TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T62820	Metabotropic glutamate receptor 2	B0A5EK	(3-Amino-3-methylbutyl)phosphonic acid	Investigative	18756981	C5H14NO3P	167.14	CC(C)(CCP(=O)(O)O)N	Ki = 447000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B1U2ST	(2R,4R)-4-Amino-1-methylpyrrolidine-2,4-dicarboxylic acid	Investigative	44302818	C7H12N2O4	188.18	CN1C[C@](C[C@@H]1C(=O)O)(C(=O)O)N	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B1X8RG	(2R,4R)-4-Amino-1-biphenyl-2-ylmethyl-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302608	C19H20N2O4	340.4	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=CC=C2C3=CC=CC=C3)C(=O)O	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B29QMH	(2R)-3-(3''-Carboxybicyclo[1.1.1]pentyl)alanine	Investigative	44569827	C9H13NO4	199.2	C1C2(CC1(C2)C(=O)O)C[C@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B2L1ZS	(S)-2-Amino-2-((1S,2R)-2-phosphonocyclopropyl)acetic acid	Investigative	44406221	C5H10NO5P	195.11	C1[C@H]([C@@H]1P(=O)(O)O)[C@@H](C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B2MHI8	Benzylamino-(3-hydroxy-isoxazol-5-yl)-acetic acid	Investigative	15840277	C12H12N2O4	248.23	C1=CC=C(C=C1)CNC(C2=CC(=O)NO2)C(=O)O	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B2RYP6	2-Aminooctanedioic acid	Investigative	77937	C8H15NO4	189.21	C(CCC(C(=O)O)N)CCC(=O)O	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B2Y1QJ	2-[(1R,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	10752213	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@H]([C@H]2C(=O)O)[C@@H](C(=O)O)N	EC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B3BD1R	2-[(1S,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10513894	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@@H]([C@@H]2C(=O)O)[C@H](C(=O)O)N	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B48TJE	(2R,4R)-4-Amino-1-(3-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302605	C13H15ClN2O4	298.72	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC(=CC=C2)Cl)C(=O)O	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B4SK1A	(2S)-2-(3''-Carboxymethylbicyclo[1.1.1]pentyl)glycine	Investigative	44569859	C10H15NO4	213.23	C1C2(CC1(C2)CC(=O)O)C[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B5J7WM	2-[(1R,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10489914	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@H]([C@H]2C(=O)O)[C@H](C(=O)O)N	EC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B5XW4D	(2R)-2-(3''-Carboxymethylbicyclo[1.1.1]pentyl)glycine	Investigative	44569860	C10H15NO4	213.23	C1C2(CC1(C2)CC(=O)O)C[C@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B6KD8I	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1R,2S)-	Investigative	17758443	C5H9NO5S	195.2	C1[C@@H]([C@H]1S(=O)(=O)O)[C@@H](C(=O)O)N	Ki = 235000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B7GRY1	(2S,3S)-3-(Carboxymethyl)azetidine-2-carboxylic acid	Investigative	2733519	C6H9NO4	159.14	C1[C@@H]([C@H](N1)C(=O)O)CC(=O)O	IC50 > 600000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B7H8KS	2-Amino-2-[(1R,2R,3S)-2-phenyl-3-phosphonocyclopropyl]acetic acid	Investigative	16739372	C11H14NO5P	271.21	C1=CC=C(C=C1)[C@H]2[C@@H]([C@H]2P(=O)(O)O)C(C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B7TMV2	3-[(R)-Amino(carboxy)methyl]bicyclo[1.1.1]pentane-1-carboxylic acid	Investigative	10241509	C8H11NO4	185.18	C1C2(CC1(C2)C(=O)O)[C@H](C(=O)O)N	EC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B8CUY3	2-[(1S,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	7157252	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@@H]([C@@H]2C(=O)O)[C@@H](C(=O)O)N	EC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B8GS1W	2-[(1R,2S,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10704895	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@H]([C@H]2C(=O)O)[C@H](C(=O)O)N	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B8PEG2	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1S,2R)-	