TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T98945	HUMAN dibasic-processing enzyme	B05QYE	Benzoylamino-guanidine	Investigative	262935	C8H10N4O	178.19	C1=CC=C(C=C1)C(=O)NN=C(N)N	Ki = 376000 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	B27QWD	2-(1-Phenylethylidene)hydrazinecarboximidamide	Investigative	5916478	C9H12N4	176.22	C/C(=N\\N=C(N)N)/C1=CC=CC=C1	Ki = 273000 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	B2DHO6	N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(4-guanidino-phenoxy)-cyclohexyl]-guanidine	Investigative	44593148	C22H32N12O2	496.6	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC2=CC=C(C=C2)N=C(N)N)OC3=CC=C(C=C3)N=C(N)N)N=C(N)N	Ki = 12022644.35 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	B2L0RO	1-[(1R,2R,4S,5S)-5-Carbamimidamido-2,4-bis(2,4-dicarbamimidamidophenoxy)cyclohexyl]guanidine	Investigative	11628682	C24H38N18O2	610.7	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC2=C(C=C(C=C2)N=C(N)N)N=C(N)N)OC3=C(C=C(C=C3)N=C(N)N)N=C(N)N)N=C(N)N	Ki = 169824365.3 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	B2U9XL	2-Benzylidenehydrazinecarboximidamide	Investigative	9568045	C8H10N4	162.19	C1=CC=C(C=C1)/C=N/N=C(N)N	Ki > 500000 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	B38ZLG	N-{4-[(1S,2S,4R,5R)-2,4-Diguanidino-5-(4-guanidino-phenoxy)-cyclohexyloxy]-3-guanidino-phenyl}-guanidine	Investigative	44593129	C23H35N15O2	553.6	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC2=C(C=C(C=C2)N=C(N)N)N=C(N)N)OC3=CC=C(C=C3)N=C(N)N)N=C(N)N	Ki = 89125093.81 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	B7RM4Q	(1S,2S,4R,5R)-2,4-Dicarbamimidamido-5-{[(3-carbamimidamidophenyl)carbamoyl]oxy}cyclohexyl N-(3-carbamimidamidophenyl)carbamate	Investigative	44593172	C24H34N14O4	582.6	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC(=O)NC2=CC(=CC=C2)N=C(N)N)OC(=O)NC3=CC(=CC=C3)N=C(N)N)N=C(N)N	Ki = 562341325.2 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	B87BSD	N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(4-guanidino-naphthalen-1-yloxy)-cyclohexyl]-guanidine	Investigative	44593147	C30H36N12O2	596.7	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC2=CC=C(C3=CC=CC=C32)N=C(N)N)OC4=CC=C(C5=CC=CC=C54)N=C(N)N)N=C(N)N	Ki = 69183097.09 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	B8QSA5	N-[(1S,2S,4R,5R)-5-Guanidino-2,4-bis-(5-guanidino-pyridin-2-yloxy)-cyclohexyl]-guanidine	Investigative	44593168	C20H30N14O2	498.5	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC2=NC=C(C=C2)N=C(N)N)OC3=NC=C(C=C3)N=C(N)N)N=C(N)N	Ki = 41686938.35 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	BG1OM3	(1S,2S,4R,5R)-2,4-Dicarbamimidamido-5-{[(4-carbamimidamidophenyl)carbamoyl]oxy}cyclohexyl N-(4-carbamimidamidophenyl)carbamate	Investigative	44593171	C24H34N14O4	582.6	C1[C@H]([C@@H](C[C@@H]([C@H]1N=C(N)N)OC(=O)NC2=CC=C(C=C2)N=C(N)N)OC(=O)NC3=CC=C(C=C3)N=C(N)N)N=C(N)N	Ki = 812830516.2 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	BJ9Y6C	1-[(1~{r},2~{r},4~{s},5~{s})-2,4-Bis(4-Carbamimidamidophenoxy)-5-[(4-Carbamimidamidophenyl)amino]cyclohexyl]guanidine	Investigative	44593169	C28H37N13O2	587.7	C1[C@@H]([C@H](C[C@H]([C@@H]1N=C(N)N)OC2=CC=C(C=C2)N=C(N)N)OC3=CC=C(C=C3)N=C(N)N)NC4=CC=C(C=C4)N=C(N)N	Ki = 45708818.96 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	BK5J2E	1-[(1R,2R,4S,5S)-5-[(4-Carbamimidamidonaphthalen-1-yl)amino]-2,4-bis[(4-carbamimidamidonaphthalen-1-yl)oxy]cyclohexyl]guanidine	Investigative	44593170	C40H43N13O2	737.9	C1[C@@H]([C@H](C[C@H]([C@@H]1N=C(N)N)OC2=CC=C(C3=CC=CC=C32)N=C(N)N)OC4=CC=C(C5=CC=CC=C54)N=C(N)N)NC6=CC=C(C7=CC=CC=C76)N=C(N)N	Ki = 426579518.8 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	BKH4S6	N-{4-[(1S,2S,4R,5R)-2,4-Diguanidino-5-(4-guanidino-naphthalen-1-yloxy)-cyclohexyloxy]-3-guanidino-phenyl}-guanidine	Investigative	44593130	C27H37N15O2	603.7	C1[C@@H]([C@H](C[C@H]([C@@H]1N=C(N)N)OC2=CC=C(C3=CC=CC=C32)N=C(N)N)OC4=C(C=C(C=C4)N=C(N)N)N=C(N)N)N=C(N)N	Ki = 407380277.8 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	BTS0X6	N-[(1S,2S,4R,5R)-2-(2-Amino-4-guanidino-phenoxy)-5-guanidino-4-(4-guanidino-naphthalen-1-yloxy)-cyclohexyl]-guanidine	Investigative	44593146	C26H35N13O2	561.6	C1[C@@H]([C@H](C[C@H]([C@@H]1N=C(N)N)OC2=CC=C(C3=CC=CC=C32)N=C(N)N)OC4=C(C=C(C=C4)N=C(N)N)N)N=C(N)N	Ki = 21877616.24 nM	Non binder
T98945	HUMAN dibasic-processing enzyme	BZBE59	N-[(1S,2S,4R,5R)-5-Guanidino-4-(4-guanidino-naphthalen-1-yloxy)-2-(4-guanidino-phenoxy)-cyclohexyl]-guanidine	Investigative	16043267	C26H34N12O2	546.6	C1[C@@H]([C@H](C[C@H]([C@@H]1N=C(N)N)OC2=CC=C(C3=CC=CC=C32)N=C(N)N)OC4=CC=C(C=C4)N=C(N)N)N=C(N)N	Ki = 6025595.86 nM	Non binder