TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T97141	Myosin light kinase	B08ODT	Ethyl 4-(4-chlorophenyl)-3-[2-(4-chlorophenyl)-2-oxoethyl]-2-methoxy-6-methyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225475	C23H24Cl2N2O4	463.3	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)Cl)CC(=O)C3=CC=C(C=C3)Cl)OC)C	IC50 = 2421307.79 nM	Non binder
T97141	Myosin light kinase	B09JWM	Ethyl 3-[2-(4-chlorophenyl)-2-oxoethyl]-4-(4-hydroxyphenyl)-2-methoxy-6-methyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225478	C23H25ClN2O5	444.9	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)O)CC(=O)C3=CC=C(C=C3)Cl)OC)C	IC50 = 6579001.72 nM	Non binder
T97141	Myosin light kinase	B0SH4R	1-[4-(4-Chlorophenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]propan-1-one	Investigative	122190928	C20H17ClN2OS	368.9	CCC(=O)C1=C(N=C2N(C1C3=CC=C(C=C3)Cl)C4=CC=CC=C4S2)C	IC50 = 9009070.8 nM	Non binder
T97141	Myosin light kinase	B2A7YL	1-[2-Methyl-4-(4-chlorophenyl)-4H-pyrimido[2,1-b]benzothiazole-3-yl]ethanone	Investigative	101899357	C19H15ClN2OS	354.9	CC1=C(C(N2C3=CC=CC=C3SC2=N1)C4=CC=C(C=C4)Cl)C(=O)C	IC50 = 10989046.22 nM	Non binder
T97141	Myosin light kinase	B2ZG4U	1-[4-(4-Hydroxy-3-methoxyphenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]ethanone	Investigative	122190926	C20H18N2O3S	366.4	CC1=C(C(N2C3=CC=CC=C3SC2=N1)C4=CC(=C(C=C4)O)OC)C(=O)C	IC50 = 27248336.88 nM	Non binder
T97141	Myosin light kinase	B39BIZ	Ethyl 4-(4-hydroxyphenyl)-2-methoxy-6-methyl-3-phenacyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225477	C23H26N2O5	410.5	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)O)CC(=O)C3=CC=CC=C3)OC)C	IC50 = 9803925.45 nM	Non binder
T97141	Myosin light kinase	B4V1AP	1-[4-(4-Methoxyphenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]propan-1-one	Investigative	122190932	C21H20N2O2S	364.5	CCC(=O)C1=C(N=C2N(C1C3=CC=C(C=C3)OC)C4=CC=CC=C4S2)C	IC50 = 46083982.18 nM	Non binder
T97141	Myosin light kinase	B5UL0Z	Ethyl 3-[2-(4-chlorophenyl)-2-oxoethyl]-2-methoxy-4-(4-methoxyphenyl)-6-methyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225476	C24H27ClN2O5	458.9	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)OC)CC(=O)C3=CC=C(C=C3)Cl)OC)C	IC50 = 3300350.01 nM	Non binder
T97141	Myosin light kinase	B5Y8WU	1-[4-(4-Hydroxyphenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]propan-1-one	Investigative	122190931	C20H18N2O2S	350.4	CCC(=O)C1=C(N=C2N(C1C3=CC=C(C=C3)O)C4=CC=CC=C4S2)C	IC50 = 16949231.05 nM	Non binder
T97141	Myosin light kinase	B68HQZ	1-[4-(4-Hydroxyphenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]ethanone	Investigative	122190921	C19H16N2O2S	336.4	CC1=C(C(N2C3=CC=CC=C3SC2=N1)C4=CC=C(C=C4)O)C(=O)C	IC50 = 23753083.75 nM	Non binder
T97141	Myosin light kinase	B7AF9V	1-[2-Methyl-4-(4-nitrophenyl)-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]propan-1-one	Investigative	122190934	C20H17N3O3S	379.4	CCC(=O)C1=C(N=C2N(C1C3=CC=C(C=C3)[N+](=O)[O-])C4=CC=CC=C4S2)C	IC50 = 32895008.28 nM	Non binder
T97141	Myosin light kinase	B7MP3U	1-[2-Methyl-4-(4-nitrophenyl)-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]ethanone	Investigative	122190924	C19H15N3O3S	365.4	CC1=C(C(N2C3=CC=CC=C3SC2=N1)C4=CC=C(C=C4)[N+](=O)[O-])C(=O)C	IC50 = 49023013.01 nM	Non binder
