TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T68163	Tyrosine-protein kinase Lyn	D00OWF	HARMINE	Patented	5280953	C13H12N2O	212.25	CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC	IC50 > 250000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	B7YH1Q	1-(5-Methyl-1H-imidazol-4-yl)-9H-beta-carboline	Investigative	44269518	C15H12N4	248.28	CC1=C(N=CN1)C2=NC=CC3=C2NC4=CC=CC=C34	IC50 > 250000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	BC8V9Z	N-(1-(3-Amino-3-oxopropyl)-5-(N-ethylcyclohexanecarboxamido)-1H-benzo[d]imidazol-2-yl)-4-cyanobenzamide	Investigative	44589021	C27H30N6O3	486.6	CCN(C1=CC2=C(C=C1)N(C(=N2)NC(=O)C3=CC=C(C=C3)C#N)CCC(=O)N)C(=O)C4CCCCC4	IC50 > 1000000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	BP3RT8	N-(1-(3-(1H-Imidazol-1-yl)propyl)-5-(N-methylcyclohexanecarboxamido)-1H-benzo[d]imidazol-2-yl)-4-cyanobenzamide	Investigative	25191024	C29H31N7O2	509.6	CN(C1=CC2=C(C=C1)N(C(=N2)NC(=O)C3=CC=C(C=C3)C#N)CCCN4C=CN=C4)C(=O)C5CCCCC5	IC50 > 1000000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	BRGW80	N-(1-(3-Amino-3-oxopropyl)-5-(N-methylcyclohexanecarboxamido)-1H-benzo[d]imidazol-2-yl)-4-chlorobenzamide	Investigative	25110796	C25H28ClN5O3	482	CN(C1=CC2=C(C=C1)N(C(=N2)NC(=O)C3=CC=C(C=C3)Cl)CCC(=O)N)C(=O)C4CCCCC4	IC50 > 1000000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	BY6BL7	1-(2-Chloro-5-nitro-phenyl)-9H-beta-carboline	Investigative	44269404	C17H10ClN3O2	323.7	C1=CC=C2C(=C1)C3=C(N2)C(=NC=C3)C4=C(C=CC(=C4)[N+](=O)[O-])Cl	IC50 > 250000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	BZ0MU1	7-Fluoro-1-methyl-9H-pyrido[3,4-b]indole	Investigative	44269392	C12H9FN2	200.21	CC1=NC=CC2=C1NC3=C2C=CC(=C3)F	IC50 > 250000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	D01IZN	Y-c[D-Pen-(2')Nal-GSFC]KR-NH2	Investigative	44312289	C49H69N13O10S2	1064.3	CC(=O)N[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](CSSC1(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)CC2=CC=CC=C2)CO)CC3=CC4=CC=CC=C4C=C3	IC50 > 800000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	D02SRA	Y-c[D-Pen-D-(2')Nal-GSFC]KR-NH2	Investigative	44312288	C49H69N13O10S2	1064.3	CC(=O)N[C@H]1C(=O)N[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](CSSC1(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)CC2=CC=CC=C2)CO)CC3=CC4=CC=CC=C4C=C3	IC50 > 800000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	D07ERV	Y-c[D-Pen-(3,5-diI)Tyr-GSFC]KR-NH2	Investigative	44312580	C52H72I2N14O12S2	1403.2	CC1([C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](CSS1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)CC2=CC=CC=C2)CO)CC3=CC(=C(C(=C3)I)O)I)NC(=O)[C@H](CC4=CC=C(C=C4)O)N)C	IC50 > 800000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	D09DVB	Y-c[D-Pen-(2R,3R)-2-Me-(2')Nal-GSFC]KR-NH2	Investigative	44312287	C57H78N14O11S2	1199.5	C[C@H]([C@@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](CSSC([C@H](C(=O)N1)NC(=O)[C@H](CC2=CC=C(C=C2)O)N)(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)CC3=CC=CC=C3)CO)C4=CC5=CC=CC=C5C=C4	IC50 > 800000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	D0A2LX	Y-c[D-Pen-(3-I)Tyr-GSFC]KR-NH2	Investigative	44312363	C52H73IN14O12S2	1277.3	CC1([C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](CSS1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)CC2=CC=CC=C2)CO)CC3=CC(=C(C=C3)O)I)NC(=O)[C@H](CC4=CC=C(C=C4)O)N)C	IC50 > 800000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	D0B4PI	Y-c[D-Pen-(2R,3S)-2-Me-(2')Nal-GSFC]KR-NH2	Investigative	44312309	C57H78N14O11S2	1199.5	C[C@@H]([C@@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](CSSC([C@H](C(=O)N1)NC(=O)[C@H](CC2=CC=C(C=C2)O)N)(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)CC3=CC=CC=C3)CO)C4=CC5=CC=CC=C5C=C4	IC50 > 800000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	D0Q2UZ	Y-c[D-Pen-(2S,3R)-2-Me-(2')Nal-GSFC]KR-NH2	Investigative	44312307	C57H78N14O11S2	1199.5	C[C@H]([C@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](CSSC([C@H](C(=O)N1)NC(=O)[C@H](CC2=CC=C(C=C2)O)N)(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)CC3=CC=CC=C3)CO)C4=CC5=CC=CC=C5C=C4	IC50 > 800000 nM	Non binder
T68163	Tyrosine-protein kinase Lyn	D0W7LW	Y-c[D-Pen-(2S,3S)-2-Me-(2')Nal-GSFC]KR-NH2	Investigative	44312308	C57H78N14O11S2	1199.5	C[C@@H]([C@H]1C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](CSSC([C@H](C(=O)N1)NC(=O)[C@H](CC2=CC=C(C=C2)O)N)(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)CC3=CC=CC=C3)CO)C4=CC5=CC=CC=C5C=C4	IC50 > 800000 nM	Non binder