TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T61339	Lysosomal alpha-glucosidase	D0AD5C	Acarbose	Approved	41774	C25H43NO18	645.6	C[C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@H](O[C@@H]([C@@H]([C@H]2O)O)O[C@@H]3[C@H](OC([C@@H]([C@H]3O)O)O)CO)CO)O)O)N[C@H]4C=C([C@H]([C@@H]([C@H]4O)O)O)CO	IC50 = 817380 nM	Non binder
T61339	Neutral alpha-glucosidase AB	B0V3HQ	1,4,5,6-Tetradeoxy-1,4-imino-D-erythro-hexitol	Investigative	11804793	C6H13NO2	131.17	CC[C@@H]1[C@H]([C@H](CN1)O)O	IC50 = 800000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B0WY8X	(5-Benzyliminopyrrolidin-2-yl)methanol	Investigative	136016326	C12H16N2O	204.27	C1CC(=NCC2=CC=CC=C2)NC1CO	Ki = 4000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B1KF4V	2-Benzyliminopiperidine	Investigative	3238144	C12H16N2	188.27	C1CCN=C(C1)NCC2=CC=CC=C2	Ki = 3700000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B2GYI0	N-((1S,3R,4S,5R,6R,7S)-4,5-Dihydroxy-3-(hydroxymethyl)-2-oxabicyclo[4.1.0]heptan-7-yl)5-(adamant-1-yl-methoxy)pentanamide	Investigative	45375977	C23H37NO6	423.5	C1C2CC3CC1CC(C2)(C3)COCCCCC(=O)N[C@H]4[C@H]5[C@@H]4O[C@@H]([C@H]([C@@H]5O)O)CO	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B2QM4I	2,5-Dideoxy-2,5-Imino-D-Glucitol	Investigative	445074	C6H13NO4	163.17	C([C@@H]1[C@H]([C@@H]([C@@H](N1)CO)O)O)O	IC50 = 300000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B37TSH	(1S,3R,4S,5R,6R,7S)-7-[5-(1-Adamantylmethoxy)pentylamino]-3-(hydroxymethyl)-2-oxabicyclo[4.1.0]heptane-4,5-diol	Investigative	45375976	C23H39NO5	409.6	C1C2CC3CC1CC(C2)(C3)COCCCCCN[C@H]4[C@H]5[C@@H]4O[C@@H]([C@H]([C@@H]5O)O)CO	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B3R2DQ	N-Butyl-L-ido-1-deoxynojirimycin	Investigative	23622616	C10H21NO4	219.28	CCCCN1C[C@@H]([C@H]([C@@H]([C@@H]1CO)O)O)O	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B3ZE0W	(2S,3S,4R,5S)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol	Investigative	11816841	C10H21NO4	219.28	CCCCN1C[C@@H]([C@H]([C@H]([C@@H]1CO)O)O)O	IC50 = 500000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B45ORD	5-Methylpiperidine-3,4-diol	Investigative	10011928	C6H13NO2	131.17	CC1CNCC(C1O)O	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B4BIJ0	(6-Benzyliminopiperidin-2-yl)methanol	Investigative	136016327	C13H18N2O	218.29	C1CC(NC(=NCC2=CC=CC=C2)C1)CO	Ki = 700000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B58IZE	N-[5-(Adamantan-1-yl-methoxy)-pentyl]-L-ido-1-deoxynojirimycin	Investigative	11258014	C22H39NO5	397.5	C1[C@@H]([C@H]([C@@H]([C@@H](N1CCCCCOCC23CC4CC(C2)CC(C4)C3)CO)O)O)O	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B6AMS3	(1S,3R,4S,5R,6R,7S)-N-Butyl-4,5-dihydroxy-3-(hydroxymethyl)-2-oxabicyclo[4.1.0]heptan-7-amine	Investigative	45483515	C11H21NO4	231.29	CCCCN[C@H]1[C@H]2[C@@H]1O[C@@H]([C@H]([C@@H]2O)O)CO	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B7EP6S	5-Aminocyclopentane-1,2,3,4-tetrol	Investigative	13880378	C5H11NO4	149.15	C1(C(C(C(C1O)O)O)O)N	IC50 > 300000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B7U3LJ	5-Methylene-piperidine-3,4-diol	Investigative	44367875	C6H11NO2	129.16	C=C1CNCC(C1O)O	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B8ACZ7	[(2R,3R)-4-[(2S,3S,4S)-3,4-Dihydroxy-2-(hydroxymethyl)thiolan-1-ium-1-yl]-1,3-dihydroxybutan-2-yl] sulfate	Investigative	9880776	C9H18O9S2	334.4	C1[C@H]([C@@H]([C@@H]([S+]1C[C@@H]([C@@H](CO)OS(=O)(=O)[O-])O)CO)O)O	IC50 = 3400000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B8OIH9	1-Butyl-5-methyl-piperidine-3,4-diol	Investigative	44368231	C10H21NO2	187.28	CCCCN1CC(C(C(C1)O)O)C	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	B96ETW	2-Phenylamino-4,5,6,6a-tetrahydro-3aH-cyclopentaoxazole-4,5,6-triol	Investigative	44322665	C12H14N2O4	250.25	C1=CC=C(C=C1)NC2=NC3C(C(C(C3O2)O)O)O	IC50 > 300000 nM	Non binder
