TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T60529	Prostaglandin G/H synthase 1	D0NF1U	FENOFIBRIC ACID	Approved	64929	C17H15ClO4	318.7	CC(C)(C(=O)O)OC1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)Cl	IC50 = 950000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B01HUL	Sodium;2-[4-[(2-oxocyclopentyl)methyl]-2-[4-(trifluoromethoxy)phenyl]phenyl]propanoate	Investigative	56668661	C22H20F3NaO4	428.4	CC(C1=C(C=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)OC(F)(F)F)C(=O)[O-].[Na+]	IC50 = 515000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B14ORT	2-Methoxy-6-pentadecylbenzyl 2-benzoxazolyl sulfide	Investigative	44373310	C30H43NO2S	481.7	CCCCCCCCCCCCCCCC1=C(C(=CC=C1)OC)CSC2=NC3=CC=CC=C3O2	IC50 > 500000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B1FH9Q	N-Caffeoyl serotonin	Investigative	16659826	C19H18N2O4	338.4	C1=CC(=C(C=C1/C=C/C(=O)NCCC2=CNC3=C2C=C(C=C3)O)O)O	IC50 > 400000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B1I8GR	3-(2-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one	Investigative	44325888	C17H14O5S	330.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=CC=C3O	IC50 > 250000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B1K8DG	3-(3-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one	Investigative	44325870	C17H14O5S	330.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC(=CC=C3)O	IC50 > 250000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B21BLD	6-Methyl-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid	Investigative	21883595	C12H9F3O3	258.19	CC1=CC2=C(C=C1)OC(C(=C2)C(=O)O)C(F)(F)F	IC50 = 224000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B23WKL	3-[[1-(4-Chlorophenyl)triazol-4-yl]methyl]-6-methyl-1,3-benzoxazol-2-one	Investigative	76317113	C17H13ClN4O2	340.8	CC1=CC2=C(C=C1)N(C(=O)O2)CC3=CN(N=N3)C4=CC=C(C=C4)Cl	IC50 = 389200 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B2LR1U	N'-[(E)-(4-Oxo-4H-chromen-3-yl)methylidene]benzenecarbohydrazide	Investigative	9559931	C17H12N2O3	292.29	C1=CC=C(C=C1)C(=O)N/N=C/C2=COC3=CC=CC=C3C2=O	IC50 = 405960 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B36OSN	6-Formyl-2-trifluoromethyl-2H-chromene-3-carboxylic acid	Investigative	10016051	C12H7F3O4	272.18	C1=CC2=C(C=C1C=O)C=C(C(O2)C(F)(F)F)C(=O)O	IC50 = 500000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B3DXR7	4-[2-(5-Methylpyridin-2-yl)-4-(trifluoromethyl)imidazol-1-yl]benzenesulfonamide	Investigative	10691290	C16H13F3N4O2S	382.4	CC1=CN=C(C=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 302000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B58HMR	4,6-Dimethyl-2-[4-oxo-4-(4-phenylpiperazin-1-yl)butyl]-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	134147676	C22H26N4O2S	410.5	CC1=CC(=NC2=C1C(=O)N(S2)CCCC(=O)N3CCN(CC3)C4=CC=CC=C4)C	IC50 = 263026.8 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B5BQ1D	Atractylon	Investigative	3080635	C15H20O	216.32	CC1=COC2=C1C[C@H]3C(=C)CCC[C@@]3(C2)C	IC50 > 200000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B5JP4S	Sodium;2-[2-(4-methylphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56668670	C22H23NaO3	358.4	CC1=CC=C(C=C1)C2=C(C=CC(=C2)CC3CCCC3=O)C(C)C(=O)[O-].