TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T64205 Signal transducer and activator of transcription 1 B19YXC 4-[(2S)-2-[(4-Cyanophenyl)formamido]-2-{[(1S)-3-methyl-1-[(pyridin-4-ylmethyl)carbamoyl]butyl]carbamoyl}ethyl]phenoxyphosphonic acid Investigative 24768189 C29H32N5O7P 593.6 CC(C)C[C@@H](C(=O)NCC1=CC=NC=C1)NC(=O)[C@H](CC2=CC=C(C=C2)OP(=O)(O)O)NC(=O)C3=CC=C(C=C3)C#N IC50 = 402000 nM Non binder T64205 Signal transducer and activator of transcription 1 B9N0XM 4-[(2S)-2-[(4-Cyanophenyl)formamido]-2-{[(1S)-1-(cyclohexylcarbamoyl)-3-methylbutyl]carbamoyl}ethyl]phenoxyphosphonic acid Investigative 24768185 C29H37N4O7P 584.6 CC(C)C[C@@H](C(=O)NC1CCCCC1)NC(=O)[C@H](CC2=CC=C(C=C2)OP(=O)(O)O)NC(=O)C3=CC=C(C=C3)C#N IC50 = 605000 nM Non binder T64205 Signal transducer and activator of transcription 1 BADT57 4-[(2S)-2-[(4-Cyanophenyl)formamido]-2-{[(1S)-3-methyl-1-[(2-methylpropyl)carbamoyl]butyl]carbamoyl}ethyl]phenoxyphosphonic acid Investigative 24768188 C27H35N4O7P 558.6 CC(C)C[C@@H](C(=O)NCC(C)C)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C2=CC=C(C=C2)C#N IC50 = 250000 nM Non binder T64205 Signal transducer and activator of transcription 1 BD0ZL6 4-[(2S)-2-[(4-Cyanophenyl)formamido]-2-{[(1S)-1-[(3-methoxyphenyl)carbamoyl]-3-methylbutyl]carbamoyl}ethyl]phenoxyphosphonic acid Investigative 16730520 C30H33N4O8P 608.6 CC(C)C[C@@H](C(=O)NC1=CC(=CC=C1)OC)NC(=O)[C@H](CC2=CC=C(C=C2)OP(=O)(O)O)NC(=O)C3=CC=C(C=C3)C#N IC50 = 560000 nM Non binder T64205 Signal transducer and activator of transcription 1 BE8N9O 4-[(2S)-2-{[(1S)-1-(Benzylcarbamoyl)-3-methylbutyl]carbamoyl}-2-[(4-cyanophenyl)formamido]ethyl]phenoxyphosphonic acid Investigative 24768187 C30H33N4O7P 592.6 CC(C)C[C@@H](C(=O)NCC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=C(C=C2)OP(=O)(O)O)NC(=O)C3=CC=C(C=C3)C#N IC50 = 760000 nM Non binder T64205 Signal transducer and activator of transcription 1 BK1R4J 4-[(2S)-2-[(4-Cyanophenyl)formamido]-2-{[(1S)-1-[(3-hydroxypropyl)carbamoyl]-3-methylbutyl]carbamoyl}ethyl]phenoxyphosphonic acid Investigative 24768184 C26H33N4O8P 560.5 CC(C)C[C@@H](C(=O)NCCCO)NC(=O)[C@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C2=CC=C(C=C2)C#N IC50 = 210000 nM Non binder T64205 Signal transducer and activator of transcription 1 BN5I9K 4-[(2S)-2-[(4-Cyanophenyl)formamido]-2-{[(1S)-3-methyl-1-(phenylcarbamoyl)butyl]carbamoyl}ethyl]phenoxyphosphonic acid Investigative 24768186 C29H31N4O7P 578.6 CC(C)C[C@@H](C(=O)NC1=CC=CC=C1)NC(=O)[C@H](CC2=CC=C(C=C2)OP(=O)(O)O)NC(=O)C3=CC=C(C=C3)C#N IC50 = 380000 nM Non binder