T61339	Neutral alpha-glucosidase AB	BCV61X	(2S,3R,4R,5S)-2-Fluoromethyl-piperidine-3,4,5-triol	Investigative	11116404	C6H12FNO3	165.16	C1[C@@H]([C@H]([C@@H]([C@H](N1)CF)O)O)O	Ki = 340000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	BFI2G6	2-Anilino-6a-(hydroxymethyl)-3a,4,5,6-tetrahydrocyclopenta[d][1,3]oxazole-4,5,6-triol	Investigative	21479008	C13H16N2O5	280.28	C1=CC=C(C=C1)NC2=NC3C(C(C(C3(O2)CO)O)O)O	IC50 > 300000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	BFWT18	N-((1S,3R,4S,5R,6R,7S)-4,5-Dihydroxy-3-(hydroxymethyl)-2-oxabicyclo[4.1.0]heptan-7-yl)butyramide	Investigative	45483523	C11H19NO5	245.27	CCCC(=O)N[C@H]1[C@H]2[C@@H]1O[C@@H]([C@H]([C@@H]2O)O)CO	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	BG7WR8	2-Anilino-4-(hydroxymethyl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazole-5,6-diol	Investigative	44322890	C13H16N2O4	264.28	C1=CC=C(C=C1)NC2=NC3C(C(C(C3O2)O)O)CO	IC50 > 300000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	BG8P9B	3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2S,3R,4R,5S)-	Investigative	10888248	C6H13NO4	163.17	C1[C@@H]([C@H]([C@@H]([C@@H](N1)CO)O)O)O	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	BIUM90	N-[5-(Adamantan-1-yl-methoxy)-pentyl]-L-altro-1-deoxynojirimycin	Investigative	44820252	C22H39NO5	397.5	C1[C@@H]([C@H]([C@H]([C@@H](N1CCCCCOCC23CC4CC(C2)CC(C4)C3)CO)O)O)O	IC50 = 500000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	BK1PI2	(1S,3R,4S,5R,6R,7S)-4,5-Dihydroxy-3-(hydroxymethyl)-2-oxabicyclo[4.1.0]heptan-7-amine	Investigative	11600756	C7H13NO4	175.18	C([C@@H]1[C@H]([C@@H]([C@H]2[C@@H]([C@H]2O1)N)O)O)O	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	BK7QO5	2-Anilino-6-(hydroxymethyl)-3a,4,5,6a-tetrahydrocyclopenta[d][1,3]oxazole-4,5,6-triol	Investigative	44322630	C13H16N2O5	280.28	C1=CC=C(C=C1)NC2=NC3C(C(C(C3O2)(CO)O)O)O	IC50 > 300000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	BKGR50	5-Methoxy-piperidine-3,4-diol	Investigative	44368232	C6H13NO3	147.17	COC1CNCC(C1O)O	IC50 > 1000000 nM	Non binder
T61339	Neutral alpha-glucosidase AB	BL3Q2W	(2R,3R,4R,5S)-2-Methylpiperidine-3,4,5-triol	Investigative	10351835	C6H13NO3	147.17	C[C@@H]1[C@H]([C@@H]([C@H](CN1)O)O)O	Ki = 1560000 nM	Non binder
T61339	Neutral alpha-glucosidase AB	BN6B3O	(6S,7R,8R)-Octahydro-indolizine-1,6,7,8-tetraol	Investigative	44338548	C8H15NO4	189.21	C1CN2C[C@@H]([C@H]([C@@H](C2C1O)O)O)O	Ki > 1500000 nM	Non binder
T61339	Neutral alpha-glucosidase AB	BVXL68	Fagomine	Investigative	72259	C6H13NO3	147.17	C1CN[C@@H]([C@H]([C@@H]1O)O)CO	IC50 = 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	BWJC90	1-Butyl-piperidine-3,4,5-triol	Investigative	44368239	C9H19NO3	189.25	CCCCN1CC(C(C(C1)O)O)O	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	BX25YQ	3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2S,3S,4R,5S)-	Investigative	11105683	C6H13NO4	163.17	C1[C@@H]([C@H]([C@H]([C@@H](N1)CO)O)O)O	IC50 > 1000000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	D00YEV	BAICALEIN	Investigative	5281605	C15H10O5	270.24	C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O	IC50 = 500000 nM	Non binder
T61339	Lysosomal alpha-glucosidase	D0R8TR	1,5-Dideoxy-1,5-imino-D-xylitol	Investigative	445612	C5H11NO3	133.15	C1[C@H](C([C@H](CN1)O)O)O	IC50 > 1000000 nM	Non binder