TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T75570 Yes tyrosine kinase B1F0LD (4-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenoxy)-acetic acid Investigative 44314380 C28H37N2O9P 576.6 CC(C)(C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)CCC3=CC(=C(C=C3)OCC(=O)O)P(=O)(O)O IC50 = 303000 nM Non binder T75570 Yes tyrosine kinase B5FD4Y (5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-hydroxy-phenyl)-phosphonic acid Investigative 44314402 C26H35N2O7P 518.5 CC(C)(C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)CCC3=CC(=C(C=C3)O)P(=O)(O)O IC50 > 500000 nM Non binder T75570 Yes tyrosine kinase BEYC70 [5-{2-[1-(3-Carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-(tetrazol-1-ylmethoxy)-phenyl]-phosphonic acid Investigative 44313990 C28H37N6O7P 600.6 CC(C)(C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)CCC3=CC(=C(C=C3)OCN4C=NN=N4)P(=O)(O)O IC50 > 500000 nM Non binder T75570 Yes tyrosine kinase BN14WA {4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmethoxy-benzylcarbamoyl)-ethyl]-2-phosphono-phenoxy}-acetic acid Investigative 44313930 C28H36N3O10P 605.6 CC(=O)NC(CC1=CC(=C(C=C1)OCC(=O)O)P(=O)(O)O)C(=O)NCC2=CC(=C(C=C2)OCC3CCCCC3)C(=O)N IC50 > 500000 nM Non binder T75570 Yes tyrosine kinase BR0A8S Trifluoro-methanesulfonic acid 4-{2-[1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-1-methyl-ethylcarbamoyl]-ethyl}-2-phosphono-phenyl ester Investigative 44313929 C27H34F3N2O9PS 650.6 CC(C)(C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)CCC3=CC(=C(C=C3)OS(=O)(=O)C(F)(F)F)P(=O)(O)O IC50 > 500000 nM Non binder T75570 Yes tyrosine kinase BTP30D (4-{2-Acetylamino-2-[(S)-1-(3-carbamoyl-4-cyclohexylmethoxy-phenyl)-ethylcarbamoyl]-ethyl}-phenoxy)-acetic acid Investigative 44314372 C29H37N3O7 539.6 C[C@@H](C1=CC(=C(C=C1)OCC2CCCCC2)C(=O)N)NC(=O)C(CC3=CC=C(C=C3)OCC(=O)O)NC(=O)C IC50 > 500000 nM Non binder T75570 Yes tyrosine kinase BWAR36 {4-[2-Acetylamino-2-(3-carbamoyl-4-cyclohexylmethoxy-phenylcarbamoyl)-ethyl]-2-phosphono-phenoxy}-acetic acid Investigative 44314373 C27H34N3O10P 591.5 CC(=O)NC(CC1=CC(=C(C=C1)OCC(=O)O)P(=O)(O)O)C(=O)NC2=CC(=C(C=C2)OCC3CCCCC3)C(=O)N IC50 > 500000 nM Non binder