TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T63967	Neuronal acetylcholine receptor alpha-4/beta-2	B21FGK	3-((S)-1-Methyl-pyrrolidin-2-ylmethoxy)-5-propyl-pyridine	Investigative	44318740	C14H22N2O	234.34	CCCC1=CC(=CN=C1)OC[C@@H]2CCCN2C	EC50 > 1000000 nM	Non binder
T63967	Neuronal acetylcholine receptor alpha-4/beta-2	B2SZH5	2-((R)-1-Methyl-pyrrolidin-2-yl)-furo[3,2-b]pyridine	Investigative	44324548	C12H14N2O	202.25	CN1CCC[C@@H]1C2=CC3=C(O2)C=CC=N3	EC50 > 1000000 nM	Non binder
T63967	Neuronal acetylcholine receptor alpha-4/beta-2	B78ZQS	2-Bromo-3-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridine	Investigative	44318972	C11H15BrN2O	271.15	CN1CCC[C@H]1COC2=C(N=CC=C2)Br	EC50 > 1000000 nM	Non binder
T63967	Neuronal acetylcholine receptor alpha-4/beta-2	B87XHQ	4-Bromo-3-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridine	Investigative	21309700	C11H15BrN2O	271.15	CN1CCC[C@H]1COC2=C(C=CN=C2)Br	EC50 > 1000000 nM	Non binder
T63967	Neuronal acetylcholine receptor alpha-4/beta-2	BA8GJ9	3-Butyl-5-((S)-1-methyl-pyrrolidin-2-ylmethoxy)-pyridine	Investigative	10083372	C15H24N2O	248.36	CCCCC1=CC(=CN=C1)OC[C@@H]2CCCN2C	EC50 > 1000000 nM	Non binder
T63967	Neuronal acetylcholine receptor alpha-4/beta-2	BG5X0N	Benzoic acid [(2S)-1-methylpyrrolidine-2-yl]methyl ester	Investigative	73351944	C13H17NO2	219.28	CN1CCC[C@H]1COC(=O)C2=CC=CC=C2	IC50 = 313000 nM	Non binder
T63967	Neuronal acetylcholine receptor alpha-4/beta-2	BJ1P2K	1-(3-(Dimethylamino)butyl)-3-phenylurea	Investigative	44570099	C13H21N3O	235.33	CC(CCNC(=O)NC1=CC=CC=C1)N(C)C	Ki = 300000 nM	Non binder
T63967	Neuronal acetylcholine receptor alpha-4/beta-2	BVU0X6	(5S)-Spiro[1,3-oxazolidine-5,3'-1-azabicyclo[2.2.2]octane]-2-one	Investigative	5310971	C9H14N2O2	182.22	C1CN2CCC1[C@@]3(C2)CNC(=O)O3	IC50 > 2000000 nM	Non binder
T63967	Neuronal acetylcholine receptor alpha-4/beta-2	BWQ23J	3-(4-Chlorophenyl)-5-[(1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octan-2-yl]-1,2-oxazole	Investigative	11474847	C24H25ClN2O	392.9	CC1=CC=C(C=C1)[C@H]2C[C@@H]3CC[C@H]([C@H]2C4=CC(=NO4)C5=CC=C(C=C5)Cl)N3C	IC50 = 942000 nM	Non binder