TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T48703	Toll-like receptor 8	D06CTE	Imiquimod	Approved	57469	C14H16N4	240.3	CC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N	EC50 > 270000 nM	Non binder
T48703	Toll-like receptor 8	B2B8HQ	4-Amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinoline-1-ethanol	Investigative	130714	C14H16N4O	256.3	CC(C)(CN1C=NC2=C1C3=CC=CC=C3N=C2N)O	EC50 > 270000 nM	Non binder
T48703	Toll-like receptor 8	BH2UM0	6-Amino-2-butoxy-9-(3-piperidin-4-ylpropyl)-7H-purin-8-one;hydrochloride	Investigative	118727489	C17H29ClN6O2	384.9	CCCCOC1=NC(=C2C(=N1)N(C(=O)N2)CCCC3CCNCC3)N.Cl	EC50 = 260000 nM	Non binder
T48703	Toll-like receptor 8	BK8LB2	Methyl 4-amino-1-(2-hydroxy-2-methylpropyl)imidazo[4,5-c]quinoline-7-carboxylate	Investigative	71292238	C16H18N4O3	314.34	CC(C)(CN1C=NC2=C1C3=C(C=C(C=C3)C(=O)OC)N=C2N)O	EC50 > 270000 nM	Non binder
T48703	Toll-like receptor 8	BX1W2D	6-Amino-2-butoxy-9-(2-piperidin-4-ylethyl)-7H-purin-8-one;hydrochloride	Investigative	118727488	C16H27ClN6O2	370.9	CCCCOC1=NC(=C2C(=N1)N(C(=O)N2)CCC3CCNCC3)N.Cl	EC50 = 231000 nM	Non binder