TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T00140	Arachidonate 5-lipoxygenase	D0YG7M	Ketotifen	Approved	3827	C19H19NOS	309.4	CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B03TFO	5-(Methylamino)-2-naphthalen-1-yl-1,3-thiazole-4-carbonitrile	Investigative	70701468	C15H11N3S	265.3	CNC1=C(N=C(S1)C2=CC=CC3=CC=CC=C32)C#N	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B0JD4M	4-((1-Hydroxy-6-oxo-1,6-dihydropyridin-3-yl)ethynyl)benzenesulfonamide	Investigative	44561036	C13H10N2O4S	290.3	C1=CC(=CC=C1C#CC2=CN(C(=O)C=C2)O)S(=O)(=O)N	IC50 = 68000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B0VE5G	(5E)-5-(5-Chloro-2-hydroxy-3-methoxybenzylidene)-3-(4-fluorobenzyl)-1,3-thiazolidine-2,4-dione	Investigative	1229519	C18H13ClFNO4S	393.8	COC1=CC(=CC(=C1O)/C=C/2\\C(=O)N(C(=O)S2)CC3=CC=C(C=C3)F)Cl	IC50 = 68000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B0XW3R	Methyl 4-[({[(2-phenyl-4-quinolinyl)carbonyl]amino}carbothioyl)amino]benzoate	Investigative	996799	C25H19N3O3S	441.5	COC(=O)C1=CC=C(C=C1)NC(=S)NC(=O)C2=CC(=NC3=CC=CC=C32)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B12IXO	Substituted chalcone, 5c	Investigative	42618003	C21H22O4	338.4	CC(=CCOC1=CC(=C(C=C1)C(=O)/C=C/C2=CC=C(C=C2)OC)O)C	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B16ZGO	N-(2-Methylphenyl)-6-nitro-1,2-benzothiazol-3-amine 1,1-dioxide	Investigative	4690153	C14H11N3O4S	317.32	CC1=CC=CC=C1NC2=NS(=O)(=O)C3=C2C=CC(=C3)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B19DSV	2''-Hydroxy-2,3,4-trimethoxy-4''-O-prenylchalcone	Investigative	49864057	C23H26O6	398.4	CC(=CCOC1=CC(=C(C=C1)C(=O)/C=C/C2=C(C(=C(C=C2)OC)OC)OC)O)C	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B1DHQ6	1-(2,3-Dimethoxyphenyl)-4-[(4-methylsulfanylphenyl)methoxy]but-2-yn-1-ol	Investigative	56968387	C20H22O4S	358.5	COC1=CC=CC(=C1OC)C(C#CCOCC2=CC=C(C=C2)SC)O	IC50 = 69000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B1FUX5	Methyl (5-methyl-4-phenyl-1,3-thiazol-2-yl)carbamate	Investigative	1220478	C12H12N2O2S	248.3	CC1=C(N=C(S1)NC(=O)OC)C2=CC=CC=C2	IC50 = 89000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B1NL7A	1-Acetyl-2-phenylhydrazine	Investigative	8247	C8H10N2O	150.18	CC(=O)NNC1=CC=CC=C1	IC50 = 65000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B1XKC6	[2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]-(4-fluorophenyl)methanone;hydrochloride	Investigative	46845030	C34H37ClF2N2O5	627.1	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=CC=C(C=C6)F.Cl	IC50 = 58000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B2A4QF	1-(4-Methoxy-phenyl)-tetrahydro-pyridazin-3-one	Investigative	15056511	C11H14N2O2	206.24	COC1=CC=C(C=C1)N2CCCC(=O)N2	IC50 = 156000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B2ASL0	Potassium;2-[[4-(3,7-dimethyloctoxy)phenyl]methoxy]-6-hydroxybenzoate	Investigative	72735224	C24H31KO5	438.6	CC(C)CCCC(C)CCOC1=CC=C(C=C1)COC2=CC=CC(=C2C(=O)[O-])O.[K+]	Ki = 70300 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B2CE1Y	12-Oxo-ETE	Investigative	5283162	C20H30O3	318.4	CCCCC/C=C\\CC(=O)/C=C/C=C\\C/C=C\\CCCC(=O)O	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B2CSU1	1-(4-Ethyl-phenyl)-tetrahydro-pyridazin-3-one	Investigative	15056517	C12H16N2O	204.27	CCC1=CC=C(C=C1)N2CCCC(=O)N2	IC50 = 125000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B2HVY1	2-Chloro-5-[5-({2-[(4-fluorophenyl)amino]-2-oxoethyl}sulfanyl)-1H-tetrazol-1-yl]benzoic acid	Investigative	1017552	C16H11ClFN5O3S	407.8	C1=CC(=CC=C1NC(=O)CSC2=NN=NN2C3=CC(=C(C=C3)Cl)C(=O)O)F	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B2P7TD	