[Na+]	IC50 = 470000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B5L1JS	2,3-Dimethyl-4-phenyl-5-[4-(methylsulfonyl)phenyl]-4-isoxazoline	Investigative	10381921	C18H19NO3S	329.4	CC1C(=C(ON1C)C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=CC=C3	IC50 = 258110 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B5MNL4	Atractylenolide II	Investigative	14448070	C15H20O2	232.32	CC1=C2C[C@H]3C(=C)CCC[C@@]3(C[C@@H]2OC1=O)C	IC50 > 200000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B5XH0E	1-[4-(Methylsulfonyl)phenyl]-2-(3-chloro-4-methoxyphenyl)-4-(trifluoromethyl)-1H-imidazole	Investigative	10741315	C18H14ClF3N2O3S	430.8	COC1=C(C=C(C=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F)Cl	IC50 = 296000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B6IS4X	2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl]-4,6-dimethyl-isothiazolo[5,4-b]pyridin-3-one	Investigative	463829	C21H25ClN4OS	417	CC1=CC(=NC2=C1C(=O)N(S2)CCCN3CCN(CC3)C4=CC(=CC=C4)Cl)C	IC50 = 524807.46 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B6MLE0	Fraxetin	Investigative	5273569	C10H8O5	208.17	COC1=C(C(=C2C(=C1)C=CC(=O)O2)O)O	IC50 = 524000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B6V0ZS	2-Ethoxy-6-pentadecylbenzyl 5-nitro-1H-benzimidazole-2-yl sulfide	Investigative	44373312	C31H45N3O3S	539.8	CCCCCCCCCCCCCCCC1=C(C(=CC=C1)OCC)CSC2=NC3=C(N2)C=C(C=C3)[N+](=O)[O-]	IC50 > 500000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B6YRO1	Sodium;2-[2-(4-methylsulfanylphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56672143	C22H23NaO3S	390.5	CC(C1=C(C=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)SC)C(=O)[O-].[Na+]	IC50 = 575000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B74XWE	Thiazolidin-5-one	Investigative	20553328	C3H5NOS	103.15	C1C(=O)SCN1	IC50 = 540000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B7EOZ1	2-Ethoxy-6-pentadecylbenzyl 1H-benzimidazole-2-yl sulfide	Investigative	44373338	C31H46N2OS	494.8	CCCCCCCCCCCCCCCC1=C(C(=CC=C1)OCC)CSC2=NC3=CC=CC=C3N2	IC50 > 500000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B7RM5B	Methyl 2-acetoxy-3-(5-methoxy-5-oxopentyl)benzoate	Investigative	44249752	C16H20O6	308.33	CC(=O)OC1=C(C=CC=C1C(=O)OC)CCCCC(=O)OC	IC50 = 720000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B81XTW	2-[[1-(4-Ethylphenyl)triazol-4-yl]methylsulfanyl]-1,3-benzoxazole	Investigative	90643698	C18H16N4OS	336.4	CCC1=CC=C(C=C1)N2C=C(N=N2)CSC3=NC4=CC=CC=C4O3	IC50 = 246200 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B83PUM	4-[4,5-Difluoro-2-(6-methylpyridin-3-yl)phenyl]benzenesulfonamide	Investigative	10713528	C18H14F2N2O2S	360.4	CC1=NC=C(C=C1)C2=CC(=C(C=C2C3=CC=C(C=C3)S(=O)(=O)N)F)F	IC50 = 265000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B8UW9E	4-[2-(3-Methyl-pyridin-2-yl)-4-trifluoromethyl-imidazol-1-yl]-benzenesulfonamide	Investigative	9970134	C16H13F3N4O2S	382.4	CC1=C(N=CC=C1)C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 338000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B98IPY	1-(4-Methylsulfonylphenyl)-2-phenyl-4-(trifluoromethyl)imidazole	Investigative	9947305	C17H13F3N2O2S	366.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC=CC=C3)C(F)(F)F	IC50 = 723000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B9BSR8	4-(1-(4-(Aminosulfonyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-5-yl)benzoic acid	Investigative	10047220	C17H12F3N3O4S	411.4	C1=CC(=CC=C1C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F)C(=O)O	IC50 > 250000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B9K1DJ	Atractylenolide I	Investigative	5321018	C15H18O2	230.3	CC1=C2C[C@H]3C(=C)CCC[C@@]3(C=C2OC1=O)C	IC50 > 200000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	B9MJP7	4-(Dimethylamino)-2-methyl-5-(3-oxo-3-phenylprop-1-enyl)pyridazin-3(2H)-one	Investigative	44407686	C16H17N3O2	283.32	CN1C(=O)C(=C(C=N1)/C=C/C(=O)C2=CC=CC=C2)N(C)C	IC50 = 221300 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BB3EZ7	3-Methoxyacetaminophen	Investigative	3080594	C9H11NO3	181.19	CC(=O)NC1=CC(=C(C=C1)O)OC	IC50 = 234000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BB69RV	2-(3-Chlorophenyl)-1-(4-methylsulfonylphenyl)-4-(trifluoromethyl)imidazole	