TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T66665	Prostaglandin G/H synthase 2	D0KP0U	PMID26394986-Compound-22	Patented	2662	C17H14F3N3O2S	381.4	CC1=CC=C(C=C1)C2=CC(=NN2C3=CC=C(C=C3)S(=O)(=O)N)C(F)(F)F	IC50 = 390000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B0UJI7	4,6-Dimethyl-2-[3-oxo-3-(4-phenylpiperazin-1-yl)propyl]-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	134134738	C21H24N4O2S	396.5	CC1=CC(=NC2=C1C(=O)N(S2)CCC(=O)N3CCN(CC3)C4=CC=CC=C4)C	IC50 = 281838.29 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B0YKS9	N-(Cyclohexylmethyl)-2-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-4-amine	Investigative	44456666	C19H22F3N3O2S	413.5	CS(=O)(=O)C1=CC=C(C=C1)C2=NC(=CC(=N2)NCC3CCCCC3)C(F)(F)F	IC50 = 675678.34 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B1OWF8	2,3-Diphenylthiophene	Investigative	2801736	C16H12S	236.3	C1=CC=C(C=C1)C2=C(SC=C2)C3=CC=CC=C3	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B1YWX4	1-Tert-Butyloxycarbonyl-2-bromo-4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)pyrrole	Investigative	10097252	C22H21BrFNO4S	494.4	CC(C)(C)OC(=O)N1C(=CC(=C1C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F)Br	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B2ENM1	(2-Methylsulfanylphenyl) 2-bromoacetate	Investigative	10563335	C9H9BrO2S	261.14	CSC1=CC=CC=C1OC(=O)CBr	IC50 = 510000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B2LR1U	N'-[(E)-(4-Oxo-4H-chromen-3-yl)methylidene]benzenecarbohydrazide	Investigative	9559931	C17H12N2O3	292.29	C1=CC=C(C=C1)C(=O)N/N=C/C2=COC3=CC=CC=C3C2=O	IC50 = 802320 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B2R3UD	4-[4-(Benzylamino)-6-(trifluoromethyl)pyrimidin-2-yl]benzenesulfonamide	Investigative	44456801	C18H15F3N4O2S	408.4	C1=CC=C(C=C1)CNC2=NC(=NC(=C2)C(F)(F)F)C3=CC=C(C=C3)S(=O)(=O)N	IC50 = 300303.23 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B3O7KQ	5-Chloro-3-(4-ethylphenyl)-2-[4-(methanesulfonyl)phenyl]-4H-pyran-4-one	Investigative	44309929	C20H17ClO4S	388.9	CCC1=CC=C(C=C1)C2=C(OC=C(C2=O)Cl)C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 720111.92 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B3S2QY	2-Benzyl-4''-methanesulfonyl-biphenyl	Investigative	44384330	C20H18O2S	322.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2CC3=CC=CC=C3	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B3Z2MD	Sodium;2-[4-[(2-oxocyclopentyl)methyl]-3-phenylphenyl]propanoate	Investigative	56665210	C21H21NaO3	344.4	CC(C1=CC(=C(C=C1)CC2CCCC2=O)C3=CC=CC=C3)C(=O)[O-].[Na+]	IC50 = 290000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B4DCG1	1-[5-Bromo-3-(4-fluorophenyl)-2-(4-methylsulfonylphenyl)pyrrol-1-yl]ethanone	Investigative	10071673	C19H15BrFNO3S	436.3	CC(=O)N1C(=CC(=C1C2=CC=C(C=C2)S(=O)(=O)C)C3=CC=C(C=C3)F)Br	IC50 = 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B58HMR	4,6-Dimethyl-2-[4-oxo-4-(4-phenylpiperazin-1-yl)butyl]-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	134147676	C22H26N4O2S	410.5	CC1=CC(=NC2=C1C(=O)N(S2)CCCC(=O)N3CCN(CC3)C4=CC=CC=C4)C	IC50 = 389045.14 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B5DQG7	4-[(4,6-Dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl)oxy]butanoic acid	Investigative	134141655	C12H14N2O3S	266.32	CC1=CC(=NC2=C1C(=NS2)OCCCC(=O)O)C	IC50 = 245470.89 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B5I3RX	4-(4''-Methanesulfonyl-biphenyl-2-yl)-pyridine	Investigative	44383014	C18H15NO2S	309.