4-(2-Tetradecyl-cyclopropyl)-butyric acid	Investigative	44378000	C21H40O2	324.5	CCCCCCCCCCCCCCC1CC1CCCC(=O)O	IC50 = 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B2U3QL	N-[(3-Bromophenyl)methyl]-6-nitro-1,1-dioxo-1,2-benzothiazol-3-imine	Investigative	136056624	C14H10BrN3O4S	396.22	C1=CC(=CC(=C1)Br)CN=C2C3=C(C=C(C=C3)[N+](=O)[O-])S(=O)(=O)N2	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B3H6BK	Chembl4287548	Investigative	145993378	C25H29N3O3	419.5	COC1=CC2=C(C=C1)NC(=CC2=O)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B3RBW1	3-(Benzyloxycarbonyl)benzoic acid	Investigative	13918608	C15H12O4	256.25	C1=CC=C(C=C1)COC(=O)C2=CC=CC(=C2)C(=O)O	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B3U7FN	Chembl4291372	Investigative	145987838	C26H30N2O4	434.5	COC1=CC2=C(C=C1)OC(=CC2=O)C(=O)NCCCC3CCN(CC3)CC4=CC=CC=C4	IC50 = 82400 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B3WM1B	3-Benzyl-6-(3,4-dichlorophenyl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole	Investigative	1816908	C16H10Cl2N4S	361.2	C1=CC=C(C=C1)CC2=NN=C3N2N=C(S3)C4=CC(=C(C=C4)Cl)Cl	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B4AV8Z	Chembl4287970	Investigative	145992723	C26H30N2O5	450.5	COC1=C(C=C2C(=C1)C(=O)C=C(O2)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4)OC	IC50 = 74300 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B4IBH5	1-(4-Chloro-phenyl)-tetrahydro-pyridazin-3-one	Investigative	15056542	C10H11ClN2O	210.66	C1CC(=O)NN(C1)C2=CC=C(C=C2)Cl	IC50 = 79000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B4LS7Z	(1E,6E)-1,7-Bis[4-hydroxy-3-methoxy-5-(3-methylbutyl)phenyl]hepta-1,6-diene-3,5-dione	Investigative	90644815	C31H40O6	508.6	CC(CCC1=C(C(=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C(=C2)OC)O)CCC(C)C)OC)O)C	IC50 = 80200 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B4SK0Y	[2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]-phenylmethanone;hydrochloride	Investigative	46906729	C34H38ClFN2O5	609.1	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=CC=CC=C6.Cl	IC50 = 66400 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B4SOV6	3-(Phenylcarbamoyl)benzoic acid	Investigative	20376778	C14H11NO3	241.24	C1=CC=C(C=C1)NC(=O)C2=CC(=CC=C2)C(=O)O	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B4VN7T	2-[(E)-{2-[(4-Chloro-1-methyl-1H-pyrazol-5-yl)carbonyl]hydrazinylidene}methyl]phenyl 4-nitrobenzoate	Investigative	6874154	C19H14ClN5O5	427.8	CN1C(=C(C=N1)Cl)C(=O)N/N=C/C2=CC=CC=C2OC(=O)C3=CC=C(C=C3)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B50RUF	3-(3-Bromophenyl)-N-[1-(4-fluorobenzyl)-3,5-dimethyl-1H-pyrazol-4-yl]-4,5-dihydro-5-isoxazolecarboxamide	Investigative	2962247	C22H20BrFN4O2	471.3	CC1=C(C(=NN1CC2=CC=C(C=C2)F)C)NC(=O)C3CC(=NO3)C4=CC(=CC=C4)Br	IC50 = 65000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B52OKG	15-Oxo-ETE	Investigative	5280701	C20H30O3	318.4	CCCCCC(=O)/C=C/C=C\\C/C=C\\C/C=C\\CCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B57ZJG	Chembl4282135	Investigative	145981314	C17H13FO4	300.28	CCOC(=O)C1=C(OC2=C1C=C(C=C2)O)C3=CC=CC=C3F	IC50 = 97500 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B5HS1Y	N-(1,3-Benzothiazol-2-yl)-4-[(2-hydroxy-3-methoxyphenyl)methylamino]benzenesulfonamide	Investigative	70701426	C21H19N3O4S2	441.5	COC1=CC=CC(=C1O)CNC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4S3	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B5JTA1	2-(3,4-Dichlorophenyl)-5-(methylamino)-1,3-oxazole-4-carbonitrile	Investigative	70701465	C11H7Cl2N3O	268.1	CNC1=C(N=C(O1)C2=CC(=C(C=C2)Cl)Cl)C#N	