TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T58992	Opioid receptor delta	B0QM7I	(S,E)-(2,3,5,6,7,9a-Hexahydro-1H-pyrrolo[1,2-a]azepin-9-yl)(2-hydroxy-6-methylphenyl)methanone	Investigative	46865104	C17H21NO2	271.35	CC1=C(C(=CC=C1)O)C(=O)C2=CCCCN3[C@H]2CCC3	Ki > 200000 nM	Non binder
T58992	Opioid receptor delta	B13PZS	3-[(1-Acetylpiperidin-4-yl)amino]-1-(1-cyclooctylpiperidin-4-yl)quinoxalin-2-one	Investigative	59451165	C28H41N5O2	479.7	CC(=O)N1CCC(CC1)NC2=NC3=CC=CC=C3N(C2=O)C4CCN(CC4)C5CCCCCCC5	Ki = 531427 nM	Non binder
T58992	Opioid receptor delta	B1GF8S	1-(1-Cyclooctylpiperidin-4-yl)-3-[[(2S)-2,3-dihydroxypropyl]amino]quinoxalin-2-one	Investigative	59451217	C24H36N4O3	428.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)NC[C@@H](CO)O	Ki = 530892 nM	Non binder
T58992	Opioid receptor delta	B1HE2R	2-[[4-[(1R,5S)-8-Cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxalin-2-yl]-(2-hydroxyethyl)amino]acetic acid	Investigative	59451133	C27H38N4O4	482.6	C1CCCC(CCC1)N2[C@@H]3CC[C@H]2CC(C3)N4C5=CC=CC=C5N=C(C4=O)N(CCO)CC(=O)O	Ki = 547704 nM	Non binder
T58992	Opioid receptor delta	B2Z4LO	Ethyl 4-[(1R,5S)-8-cyclooctyl-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxaline-2-carboxylate	Investigative	59450914	C26H35N3O3	437.6	CCOC(=O)C1=NC2=CC=CC=C2N(C1=O)C3C[C@H]4CC[C@@H](C3)N4C5CCCCCCC5	Ki = 530900 nM	Non binder
T58992	Opioid receptor delta	B47WLH	1-(1-Cyclooctylpiperidin-4-yl)-3-(2-methyl-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl)quinoxalin-2-one	Investigative	59451039	C28H41N5O	463.7	CN1CC2CN(CC2C1)C3=NC4=CC=CC=C4N(C3=O)C5CCN(CC5)C6CCCCCCC6	Ki = 519741 nM	Non binder
T58992	Opioid receptor delta	B65KDI	4-[1-(1-Ethylcyclooctyl)piperidin-4-yl]-3-oxoquinoxaline-2-carboxylic acid	Investigative	59451191	C24H33N3O3	411.5	CCC1(CCCCCCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)C(=O)O	Ki = 524333 nM	Non binder
T58992	Opioid receptor delta	B7EZ4L	Methyl 2-[[4-(1-cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]amino]-3-hydroxypropanoate	Investigative	59450928	C25H36N4O4	456.6	COC(=O)C(CO)NC1=NC2=CC=CC=C2N(C1=O)C3CCN(CC3)C4CCCCCCC4	Ki = 518930 nM	Non binder
T58992	Opioid receptor delta	B8X1QW	1-[1-(1-Adamantyl)piperidin-4-yl]-3-[[(2R)-2,3-dihydroxypropyl]amino]quinoxalin-2-one	Investigative	59451034	C26H36N4O3	452.6	C1CN(CCC1N2C3=CC=CC=C3N=C(C2=O)NC[C@H](CO)O)C45CC6CC(C4)CC(C6)C5	Ki = 535200 nM	Non binder
T58992	Opioid receptor delta	B9VCX0	(2-Hydroxy-6-methylphenyl)-[(8S)-5,6,7,8-tetrahydro-3H-pyrrolizin-1-yl]methanone	Investigative	46865103	C15H17NO2	243.3	CC1=C(C(=CC=C1)O)C(=O)C2=CCN3[C@H]2CCC3	Ki > 200000 nM	Non binder
T58992	Opioid receptor delta	BBD8P4	4-[(1R,5S)-9-(1-Adamantyl)-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Investigative	59451304	C27H33N3O3	447.6	C1C[C@@H]2CC(C[C@H](C1)N2C34CC5CC(C3)CC(C5)C4)N6C7=CC=CC=C7N=C(C6=O)C(=O)O	Ki = 525570 nM	Non binder
T58992	Opioid receptor delta	BE7LF0	3-Oxo-4-[1-(1-propylcyclooctyl)piperidin-4-yl]quinoxaline-2-carboxylic acid	Investigative	59451016	C25H35N3O3	425.6	CCCC1(CCCCCCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)C(=O)O	Ki = 537763 nM	Non binder
