TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T94400	Mycobacterium Thymidine monophosphate kinase	D03KXY	Doxifluridine	Approved	18343	C9H11FN2O5	246.19	C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=O)NC2=O)F)O)O	Ki = 560000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	B1XKJ4	Ethyl 3-[4-[(5-methyl-2,4-dioxopyrimidin-1-yl)methyl]phenyl]propanoate	Investigative	5276671	C17H20N2O4	316.35	CCOC(=O)CCC1=CC=C(C=C1)CN2C=C(C(=O)NC2=O)C	Ki = 265000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	B1Y3CU	[(2R,3S,5R)-5-[2,4-Dioxo-5-(2-thienyl)pyrimidin-1-yl]-3-hydroxy-tetrahydrofuran-2-yl]methyl dihydrogen phosphate	Investigative	502269	C13H15N2O8PS	390.31	C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C3=CC=CS3)COP(=O)(O)O)O	Ki = 270000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	B3DW6A	2-[(2R,3S,5R)-3-Hydroxy-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)tetrahydrofuran-2-yl]-N-methyl-ethanesulfonamide	Investigative	71508267	C12H19N3O6S	333.36	CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CCS(=O)(=O)NC)O	Ki = 240000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	B4B3NS	[(2S,3S,4R,5R)-3-(Aminomethyl)-4-hydroxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methyl dihydrogen phosphate	Investigative	3006432	C11H18N3O8P	351.25	CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)O)CN)O	Ki = 315000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	B4DYO8	1-((2R,5S)-4-Azido-3-hydroxy-5-iodomethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione	Investigative	510574	C10H12IN5O4	393.14	CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CI)N=[N+]=[N-])O	Ki = 490000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	B5V6QF	1-[2-[(5-Methyl-2,4-dioxo-pyrimidin-1-yl)methoxy]ethyl]-3-phenyl-thiourea	Investigative	23636348	C15H18N4O3S	334.4	CC1=CN(C(=O)NC1=O)COCCNC(=S)NC2=CC=CC=C2	Ki = 260000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	B64EZX	3'-Deoxy-3'-aminothymidine monophosphate	Investigative	162501	C10H16N3O7P	321.22	CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COP(=O)(O)O)N	Ki = 235000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	B9OEN2	1-[(2R,4S,5R)-4-Hydroxy-5-(2-methylsulfonylethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione	Investigative	71508217	C12H18N2O6S	318.35	CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CCS(=O)(=O)C)O	Ki = 340000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BC9TH4	1-Benzyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbonitrile	Investigative	2823137	C12H9N3O2	227.22	C1=CC=C(C=C1)CN2C=C(C(=O)NC2=O)C#N	Ki = 980000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BCR6X2	3'-Amino-3'-deoxythymidine	Investigative	108074	C10H15N3O4	241.24	CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)N	Ki = 230000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BDM85C	5-Methyl-7-Propyl-1,6-Naphthyridin-2(1h)-One	Investigative	19093772	C12H14N2O	202.25	CCCC1=CC2=C(C=CC(=O)N2)C(=N1)C	IC50 = 590000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BG2S0Q	1-((2R,5R)-4-Amino-3-hydroxy-5-methyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione	Investigative	510575	C10H15N3O4	241.24	C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=C(C(=O)NC2=O)C)O)N	Ki = 1900000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BGI52E	5-Methyl-2-oxo-1H-1,6-naphthyridine-3-carbonitrile	Investigative	5713068	C10H7N3O	185.18	CC1=NC=CC2=C1C=C(C(=O)N2)C#N	IC50 = 634000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BJ0VH2	4-[4-[(2,4-Dioxopyrimidin-1-yl)methyl]phenyl]butanoic acid	Investigative	16726539	C15H16N2O4	288.3	C1=CC(=CC=C1CCCC(=O)O)CN2C=CC(=O)NC2=O	Ki = 202000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BJ3EZ0	1-[(2R,3R,4R,5S)-4-(Aminomethyl)-3-chloro-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione	Investigative	5273624	C11H16ClN3O4	289.71	CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)CN)Cl	Ki = 390000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BJS65D	Spongothymidine	Investigative	65049	C10H14N2O6	258.23	CC1=CN(C(=O)NC1=O)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O	Ki = 238000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BK1TM7	Edoxudine	Investigative	66377	C11H16N2O5	256.25	CCC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CO)O	Ki = 1140000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BP1W8Y	1-[(3-Chlorophenyl)methyl]-2,4-dioxo-pyrimidine-5-carbonitrile	Investigative	2823141	C12H8ClN3O2	261.66	C1=CC(=CC(=C1)Cl)CN2C=C(C(=O)NC2=O)C#N	Ki = 810000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BP58GV	1-(4-Aminomethyl-3-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione	Investigative	508216	C11H17N3O5	271.27	CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)CN)O	Ki = 393000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BQ4PJ7	1-(4-Azidomethyl-3-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione	Investigative	477014	C11H15N5O5	297.27	CC1=CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)CN=[N+]=[N-])O	Ki = 770000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	BWSY31	1-[(2R,4S,5R)-5-[[4-(4-Chlorophenyl)triazol-1-yl]methyl]-4-hydroxy-tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione	Investigative	57395804	C18H18ClN5O4	403.8	CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)CN3C=C(N=N3)C4=CC=C(C=C4)Cl)O	Ki = 201000 nM	Non binder
T94400	Mycobacterium Thymidine monophosphate kinase	D0X1ZP	5-fluorouridine	Investigative	9427	C9H11FN2O6	262.19	C1=C(C(=O)NC(=O)N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)F	Ki = 521000 nM	Non binder