TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T86052	Telomerase reverse transcriptase	D09YDM	Camptothecin	Phase 3	24360	C20H16N2O4	348.4	CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O	IC50 > 300000 nM	Non binder
T86052	Telomerase reverse transcriptase	B0HTO5	3-N-(2-Amino-1,6-dimethylpyrimidin-1-ium-4-yl)-5-methyl-6-(4-methylphenyl)phenanthridin-5-ium-3,8-diamine	Investigative	46898227	C27H28N6+2	436.6	CC1=CC=C(C=C1)C2=C3C=C(C=CC3=C4C=CC(=CC4=[N+]2C)NC5=NC(=[N+](C(=C5)C)C)N)N	IC50 = 46773514.13 nM	Non binder
T86052	Telomerase reverse transcriptase	B1AF4H	Isometamidium	Investigative	72452	C28H26N7+	460.6	CC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)N=NNC5=CC=CC(=C5)C(=N)N)N	IC50 = 19054607.18 nM	Non binder
T86052	Telomerase reverse transcriptase	B4XJ6S	Collinomycin	Investigative	5378308	C27H20O12	536.4	COC1=CC(=C(C2=C1C(=O)C3=C(C2=O)OC(=C3)CCC4=C(C(=C5C(=C4)C=C(OC5=O)C(=O)OC)O)O)O)OC	IC50 > 200000 nM	Non binder
T86052	Telomerase reverse transcriptase	B91HFT	3-[(3,8-Diamino-5-ethyl-6-phenylphenanthridin-5-ium-7-yl)diazenyl]benzenecarboximidamide	Investigative	10145782	C28H26N7+	460.6	CC[N+]1=C2C=C(C=CC2=C3C=CC(=C(C3=C1C4=CC=CC=C4)N=NC5=CC=CC(=C5)C(=N)N)N)N	IC50 = 97723722.1 nM	Non binder
T86052	Telomerase reverse transcriptase	BDXM10	3,11-Difluoro-6,8,13-trimethyl-8H-quino[4,3,2-KL]acridin-13-ium	Investigative	5288693	C22H17F2N2+	347.4	CC1=CC2=C3C(=C1)N(C4=C(C3=[N+](C5=C2C=C(C=C5)F)C)C=C(C=C4)F)C	IC50 = 331131121.5 nM	Non binder
T86052	Telomerase reverse transcriptase	BO1Y5B	Altertoxin I	Investigative	104860	C20H16O6	352.3	C1C[C@]2([C@@H]3[C@H](CC(=O)C4=C(C=CC(=C34)C5=C2C(=C(C=C5)O)C1=O)O)O)O	IC50 > 1000000 nM	Non binder
T86052	Telomerase reverse transcriptase	BR0L7N	3-Amino-8-(4-amidinophenylazoamino)-6-phenyl-5-ethylphenanthridine-5-ium	Investigative	199438	C28H26N7+	460.6	CC[N+]1=C2C=C(C=CC2=C3C=CC(=CC3=C1C4=CC=CC=C4)NN=NC5=CC=C(C=C5)C(=N)N)N	IC50 = 18197008.59 nM	Non binder
T86052	Telomerase reverse transcriptase	BS53ML	3-[(E)-4-Hydroxybenzylidene]-6-hydroxybenzofuran-2(3H)-one	Investigative	9837937	C15H10O4	254.24	C1=CC(=CC=C1/C=C/2\\C3=C(C=C(C=C3)O)OC2=O)O	IC50 > 400000 nM	Non binder
T86052	Telomerase reverse transcriptase	D0L8BN	TOPOSTATIN	Investigative	44559995	C36H58N4O11S	754.9	CCCCCCCC(C)C/C=C(\\C)/C=C/C(=O)C(C)CCC1C(C(=O)NC(=C)C(=O)NC[C@@H](C(=O)N[C@H](C(=O)O1)CC(C(=O)N)OS(=O)(=O)O)C)C	IC50 > 250000 nM	Non binder