TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T52297	Oxysterols receptor LXR-alpha	B2IZ4G	{3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-YL]phenyl}[(1-methyl-1H-indol-2-YL)methyl]amine	Investigative	45272392	C33H26F3N3	521.6	CN1C2=CC=CC=C2C=C1CNC3=CC=CC(=C3)C4=C5C=CC=C(C5=NC=C4CC6=CC=CC=C6)C(F)(F)F	IC50 = 1123000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	B2MWD6	3-Benzyl-4-[3-[(1-methylindol-2-yl)methoxy]phenyl]-8-(trifluoromethyl)cinnoline	Investigative	11857214	C32H24F3N3O	523.5	CN1C2=CC=CC=C2C=C1COC3=CC=CC(=C3)C4=C5C=CC=C(C5=NN=C4CC6=CC=CC=C6)C(F)(F)F	IC50 > 1000000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	B4BR1Q	3-Benzyl-4-(3-{[2-chloro-3-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline	Investigative	11853545	C30H19ClF6N2O	572.9	C1=CC=C(C=C1)CC2=NN=C3C(=C2C4=CC(=CC=C4)OCC5=C(C(=CC=C5)C(F)(F)F)Cl)C=CC=C3C(F)(F)F	IC50 = 2927000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	B4MAO9	3-Benzyl-8-chloro-4-[3-[[5-chloro-2-(trifluoromethyl)phenyl]methoxy]phenyl]cinnoline	Investigative	11854572	C29H19Cl2F3N2O	539.4	C1=CC=C(C=C1)CC2=NN=C3C(=C2C4=CC(=CC=C4)OCC5=C(C=CC(=C5)Cl)C(F)(F)F)C=CC=C3Cl	IC50 = 1826000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	B6P5SZ	3-Benzyl-8-chloro-4-(3-{[2-chloro-3-(trifluoromethyl)benzyl]oxy}phenyl)cinnoline	Investigative	11854570	C29H19Cl2F3N2O	539.4	C1=CC=C(C=C1)CC2=NN=C3C(=C2C4=CC(=CC=C4)OCC5=C(C(=CC=C5)C(F)(F)F)Cl)C=CC=C3Cl	IC50 = 837000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	B6QI0Y	3-Benzyl-4-{3-[(1-Methyl-1H-Indol-7-yl)Methoxy]Phenyl}-8-(Trifluoromethyl) Quinoline	Investigative	45270660	C33H25F3N2O	522.6	CN1C=CC2=C1C(=CC=C2)COC3=CC=CC(=C3)C4=C5C=CC=C(C5=NC=C4CC6=CC=CC=C6)C(F)(F)F	IC50 = 668000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	B7AF2U	3-Benzyl-4-(3-{[5-fluoro-2-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline	Investigative	11853793	C30H19F7N2O	556.5	C1=CC=C(C=C1)CC2=NN=C3C(=C2C4=CC(=CC=C4)OCC5=C(C=CC(=C5)F)C(F)(F)F)C=CC=C3C(F)(F)F	IC50 = 1194000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	B7IT8O	N-[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl]-N-[(1-methyl-1H-indol-7-yl)methyl]amine	Investigative	11854313	C31H25ClN4	489	CN1C=CC2=C1C(=CC=C2)CNC3=CC=CC(=C3)C4=C5C=CC=C(C5=NN=C4CC6=CC=CC=C6)Cl	IC50 > 1000000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	B7OID1	8-Chloro-4-(3-{[5-chloro-2-(trifluoromethyl)benzyl]oxy}phenyl)-3-phenylcinnoline	Investigative	45273240	C28H17Cl2F3N2O	525.3	C1=CC=C(C=C1)C2=NN=C3C(=C2C4=CC(=CC=C4)OCC5=C(C=CC(=C5)Cl)C(F)(F)F)C=CC=C3Cl	IC50 = 332000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	B8UB4M	3-Benzyl-4-(3-{[2-fluoro-3-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline	Investigative	11853546	C30H19F7N2O	556.5	C1=CC=C(C=C1)CC2=NN=C3C(=C2C4=CC(=CC=C4)OCC5=C(C(=CC=C5)C(F)(F)F)F)C=CC=C3C(F)(F)F	IC50 = 1336000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	BB5X6R	{3-[3-Benzyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}-[(1-methyl-1H-indol-7-yl)methyl]amine	Investigative	45273258	C33H26F3N3	521.6	CN1C=CC2=C1C(=CC=C2)CNC3=CC=CC(=C3)C4=C5C=CC=C(C5=NC=C4CC6=CC=CC=C6)C(F)(F)F	IC50 = 1415000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	BFG69D	[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][2-chloro-3-(trifluoromethyl)benzyl]amine	Investigative	11855620	C29H20Cl2F3N3	538.4	C1=CC=C(C=C1)CC2=NN=C3C(=C2C4=CC(=CC=C4)NCC5=C(C(=CC=C5)C(F)(F)F)Cl)C=CC=C3Cl	IC50 = 1124000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	BMC2H7	3-Benzyl-4-[3-[(1-methylindol-7-yl)methoxy]phenyl]-8-(trifluoromethyl)cinnoline	Investigative	11856960	C32H24F3N3O	523.5	CN1C=CC2=C1C(=CC=C2)COC3=CC=CC(=C3)C4=C5C=CC=C(C5=NN=C4CC6=CC=CC=C6)C(F)(F)F	IC50 > 1000000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	BR1D4C	[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][(1-methyl-1H-indol-2-yl)methyl]amine	Investigative	11855082	C31H25ClN4	489	CN1C2=CC=CC=C2C=C1CNC3=CC=CC(=C3)C4=C5C=CC=C(C5=NN=C4CC6=CC=CC=C6)Cl	IC50 = 603000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	BS03KW	3-Benzyl-8-chloro-4-(3-{[5-fluoro-2-(trifluoromethyl)benzyl]oxy}phenyl)cinnoline	Investigative	11854314	C29H19ClF4N2O	522.9	C1=CC=C(C=C1)CC2=NN=C3C(=C2C4=CC(=CC=C4)OCC5=C(C=CC(=C5)F)C(F)(F)F)C=CC=C3Cl	IC50 = 1191000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	BTK48R	3-Benzyl-4-(3-{[5-chloro-2-(trifluoromethyl)benzyl]oxy}-phenyl)-8-(trifluoromethyl)cinnoline	Investigative	11853795	C30H19ClF6N2O	572.9	C1=CC=C(C=C1)CC2=NN=C3C(=C2C4=CC(=CC=C4)OCC5=C(C=CC(=C5)Cl)C(F)(F)F)C=CC=C3C(F)(F)F	IC50 > 1000000 nM	Non binder
T52297	Oxysterols receptor LXR-alpha	BWS5V3	[3-(3-Benzyl-8-chlorocinnolin-4-yl)phenyl][5-fluoro-2-(trifluoromethyl)benzyl]amine	Investigative	11855623	C29H20ClF4N3	521.9	C1=CC=C(C=C1)CC2=NN=C3C(=C2C4=CC(=CC=C4)NCC5=C(C=CC(=C5)F)C(F)(F)F)C=CC=C3Cl	IC50 > 1000000 nM	Non binder