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2C3=CC=NC=C3	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B5JP4S	Sodium;2-[2-(4-methylphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56668670	C22H23NaO3	358.4	CC1=CC=C(C=C1)C2=C(C=CC(=C2)CC3CCCC3=O)C(C)C(=O)[O-].[Na+]	IC50 = 540000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B5SB2E	Arenarioside	Investigative	44584310	C34H44O19	756.7	C[C@H]1[C@@H]([C@H]([C@H](C(O1)O[C@@H]2[C@H]([C@@H](O[C@@H]([C@H]2OC(=O)/C=C/C3=CC(=C(C=C3)O)O)CO[C@H]4[C@@H]([C@H]([C@@H](CO4)O)O)O)OCCC5=CC(=C(C=C5)O)O)O)O)O)O	IC50 = 600000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B61BNA	[2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]-(3-fluorophenyl)methanone;hydrochloride	Investigative	46906735	C34H37ClF2N2O5	627.1	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=CC(=CC=C6)F.Cl	IC50 = 357200 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B63QJT	3-(2,3-Dihydro-1,4-benzodioxin-5-yl)-2-(4-methylphenyl)sulfonyl-5-(trifluoromethyl)-3,4-dihydropyrazole	Investigative	118706122	C19H17F3N2O4S	426.4	CC1=CC=C(C=C1)S(=O)(=O)N2C(CC(=N2)C(F)(F)F)C3=C4C(=CC=C3)OCCO4	IC50 > 500000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B6V0ZS	2-Ethoxy-6-pentadecylbenzyl 5-nitro-1H-benzimidazole-2-yl sulfide	Investigative	44373312	C31H45N3O3S	539.8	CCCCCCCCCCCCCCCC1=C(C(=CC=C1)OCC)CSC2=NC3=C(N2)C=C(C=C3)[N+](=O)[O-]	IC50 = 384000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B71LJO	2-[3-[4-(3-Chlorophenyl)piperazin-1-yl]-3-oxopropyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	134154144	C21H23ClN4O2S	431	CC1=CC(=NC2=C1C(=O)N(S2)CCC(=O)N3CCN(CC3)C4=CC(=CC=C4)Cl)C	IC50 = 295120.92 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B79PZH	2-(4-Methylsulfonylphenyl)-N-(3-thiophen-2-ylpropyl)-6-(trifluoromethyl)pyrimidin-4-amine	Investigative	76315140	C19H18F3N3O2S2	441.5	CS(=O)(=O)C1=CC=C(C=C1)C2=NC(=CC(=N2)NCCCC3=CC=CS3)C(F)(F)F	IC50 = 826456.5 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B91HQM	5-Chloro-3-(4-chlorophenyl)-2-(4-methylsulfonylphenyl)pyran-4-one	Investigative	44309825	C18H12Cl2O4S	395.3	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)C(=CO2)Cl)C3=CC=C(C=C3)Cl	IC50 = 936052.05 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B93RBW	Sodium;2-[2-(4-methoxyphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56675535	C22H23NaO4	374.4	CC(C1=C(C=C(C=C1)CC2CCCC2=O)C3=CC=C(C=C3)OC)C(=O)[O-].[Na+]	IC50 = 430000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B9J5HW	3-(4-Methylsulfonylphenyl)-4-phenylbenzoic acid	Investigative	44384436	C20H16O4S	352.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=CC(=C2)C(=O)O)C3=CC=CC=C3	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	B9VK4M	[1-(4-Methanesulfonyl-phenyl)-2-pyridin-3-yl-1H-imidazol-4-yl]-methanol	Investigative	10830211	C16H15N3O3S	329.4	CS(=O)(=O)C1=CC=C(C=C1)N2C=C(N=C2C3=CN=CC=C3)CO	IC50 = 934000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BB78JV	2-[4-(Methylsulfonyl)phenyl]-3-(4-fluorophenyl)-5-(trifluoroacetyl)-1H-pyrrole	Investigative	10431739	C19H13F4NO3S	411.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=C(N2)C(=O)C(F)(F)F)C3=CC=C(C=C3)F	IC50 = 298200 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BDC5S7	5-Chloro-3-(4-fluorophenyl)-2-(4-methylsulfonylphenyl)pyran-4-thione	Investigative	44309745	C18H12ClFO3S2	394.9	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=S)C(=CO2)Cl)C3=CC=C(C=C3)F	IC50 = 835795.45 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BE9TN6	4,6-Dimethyl-2-[1-oxo-1-(4-phenylpiperazin-1-yl)butan-2-yl]-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	134152691	C22H26N4O2S	410.5	CCC(C(=O)N1CCN(CC1)C2=CC=CC=C2)N3C(=O)C4=C(S3)N=C(C=C4C)C	IC50 = 251188.64 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BET3Q7	3-(4-Hydroxy-phenyl)-4-(4-methanesulfonyl-phenyl)-5H-furan-2-one	Investigative	10359269	C17H14O5S	330.