T58992	Opioid receptor delta	BF7L5Q	13-[2-Amino-3-(4-hydroxy-3-methoxy-phenyl)-propionylamino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triaza-cyclotetradecane-4-carboxylic acid	Investigative	44316562	C31H41N5O8S2	675.8	CC1([C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(SS1)(C)C)C(=O)O)CC2=CC=CC=C2)NC(=O)[C@H](CC3=CC(=C(C=C3)O)OC)N)C	IC50 = 600000 nM	Non binder
T58992	Opioid receptor delta	BMF6D3	(S)-(1,2,3,5,6,8a-Hexahydroindolizin-8-yl)(2-hydroxyphenyl)methanone	Investigative	46880272	C15H17NO2	243.3	C1C[C@H]2C(=CCCN2C1)C(=O)C3=CC=CC=C3O	Ki > 200000 nM	Non binder
T58992	Opioid receptor delta	BN05MI	Ethyl 2-[[4-(1-cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]amino]acetate	Investigative	59451166	C25H36N4O3	440.6	CCOC(=O)CNC1=NC2=CC=CC=C2N(C1=O)C3CCN(CC3)C4CCCCCCC4	Ki = 532394 nM	Non binder
T58992	Opioid receptor delta	BN70GY	10-Amino-9-(hydroxymethyl)-1-methyltricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol	Investigative	44301664	C15H21NO2	247.33	CC12CCC(C(C1)(CC3=C2C=C(C=C3)O)CO)N	Ki > 1000000 nM	Non binder
T58992	Opioid receptor delta	BO30CE	4-[(1R,5S)-8-(1-Adamantyl)-8-azabicyclo[3.2.1]octan-3-yl]-3-oxoquinoxaline-2-carboxylic acid	Investigative	70860777	C26H31N3O3	433.5	C1C[C@H]2CC(C[C@@H]1N2C34CC5CC(C3)CC(C5)C4)N6C7=CC=CC=C7N=C(C6=O)C(=O)O	Ki = 533800 nM	Non binder
T58992	Opioid receptor delta	BO67QS	1-(1-Cyclooctylpiperidin-4-yl)-3-[[(2R)-2,3-dihydroxypropyl]amino]quinoxalin-2-one	Investigative	59450973	C24H36N4O3	428.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)NC[C@H](CO)O	Ki = 528011 nM	Non binder
T58992	Opioid receptor delta	BR8G0S	2-[[4-(1-Cyclooctylpiperidin-4-yl)-3-oxoquinoxalin-2-yl]amino]acetamide	Investigative	59451293	C23H33N5O2	411.5	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)NCC(=O)N	Ki = 548766 nM	Non binder
T58992	Opioid receptor delta	BU1B5W	4-[(1S,5R)-9-Cyclooctyl-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl]-3-oxoquinoxaline-2-carboxylic acid	Investigative	59450954	C24H31N3O4	425.5	C1CCCC(CCC1)N2[C@@H]3CC(C[C@H]2COC3)N4C5=CC=CC=C5N=C(C4=O)C(=O)O	Ki = 533100 nM	Non binder
T58992	Opioid receptor delta	BU5S2W	(S)-(1,2,3,5,6,8a-Hexahydroindolizin-8-yl)(2-methoxy-6-methylphenyl)methanone	Investigative	46880271	C17H21NO2	271.35	CC1=C(C(=CC=C1)OC)C(=O)C2=CCCN3[C@H]2CCC3	Ki > 200000 nM	Non binder
T58992	Opioid receptor delta	BUL1Y5	9-(Hydroxymethyl)-1-methyl-10-(methylamino)tricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol	Investigative	44301653	C16H23NO2	261.36	CC12CCC(C(C1)(CC3=C2C=C(C=C3)O)CO)NC	Ki > 1000000 nM	Non binder
T58992	Opioid receptor delta	BV3R1S	1-(1-Cyclooctylpiperidin-4-yl)-3-(1,3-dihydroisoindol-2-yl)quinoxalin-2-one	Investigative	59451197	C29H36N4O	456.6	C1CCCC(CCC1)N2CCC(CC2)N3C4=CC=CC=C4N=C(C3=O)N5CC6=CC=CC=C6C5	Ki = 545749 nM	Non binder
T58992	Opioid receptor delta	BXDT49	10-(Dimethylamino)-9-(hydroxymethyl)-1-methyltricyclo[7.3.1.02,7]trideca-2(7),3,5-trien-4-ol	Investigative	44301963	C17H25NO2	275.4	CC12CCC(C(C1)(CC3=C2C=C(C=C3)O)CO)N(C)C	Ki > 1000000 nM	Non binder