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B5TH8A	N-(3,4-Dimethoxyphenyl)-3,5-dinitrobenzamide	Investigative	7034541	C15H13N3O7	347.28	COC1=C(C=C(C=C1)NC(=O)C2=CC(=CC(=C2)[N+](=O)[O-])[N+](=O)[O-])OC	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B5Y8KH	8-Hydroxy-2-methyl-1-{2-[4-(4-methylpyridin-2-yl) piperazin-1-yl]ethyl}-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline	Investigative	10475519	C24H30N4O	390.5	CC1=CC(=NC=C1)N2CCN(CC2)CCC3=C(N4CCCC5=C4C3=CC(=C5)O)C	IC50 = 84000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B64UBQ	3,5-Dinitro-benzoic acid biphenyl-4-yl ester	Investigative	607148	C19H12N2O6	364.3	C1=CC=C(C=C1)C2=CC=C(C=C2)OC(=O)C3=CC(=CC(=C3)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B69OWD	Chembl4294783	Investigative	145993498	C27H32N2O5	464.6	COC1=C(C=C2C(=C1)C(=O)C=C(O2)C(=O)NCCCC3CCN(CC3)CC4=CC=CC=C4)OC	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B6WJU2	4-[(4-Methylsulfanylphenyl)methoxy]-1-(2,3,4-trimethoxyphenyl)but-2-yn-1-ol	Investigative	56968388	C21H24O5S	388.5	COC1=C(C(=C(C=C1)C(C#CCOCC2=CC=C(C=C2)SC)O)OC)OC	IC50 = 72000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B71HJN	2,3-Dichlorophenyl 3,5-dinitrobenzoate	Investigative	7038010	C13H6Cl2N2O6	357.1	C1=CC(=C(C(=C1)Cl)Cl)OC(=O)C2=CC(=CC(=C2)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B71VJI	N-(2-Benzoxazolyl)-4-(2-hydroxy-3-methoxybenzylamino)benzenesulfonamide	Investigative	70701432	C21H19N3O5S	425.5	COC1=CC=CC(=C1O)CNC2=CC=C(C=C2)S(=O)(=O)NC3=NC4=CC=CC=C4O3	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B74YBF	Chembl4285779	Investigative	145990611	C25H28N2O4	420.5	COC1=CC2=C(C=C1)C(=O)C=C(O2)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B7E0FK	Chembl4295144	Investigative	145993580	C25H28N2O5	436.5	COC1=C(C=C2C(=C1)C(=O)C=C(O2)C(=O)NCC3CCN(CC3)CC4=CC=CC=C4)OC	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B7J5BO	Chembl4291296	Investigative	145988042	C24H26N2O4	406.5	C1CN(CCC1CCNC(=O)C2=CC(=O)C3=C(O2)C=CC(=C3)O)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B80KFG	3-Fluorobenzoic acid 4-[[5-(1-naphthalenyl)-1,3,4-oxadiazol-2-yl]thio]but-2-ynyl ester	Investigative	44460128	C23H15FN2O3S	418.4	C1=CC=C2C(=C1)C=CC=C2C3=NN=C(O3)SCC#CCOC(=O)C4=CC(=CC=C4)F	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B86HQC	1-(3,4-Dimethoxyphenyl)-4-[(4-methylsulfanylphenyl)methoxy]but-2-yn-1-ol	Investigative	56968389	C20H22O4S	358.5	COC1=C(C=C(C=C1)C(C#CCOCC2=CC=C(C=C2)SC)O)OC	IC50 = 80000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B86ZAV	2-(1,3-Benzothiazol-2-yl)-4-[1-[(3,4-dichlorophenyl)methylamino]ethylidene]-5-(trifluoromethyl)pyrazol-3-one	Investigative	4984206	C20H13Cl2F3N4OS	485.3	CC(=NCC1=CC(=C(C=C1)Cl)Cl)C2=C(NN(C2=O)C3=NC4=CC=CC=C4S3)C(F)(F)F	IC50 = 70000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B8AE6Y	2-Methyl-8-quinolyl 3-nitrobenzoate	Investigative	814008	C17H12N2O4	308.29	CC1=NC2=C(C=CC=C2OC(=O)C3=CC(=CC=C3)[N+](=O)[O-])C=C1	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B8RKI5	3-(4-Methoxyphenyl)-6-[(E)-2-(2-methoxyphenyl)ethenyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole	Investigative	6229062	C19H16N4O2S	364.4	COC1=CC=C(C=C1)C2=NN=C3N2N=C(S3)/C=C/C4=CC=CC=C4OC	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B8UFA5	5-(Methylamino)-2-(1-naphthalenyl)-4-oxazolecarbonitrile	Investigative	664510	C15H11N3O	249.27	CNC1=C(N=C(O1)C2=CC=CC3=CC=CC=C32)C#N	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B8XZ9P	1-Phenyl-4-phenylmethoxybut-2-yn-1-ol	Investigative	56968384	C17H16O2	252.31	