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=O)OC2)C3=CC=C(C=C3)O	IC50 > 250000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BF5GM3	7,8-Dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic Acid	Investigative	9818254	C11H5Cl2F3O3	313.05	C1=CC(=C(C2=C1C=C(C(O2)C(F)(F)F)C(=O)O)Cl)Cl	IC50 = 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BF78TK	2-[[2-Anilinoethyl(methyl)amino]methyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	11544686	C18H22N4OS	342.5	CC1=CC(=NC2=C1C(=O)N(S2)CN(C)CCNC3=CC=CC=C3)C	IC50 = 494300 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BG8D0L	4-(4,6-Dimethyl-3-oxo-[1,2]thiazolo[5,4-b]pyridin-2-yl)butanoic acid	Investigative	134135733	C12H14N2O3S	266.32	CC1=CC(=NC2=C1C(=O)N(S2)CCCC(=O)O)C	IC50 = 269153.48 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BHQ86P	5-Chloro-2-(4-methylsulfonylcyclohexyl)-3-(3-methylthiophen-1-ium-1-yl)pyran-4-one	Investigative	53323460	C17H20ClO4S2+	387.9	CC1=C[S+](C=C1)C2=C(OC=C(C2=O)Cl)C3CCC(CC3)S(=O)(=O)C	IC50 = 736037.6 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BJ72WC	2-(Methylthio)phenol, trifluoroacetate	Investigative	10847385	C9H7F3O2S	236.21	CSC1=CC=CC=C1OC(=O)C(F)(F)F	IC50 = 260000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BJV7O4	(2S)-2-[[(2S)-2-[[(2S)-2-[(4-Fluorobenzoyl)amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]butanedioic acid	Investigative	57393171	C27H29FN4O7S	572.6	CSCC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)C3=CC=C(C=C3)F	IC50 = 450000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BKCM19	2-[1-(4-Chlorobenzoyl)-2-phenylindol-3-yl]acetic acid	Investigative	57393522	C23H16ClNO3	389.8	C1=CC=C(C=C1)C2=C(C3=CC=CC=C3N2C(=O)C4=CC=C(C=C4)Cl)CC(=O)O	IC50 > 400000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BL2CU0	2-[3-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-oxopropyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	134143054	C22H25N3O4S	427.5	CC1=CC(=NC2=C1C(=O)N(S2)CCC(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C	IC50 = 288403.15 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BLH4M6	2-[(4,6-Dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-yl)oxy]propanoic acid	Investigative	134138298	C11H12N2O3S	252.29	CC1=CC(=NC2=C1C(=NS2)OC(C)C(=O)O)C	IC50 = 218776.16 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BLKV17	4-Methyl-N''-((4-oxo-4H-chromen-3-yl)methylene)benzenesulfonohydrazide	Investigative	9644405	C17H14N2O4S	342.4	CC1=CC=C(C=C1)S(=O)(=O)N/N=C/C2=COC3=CC=CC=C3C2=O	IC50 = 203690 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BM7BG4	[(2R,3R,4R,5R,6R)-2-[[(2S,3S)-3,4-Dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxymethyl]-6-[2-(3,4-dihydroxyphenyl)ethoxy]-5-hydroxy-4-[(2R,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl] (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate	Investigative	44429859	C34H44O19	756.7	C[C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O[C@@H]2[C@H]([C@@H](O[C@@H]([C@H]2OC(=O)/C=C/C3=CC(=C(C=C3)O)O)CO[C@@H]4[C@H](C(CO4)(CO)O)O)OCCC5=CC(=C(C=C5)O)O)O)O)O)O	IC50 = 490000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BM7LQ0	Acetic acid 2-benzylsulfanyl-phenyl ester	Investigative	9834940	C15H14O2S	258.3	CC(=O)OC1=CC=CC=C1SCC2=CC=CC=C2	IC50 = 250000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BO4DI5	(2S)-2-[[(2S)-2-[[(2S)-2-[(4-Fluorobenzoyl)amino]-3-phenylpropanoyl]amino]-4-methylsulfanylbutanoyl]amino]butanedioic