Investigative	17758444	C5H9NO5S	195.2	C1[C@H]([C@@H]1S(=O)(=O)O)[C@H](C(=O)O)N	Ki > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B96LOR	D-2-Aminoadipic acid	Investigative	165627	C6H11NO4	161.16	C(C[C@H](C(=O)O)N)CC(=O)O	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B9BM4Y	Ethylamino-(3-hydroxy-isoxazol-5-yl)-acetic acid	Investigative	10103891	C7H10N2O4	186.17	CCNC(C1=CC(=O)NO1)C(=O)O	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	B9DR6Z	(S)-2-Amino-5-phosphonopentanoic acid	Investigative	1617110	C5H12NO5P	197.13	C(C[C@@H](C(=O)O)N)CP(=O)(O)O	Ki = 205000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BA5F1H	(1R,4S,5R,6S)-3-Azabicyclo[3.3.0]octane-4,6-dicarboxylic acid	Investigative	11543205	C9H13NO4	199.2	C1C[C@@H]([C@H]2[C@@H]1CN[C@@H]2C(=O)O)C(=O)O	EC50 = 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BA8XK5	2-[(1R,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10681240	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@H]([C@@H]2C(=O)O)[C@H](C(=O)O)N	EC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BBF7L9	(S)-Hibo	Investigative	10012356	C6H8N2O4	172.14	C1=C(ONC1=O)C[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BCYB02	(2R,4R)-4-Amino-1-(2,4-dichloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302896	C13H14Cl2N2O4	333.16	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=C(C=C(C=C2)Cl)Cl)C(=O)O	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BD08XI	(2R,4R)-4-Amino-1-(3-phenyl-propyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302929	C15H20N2O4	292.33	C1[C@@H](N(C[C@]1(C(=O)O)N)CCCC2=CC=CC=C2)C(=O)O	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BD93ST	2-[(1R,2R,3S)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	10489913	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@H]([C@@H]2C(=O)O)[C@@H](C(=O)O)N	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BDX8L5	(2R,1S,2R,3S)-2-(2-Carboxy-3-phenylcyclopropyl)glycine	Investigative	10059959	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@@H]([C@@H]2C(=O)O)[C@H](C(=O)O)N	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BE5F7O	2-Amino-2-[(1S,2S,3R)-2-phenyl-3-phosphonocyclopropyl]acetic acid	Investigative	44429217	C11H14NO5P	271.21	C1=CC=C(C=C1)[C@@H]2[C@H]([C@@H]2P(=O)(O)O)C(C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BEM28T	(1R,2S)-1-Amino-2-[(4-oxo-1,2,5-thiadiazol-3-yl)methyl]cyclopropane-1-carboxylic acid;hydrochloride	Investigative	118718091	C7H10ClN3O3S	251.69	C1[C@H]([C@]1(C(=O)O)N)CC2=NSNC2=O.Cl	EC50 = 251000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BEW0U5	(RS)-3-Hydroxyphenylglycine	Investigative	1217	C8H9NO3	167.16	C1=CC(=CC(=C1)O)C(C(=O)O)N	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BF1ZB7	(2R,4R)-4-Amino-1-(4-chloro-benzyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302932	C13H15ClN2O4	298.72	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=C(C=C2)Cl)C(=O)O	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BFLU56	(R)-Ampa	Investigative	6604707	C7H10N2O4	186.17	CC1=C(C(=O)NO1)C[C@H](C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BGC85U	2-Amino-2-[(1R,2S,3S)-2-phenyl-3-phosphonocyclopropyl]acetic acid	Investigative	44429224	C11H14NO5P	271.21	C1=CC=C(C=C1)[C@@H]2[C@@H]([C@H]2P(=O)(O)O)C(C(=O)O)N	EC50 = 320000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BGQN61	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1R,2S)-	Investigative	17758445	C5H9NO5S	195.2	C1[C@@H]([C@H]1S(=O)(=O)O)[C@H](C(=O)O)N	Ki > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BH3E4M	(S)-4-((1-Carboxyethyl)amino)benzoic acid	Investigative	22884216	C10H11NO4	209.2	C[C@@H](C(=O)O)NC1=CC=C(C=C1)C(=O)O	IC50 = 339000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BH41XD	2-Aminoheptanedioic acid	Investigative	101122	C7H13NO4	175.18	C(CCC(=O)O)CC(C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BHS53B	(2R,4R)-4-Amino-1-benzhydrylpyrrolidine-2,4-dicarboxylic