TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T79570	Aggrecanase-1	B48ZMI	N-[(2s,4s)-1-({4-[2-(3,5-Dimethyl-1,2-Oxazol-4-Yl)ethyl]piperidin-1-Yl}sulfonyl)-4-(5-Fluoropyrimidin-2-Yl)-2-Methylpentan-2-Yl]-N-Hydroxyformamide	Investigative	50990921	C23H34FN5O5S	511.6	CC1=C(C(=NO1)C)CCC2CCN(CC2)S(=O)(=O)C[C@](C)(C[C@H](C)C3=NC=C(C=N3)F)N(C=O)O	IC50 = 25118864.32 nM	Non binder
T79570	Aggrecanase-1	B5IT3U	(2R)-2-[[4-[3-(Acetamidomethyl)phenyl]phenyl]sulfonylamino]-3-methylbutanoic acid	Investigative	57392020	C20H24N2O5S	404.5	CC(C)[C@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=CC(=C2)CNC(=O)C	IC50 > 200000 nM	Non binder
T79570	Aggrecanase-1	BF38QU	(2R)-2-[[4-[4-[[Acetyl(methyl)amino]methyl]phenyl]phenyl]sulfonylamino]-3-methylbutanoic acid	Investigative	57393743	C21H26N2O5S	418.5	CC(C)[C@H](C(=O)O)NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(C=C2)CN(C)C(=O)C	IC50 > 200000 nM	Non binder