Investigative	9822332	C17H12ClF3N2O2S	400.8	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CC(=CC=C3)Cl)C(F)(F)F	IC50 = 360000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BB6EA1	1-[4-(3-Chlorophenyl)piperazin-1-yl]-4-[(4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl)oxy]butan-1-one	Investigative	134152086	C22H25ClN4O2S	445	CC1=CC(=NC2=C1C(=NS2)OCCCC(=O)N3CCN(CC3)C4=CC(=CC=C4)Cl)C	IC50 = 380189.4 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BC9S7J	2-[4-[4-(3-Chlorophenyl)piperazin-1-yl]-4-oxobutyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	134138064	C22H25ClN4O2S	445	CC1=CC(=NC2=C1C(=O)N(S2)CCCC(=O)N3CCN(CC3)C4=CC(=CC=C4)Cl)C	IC50 = 371535.23 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BCJ61T	Sodium;2-[4-[(2-oxocyclopentyl)methyl]-3-[4-(trifluoromethoxy)phenyl]phenyl]propanoate	Investigative	56675533	C22H20F3NaO4	428.4	CC(C1=CC(=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)OC(F)(F)F)C(=O)[O-].[Na+]	IC50 = 460000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BD65YV	3-(3,4-Difluoro-phenyl)-5-hydroxy-4-(4-methanesulfonyl-phenyl)-5-methyl-5H-furan-2-one	Investigative	21472759	C18H14F2O5S	380.4	CC1(C(=C(C(=O)O1)C2=CC(=C(C=C2)F)F)C3=CC=C(C=C3)S(=O)(=O)C)O	IC50 > 300000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BET3Q7	3-(4-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one	Investigative	10359269	C17H14O5S	330.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=C(C=C3)O	IC50 > 250000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BF5GM3	7,8-Dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid	Investigative	9818254	C11H5Cl2F3O3	313.05	C1=CC(=C(C2=C1C=C(C(O2)C(F)(F)F)C(=O)O)Cl)Cl	IC50 = 300000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BFE8Q7	3-(4-Chlorophenoxy)-6-methyl-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	11383735	C19H15ClO5S	390.8	CC1=CC(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)C)OC3=CC=C(C=C3)Cl	IC50 = 207000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BFM5P7	(1R,4Ar,7S)-7-Ethyl-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid	Investigative	44368313	C20H32O2	304.5	CC[C@]1(CC=C2C(C1)CCC3[C@]2(CCC[C@@]3(C)C(=O)O)C)C	IC50 = 229000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BG3UF4	Sodium;2-[2-(4-hydroxyphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	53248884	C21H21NaO4	360.4	CC(C1=C(C=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)O)C(=O)[O-].[Na+]	IC50 = 326000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BIA67D	(1R,4Ar,7S)-7-(2-Acetoxy-ethyl)-1,4a,7-trimethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydro-phenanthrene-1-carboxylic acid	Investigative	9820390	C22H34O4	362.5	CC(=O)OCC[C@]1(CC=C2C(C1)CCC3[C@]2(CCC[C@@]3(C)C(=O)O)C)C	IC50 = 265700 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BJ27AZ	Sodium;2-[4-[(2-oxocyclopentyl)methyl]-2-phenylphenyl]propanoate	Investigative	56665216	C21H21NaO3	344.4	CC(C1=C(C=C(C=C1)CC2CCCC2=O)C3=CC=CC=C3)C(=O)[O-].[Na+]	IC50 = 310000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BJ79VX	2-Ethoxy-6-pentadecylbenzyl 5-methoxy-1H-benzimidazole-2-yl sulfide	Investigative	44373654	C32H48N2O2S	524.8	CCCCCCCCCCCCCCCC1=C(C(=CC=C1)OCC)CSC2=NC3=C(N2)C=C(C=C3)OC	IC50 > 500000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BKCM19	2-[1-(4-Chlorobenzoyl)-2-phenylindol-3-yl]acetic acid	Investigative	57393522	C23H16ClNO3	389.8	C1=CC=C(C=C1)C2=C(C3=CC=CC=C3N2C(=O)C4=CC=C(C=C4)Cl)CC(=O)O	IC50 > 400000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BL2CU0	2-[3-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-oxopropyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	