T97141	Myosin light kinase	B8KLT9	1-[4-[4-(Dimethylamino)phenyl]-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]ethanone	Investigative	122190925	C21H21N3OS	363.5	CC1=C(C(N2C3=CC=CC=C3SC2=N1)C4=CC=C(C=C4)N(C)C)C(=O)C	IC50 = 22883370.91 nM	Non binder
T97141	Myosin light kinase	B92RVF	Ethyl 2-methoxy-6-methyl-3-phenacyl-4-phenyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225231	C23H26N2O4	394.5	CCOC(=O)C1=C(NC(N(C1C2=CC=CC=C2)CC(=O)C3=CC=CC=C3)OC)C	IC50 = 4291904.01 nM	Non binder
T97141	Myosin light kinase	B9H1BM	Ethyl 3-[2-(4-chlorophenyl)-2-oxoethyl]-2-methoxy-6-methyl-4-phenyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225232	C23H25ClN2O4	428.9	CCOC(=O)C1=C(NC(N(C1C2=CC=CC=C2)CC(=O)C3=CC=C(C=C3)Cl)OC)C	IC50 = 3003032.28 nM	Non binder
T97141	Myosin light kinase	B9HW8T	1-[4-[4-(Dimethylamino)phenyl]-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]propan-1-one	Investigative	122190935	C22H23N3OS	377.5	CCC(=O)C1=C(N=C2N(C1C3=CC=C(C=C3)N(C)C)C4=CC=CC=C4S2)C	IC50 = 13568754.97 nM	Non binder
T97141	Myosin light kinase	B9ZIL0	1-[4-(4-Fluorophenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]ethanone	Investigative	122190919	C19H15FN2OS	338.4	CC1=C(C(N2C3=CC=CC=C3SC2=N1)C4=CC=C(C=C4)F)C(=O)C	IC50 = 13698720.35 nM	Non binder
T97141	Myosin light kinase	BAG89O	1-[4-(2-Chlorophenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]propan-1-one	Investigative	122190927	C20H17ClN2OS	368.9	CCC(=O)C1=C(N=C2N(C1C3=CC=CC=C3Cl)C4=CC=CC=C4S2)C	IC50 = 9259339.33 nM	Non binder
T97141	Myosin light kinase	BD6P0W	1-[4-(2-Chlorophenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]ethanone	Investigative	122190866	C19H15ClN2OS	354.9	CC1=C(C(N2C3=CC=CC=C3SC2=N1)C4=CC=CC=C4Cl)C(=O)C	IC50 = 10204224.39 nM	Non binder
T97141	Myosin light kinase	BDM79V	Ethyl 2-methoxy-4-(4-methoxyphenyl)-6-methyl-3-phenacyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225714	C24H28N2O5	424.5	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)OC)CC(=O)C3=CC=CC=C3)OC)C	IC50 = 13513567.02 nM	Non binder
T97141	Myosin light kinase	BDN79F	Ethyl 2-methoxy-4-(4-methoxyphenyl)-3-[2-(4-methoxyphenyl)-2-oxoethyl]-6-methyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225715	C25H30N2O6	454.5	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)OC)CC(=O)C3=CC=C(C=C3)OC)OC)C	IC50 = 24390460.5 nM	Non binder
T97141	Myosin light kinase	BEAX37	1-[4-(2-Hydroxyphenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]propan-1-one	Investigative	122190930	C20H18N2O2S	350.4	CCC(=O)C1=C(N=C2N(C1C3=CC=CC=C3O)C4=CC=CC=C4S2)C	IC50 = 21276980.72 nM	Non binder
T97141	Myosin light kinase	BF4OW2	1-[4-(4-Fluorophenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]propan-1-one	Investigative	122190929	C20H17FN2OS	352.4	CCC(=O)C1=C(N=C2N(C1C3=CC=C(C=C3)F)C4=CC=CC=C4S2)C	IC50 = 7518825.4 nM	Non binder
T97141	Myosin light kinase	BH3OR9	1-[4-(4-Hydroxy-3-methoxyphenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]propan-1-one	Investigative	122190936	C21H20N2O3S	380.5	CCC(=O)C1=C(N=C2N(C1C3=CC(=C(C=C3)O)OC)C4=CC=CC=C4S2)C	IC50 = 27248336.88 nM	Non binder