C1=CC=C(C=C1)COCC#CC(C2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B92BGM	Meso-3,3'-Didemethoxynectandrin B	Investigative	14213224	C18H20O3	284.3	C[C@@H]1[C@@H]([C@H](O[C@H]1C2=CC=C(C=C2)O)C3=CC=C(C=C3)O)C	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B98CKD	Rataniaphenol III	Investigative	14213215	C18H16O3	280.3	C/C=C/C1=CC2=C(C=C1)OC(=C2)C3=C(C=C(C=C3)O)OC	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B9ADJ5	1-(2-Chloro-phenyl)-tetrahydro-pyridazin-3-one	Investigative	15056540	C10H11ClN2O	210.66	C1CC(=O)NN(C1)C2=CC=CC=C2Cl	IC50 = 99000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B9G0DM	2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-5-[(4-methylsulfonylphenyl)methyl]-3,4-dihydro-1H-pyrido[4,3-b]indole;hydrochloride	Investigative	46845034	C35H42ClFN2O6S	673.2	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)CC6=CC=C(C=C6)S(=O)(=O)C.Cl	IC50 = 76600 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B9O0GV	N-(3-Chlorophenyl)-3,5-dinitrobenzamide	Investigative	4078425	C13H8ClN3O5	321.67	C1=CC(=CC(=C1)Cl)NC(=O)C2=CC(=CC(=C2)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B9OVR5	4-[(2S,3R)-3-(Hydroxymethyl)-5-[(E)-prop-1-enyl]-2,3-dihydro-1-benzofuran-2-yl]phenol	Investigative	71460125	C18H18O3	282.3	C/C=C/C1=CC2=C(C=C1)O[C@@H]([C@H]2CO)C3=CC=C(C=C3)O	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B9PBS0	[2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]-(2,4,6-trichlorophenyl)methanone;hydrochloride	Investigative	46906737	C34H35Cl4FN2O5	712.5	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=C(C=C(C=C6Cl)Cl)Cl.Cl	IC50 = 55000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B9Q4SI	15-Oxo-puupehenoic Acid	Investigative	44557858	C22H28O4	356.5	C[C@]12CCCC([C@@H]1CC[C@]3([C@@H]2C(=O)C4=C(C=CC=C4O3)C(=O)O)C)(C)C	IC50 ~ 150000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B9QF0D	1-{[6-(2,3-Dihydro-1,4-benzodioxin-2-yl)[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl]methyl}-1H-1,2,3-benzotriazole	Investigative	2971957	C18H13N7O2S	391.4	C1C(OC2=CC=CC=C2O1)C3=NN4C(=NN=C4S3)CN5C6=CC=CC=C6N=N5	IC50 = 97000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	B9RPV5	2-(4-Hydroxyphenyl)-5-(E)-propenylbenzofuran	Investigative	53483951	C17H14O2	250.29	C/C=C/C1=CC2=C(C=C1)OC(=C2)C3=CC=C(C=C3)O	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BA34CR	Tert-butyl N-[(3-nitrophenyl)sulfonylamino]carbamate	Investigative	3136217	C11H15N3O6S	317.32	CC(C)(C)OC(=O)NNS(=O)(=O)C1=CC=CC(=C1)[N+](=O)[O-]	IC50 = 81000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BA5HJ4	N'-[4-[2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indole-5-carbonyl]phenyl]sulfonyl-N,N-dimethylmethanimidamide;hydrochloride	Investigative	46906741	C37H44ClFN4O7S	743.3	CN(C)/C=N/S(=O)(=O)C1=CC=C(C=C1)C(=O)N2C3=C(CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C6=C2C=CC(=C6)OC.Cl	IC50 = 81400 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BB1G0W	1-(4-Methoxyphenyl)-4-[(4-methylsulfanylphenyl)methoxy]but-2-yn-1-ol	Investigative	56968386	C19H20O3S	328.4	COC1=CC=C(C=C1)C(C#CCOCC2=CC=C(C=C2)SC)O	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BB5KC8	N-(3-Chlorophenyl)-6-nitro-1,2-benzothiazol-3-amine 1,1-dioxide	Investigative	2883254	C13H8ClN3O4S	337.74	C1=CC(=CC(=C1)Cl)NC2=NS(=O)(=O)C3=C2C=CC(=C3)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BBK1J3	N-[(8-Hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]propanamide	Investigative	3136123	C17H16N2O2S	312.4	CCC(=O)NC(C1=C(C2=C(C=CC=N2)C=C1)O)C3=CC=CS3	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BBM81L	