acid	Investigative	57391400	C25H28FN3O7S	533.6	CSCC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=CC=C(C=C2)F	IC50 = 450000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BOA98P	3-[5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-yl]-propionic acid	Investigative	44330273	C20H17FO4S2	404.5	CS(=O)(=O)C1=CC=C(C=C1)C2=C(SC(=C2)CCC(=O)O)C3=CC=C(C=C3)F	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BOHT35	(2S)-2-[[(2S)-2-[[(2S)-2-[(4-Fluorobenzoyl)amino]-3-(4-hydroxyphenyl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]pentanedioic acid	Investigative	57400090	C26H30FN3O8S	563.6	CSCC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)C2=CC=C(C=C2)F	IC50 = 500000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BOM70P	2-[(4-Cyclohexylpiperazin-1-yl)methyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	24848656	C19H28N4OS	360.5	CC1=CC(=NC2=C1C(=O)N(S2)CN3CCN(CC3)C4CCCCC4)C	IC50 = 245470.89 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BP3OQ7	N-[3-(1-Methylpyrrol-2-yl)propyl]-2-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-4-amine	Investigative	76326065	C20H21F3N4O2S	438.5	CN1C=CC=C1CCCNC2=NC(=NC(=C2)C(F)(F)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 251258.06 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BP9F3H	5-(4''-Methanesulfonyl-biphenyl-2-yl)-pyrimidine	Investigative	44383556	C17H14N2O2S	310.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2C3=CN=CN=C3	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BPY42U	2-(4-Methylsulfonylphenyl)-6-(trifluoromethyl)-N-[[4-(trifluoromethyl)phenyl]methyl]pyrimidin-4-amine	Investigative	44456739	C20H15F6N3O2S	475.4	CS(=O)(=O)C1=CC=C(C=C1)C2=NC(=CC(=N2)NCC3=CC=C(C=C3)C(F)(F)F)C(F)(F)F	IC50 = 520834.81 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BQ8P0W	3,4-Bis-(4-methanesulfonyl-phenyl)-thiophene	Investigative	44330531	C18H16O4S3	392.5	CS(=O)(=O)C1=CC=C(C=C1)C2=CSC=C2C3=CC=C(C=C3)S(=O)(=O)C	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BQM6J4	(2S)-2-[[(2S)-2-[[(2S)-2-[(4-Fluorobenzoyl)amino]-3-(1H-indol-3-yl)propanoyl]amino]-4-methylsulfanylbutanoyl]amino]pentanedioic acid	Investigative	57400089	C28H31FN4O7S	586.6	CSCC[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CC1=CNC2=CC=CC=C21)NC(=O)C3=CC=C(C=C3)F	IC50 = 350000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BR3JF7	2-(4-Methanesulfonyl-phenyl)-3-phenyl-pyrazine	Investigative	44384383	C17H14N2O2S	310.4	CS(=O)(=O)C1=CC=C(C=C1)C2=NC=CN=C2C3=CC=CC=C3	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BR5F4S	4-[4-(Furan-2-ylmethylamino)-6-(trifluoromethyl)pyrimidin-2-yl]benzenesulfonamide	Investigative	44456716	C16H13F3N4O3S	398.4	C1=COC(=C1)CNC2=NC(=NC(=C2)C(F)(F)F)C3=CC=C(C=C3)S(=O)(=O)N	IC50 = 358426.41 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BR8Z4X	2-[1-(4-Chlorobenzoyl)-2-ethylindol-3-yl]acetic acid	Investigative	53249089	C19H16ClNO3	341.8	CCC1=C(C2=CC=CC=C2N1C(=O)C3=CC=C(C=C3)Cl)CC(=O)O	IC50 > 400000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BRCU27	N-[(3-Methylphenyl)methyl]-2-(4-methylsulfonylphenyl)-6-(trifluoromethyl)pyrimidin-4-amine	Investigative	44456798	C20H18F3N3O2S	421.4	CC1=CC(=CC=C1)CNC2=NC(=NC(=C2)C(F)(F)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 = 518143.44 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BS16FD	Sodium;2-[2-iodo-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56668663	C15H16INaO3	394.18	CC(C1=C(C=C(C=C1)CC2CCCC2=O)I)C(=O)[O-].