TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T61243	Metabotropic glutamate receptor 7	D00ENY	L-Glutamic Acid	Approved	33032	C5H9NO4	147.13	C(CC(=O)O)[C@@H](C(=O)O)N	EC50 > 500000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B0BG6A	(2S,4R)-2-Amino-4-(2-cyanoethyl)pentanedioic acid	Investigative	71574837	C8H12N2O4	200.19	C(C[C@H](C[C@@H](C(=O)O)N)C(=O)O)C#N	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B0RA6L	(2S,4R)-4-(3-Hydroxy-3-oxopropyl)glutamic Acid	Investigative	24905705	C8H13NO6	219.19	C(CC(=O)O)[C@H](C[C@@H](C(=O)O)N)C(=O)O	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B2L1ZS	(S)-2-Amino-2-((1S,2R)-2-phosphonocyclopropyl)acetic acid	Investigative	44406221	C5H10NO5P	195.11	C1[C@H]([C@@H]1P(=O)(O)O)[C@@H](C(=O)O)N	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B2QAS9	(2S,4R)-2-Amino-4-(2-aminoethyl)pentanedioic acid	Investigative	71574839	C7H14N2O4	190.2	C(CN)[C@H](C[C@@H](C(=O)O)N)C(=O)O	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B2X3BM	(2S)-2-Amino-4-[hydroxy-[hydroxy-(3-nitrophenyl)methyl]phosphoryl]butanoic acid	Investigative	46918013	C11H15N2O7P	318.22	C1=CC(=CC(=C1)[N+](=O)[O-])C(O)P(=O)(CC[C@@H](C(=O)O)N)O	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B3KSN6	(4r)-4-{3-[Hydroxy(Methyl)amino]-3-Oxopropyl}-L-Glutamic Acid	Investigative	70789291	C9H16N2O6	248.23	CN(C(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O)O	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B5CY2P	(1S,2S)-1-Amino-2-(phosphonomethyl)cyclopropanecarboxylic acid	Investigative	16747848	C5H10NO5P	195.11	C1[C@@H]([C@@]1(C(=O)O)N)CP(=O)(O)O	EC50 = 625000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B5R8IH	(2S)-2-Amino-4-[hydroxy-[hydroxy-(5-nitrofuran-2-yl)methyl]phosphoryl]butanoic acid	Investigative	16061421	C9H13N2O8P	308.18	C1=C(OC(=C1)[N+](=O)[O-])C(O)P(=O)(CC[C@@H](C(=O)O)N)O	EC50 = 1970000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B5T6CU	(2S,4S)-2-Amino-4-(2,2-diphenylethyl)pentanedioic Acid	Investigative	10359073	C19H21NO4	327.4	C1=CC=C(C=C1)C(C[C@@H](C[C@@H](C(=O)O)N)C(=O)O)C2=CC=CC=C2	Ki > 300000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B6NEY7	1,2,4-Butanetricarboxylic acid, 4-amino-, (2S,4S)-	Investigative	24905703	C7H11NO6	205.17	C([C@@H](CC(=O)O)C(=O)O)[C@@H](C(=O)O)N	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B7D3CJ	(2S,4R)-2-Amino-4-(3-aminopropyl)pentanedioic acid	Investigative	71574840	C8H16N2O4	204.22	C(C[C@H](C[C@@H](C(=O)O)N)C(=O)O)CN	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B7H8KS	2-Amino-2-[(1R,2R,3S)-2-phenyl-3-phosphonocyclopropyl]acetic acid	Investigative	16739372	C11H14NO5P	271.21	C1=CC=C(C=C1)[C@H]2[C@@H]([C@H]2P(=O)(O)O)C(C(=O)O)N	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	B91OPF	(1R,2S)-2-Amino-2-carboxycyclopropane-1-acetic acid	Investigative	45082292	C6H9NO4	159.14	C1[C@@H]([C@@]1(C(=O)O)N)CC(=O)O	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	BD04NQ	(1R,2S)-1-Amino-2-(phosphonomethyl)cyclopropanecarboxylic