Chembl4290401	Investigative	145987800	C25H29N3O3	419.5	COC1=CC=CC2=C1NC(=CC2=O)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BC2XE7	N-[(5-Chloro-8-hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]propanamide	Investigative	3136134	C17H15ClN2O2S	346.8	CCC(=O)NC(C1=CC=CS1)C2=CC(=C3C=CC=NC3=C2O)Cl	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BC56YD	1-[(4-Methylsulfanylphenyl)methoxy]non-2-yn-4-ol	Investigative	56968385	C17H24O2S	292.4	CCCCCC(C#CCOCC1=CC=C(C=C1)SC)O	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BC5KF4	7-Tert-butyl-3,3-dimethyl-N-propyl-2H-1-benzofuran-5-carboxamide	Investigative	9947925	C18H27NO2	289.4	CCCNC(=O)C1=CC2=C(C(=C1)C(C)(C)C)OCC2(C)C	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BCHG64	Chembl4293801	Investigative	145988798	C26H31N3O4	449.5	COC1=C(C=C2C(=C1)C(=O)C=C(N2)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4)OC	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BCV23L	5-Hydroxymethyl-icosa-6,8,11,14-tetraenoic acid	Investigative	44271973	C21H34O3	334.5	CCCCC/C=C\\C/C=C\\C/C=C\\C=C\\C(CCCC(=O)O)CO	IC50 = 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BCW57P	N-[(5-Bromo-8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]acetamide	Investigative	44460175	C16H13BrN2O2S	377.3	CC(=O)NC(C1=CC=CS1)C2=CC(=C3C=CC=NC3=C2O)Br	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BD8PA2	4-Methoxy-2'',4''-di-O-prenylchalcone	Investigative	49864060	C26H30O4	406.5	CC(=CCOC1=CC(=C(C=C1)C(=O)/C=C/C2=CC=C(C=C2)OC)OCC=C(C)C)C	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BD8PK7	4-Methyl-2-[5-(2-methylphenyl)-1H-pyrazol-3-yl]phenol	Investigative	775994	C17H16N2O	264.32	CC1=CC(=C(C=C1)O)C2=NNC(=C2)C3=CC=CC=C3C	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BE0H6Z	6-Nitro-1,1-dioxo-N-quinolin-5-yl-1,2-benzothiazol-3-amine	Investigative	90643933	C16H10N4O4S	354.3	C1=CC2=C(C=CC=N2)C(=C1)NC3=NS(=O)(=O)C4=C3C=CC(=C4)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BE3T7X	2''-Hydroxy-2,3-dimethoxy-4''-O-prenylchalcone	Investigative	49864056	C22H24O5	368.4	CC(=CCOC1=CC(=C(C=C1)C(=O)/C=C/C2=C(C(=CC=C2)OC)OC)O)C	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BE6WX1	N-(3-Bromophenyl)-3,5-dinitrobenzamide	Investigative	4228320	C13H8BrN3O5	366.12	C1=CC(=CC(=C1)Br)NC(=O)C2=CC(=CC(=C2)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BE7ZK5	13-Keto-9Z,11E-octadecadienoic acid	Investigative	6446027	C18H30O3	294.4	CCCCCC(=O)/C=C/C=C\\CCCCCCCC(=O)O	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BECV95	N-[2-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-oxoethyl]-4-ethoxy-N-phenylbenzenesulfonamide	Investigative	987980	C25H26N2O4S	450.6	CCOC1=CC=C(C=C1)S(=O)(=O)N(CC(=O)N2CCC3=CC=CC=C3C2)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BEP5R6	N-[(5-Chloro-8-hydroxyquinolin-7-yl)-(furan-2-yl)methyl]propanamide	Investigative	2920571	C17H15ClN2O3	330.8	CCC(=O)NC(C1=CC=CO1)C2=CC(=C3C=CC=NC3=C2O)Cl	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BFAS35	N-Cyclopropyl-3,3-dimethyl-7-tert-butyl-2,3-dihydro-5-benzofurancarboxamide	Investigative	10517413	C18H25NO2	287.4	CC1(COC2=C1C=C(C=C2C(C)(C)C)C(=O)NC3CC3)C	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BFLN45	2-(2,4-Dihydroxyphenyl)-5-(e)-propenylbenzofuran	Investigative	10355545	C17H14O3	266.29	C/C=C/C1=CC2=C(C=C1)OC(=C2)C3=C(C=C(C=C3)O)O	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BG65MT	2,5-Dihydroxybenzoic acid	Investigative	3469	C7H6O4	154.12	C1=CC(=C(C=C1O)C(=O)O)O	IC50 = 75000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BGA2M3	N-(3-Methylphenyl)-3,5-dinitrobenzamide	