TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T49031	Proteasome beta-5	D0SH3I	Bortezomib	Approved	387447	C19H25BN4O4	384.2	B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O	IC50 = 512861384 nM	Non binder
T49031	Proteasome beta-5	B0QUS3	N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide	Investigative	46233206	C29H39BN4O4	518.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)C5=NC=CN=C5	IC50 = 524807460.3 nM	Non binder
T49031	Proteasome beta-5	B1MTB2	Tert-butyl N-[(2S)-4-methyl-1-oxo-1-[[(1R)-2-phenyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]amino]pentan-2-yl]carbamate	Investigative	127028491	C29H45BN2O5	512.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C	IC50 = 8317637.71 nM	Non binder
T49031	Proteasome beta-5	B32VPR	(1S)-N-[(2S)-1-[[(1R)-2-(4-Methylphenyl)-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]amino]-1-oxo-3-phenylpropan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053274	C39H47BN2O4	618.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=C(C=C4)C)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@H]6CCCC7=CC=CC=C67	IC50 = 147910838.8 nM	Non binder
T49031	Proteasome beta-5	B37AWE	N-[(2S)-1-[[(1R)-2-(4-Methylphenyl)-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide	Investigative	127053228	C33H39BN4O4	566.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=C(C=C4)C)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)C6=NC=CN=C6	IC50 = 208929613.1 nM	Non binder
T49031	Proteasome beta-5	B37TEH	(2S)-2-Acetamido-N-[(1R)-3-methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]-3-phenylpropanamide	Investigative	127030041	C26H39BN2O4	454.4	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)C	IC50 = 426579518.8 nM	Non binder
T49031	Proteasome beta-5	B5H9QT	(1R)-N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxo-3-phenylpropan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053269	C35H47BN2O4	570.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@@H]5CCCC6=CC=CC=C56	IC50 = 194984460 nM	Non binder
T49031	Proteasome beta-5	B68RJQ	Tert-butyl N-[(2S)-3-(4-hydroxyphenyl)-1-oxo-1-[[(1R)-2-phenyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]amino]propan-2-yl]carbamate	Investigative	127030044	C32H43BN2O6	562.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CC=C(C=C5)O)NC(=O)OC(C)(C)C	IC50 = 8709635.9 nM	Non binder
T49031	Proteasome beta-5	B6DOM7	(1S)-N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053280	C39H49BN2O4	620.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC5=CC=CC=C5C=C4)NC(=O)[C@H]6CCCC7=CC=CC=C67	IC50 = 162181009.7 nM	Non binder
T49031	Proteasome beta-5	B6GE1I	N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide	Investigative	127030638	C39H49BN2O4	620.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC5=CC=CC=C5C=C4)NC(=O)C6=CC=CC7=C6CCCC7	IC50 = 862978547.8 nM	Non binder
T49031	Proteasome beta-5	B75ISH	N-[(2S)-3-(1H-Indol-3-yl)-1-[[(1R)-3-methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxopropan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053300	C37H48BN3O4	609.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CNC5=CC=CC=C54)NC(=O)C6CCCC7=CC=CC=C67	IC50 = 275422870.3 nM	Non binder
T49031	Proteasome beta-5	B7FL4T	N-[(2S)-3-Methyl-1-[[(1R)-3-methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxobutan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053293	C31H47BN2O4	522.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)C4CCCC5=CC=CC=C45	IC50 = 25703957.83 nM	Non binder
T49031	Proteasome beta-5	B7JK1E	(2S)-2-Acetamido-N-[(1R)-2-(4-methylphenyl)-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]-3-phenylpropanamide	Investigative	127030042	C30H39BN2O4	502.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=C(C=C4)C)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)C	IC50 = 363078054.8 nM	Non binder
T49031	Proteasome beta-5	B8PG9S	N-[(2S)-4-Methyl-1-[[(1R)-3-methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxopentan-2-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide	Investigative	127030317	C32H49BN2O4	536.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C4=CC=CC5=C4CCCC5	IC50 = 868960429.3 nM	Non binder
T49031	Proteasome beta-5	B8ZIR4	N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]naphthalene-2-carboxamide	Investigative	127030637	C39H45BN2O4	616.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=CC5=CC=CC=C54)NC(=O)C6=CC7=CC=CC=C7C=C6	IC50 = 407380277.8 nM	Non binder