134143054	C22H25N3O4S	427.5	CC1=CC(=NC2=C1C(=O)N(S2)CCC(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C	IC50 = 301995.17 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BL70UK	3-[[1-(2-Chlorophenyl)triazol-4-yl]methyl]-6-methyl-1,3-benzoxazol-2-one	Investigative	76320832	C17H13ClN4O2	340.8	CC1=CC2=C(C=C1)N(C(=O)O2)CC3=CN(N=N3)C4=CC=CC=C4Cl	IC50 = 207360 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BMC5S8	2-(4-Methylphenyl)sulfonyl-3-naphthalen-2-yl-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706119	C21H17F3N2O2S	418.4	CC1=CC=C(C=C1)S(=O)(=O)N2C(CC(=N2)C(F)(F)F)C3=CC4=CC=CC=C4C=C3	IC50 > 500000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BN5P6S	3-(3,5-Dihydroxyphenyl)-6,8-dihydroxy-2H-1-benzopyran-2-one	Investigative	44406281	C15H10O6	286.24	C1=C(C=C(C=C1O)O)C2=CC3=CC(=CC(=C3OC2=O)O)O	IC50 = 285000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BN6UG4	1-(4-Methanesulfonyl-phenyl)-2-o-tolyl-4-trifluoromethyl-1H-imidazole	Investigative	10452350	C18H15F3N2O2S	380.4	CC1=CC=CC=C1C2=NC(=CN2C3=CC=C(C=C3)S(=O)(=O)C)C(F)(F)F	IC50 = 577000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BNK9H7	Sodium;2-[3-(4-methoxyphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56668666	C22H23NaO4	374.4	CC(C1=CC(=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)OC)C(=O)[O-].[Na+]	IC50 = 800000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BO18XN	Atractylenolide III	Investigative	155948	C15H20O3	248.32	CC1=C2C[C@H]3C(=C)CCC[C@@]3(C[C@@]2(OC1=O)O)C	IC50 > 200000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BOM70P	2-[(4-Cyclohexylpiperazin-1-yl)methyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	24848656	C19H28N4OS	360.5	CC1=CC(=NC2=C1C(=O)N(S2)CN3CCN(CC3)C4CCCCC4)C	IC50 = 660693.45 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BOVM36	Sodium;2-[3-(4-methylsulfanylphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56682184	C22H23NaO3S	390.5	CC(C1=CC(=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)SC)C(=O)[O-].[Na+]	IC50 = 758000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BP0Q9T	2-(2-Methoxy-6-pentadecyl-benzylsulfanyl)-5-nitro-1H-benzoimidazole	Investigative	44373350	C30H43N3O3S	525.7	CCCCCCCCCCCCCCCC1=C(C(=CC=C1)OC)CSC2=NC3=C(N2)C=C(C=C3)[N+](=O)[O-]	IC50 > 500000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BP40HL	Sodium;2-[4-[[(1R,2S)-2-hydroxycyclopentyl]methyl]-2-(4-hydroxyphenyl)phenyl]propanoate	Investigative	56682186	C21H23NaO4	362.4	CC(C1=C(C=C(C=C1)C[C@H]2CCC[C@@H]2O)C3=CC=C(C=C3)O)C(=O)[O-].[Na+]	IC50 = 650000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BPE27C	5-Ethyl-1,2,4-tris(4-hydroxyphenyl)-1H-imidazole	Investigative	135502974	C23H20N2O3	372.4	CCC1=C(N=C(N1C2=CC=C(C=C2)O)C3=CC=C(C=C3)O)C4=CC=C(C=C4)O	IC50 > 200000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BR2GD9	4-[5-Pyridin-4-yl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide	Investigative	10666704	C15H11F3N4O2S	368.3	C1=CC(=CC=C1N2C(=CC(=N2)C(F)(F)F)C3=CC=NC=C3)S(=O)(=O)N	IC50 = 209000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BR4IG7	2-(5-Methoxy-1H-benzimidazole-2-ylthiomethyl)-3-pentadecylphenol	Investigative	10051539	C30H44N2O2S	496.7	CCCCCCCCCCCCCCCC1=C(C(=CC=C1)O)CSC2=NC3=C(N2)C=C(C=C3)OC	IC50 = 384000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BR8Z4X	2-[1-(4-Chlorobenzoyl)-2-ethylindol-3-yl]acetic acid	Investigative	53249089	C19H16ClNO3	341.8	CCC1=C(C2=CC=CC=C2N1C(=O)C3=CC=C(C=C3)Cl)CC(=O)O	IC50 > 400000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BS16FD	Sodium;2-[2-iodo-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56668663	C15H16INaO3	394.18	CC(C1=C(C=C(C=C1)CC2CCCC2=O)I)C(=O)[O-].