Investigative	5036963	C14H11N3O5	301.25	CC1=CC(=CC=C1)NC(=O)C2=CC(=CC(=C2)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BGT25V	6-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[(phenylsulfanyl)methyl][1,2,4]triazolo[3,4-b][1,3,4]thiadiazole	Investigative	9507010	C18H14N4O2S2	382.5	C1COC2=C(O1)C=CC(=C2)C3=NN4C(=NN=C4S3)CSC5=CC=CC=C5	IC50 = 70000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BGY5Q6	4-(3-Tetradeca-1,3,5,8-tetraenyl-thiiranyl)-butyric acid methyl ester	Investigative	44378349	C21H32O2S	348.5	CCCCC/C=C\\C/C=C\\C=C\\C=C\\C1C(S1)CCCC(=O)OC	IC50 = 65000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BHO5R1	4-Chloro-3-nitro-N-(9H-xanthen-9-yl)benzamide	Investigative	1237983	C20H13ClN2O4	380.8	C1=CC=C2C(=C1)C(C3=CC=CC=C3O2)NC(=O)C4=CC(=C(C=C4)Cl)[N+](=O)[O-]	IC50 = 67000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BI8X9Y	4-(5-(Naphthalen-1-yl)-1,3,4-oxadiazol-2-ylthio)but-2-ynyl benzo[b]thiophene-2-carboxylate	Investigative	44460130	C25H16N2O3S2	456.5	C1=CC=C2C(=C1)C=CC=C2C3=NN=C(O3)SCC#CCOC(=O)C4=CC5=CC=CC=C5S4	IC50 ~ 75000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BIC60G	1-[5-Chloro-6-(4-chlorophenyl)-2-benzoxazolyl]-N-[(1S,3S)-3-(hydroxymethyl)cyclohexyl]-4-piperidinecarboxamide	Investigative	53252516	C26H29Cl2N3O3	502.4	C1C[C@@H](C[C@H](C1)NC(=O)C2CCN(CC2)C3=NC4=C(O3)C=C(C(=C4)Cl)C5=CC=C(C=C5)Cl)CO	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BION27	Chembl4281021	Investigative	145982182	C17H12Cl2O4	351.2	CCOC(=O)C1=C(OC2=C1C=C(C=C2)O)C3=CC(=C(C=C3)Cl)Cl	IC50 = 54300 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BJON65	[2-[3-[3-Fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]-phenylmethanone;hydrochloride	Investigative	46906731	C33H36ClFN2O4	579.1	COC1(CCOCC1)C2=CC(=CC(=C2)F)OCCCN3CCC4=C(C3)C5=CC=CC=C5N4C(=O)C6=CC=CC=C6.Cl	IC50 = 92900 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BK3B6Y	4-{[5-(4-Chlorophenyl)-1,3,4-oxadiazol-2-yl]sulfanyl}but-2-yn-1-yl 4-fluorobenzoate	Investigative	44460139	C19H12ClFN2O3S	402.8	C1=CC(=CC=C1C2=NN=C(O2)SCC#CCOC(=O)C3=CC=C(C=C3)F)Cl	IC50 ~ 75000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BK73IX	(4Z)-2-(4-Chloro-3-nitrophenyl)-4-(2,3,4-trimethoxybenzylidene)-1,3-oxazol-5(4H)-one	Investigative	1219517	C19H15ClN2O7	418.8	COC1=C(C(=C(C=C1)/C=C\\2/C(=O)OC(=N2)C3=CC(=C(C=C3)Cl)[N+](=O)[O-])OC)OC	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BKE3N6	1-o-Tolyl-tetrahydro-pyridazin-3-one	Investigative	15056538	C11H14N2O	190.24	CC1=CC=CC=C1N2CCCC(=O)N2	IC50 = 57000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BL0VX8	Chembl4283450	Investigative	145993208	C25H28N2O4	420.5	COC1=CC2=C(C=C1)OC(=CC2=O)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BL27ZA	N-[2-({5-Nitro-2-furoyl}amino)ethyl]-2-quinolinecarboxamide	Investigative	17600320	C17H14N4O5	354.32	C1=CC=C2C(=C1)C=CC(=N2)C(=O)NCCNC(=O)C3=CC=C(O3)[N+](=O)[O-]	IC50 = 82000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BLQ1P3	Chembl4286799	Investigative	145993120	C24H26N2O3	390.5	C1CN(CCC1CCNC(=O)C2=CC(=O)C3=CC=CC=C3O2)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BLU42T	4-[(4-Methylsulfanylphenyl)methoxy]-1-(3,4,5-trimethoxyphenyl)but-2-yn-1-ol	Investigative	56968390	C21H24O5S	388.5	COC1=CC(=CC(=C1OC)OC)C(C#CCOCC2=CC=C(C=C2)SC)O	IC50 = 80000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BM01BX	2-(2,3-Dichlorophenyl)-5-(methylamino)-1,3-oxazole-4-carbonitrile	Investigative	70701462	C11H7Cl2N3O	268.1	CNC1=C(N=C(O1)C2=C(C(=CC=C2)Cl)Cl)C#N	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BML96G	