TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T63484	Glucose-6-phosphate dehydrogenase	D0H5HO	ANDROSTERONE	Phase 3	5879	C19H30O2	290.4	C[C@]12CC[C@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)O	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	B0A7FZ	(3S,5S,8R,9S,10S,13S,14S,17R)-10,13-Dimethylspiro[1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-17,2'-oxetane]-3-ol	Investigative	57521582	C21H34O2	318.5	C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]45CCO5)C)O	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	B1AID4	N-[(3S,5S,8R,9S,10S,13S,14S,17S)-17-Acetyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]acetamide	Investigative	57521801	C23H37NO2	359.5	CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@@H](C4)NC(=O)C)C)C	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	B1WU6S	N-[(3R,5S,8R,9S,10S,13S,14S)-10,13-Dimethyl-17-oxo-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl]methanesulfonamide	Investigative	57522029	C20H33NO3S	367.5	C[C@]12CC[C@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)NS(=O)(=O)C	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	B26UAC	3-[(3S,5S,8R,9S,10S,13S,14S)-10,13-Dimethyl-17-oxo-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl]-1,1-dimethylurea	Investigative	57521688	C22H36N2O2	360.5	C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)NC(=O)N(C)C	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	B2VZ3N	(3S,8R,9S,10R,13S,14S,17R)-10,13-Dimethylspiro[1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-17,2'-oxetane]-3-ol	Investigative	70690523	C21H32O2	316.5	C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]45CCO5)C)O	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	B5G0FY	(3R,5S,8R,9S,10S,13S,14S)-3-Amino-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-one;hydrochloride	Investigative	57522026	C19H32ClNO	325.9	C[C@]12CC[C@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)N.Cl	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	B5VH7Z	3beta-Amino-5alpha-pregnane-20-one	Investigative	57521800	C21H35NO	317.5	CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@@H](C4)N)C)C	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	B7IZN8	(3S,8R,9S,10R,13S,14S,17S)-10,13-Dimethylspiro[1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthrene-17,2'-oxirane]-3-ol	Investigative	44542342	C20H30O2	302.5	C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]45CO5)C)O	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BCD41J	17beta-(2-Oxopropyl)-5alpha-androstane-3beta-ol	Investigative	57521581	C22H36O2	332.5	CC(=O)C[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@@H](C4)O)C)C	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BD4F1P	Chembl4169301	Investigative	145953919	C10H17NO7S	295.31	CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CS(=O)(=O)CCC#N)O)O)O	Ki > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BE08CA	3beta-Amino-5alpha-androstane-17-one	Investigative	11426281	C19H31NO	289.5	C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)N	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BM09QT	3-[(3S,5S,8R,9S,10S,13S,14S,17S)-17-Acetyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]-1,1-dimethylurea	Investigative	57521901	C24H40N2O2	388.6	CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@@H](C4)NC(=O)N(C)C)C)C	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BM41UZ	Chembl4172838	Investigative	145950768	C9H19NO5S	253.32	CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CSCCN)O)O)O	Ki > 2000000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BPUT65	5alpha-Androstan-17-one	Investigative	101927	C19H30O	274.4	C[C@]12CCCC[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BQ4WO5	Chembl4164794	Investigative	145958583	C9H20N2O7S	300.33	CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CNS(=O)(=O)CCN)O)O)O	Ki > 400000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BQT5A3	(3R,5S,8R,9S,10S,13S,14S)-10,13-Dimethyl-17-oxo-3-(sulfamoylamino)-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene	Investigative	57522030	C19H32N2O3S	368.5	C[C@]12CC[C@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)NS(=O)(=O)N	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BR67DB	3beta-Hydroxy-16alpha,17alpha-epoxy-5alpha-pregnan-20-one	Investigative	11870468	C21H32O3	332.5	CC(=O)[C@]12[C@H](O1)C[C@@H]3[C@@]2(CC[C@H]4[C@H]3CC[C@@H]5[C@@]4(CC[C@@H](C5)O)C)C	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BT5OI9	Chembl4159624	Investigative	145958859	C10H17NO5S	263.31	CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CSCCC#N)O)O)O	Ki > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BTA1M5	1-[(3R,5S,8R,9S,10S,13S,14S)-10,13-Dimethyl-17-oxo-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-3-yl]-3-ethylurea	Investigative	57522028	C22H36N2O2	360.5	CCNC(=O)N[C@@H]1CC[C@]2([C@H](C1)CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C)C	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BV6M3Q	1-[(3S,5S,8R,9S,10S,13S,14S,17R)-3-Hydroxy-17-methoxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthren-17-yl]ethanone	Investigative	57521583	C22H36O3	348.5	CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@@H](C4)O)C)C)OC	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BVN53S	Chembl4162165	Investigative	145959704	C10H21N3O5S	295.36	CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CSCCN=C(N)N)O)O)O	Ki > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BX2W5T	Methyl N-[(3S,5S,8R,9S,10S,13S,14S,17S)-17-acetyl-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]carbamate	Investigative	57521902	C23H37NO3	375.5	CC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@@H](C4)NC(=O)OC)C)C	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BY0Z1N	(3S,5S,8R,9S,10S,13S,14S,17S)-10,13-Dimethylspiro[1,2,3,4,5,6,7,8,9,11,12,14,15,16-tetradecahydrocyclopenta[a]phenanthrene-17,2'-oxirane]-3-ol	Investigative	15481096	C20H32O2	304.5	C[C@]12CC[C@@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]45CO5)C)O	IC50 > 200000 nM	Non binder
T63484	Glucose-6-phosphate dehydrogenase	BYR15N	CID 70084189	Investigative	70084189	C23H36O4	376.5	CC(=O)OCC(=O)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@@H](C4)O)C)C	IC50 > 200000 nM	Non binder