T49031	Proteasome beta-5	B9P7HR	(1S)-N-[(2S)-1-Oxo-3-phenyl-1-[[(1R)-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]pentyl]amino]propan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053272	C35H47BN2O4	570.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CCCC)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H]5CCCC6=CC=CC=C56	IC50 = 524807460.3 nM	Non binder
T49031	Proteasome beta-5	BA05XH	Benzyl N-[(2S)-1-[[(2S)-1-[[(1S)-1-cyano-3-methylbutyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate	Investigative	44410779	C26H40N4O4	472.6	CC(C)C[C@@H](C#N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1	Ki > 450000 nM	Non binder
T49031	Proteasome beta-5	BAKW60	(1S)-N-[(2S)-1-[[(1R)-2-(4-Fluorophenyl)-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]amino]-1-oxo-3-phenylpropan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053285	C38H44BFN2O4	622.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=C(C=C4)F)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@H]6CCCC7=CC=CC=C67	IC50 = 794328234.7 nM	Non binder
T49031	Proteasome beta-5	BD1BL4	N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	49799952	C39H49BN2O4	620.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=CC5=CC=CC=C54)NC(=O)C6CCCC7=CC=CC=C67	IC50 = 234422881.5 nM	Non binder
T49031	Proteasome beta-5	BDC52E	N-[(2S)-1-Oxo-3-phenyl-1-[[(1R)-2-phenyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]amino]propan-2-yl]-1,2,3,4-tetrahydronaphthalene-2-carboxamide	Investigative	127030315	C38H45BN2O4	604.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)C6CCC7=CC=CC=C7C6	IC50 = 295120922.7 nM	Non binder
T49031	Proteasome beta-5	BE5B1C	N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxo-3-phenylpropan-2-yl]-1,2,3,4-tetrahydronaphthalene-2-carboxamide	Investigative	127053301	C35H47BN2O4	570.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)C5CCC6=CC=CC=C6C5	IC50 = 691830970.9 nM	Non binder
T49031	Proteasome beta-5	BEAZ23	(2S)-2-Acetamido-3-phenyl-N-[(1R)-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]pentyl]propanamide	Investigative	127030040	C26H39BN2O4	454.4	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CCCC)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)C	IC50 = 117489755.5 nM	Non binder
T49031	Proteasome beta-5	BGB65X	(1S)-N-[(2S)-1-Oxo-3-phenyl-1-[[(1R)-2-phenyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]amino]propan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053273	C38H45BN2O4	604.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)[C@H]6CCCC7=CC=CC=C67	IC50 = 190546071.8 nM	Non binder
T49031	Proteasome beta-5	BH93ER	(1S)-N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxo-3-phenylpropan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053268	C35H47BN2O4	570.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H]5CCCC6=CC=CC=C56	IC50 = 893305483.7 nM	Non binder
T49031	Proteasome beta-5	BJ69MH	N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-3-naphthalen-1-yl-1-oxopropan-2-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide	Investigative	127030636	C39H49BN2O4	620.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=CC5=CC=CC=C54)NC(=O)C6=CC=CC7=C6CCCC7	IC50 = 741310241.3 nM	Non binder
T49031	Proteasome beta-5	BJC3G4	Benzyl N-[(2S)-3-(1H-indol-3-yl)-1-[[(1R)-2-(4-methylphenyl)-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]amino]-1-oxopropan-2-yl]carbamate	Investigative	127028815	C38H44BN3O5	633.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=C(C=C4)C)NC(=O)[C@H](CC5=CNC6=CC=CC=C65)NC(=O)OCC7=CC=CC=C7	IC50 = 301995172 nM	Non binder
T49031	Proteasome beta-5	BJPE85	N-[(2S)-3-Methyl-1-[[(1R)-3-methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxopentan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053295	C32H49BN2O4	536.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](C(C)CC)NC(=O)C4CCCC5=CC=CC=C45	IC50 = 57543993.73 nM	Non binder
T49031	Proteasome beta-5	BL2Q0D	[(1R)-2-(4-Fluorophenyl)-1-[[(2S)-3-phenyl-2-(pyrazine-2-carbonylamino)propanoyl]amino]ethyl]boronic acid	Investigative	44190246	C22H22BFN4O4	436.2	B([C@H](CC1=CC=C(C=C1)F)NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)C3=NC=CN=C3)(O)O	IC50 = 229086765.3 nM	Non binder