(2Z)-2-(4-Hydroxy-3-iodo-5-nitrobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one	Investigative	1823617	C16H8IN3O4S	465.2	C1=CC=C2C(=C1)N=C3N2C(=O)/C(=C/C4=CC(=C(C(=C4)I)O)[N+](=O)[O-])/S3	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BMO68U	2-{3-Nitro-5-[(4-methylphenyl)sulfanyl]-1H-1,2,4-triazol-1-yl}-1-phenylethanone	Investigative	1309076	C17H14N4O3S	354.4	CC1=CC=C(C=C1)SC2=NC(=NN2CC(=O)C3=CC=CC=C3)[N+](=O)[O-]	IC50 = 76000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BNJ26I	7-(4-Bromophenyl)-9,9-dioxo-7lambda4,9lambda6-dithia-8-azabicyclo[4.3.0]nona-1(6),2,4,7-tetraene-3-sulfonamide	Investigative	57397393	C12H9BrN2O4S3	421.3	C1=CC(=CC=C1S2=NS(=O)(=O)C3=C2C=CC(=C3)S(=O)(=O)N)Br	IC50 = 91100 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BNSQ20	1-[2,2'']Bipyridinyl-6-yl-[1,2,4]triazinan-3-one	Investigative	10824904	C13H13N5O	255.28	C1CN(NC(=O)N1)C2=CC=CC(=N2)C3=CC=CC=N3	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BNW6Q7	N-[(5-Chloro-8-hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]acetamide	Investigative	2920793	C16H13ClN2O2S	332.8	CC(=O)NC(C1=CC=CS1)C2=CC(=C3C=CC=NC3=C2O)Cl	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BO5JK9	2''-Hydroxy-3,4,5-trimethoxy-4''-O-prenylchalcone	Investigative	49864059	C23H26O6	398.4	CC(=CCOC1=CC(=C(C=C1)C(=O)/C=C/C2=CC(=C(C(=C2)OC)OC)OC)O)C	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BP34KB	(4-Bromophenyl)-[2-[3-[3-fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]methanone;hydrochloride	Investigative	46906739	C34H37BrClFN2O5	688	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=CC=C(C=C6)Br.Cl	IC50 = 62000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BP7T4Y	3-Naphthalen-1-yloxycarbonylbenzoic acid	Investigative	71359348	C18H12O4	292.3	C1=CC=C2C(=C1)C=CC=C2OC(=O)C3=CC=CC(=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BP95FO	N-(4-Chloro-2-methylphenyl)-2-(4-oxo-5,6,7,8-tetrahydro[1]benzothieno[2,3-d][1,2,3]triazin-3(4H)-yl)acetamide	Investigative	993074	C18H17ClN4O2S	388.9	CC1=C(C=CC(=C1)Cl)NC(=O)CN2C(=O)C3=C(N=N2)SC4=C3CCCC4	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BPY75C	4-{[5-(3-Chlorophenyl)-2-furyl]methylene}-2-(3-methylphenyl)-1,3-oxazol-5(4H)-one	Investigative	1733195	C21H14ClNO3	363.8	CC1=CC(=CC=C1)C2=N/C(=C\\C3=CC=C(O3)C4=CC(=CC=C4)Cl)/C(=O)O2	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BR9U0J	N'-Phenylbutanehydrazide	Investigative	2750392	C10H14N2O	178.23	CCCC(=O)NNC1=CC=CC=C1	IC50 = 52000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BS48IY	(-)-Larreatricin	Investigative	26389403	C18H20O3	284.3	C[C@@H]1[C@@H]([C@H](O[C@@H]1C2=CC=C(C=C2)O)C3=CC=C(C=C3)O)C	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BS6H4P	2'-Hydroxy-3,4-dimethoxy-4'-(3-methyl-2-butenyloxy)chalcone	Investigative	49864058	C22H24O5	368.4	CC(=CCOC1=CC(=C(C=C1)C(=O)/C=C/C2=CC(=C(C=C2)OC)OC)O)C	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BSH5V7	Eupomatenoid 6	Investigative	6261723	C18H16O2	264.3	C/C=C/C1=CC2=C(C=C1)OC(=C2C)C3=CC=C(C=C3)O	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BSQ01Y	3,5-Dinitro-N-(3-phenylphenyl)benzamide	Investigative	90654808	C19H13N3O5	363.3	C1=CC=C(C=C1)C2=CC(=CC=C2)NC(=O)C3=CC(=CC(=C3)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BT5J8V	(4-Chlorophenyl)-[2-[3-[3-fluoro-5-(4-methoxyoxan-4-yl)phenoxy]propyl]-8-methoxy-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl]methanone;hydrochloride	Investigative	46845032	C34H37Cl2FN2O5	643.6	COC1=CC2=C(C=C1)N(C3=C2CN(CC3)CCCOC4=CC(=CC(=C4)C5(CCOCC5)OC)F)C(=O)C6=CC=C(C=C6)Cl.Cl	IC50 = 