acid	Investigative	49799828	C19H20N2O4	340.4	C1[C@@H](N(C[C@]1(C(=O)O)N)C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BI2F3N	2-[(1S,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	10513896	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@@H]([C@H]2C(=O)O)[C@@H](C(=O)O)N	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BI56LB	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1R,2R)-	Investigative	17758556	C5H9NO5S	195.2	C1[C@@H]([C@@H]1S(=O)(=O)O)[C@@H](C(=O)O)N	Ki > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BJ2SP4	(S)-2-Amino-2-((1R,2S)-2-phosphonocyclopropyl)acetic acid	Investigative	44406220	C5H10NO5P	195.11	C1[C@@H]([C@H]1P(=O)(O)O)[C@@H](C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BJ59AS	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1S,2R)-	Investigative	17758554	C5H9NO5S	195.2	C1[C@H]([C@@H]1S(=O)(=O)O)[C@@H](C(=O)O)N	Ki > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BJ8Y6O	(S)-3,5-Dihydroxyphenylglycine	Investigative	443586	C8H9NO4	183.16	C1=C(C=C(C=C1O)O)[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BK1E2B	alpha-Amino-3-(hydroxy)-5-methyl-4-isoxazoleacetic acid	Investigative	173564	C6H8N2O4	172.14	CC1=C(C(=O)NO1)C(C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BKY9E8	4-Carboxyphenylglycine	Investigative	5115	C9H9NO4	195.17	C1=CC(=CC=C1C(C(=O)O)N)C(=O)O	IC50 = 577000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BLVS56	(1r,3r)-1-Aminocyclopentane-1,3-dicarboxylic acid	Investigative	231345	C7H11NO4	173.17	C1C[C@@](C[C@@H]1C(=O)O)(C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BNM4E5	2-[(1S,2S,3S)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10513895	C12H13NO4	235.24	C1=CC=C(C=C1)[C@H]2[C@@H]([C@H]2C(=O)O)[C@H](C(=O)O)N	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BO1SZ9	(2R,4R)-4-Amino-1-biphenyl-4-ylmethyl-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302913	C19H20N2O4	340.4	C1[C@@H](N(C[C@]1(C(=O)O)N)CC2=CC=C(C=C2)C3=CC=CC=C3)C(=O)O	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BO68UI	(3-Hydroxy-isoxazol-5-yl)-methylamino-acetic acid	Investigative	10374869	C6H8N2O4	172.14	CNC(C1=CC(=O)NO1)C(=O)O	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BO9D5E	2-[(1R,2R,3R)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	10752214	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@H]([C@@H]2C(=O)O)[C@@H](C(=O)O)N	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BOCA73	(2R,4R)-4-Amino-1-ethylpyrrolidine-2,4-dicarboxylic acid	Investigative	44302837	C8H14N2O4	202.21	CCN1C[C@](C[C@@H]1C(=O)O)(C(=O)O)N	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BODA53	(2S,4R)-4-(2,2-Diphenylethylamino-3-oxopropyl)glutamic acid	Investigative	24905650	C22H26N2O5	398.5	C1=CC=C(C=C1)C(CNC(=O)CC[C@H](C[C@@H](C(=O)O)N)C(=O)O)C2=CC=CC=C2	IC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BP0UA4	1-Amino-3-phosphono-3-cyclopentene-1-carboxylic acid	Investigative	10262421	C6H10NO5P	207.12	C1C=C(CC1(C(=O)O)N)P(=O)(O)O	EC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BP9BL1	(2S)-3-(3''-Carboxybicyclo[1.1.1]pentyl)alanine	Investigative	44569826	C9H13NO4	199.2	C1C2(CC1(C2)C(=O)O)C[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BP9I2D	(1R,2S,4R,5S)-2-Amino-bicyclo[2.1.1]hexane-2,5-dicarboxylic acid	Investigative	10465017	C8H11NO4	185.18	C1[C@@H]2C[C@]([C@H]1[C@H]2C(=O)O)(C(=O)O)N	EC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BQ8ZP4	2-Amino-2-[(1S,2R,3R)-2-phenyl-3-phosphonocyclopropyl]acetic acid	Investigative	44429225	C11H14NO5P	271.21	C1=CC=C(C=C1)[C@H]2[C@H]([C@@H]2P(=O)(O)O)C(C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BR89DT	(1S,2S)-4-Aminocyclopentane-1,2,4-tricarboxylic acid	Investigative	10656383	C8H11NO6	217.18	C1[C@@H]([C@H](CC1(C(=O)O)N)C(=O)O)C(=O)O	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BRSO72	(S)-2-Amino-3-(4-butyl-3-hydroxy-isoxazol-5-yl)-propionic acid	Investigative	10263168	C10H16N2O4	228.24	