[Na+]	IC50 = 270000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BTKQ54	N-[4-[2-(3,4-Dichlorophenyl)ethyl]phenyl]-4-hydroxy-1,1-dioxo-2H-1lambda6,2-benzothiazine-3-carboxamide	Investigative	54728405	C23H18Cl2N2O4S	489.4	C1=CC=C2C(=C1)C(=C(NS2(=O)=O)C(=O)NC3=CC=C(C=C3)CCC4=CC(=C(C=C4)Cl)Cl)O	IC50 = 489000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BTP1R2	N-Sinapoyl Serotonin	Investigative	46892801	C21H22N2O5	382.4	COC1=CC(=CC(=C1O)OC)/C=C/C(=O)NCCC2=CNC3=C2C=C(C=C3)O	IC50 > 400000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BU2XW4	2-[2-[4-(3-Chlorophenyl)piperazin-1-yl]-2-oxoethyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	20876816	C20H21ClN4O2S	416.9	CC1=CC(=NC2=C1C(=O)N(S2)CC(=O)N3CCN(CC3)C4=CC(=CC=C4)Cl)C	IC50 = 229086.77 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BU4V3N	2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]-3-oxopropyl]-1,2-benzothiazol-3-one	Investigative	134154737	C20H20ClN3O2S	401.9	C1CN(CCN1C2=CC(=CC=C2)Cl)C(=O)CCN3C(=O)C4=CC=CC=C4S3	IC50 = 301995.17 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BU6B7N	4-[5-(7-Methyl-benzo[1,3]dioxol-5-yl)-3-trifluoromethyl-pyrazol-1-yl]-benzenesulfonamide	Investigative	10646043	C18H14F3N3O4S	425.4	CC1=CC(=CC2=C1OCO2)C3=CC(=NN3C4=CC=C(C=C4)S(=O)(=O)N)C(F)(F)F	IC50 = 674000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BV6KB3	2-Methoxy-6-pentadecylbenzyl 5-methyl-1H-benzimidazole-2-yl sulfide	Investigative	44373038	C31H46N2OS	494.8	CCCCCCCCCCCCCCCC1=C(C(=CC=C1)OC)CSC2=NC3=C(N2)C=C(C=C3)C	IC50 > 500000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BW01AE	Acanthol	Investigative	9882419	C20H32O	288.5	C[C@]1(CCC[C@@]2(C1CCC3C2=CC[C@](C3)(C)C=C)C)CO	IC50 = 791100 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BY68CN	Osthole	Investigative	10228	C15H16O3	244.28	CC(=CCC1=C(C=CC2=C1OC(=O)C=C2)OC)C	IC50 > 200000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BYA10O	Chembl4161755	Investigative	145958203	C22H20ClNO3	381.8	CC1(CC2=C(C(=O)C1)C3=C(N2C(=O)C4=CC=C(C=C4)Cl)C=CC(=C3)OC)C	IC50 = 201000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BYKX28	2-Amino-2-[1-(3-fluorophenyl)-2-methyl-5-(4-methylsulfonylphenyl)pyrrol-3-yl]-N-(2-hydroxyethyl)acetamide	Investigative	73333399	C22H24FN3O4S	445.5	CC1=C(C=C(N1C2=CC(=CC=C2)F)C3=CC=C(C=C3)S(=O)(=O)C)C(C(=O)NCCO)N	IC50 = 300000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	BZXD35	2-Methoxy-6-pentadecylbenzyl 2-benzothiazolyl sulfide	Investigative	10255326	C30H43NOS2	497.8	CCCCCCCCCCCCCCCC1=C(C(=CC=C1)OC)CSC2=NC3=CC=CC=C3S2	IC50 > 500000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	D02FEF	4-(3-methoxy-benzylideneamino)-benzenesulfonamide	Investigative	404378	C14H14N2O3S	290.34	COC1=CC=CC(=C1)C=NC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 383360 nM	Non binder
T60529	Prostaglandin G/H synthase 1	D07LUJ	URSOLIC ACID	Investigative	64945	C30H48O3	456.7	C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O	IC50 = 210000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	D07QIU	4-(4-methoxy-benzylideneamino)-benzenesulfonamide	Investigative	625902	C14H14N2O3S	290.34	COC1=CC=C(C=C1)C=NC2=CC=C(C=C2)S(=O)(=O)N	IC50 = 313830 nM	Non binder
T60529	Prostaglandin G/H synthase 1	D0F6CD	SEROTONIN	Investigative	5202	C10H12N2O	176.21	C1=CC2=C(C=C1O)C(=CN2)CCN	IC50 > 400000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	D0SJ2Q	OLEANOLIC_ACID	Investigative	10494	C30H48O3	456.7	C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O	IC50 = 380000 nM	Non binder
T60529	Prostaglandin G/H synthase 1	D0V9EN	3,4-Dihydroxycinnamic Acid	Investigative	689043	C9H8O4	180.16	C1=CC(=C(C=C1/C=C/C(=O)O)O)O	IC50 > 400000 nM	Non binder