TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T55948 Organic cation transporter 3 D0U5SI Procainamide Approved 4913 C13H21N3O 235.33 CCN(CC)CCNC(=O)C1=CC=C(C=C1)N Ki = 738000 nM Non binder T55948 Organic cation transporter 3 D0V7CF Indinavir Approved 5362440 C36H47N5O4 613.8 CC(C)(C)NC(=O)[C@@H]1CN(CCN1C[C@H](C[C@@H](CC2=CC=CC=C2)C(=O)N[C@@H]3[C@@H](CC4=CC=CC=C34)O)O)CC5=CN=CC=C5 IC50 > 500000 nM Non binder T55948 Organic cation transporter 3 D0ZU9R Ritonavir Approved 392622 C37H48N6O5S2 720.9 CC(C)C1=NC(=CS1)CN(C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C[C@@H]([C@H](CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O IC50 > 300000 nM Non binder T55948 Organic cation transporter 3 B2EQD4 Guanidine Investigative 3520 CH5N3 59.07 C(=N)(N)N IC50 = 2200000 nM Non binder T55948 Organic cation transporter 3 BLB3Z0 N-(4-Benzylphenyl)guanidine Investigative 24801038 C14H15N3 225.29 C1=CC=C(C=C1)CC2=CC=C(C=C2)N=C(N)N IC50 = 452500 nM Non binder T55948 Organic cation transporter 3 D06PZZ [14C]TEA Investigative 5413 C8H20N+ 130.25 CC[N+](CC)(CC)CC Ki = 1372000 nM Non binder