59300 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BU0R1Q	4-(4-Chlorobenzylidene)-2-(2-naphthyl)-1,3-oxazol-5(4H)-one	Investigative	1732961	C20H12ClNO2	333.8	C1=CC=C2C=C(C=CC2=C1)C3=N/C(=C\\C4=CC=C(C=C4)Cl)/C(=O)O3	IC50 = 80000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BUCV42	4-[(4-Methylsulfanylphenyl)methoxy]-1-(3-nitrophenyl)but-2-yn-1-ol	Investigative	56968615	C18H17NO4S	343.4	CSC1=CC=C(C=C1)COCC#CC(C2=CC(=CC=C2)[N+](=O)[O-])O	IC50 = 62000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BUT2R4	N-(5-Bromonaphthalen-1-yl)-6-nitro-1,1-dioxo-1,2-benzothiazol-3-amine	Investigative	90643934	C17H10BrN3O4S	432.2	C1=CC2=C(C=CC=C2Br)C(=C1)NC3=NS(=O)(=O)C4=C3C=CC(=C4)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BV0OX5	Chembl4277332	Investigative	145984359	C24H26N2O5	422.5	C1CN(CCC1CCNC(=O)C2=CC(=O)C3=C(C=C(C=C3O2)O)O)CC4=CC=CC=C4	IC50 = 95100 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BW0Q1S	Chembl4292720	Investigative	145986960	C17H13ClO4	316.7	CCOC(=O)C1=C(OC2=C1C=C(C=C2)O)C3=CC=CC=C3Cl	IC50 = 59500 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BW80TZ	N-[(3-Bromophenyl)methyl]-3,5-dinitrobenzamide	Investigative	90654809	C14H10BrN3O5	380.15	C1=CC(=CC(=C1)Br)CNC(=O)C2=CC(=CC(=C2)[N+](=O)[O-])[N+](=O)[O-]	IC50 = 83600 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BW8Y5H	N1-Naphthyl-3,5-dinitrobenzamide	Investigative	3116544	C17H11N3O5	337.29	C1=CC=C2C(=C1)C=CC=C2NC(=O)C3=CC(=CC(=C3)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BWT56D	Chembl4282527	Investigative	145979972	C25H29N3O3	419.5	COC1=CC2=C(C=C1)C(=O)C=C(N2)C(=O)NCCC3CCN(CC3)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BX3G9B	2-(Furan-2-yl)-1H-1,3-benzodiazol-5-amine	Investigative	744225	C11H9N3O	199.21	C1=COC(=C1)C2=NC3=C(N2)C=C(C=C3)N	IC50 = 66000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BX42KY	1-(3-Hydroxymethyl-phenyl)-tetrahydro-pyridazin-3-one	Investigative	5061930	C11H14N2O2	206.24	C1CC(=O)NN(C1)C2=CC=CC(=C2)CO	IC50 = 53000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BX6K2C	Rataniaphenol I	Investigative	6440631	C18H16O3	280.3	C/C=C/C1=CC2=C(C=C1)OC(=C2)C3=C(C=C(C=C3)OC)O	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BXN39U	3-(Naphthalen-1-ylcarbamoyl)benzoic acid	Investigative	15496169	C18H13NO3	291.3	C1=CC=C2C(=C1)C=CC=C2NC(=O)C3=CC(=CC=C3)C(=O)O	IC50 ~ 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BXU05A	N-(2-Methoxyethyl)-7-tert-butyl-2,3-dihydro-3,3-dimethylbenzofuran-5-carboxamide	Investigative	10335263	C18H27NO3	305.4	CC1(COC2=C1C=C(C=C2C(C)(C)C)C(=O)NCCOC)C	IC50 = 50000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BZ04AL	Morusin	Investigative	5281671	C25H24O6	420.5	CC(=CCC1=C(OC2=C(C1=O)C(=CC3=C2C=CC(O3)(C)C)O)C4=C(C=C(C=C4)O)O)C	IC50 = 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BZ2H6G	Chembl4285912	Investigative	145992212	C24H27N3O3	405.5	C1CN(CCC1CCNC(=O)C2=CC(=O)C3=C(N2)C(=CC=C3)O)CC4=CC=CC=C4	IC50 = 77600 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	BZG91P	Chembl4283079	Investigative	145981823	C22H22N2O4	378.4	C1CN(CCC1NC(=O)C2=CC(=O)C3=C(O2)C=CC(=C3)O)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	D05QOR	SCOPOLETIN	Investigative	5280460	C10H8O4	192.17	COC1=C(C=C2C(=C1)C=CC(=O)O2)O	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	D0E0RW	ISOSCOPOLETIN	Investigative	69894	C10H8O4	192.17	COC1=C(C=C2C=CC(=O)OC2=C1)O	IC50 ~ 100000 nM	Poor binder
T00140	Arachidonate 5-lipoxygenase	D0I9AT	tryptanthrin	Investigative	73549	C15H8N2O2	248.24	C1=CC=C2C(=C1)C(=O)N3C4=CC=CC=C4C(=O)C3=N2	IC50 = 200000 nM	Poor binder