investigative	49797395	C20H28Cl2N2O	383.4	C1CN(CCN1)CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O.Cl.Cl	Ki = 138000000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	B9C0OK	4-[3-[(4-Hydroxy-4,4-diphenylbutyl)-methylamino]propyl-methylamino]-1,1-diphenylbutan-1-ol;dihydrochloride	Investigative	49797388	C37H48Cl2N2O2	623.7	CN(CCCC(C1=CC=CC=C1)(C2=CC=CC=C2)O)CCCN(C)CCCC(C3=CC=CC=C3)(C4=CC=CC=C4)O.Cl.Cl	Ki = 182000000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	BCA76V	(4-Hydroxy-4,4-diphenylbutyl)-[2-[(4-hydroxy-4,4-diphenylbutyl)-dimethylazaniumyl]ethyl]-dimethylazanium;diiodide	Investigative	44448456	C38H50I2N2O2	820.6	C[N+](C)(CCCC(C1=CC=CC=C1)(C2=CC=CC=C2)O)CC[N+](C)(C)CCCC(C3=CC=CC=C3)(C4=CC=CC=C4)O.[I-].[I-]	Ki = 20900000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	BCAJ53	1,1-Diphenyl-4-(4-phenylpiperazin-1-yl)butan-1-ol;hydrochloride	Investigative	49797392	C26H31ClN2O	423	C1CN(CCN1CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O)C4=CC=CC=C4.Cl	Ki = 2190000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	BE7M1V	4-(4,4-Dimethylpiperazin-4-ium-1-yl)-1,1-diphenylbutan-1-ol;iodide	Investigative	44448537	C22H31IN2O	466.4	C[N+]1(CCN(CC1)CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O)C.[I-]	Ki = 42700000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	BEZJ94	4-(1-Methyl-4-phenylpiperazin-1-ium-1-yl)-1,1-diphenylbutan-1-ol;iodide	Investigative	44448495	C27H33IN2O	528.5	C[N+]1(CCN(CC1)C2=CC=CC=C2)CCCC(C3=CC=CC=C3)(C4=CC=CC=C4)O.[I-]	Ki = 38900000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	BM6Q1Z	Diphenidol hydrochloride	Investigative	66266	C21H28ClNO	345.9	C1CCN(CC1)CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O.Cl	Ki = 355000000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	BP2VC7	4-[4-(4-Hydroxy-4,4-diphenylbutyl)piperazin-1-yl]-1,1-diphenylbutan-1-ol;dihydrochloride	Investigative	49797391	C36H44Cl2N2O2	607.6	C1CN(CCN1CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O)CCCC(C4=CC=CC=C4)(C5=CC=CC=C5)O.Cl.Cl	Ki = 5620000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	BRC7N9	4-(4-Methylpiperazin-1-yl)-1,1-diphenylbutan-1-ol;dihydrochloride	Investigative	49797394	C21H30Cl2N2O	397.4	CN1CCN(CC1)CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O.Cl.Cl	Ki = 28200000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	BX84RC	4-(1-Methylpiperidin-1-ium-1-yl)-1,1-diphenylbutan-1-ol;iodide	Investigative	44448645	C22H30INO	451.4	C[N+]1(CCCCC1)CCCC(C2=CC=CC=C2)(C3=CC=CC=C3)O.[I-]	Ki = 3630000000000000 nM	Non binder
T46185	Muscarinic acetylcholine receptor M2	BZD1R6	4-[4-(1-Methylpiperidin-4-yl)piperidin-1-yl]-1,1-diphenylbutan-1-ol;dihydrochloride	Investigative	49797387	C27H40Cl2N2O	479.5	CN1CCC(CC1)C2CCN(CC2)CCCC(C3=CC=CC=C3)(C4=CC=CC=C4)O.Cl.Cl	Ki = 251000000000000 nM	Non binder