T97141	Myosin light kinase	BIE24Q	1-[4-(4-Methoxyphenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]ethanone	Investigative	122190922	C20H18N2O2S	350.4	CC1=C(C(N2C3=CC=CC=C3SC2=N1)C4=CC=C(C=C4)OC)C(=O)C	IC50 = 46729377.97 nM	Non binder
T97141	Myosin light kinase	BK59NC	Ethyl 2-methoxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-6-methyl-4-(4-methylphenyl)-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225713	C25H30N2O5	438.5	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)C)CC(=O)C3=CC=C(C=C3)OC)OC)C	IC50 = 19607851.09 nM	Non binder
T97141	Myosin light kinase	BK7FB8	Ethyl 2-methoxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-6-methyl-4-phenyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225473	C24H28N2O5	424.5	CCOC(=O)C1=C(NC(N(C1C2=CC=CC=C2)CC(=O)C3=CC=C(C=C3)OC)OC)C	IC50 = 7518825.4 nM	Non binder
T97141	Myosin light kinase	BL6KA3	Ethyl 2-methoxy-6-methyl-4-(4-methylphenyl)-3-phenacyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225711	C24H28N2O4	408.5	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)C)CC(=O)C3=CC=CC=C3)OC)C	IC50 = 5208348.07 nM	Non binder
T97141	Myosin light kinase	BNDX38	1-[4-(2-Hydroxyphenyl)-2-methyl-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]ethanone	Investigative	122190920	C19H16N2O2S	336.4	CC1=C(C(N2C3=CC=CC=C3SC2=N1)C4=CC=CC=C4O)C(=O)C	IC50 = 23256266.74 nM	Non binder
T97141	Myosin light kinase	BNJR13	Melk-TI	Investigative	73442760	C21H22N4O2	362.4	COC1=C(C=CC(=C1)C2=CNN=C2)C(=O)NC3=CC4=C(CCNCC4)C=C3	IC50 = 1000000 nM	Non binder
T97141	Myosin light kinase	BQB9L6	Ethyl 4-(4-chlorophenyl)-2-methoxy-6-methyl-3-phenacyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225474	C23H25ClN2O4	428.9	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)Cl)CC(=O)C3=CC=CC=C3)OC)C	IC50 = 3194920.09 nM	Non binder
T97141	Myosin light kinase	BV80JY	1-[2-Methyl-4-(3-nitrophenyl)-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]ethanone	Investigative	122190923	C19H15N3O3S	365.4	CC1=C(C(N2C3=CC=CC=C3SC2=N1)C4=CC(=CC=C4)[N+](=O)[O-])C(=O)C	IC50 = 49019626.74 nM	Non binder
T97141	Myosin light kinase	BW02SH	Ethyl 3-[2-(4-chlorophenyl)-2-oxoethyl]-2-methoxy-6-methyl-4-(4-methylphenyl)-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225712	C24H27ClN2O4	442.9	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)C)CC(=O)C3=CC=C(C=C3)Cl)OC)C	IC50 = 3424680.02 nM	Non binder
T97141	Myosin light kinase	BW92XI	Ethyl 4-(4-hydroxyphenyl)-2-methoxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-6-methyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	44225710	C24H28N2O6	440.5	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)O)CC(=O)C3=CC=C(C=C3)OC)OC)C	IC50 = 10204224.39 nM	Non binder
T97141	Myosin light kinase	BYDN36	1-[2-Methyl-4-(3-nitrophenyl)-4H-pyrimido[2,1-b][1,3]benzothiazol-3-yl]propan-1-one	Investigative	122190933	C20H17N3O3S	379.4	CCC(=O)C1=C(N=C2N(C1C3=CC(=CC=C3)[N+](=O)[O-])C4=CC=CC=C4S2)C	IC50 = 47620066.77 nM	Non binder
T97141	Myosin light kinase	BZ90TS	Ethyl 4-(4-chlorophenyl)-2-methoxy-3-[2-(4-methoxyphenyl)-2-oxoethyl]-6-methyl-2,4-dihydro-1H-pyrimidine-5-carboxylate	Investigative	122190865	C24H27ClN2O5	458.9	CCOC(=O)C1=C(NC(N(C1C2=CC=C(C=C2)Cl)CC(=O)C3=CC=C(C=C3)OC)OC)C	IC50 = 5494523.05 nM	Non binder