CCCCC1=C(ONC1=O)C[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BSKL06	2-[(1S,2S,3R)-2-Carboxy-3-phenylcyclopropyl]-D-glycine	Investigative	10704896	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@@H]([C@H]2C(=O)O)[C@H](C(=O)O)N	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BSWF59	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1S,2S)-	Investigative	17758555	C5H9NO5S	195.2	C1[C@H]([C@H]1S(=O)(=O)O)[C@H](C(=O)O)N	Ki > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BV17EG	1-Amino-3-phosphono-2-cyclopentene-1-carboxylic acid	Investigative	10375719	C6H10NO5P	207.12	C1CC(C=C1P(=O)(O)O)(C(=O)O)N	IC50 > 200000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BVM18G	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaR,1R,2R)-	Investigative	17758449	C5H9NO5S	195.2	C1[C@@H]([C@@H]1S(=O)(=O)O)[C@H](C(=O)O)N	Ki > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BWC90O	2-Amino-bicyclo[3.2.0]heptane-2,7-dicarboxylic acid	Investigative	44322843	C9H13NO4	199.2	C1C[C@](C2C1C[C@@H]2C(=O)O)(C(=O)O)N	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BXIR36	2-Amino-6-(3-hydroxy-5-methylisoxazol-4-yl)hexanoic acid	Investigative	10609381	C10H16N2O4	228.24	CC1=C(C(=O)NO1)CCCCC(C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BY4U5X	Cyclopropaneacetic acid, alpha-amino-2-sulfo-, (alphaS,1S,2S)-	Investigative	17758450	C5H9NO5S	195.2	C1[C@H]([C@H]1S(=O)(=O)O)[C@@H](C(=O)O)N	Ki > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BYE7U4	(2R,4R)-4-Amino-1-(3,3-diphenyl-propyl)-pyrrolidine-2,4-dicarboxylic acid	Investigative	44302855	C21H24N2O4	368.4	C1[C@@H](N(C[C@]1(C(=O)O)N)CCC(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O	IC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BZ07DY	2-Amino-4-(3-hydroxy-5-methyl-isoxazol-4-yl)-butyric acid	Investigative	6604795	C8H12N2O4	200.19	CC1=C(C(=O)NO1)CC[C@@H](C(=O)O)N	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BZ67QI	2-Amino-5-(3-hydroxy-5-methyl-isoxazol-4-yl)-pentanoic acid	Investigative	44338561	C9H14N2O4	214.22	CC1=C(C(=O)NO1)CCCC(C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BZP84A	2-[(1R,2S,3R)-2-Carboxy-3-phenylcyclopropyl]-L-glycine	Investigative	10198574	C12H13NO4	235.24	C1=CC=C(C=C1)[C@@H]2[C@H]([C@H]2C(=O)O)[C@@H](C(=O)O)N	EC50 > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	BZPS47	L-Homocysteic acid	Investigative	177491	C4H9NO5S	183.19	C(CS(=O)(=O)O)[C@@H](C(=O)O)N	Ki > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	D04JKL	AIDA	Investigative	2071	C11H11NO4	221.21	C1CC(C2=C1C=C(C=C2)C(=O)O)(C(=O)O)N	Ki > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	D08CAB	D-aspartic acid	Investigative	83887	C4H7NO4	133.1	C([C@H](C(=O)O)N)C(=O)O	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	D09AQK	(R,S)-4-phosphonophenylglycine	Investigative	4545574	C8H10NO5P	231.14	C1=CC(=CC=C1C(C(=O)O)N)P(=O)(O)O	Ki > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	D0L0YF	homo-AMPA	Investigative	4236420	C8H12N2O4	200.19	CC1=C(C(=O)NO1)CCC(C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	D0O1AK	D-glutamic acid	Investigative	23327	C5H9NO4	147.13	C(CC(=O)O)[C@H](C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	D0OH2P	(S)-(+)-CBPG	Investigative	5311040	C8H11NO4	185.18	C1C2(CC1(C2)C(=O)O)[C@@H](C(=O)O)N	Ki > 300000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	D0OT9B	L-aspartic acid	Investigative	5960	C4H7NO4	133.1	C([C@@H](C(=O)O)N)C(=O)O	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	D0P2VP	(2S,1'R,2'S)-2-(2'-phosphonocyclopropyl)glycine	Investigative	11708219	C5H10NO5P	195.11	C1[C@@H]([C@H]1P(=O)(O)O)C(C(=O)O)N	EC50 > 1000000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	D0P3XO	(S)-4CPG	Investigative	5311459	C9H9NO4	195.17	C1=CC(=CC=C1[C@@H](C(=O)O)N)C(=O)O	Ki = 577000 nM	Non binder
T62820	Metabotropic glutamate receptor 2	D0T5SU	(S)-AMPA	Investigative	158397	C7H10N2O4	186.17	CC1=C(C(=O)NO1)C[C@@H](C(=O)O)N	EC50 > 1000000 nM	Non binder