TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T88240 Bacterial Dihydropteroate synthetase B0UT3H 2-Amino-5-formyl-6-(methylamino)pyrimidin-4(3H)-one Investigative 135987608 C6H8N4O2 168.15 CNC1=C(C(=O)NC(=N1)N)C=O IC50 = 300000 nM Non binder T88240 Bacterial Dihydropteroate synthetase B1V4NB 2-Amino-5-nitroso-4-(propan-2-ylamino)-1H-pyrimidin-6-one Investigative 135987607 C7H11N5O2 197.19 CC(C)NC1=C(C(=O)NC(=N1)N)N=O IC50 = 208000 nM Non binder T88240 Bacterial Dihydropteroate synthetase BRK51I 2-Amino-6-oxo-4-(4-phenylbutylamino)-1H-pyrimidine-5-carbonitrile Investigative 135604870 C15H17N5O 283.33 C1=CC=C(C=C1)CCCCNC2=C(C(=O)NC(=N2)N)C#N IC50 = 290000 nM Non binder T88240 Bacterial Dihydropteroate synthetase BT0GU9 Isocytosine Investigative 66950 C4H5N3O 111.1 C1=CN=C(NC1=O)N IC50 = 500000 nM Non binder