TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T02551	Dopamine D3 receptor	D0T7OW	Dopamine	Approved	681	C8H11NO2	153.18	C1=CC(=C(C=C1CCN)O)O	Ki ~ 80000 nM	Poor binder
T02551	Dopamine D3 receptor	B0FKC5	N-Pentan-2-yl-1H-indole-2-carboxamide	Investigative	43398192	C14H18N2O	230.31	CCCC(C)NC(=O)C1=CC2=CC=CC=C2N1	Ki ~ 50000 nM	Poor binder
T02551	Dopamine D3 receptor	B1HYO7	(11R)-5-Methyl-6,11-dioxo-N-(2-thiophen-2-ylethyl)benzo[b][1,4]benzothiazepine-3-carboxamide	Investigative	57383408	C21H18N2O3S2	410.5	CN1C2=C(C=CC(=C2)C(=O)NCCC3=CC=CS3)[S@](=O)C4=CC=CC=C4C1=O	Ki ~ 50000 nM	Poor binder
T02551	Dopamine D3 receptor	B43PEY	[4-(4-Chloro-phenyl)-piperazin-1-yl]-pyrazolo[1,5-a]pyridin-3-yl-methanone	Investigative	44264741	C18H17ClN4O	340.8	C1CN(CCN1C2=CC=C(C=C2)Cl)C(=O)C3=C4C=CC=CN4N=C3	Ki = 61000 nM	Poor binder
T02551	Dopamine D3 receptor	B4G1WA	3-[4-(4-Chlorophenyl)piperazinomethyl]-4-(hydroxymethyl)pyrazolo[1,5-a]pyridine	Investigative	44372312	C19H21ClN4O	356.8	C1CN(CCN1CC2=C3C(=CC=CN3N=C2)CO)C4=CC=C(C=C4)Cl	Ki ~ 100000 nM	Poor binder
T02551	Dopamine D3 receptor	B8VTK7	1-(4-Fluorophenyl)-6-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-1,6-diazaspiro[3.3]heptane	Investigative	137662048	C23H26FN5S	423.6	CN1C(=NN=C1SCCCN2CC3(C2)CCN3C4=CC=C(C=C4)F)C5=CC=CC=C5	Ki = 181888 nM	Poor binder
T02551	Dopamine D3 receptor	B9PM5U	N-(Propan-2-yl)-1H-indole-2-carboxamide	Investigative	13680883	C12H14N2O	202.25	CC(C)NC(=O)C1=CC2=CC=CC=C2N1	Ki ~ 100000 nM	Poor binder
T02551	Dopamine D3 receptor	B9TSU0	N-Heptan-4-yl-1H-indole-2-carboxamide	Investigative	57527911	C16H22N2O	258.36	CCCC(CCC)NC(=O)C1=CC2=CC=CC=C2N1	Ki ~ 100000 nM	Poor binder
T02551	Dopamine D3 receptor	BC2SZ6	(2S)-4-(1H-Benzimidazol-2-ylmethyl)-2-(2-phenylethyl)morpholine	Investigative	92640710	C20H23N3O	321.4	C1CO[C@H](CN1CC2=NC3=CC=CC=C3N2)CCC4=CC=CC=C4	IC50 = 76400 nM	Poor binder
T02551	Dopamine D3 receptor	BP69UG	(4As,5R,10bR)-5-phenyl-1,2,3,4,4a,5,6,10b-octahydrobenzo[h]isoquinoline-7,8-diol	Investigative	46869265	C19H21NO2	295.4	C1CNC[C@@H]2[C@@H]1[C@@H](CC3=C2C=CC(=C3O)O)C4=CC=CC=C4	Ki = 130000 nM	Poor binder
T02551	Dopamine D3 receptor	BT7BW6	3-{[4-(2-Methoxyphenyl)piperazin-1-yl]methyl}-2,7-dimethylimidazo[1,2-c]pyrimidine	Investigative	45267409	C20H25N5O	351.4	CC1=CC2=NC(=C(N2C=N1)CN3CCN(CC3)C4=CC=CC=C4OC)C	Ki = 67000 nM	Poor binder
T02551	Dopamine D3 receptor	BY9IU1	2-[4-(4-Fluorophenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyrimidine	Investigative	11652518	C17H18FN5	311.36	C1CN(CCN1CC2=CN3C=CC=NC3=N2)C4=CC=C(C=C4)F	Ki = 60000 nM	Poor binder
T02551	Dopamine D3 receptor	BZ9UC6	N-(Cyclopropylmethyl)-1H-indole-2-carboxamide	Investigative	23025506	C13H14N2O	214.26	C1CC1CNC(=O)C2=CC3=CC=CC=C3N2	Ki ~ 100000 nM	Poor binder