T49031	Proteasome beta-5	BLF49H	Benzyl N-[(2S)-3-(1H-indol-3-yl)-1-[[(1R)-3-methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxopropan-2-yl]carbamate	Investigative	127028814	C34H44BN3O5	585.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CNC5=CC=CC=C54)NC(=O)OCC6=CC=CC=C6	IC50 = 24547089.16 nM	Non binder
T49031	Proteasome beta-5	BMD6T8	N-[(2S)-1-[[(1R)-2-(4-Methylphenyl)-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]amino]-1-oxo-3-phenylpropan-2-yl]-1,2,3,4-tetrahydronaphthalene-2-carboxamide	Investigative	127030316	C39H47BN2O4	618.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=C(C=C4)C)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)C6CCC7=CC=CC=C7C6	IC50 = 862978547.8 nM	Non binder
T49031	Proteasome beta-5	BMO59X	Tert-butyl N-[(2S)-4-methyl-1-oxo-1-[[(1R)-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]pentyl]amino]pentan-2-yl]carbamate	Investigative	127028490	C26H47BN2O5	478.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CCCC)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C	IC50 = 20417379.45 nM	Non binder
T49031	Proteasome beta-5	BMW2Y6	Tert-butyl N-[(2S)-4-methyl-1-[[(1R)-2-(4-methylphenyl)-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]amino]-1-oxopentan-2-yl]carbamate	Investigative	127028492	C30H47BN2O5	526.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=C(C=C4)C)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C	IC50 = 2137962.09 nM	Non binder
T49031	Proteasome beta-5	BN1WX2	N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-3-naphthalen-2-yl-1-oxopropan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	49799953	C39H49BN2O4	620.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC5=CC=CC=C5C=C4)NC(=O)C6CCCC7=CC=CC=C67	IC50 = 131825673.9 nM	Non binder
T49031	Proteasome beta-5	BNSZ45	Tert-butyl N-[(2S)-3-(4-hydroxyphenyl)-1-[[(1R)-3-methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxopropan-2-yl]carbamate	Investigative	127030043	C29H45BN2O6	528.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=C(C=C4)O)NC(=O)OC(C)(C)C	IC50 = 61659500.19 nM	Non binder
T49031	Proteasome beta-5	BS6FO7	N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxo-3-phenylpropan-2-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide	Investigative	127030635	C35H47BN2O4	570.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)C5=CC=CC6=C5CCCC6	IC50 = 758577575 nM	Non binder
T49031	Proteasome beta-5	BTM08X	N-[(2S)-1-[[(1R)-2-(4-Fluorophenyl)-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]ethyl]amino]-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide	Investigative	127053229	C32H36BFN4O4	570.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC4=CC=C(C=C4)F)NC(=O)[C@H](CC5=CC=CC=C5)NC(=O)C6=NC=CN=C6	IC50 = 309029543.3 nM	Non binder
T49031	Proteasome beta-5	BW4ZI7	[(1R)-3-Methyl-1-[[(2S)-3-phenyl-2-[[(1S)-1,2,3,4-tetrahydronaphthalene-1-carbonyl]amino]propanoyl]amino]butyl]boronic acid	Investigative	44191199	C25H33BN2O4	436.4	B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)[C@H]2CCCC3=CC=CC=C23)(O)O	IC50 = 831763771.1 nM	Non binder
T49031	Proteasome beta-5	BWU0Q9	N-[(2S)-3-Methyl-1-[[(1R)-3-methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxobutan-2-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide	Investigative	127030318	C31H47BN2O4	522.5	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)C4=CC=CC5=C4CCCC5	IC50 = 144543977.1 nM	Non binder
T49031	Proteasome beta-5	BYB0C3	[(1R)-3-Methyl-1-[[(2S)-3-phenyl-2-(5,6,7,8-tetrahydronaphthalene-1-carbonylamino)propanoyl]amino]butyl]boronic acid	Investigative	44190247	C25H33BN2O4	436.4	B([C@H](CC(C)C)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=CC=CC3=C2CCCC3)(O)O	IC50 = 616595001.9 nM	Non binder
T49031	Proteasome beta-5	BZ1C4B	N-[(2S)-4-Methyl-1-[[(1R)-3-methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxopentan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053294	C32H49BN2O4	536.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)C4CCCC5=CC=CC=C45	IC50 = 70794578.44 nM	Non binder
T49031	Proteasome beta-5	BZB63C	N-[(2S)-1-[[(1R)-3-Methyl-1-[(1S,2S,8S)-2,9,9-trimethyl-3,5-dioxa-4-boratricyclo[6.1.1.02,6]decan-4-yl]butyl]amino]-1-oxo-3-phenylpropan-2-yl]-1,2,3,4-tetrahydronaphthalene-1-carboxamide	Investigative	127053267	C35H47BN2O4	570.6	B1(OC2C[C@@H]3C[C@H]([C@@]2(O1)C)C3(C)C)[C@H](CC(C)C)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)C5CCCC6=CC=CC=C56	IC50 = 239883291.9 nM	Non binder