[Na+]	IC50 = 540000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BSY6G9	2-(4''-Methanesulfonyl-biphenyl-2-yl)-pyridine	Investigative	44383449	C18H15NO2S	309.4	CS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC=C2C3=CC=CC=N3	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BTP1R2	N-Sinapoyl Serotonin	Investigative	46892801	C21H22N2O5	382.4	COC1=CC(=CC(=C1O)OC)/C=C/C(=O)NCCC2=CNC3=C2C=C(C=C3)O	IC50 > 400000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BU2XW4	2-[2-[4-(3-Chlorophenyl)piperazin-1-yl]-2-oxoethyl]-4,6-dimethyl-[1,2]thiazolo[5,4-b]pyridin-3-one	Investigative	20876816	C20H21ClN4O2S	416.9	CC1=CC(=NC2=C1C(=O)N(S2)CC(=O)N3CCN(CC3)C4=CC(=CC=C4)Cl)C	IC50 = 407380.28 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BULG50	2-Acetoxyphenyl methyl sulfide	Investigative	470258	C9H10O2S	182.24	CC(=O)OC1=CC=CC=C1SC	IC50 = 250000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BV4EF1	2-Methylthiophenyl chloroacetate	Investigative	10536723	C9H9ClO2S	216.68	CSC1=CC=CC=C1OC(=O)CCl	IC50 = 360000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BVD6P0	Trp-Tyr-Asp	Investigative	57398427	C24H26N4O7	482.5	C1=CC=C2C(=C1)C(=CN2)C[C@@H](C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](CC(=O)O)C(=O)O)N	IC50 = 700000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BVI13H	2-(4-Methanesulfonyl-phenyl)-3-phenyl-pyridine	Investigative	44384384	C18H15NO2S	309.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=CC=N2)C3=CC=CC=C3	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BVQ8X4	2-Hydroxy-5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzoic Acid	Investigative	11637444	C15H12O4	256.25	C1=CC(=CC=C1/C=C/C2=CC(=C(C=C2)O)C(=O)O)O	IC50 > 500000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BVR52F	4-(4-Methylsulfonylphenyl)-3-phenylaniline	Investigative	44384325	C19H17NO2S	323.4	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C=C(C=C2)N)C3=CC=CC=C3	IC50 = 254000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BY2T9H	2-[4-(Methylsulfonyl)phenyl]-3-(4-fluorophenyl)-4,5-diiodo-1H-pyrrole	Investigative	10076665	C17H12FI2NO2S	567.2	CS(=O)(=O)C1=CC=C(C=C1)C2=C(C(=C(N2)I)I)C3=CC=C(C=C3)F	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BY9I6F	Sodium;2-[3-(4-methylphenyl)-4-[(2-oxocyclopentyl)methyl]phenyl]propanoate	Investigative	56665212	C22H23NaO3	358.4	CC1=CC=C(C=C1)C2=C(C=CC(=C2)C(C)C(=O)[O-])CC3CCCC3=O.[Na+]	IC50 = 420000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BZ0J2R	(2E,5E)-5-[(3-Chlorophenyl)methylidene]-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-one	Investigative	135783304	C13H8ClN3OS2	321.8	C1=CC(=CC(=C1)Cl)/C=C/2\\C(=O)N/C(=N\\C3=NC=CS3)/S2	IC50 = 262000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BZ7P4R	N-(5-Aminopyridin-2-yl)-4-(trifluoromethyl)benzamide	Investigative	24752865	C13H10F3N3O	281.23	C1=CC(=CC=C1C(=O)NC2=NC=C(C=C2)N)C(F)(F)F	IC50 = 210000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BZ8K2P	(E)-3-[5-(4-Fluoro-phenyl)-4-(4-methanesulfonyl-phenyl)-thiophen-2-yl]-acrylic acid ethyl ester	Investigative	44330483	C22H19FO4S2	430.5	CCOC(=O)/C=C/C1=CC(=C(S1)C2=CC=C(C=C2)F)C3=CC=C(C=C3)S(=O)(=O)C	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	BZQ29K	1-Methyl-4-[2-(4-methylsulfonylphenyl)phenyl]-3,6-dihydro-2H-pyridine	Investigative	15485951	C19H21NO2S	327.4	CN1CCC(=CC1)C2=CC=CC=C2C3=CC=C(C=C3)S(=O)(=O)C	IC50 > 300000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	D0F6CD	SEROTONIN	Investigative	5202	C10H12N2O	176.21	C1=CC2=C(C=C1O)C(=CN2)CCN	IC50 > 400000 nM	Non binder
T66665	Prostaglandin G/H synthase 2	D0PJ3M	cinnamaldehyde	Investigative	637511	C9H8O	132.16	C1=CC=C(C=C1)/C=C/C=O	IC50 = 245000 nM	Non binder