acid	Investigative	16748099	C5H10NO5P	195.11	C1[C@@H]([C@]1(C(=O)O)N)CP(=O)(O)O	EC50 > 3000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	BE5F7O	2-Amino-2-[(1S,2S,3R)-2-phenyl-3-phosphonocyclopropyl]acetic acid	Investigative	44429217	C11H14NO5P	271.21	C1=CC=C(C=C1)[C@@H]2[C@H]([C@@H]2P(=O)(O)O)C(C(=O)O)N	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	BE91JP	(2S,4R)-2-Amino-4-[3-(hydroxyamino)-3-oxopropyl]pentanedioic acid	Investigative	71574838	C8H14N2O6	234.21	C(CC(=O)NO)[C@H](C[C@@H](C(=O)O)N)C(=O)O	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	BJ2SP4	(S)-2-Amino-2-((1R,2S)-2-phosphonocyclopropyl)acetic acid	Investigative	44406220	C5H10NO5P	195.11	C1[C@@H]([C@H]1P(=O)(O)O)[C@@H](C(=O)O)N	EC50 = 700000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	BJ8Y6O	(S)-3,5-Dihydroxyphenylglycine	Investigative	443586	C8H9NO4	183.16	C1=C(C=C(C=C1O)O)[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	BP8AW5	(2S)-2-Amino-4-[hydroxy-[(R)-hydroxy-(4-hydroxy-3-nitrophenyl)methyl]phosphoryl]butanoic acid	Investigative	137654697	C11H15N2O8P	334.22	C1=CC(=C(C=C1[C@H](O)P(=O)(CC[C@@H](C(=O)O)N)O)[N+](=O)[O-])O	EC50 = 295000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	BQIC40	2-Amino-2,3-methano-4-phosphonobutanoic acid	Investigative	125799	C5H10NO5P	195.11	C1[C@H]([C@]1(C(=O)O)N)CP(=O)(O)O	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	BUBT35	(1S,2S)-1-Amino-2-(carboxymethyl)cyclopropane-1-carboxylic acid	Investigative	11768848	C6H9NO4	159.14	C1[C@H]([C@@]1(C(=O)O)N)CC(=O)O	EC50 > 1000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	BV24EJ	(1S,2R)-1-Amino-2-(phosphonomethyl)cyclopropanecarboxylic acid	Investigative	16747847	C5H10NO5P	195.11	C1[C@H]([C@@]1(C(=O)O)N)CP(=O)(O)O	EC50 = 602000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	BW1M4L	(2S)-2-Amino-4-[hydroxy-[hydroxy-(5-nitrothiophen-3-yl)methyl]phosphoryl]butanoic acid	Investigative	92044496	C9H13N2O7PS	324.25	C1=C(SC=C1C(O)P(=O)(CC[C@@H](C(=O)O)N)O)[N+](=O)[O-]	EC50 = 418000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	BZ07DY	2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid	Investigative	6604795	C8H12N2O4	200.19	CC1=C(C(=O)NO1)CC[C@@H](C(=O)O)N	Ki > 5000000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	D0EK6P	(2R,4R)-4-aminopyrrolidine-2,4-dicarboxylate	Investigative	5310984	C6H10N2O4	174.15	C1[C@@H](NC[C@]1(C(=O)O)N)C(=O)O	Ki > 300000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	D0OV2V	LY307452	Investigative	6324634	C21H25NO4	355.4	C1=CC=C(C=C1)C(CCC[C@@H](C[C@@H](C(=O)O)N)C(=O)O)C2=CC=CC=C2	Ki > 300000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	D0P2VP	(2S,1'R,2'S)-2-(2'-phosphonocyclopropyl)glycine	Investigative	11708219	C5H10NO5P	195.11	C1[C@@H]([C@H]1P(=O)(O)O)C(C(=O)O)N	EC50 = 700000 nM	Non binder
T61243	Metabotropic glutamate receptor 7	D0W3PY	ACPT-I	Investigative	6604820	C8H11NO6	217.18	C1[C@H]([C@H](CC1(C(=O)O)N)C(=O)O)C(=O)O	EC50 = 280000 nM	Non binder