TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T03634	CREB-binding protein	D09CKU	PMID26394986-Compound-44	Patented	65064	C22H18O11	458.4	C1[C@H]([C@H](OC2=CC(=CC(=C21)O)O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O	IC50 = 50000 nM	Poor binder
T03634	CREB-binding protein	B2HM8O	(2S)-2-(Hydroxymethyl)-1,2,3,5-tetrahydro-1,5-benzodiazepin-4-one	Investigative	69236418	C10H12N2O2	192.21	C1[C@H](NC2=CC=CC=C2NC1=O)CO	IC50 = 130000 nM	Poor binder
T03634	CREB-binding protein	B2ISO1	4-Cyano-N-(1,3-diethyl-2-oxoquinolin-6-yl)benzenesulfonamide	Investigative	137636309	C20H19N3O3S	381.4	CCC1=CC2=C(C=CC(=C2)NS(=O)(=O)C3=CC=C(C=C3)C#N)N(C1=O)CC	IC50 ~ 100000 nM	Poor binder
T03634	CREB-binding protein	B31GKY	(E)-4-(5-Acetyl-2-fluoroanilino)-4-oxobut-2-enoic acid	Investigative	127026318	C12H10FNO4	251.21	CC(=O)C1=CC(=C(C=C1)F)NC(=O)/C=C/C(=O)O	IC50 ~ 100000 nM	Poor binder
T03634	CREB-binding protein	B5V9FR	1-(4-Benzoyl-1-phenyl-1H-pyrazole-3-yl)ethanone	Investigative	45917950	C18H14N2O2	290.3	CC(=O)C1=NN(C=C1C(=O)C2=CC=CC=C2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T03634	CREB-binding protein	B5Y8IE	(E)-4-(5-Acetyl-2-methylanilino)-4-oxobut-2-enoic acid	Investigative	127025709	C13H13NO4	247.25	CC1=C(C=C(C=C1)C(=O)C)NC(=O)/C=C/C(=O)O	IC50 ~ 100000 nM	Poor binder
T03634	CREB-binding protein	B6NS1M	3-Methyl-6-amino-2(3H)-benzothiazolone	Investigative	10442296	C8H8N2OS	180.23	CN1C2=C(C=C(C=C2)N)SC1=O	IC50 ~ 100000 nM	Poor binder
T03634	CREB-binding protein	B8UGW2	4-Acetyl-3,5-dimethyl-N-[2-methyl-5-(1,3,4-oxadiazol-2-yl)phenyl]-1H-pyrrole-2-carboxamide	Investigative	51081283	C18H18N4O3	338.4	CC1=C(C=C(C=C1)C2=NN=CO2)NC(=O)C3=C(C(=C(N3)C)C(=O)C)C	IC50 ~ 100000 nM	Poor binder
T03634	CREB-binding protein	B9E4BN	Coumarin, 3-amino-4-(1-pyrrolidinyl)-	Investigative	43001	C13H14N2O2	230.26	C1CCN(C1)C2=C(C(=O)OC3=CC=CC=C32)N	IC50 ~ 50000 nM	Poor binder
T03634	CREB-binding protein	BA05VB	1-Acetylbenzimidazole-2-carbonitrile	Investigative	46786182	C10H7N3O	185.18	CC(=O)N1C2=CC=CC=C2N=C1C#N	IC50 ~ 50000 nM	Poor binder
T03634	CREB-binding protein	BA0QL7	Chembl4162464	Investigative	755980	C15H16N2O	240.3	CC(=O)C1=NN(C2=C1CCCC2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T03634	CREB-binding protein	BBW5S4	Methyl indole-3-carboxylate	Investigative	589098	C10H9NO2	175.18	COC(=O)C1=CNC2=CC=CC=C21	IC50 = 99000 nM	Poor binder
T03634	CREB-binding protein	BDL03Y	N-(9-Acetylcarbazol-3-yl)acetamide	Investigative	3326945	C16H14N2O2	266.29	CC(=O)NC1=CC2=C(C=C1)N(C3=CC=CC=C32)C(=O)C	IC50 ~ 50000 nM	Poor binder
T03634	CREB-binding protein	BF9DY0	(2E)-4-[(5-Acetyl-2-methoxyphenyl)amino]-4-oxobut-2-enoic acid	Investigative	6210261	C13H13NO5	263.25	CC(=O)C1=CC(=C(C=C1)OC)NC(=O)/C=C/C(=O)O	IC50 = 60000 nM	Poor binder
T03634	CREB-binding protein	BFZ60M	2-[(5-Acetyl-2-ethoxyphenyl)carbamoyl]cyclopropane-1-carboxylic acid	Investigative	127026319	C15H17NO5	291.3	CCOC1=C(C=C(C=C1)C(=O)C)NC(=O)C2CC2C(=O)O	IC50 ~ 100000 nM	Poor binder
T03634	CREB-binding protein	BKE95T	2-[(5-Acetyl-2-ethoxyphenyl)carbamoyl]benzoic acid	Investigative	118626421	C18H17NO5	327.3	CCOC1=C(C=C(C=C1)C(=O)C)NC(=O)C2=CC=CC=C2C(=O)O	IC50 = 64000 nM	Poor binder
T03634	CREB-binding protein	BL19OJ	(1-Acetylindol-3-yl)methyl acetate	Investigative	1238761	C13H13NO3	231.25	CC(=O)N1C=C(C2=CC=CC=C21)COC(=O)C	IC50 ~ 50000 nM	Poor binder
T03634	CREB-binding protein	BL73OJ	(2R)-2-Ethyl-1,2,3,5-tetrahydro-1,5-benzodiazepin-4-one	Investigative	121277645	C11H14N2O	190.24	CC[C@@H]1CC(=O)NC2=CC=CC=C2N1	IC50 = 120000 nM	Poor binder
T03634	CREB-binding protein	BMP6X7	Chembl4160970	Investigative	145959144	C22H23N3O4	393.4	CCCCNC1=C(C=C(C=C1)C(=O)O)NC(=O)C2=CN(C3=CC=CC=C32)C(=O)C	IC50 ~ 50000 nM	Poor binder
T03634	CREB-binding protein	BO75JV	6-{(5Z)-5-[1-(4-Fluorobenzyl)-2-oxo-1,2-dihydro-3H-indol-3-ylidene]-4-oxo-2-thioxo-1,3-thiazolidin-3-yl}hexanoic acid	Investigative	1600566	C24H21FN2O4S2	484.6	C1=CC=C2C(=C1)/C(=C/3\\C(=O)N(C(=S)S3)CCCCCC(=O)O)/C(=O)N2CC4=CC=C(C=C4)F	IC50 = 115700 nM	Poor binder
T03634	CREB-binding protein	BR2ZH8	1-[3-(3,5-Dimethyl-1,2-oxazol-4-yl)phenyl]ethanone	Investigative	44243549	C13H13NO2	215.25	CC1=C(C(=NO1)C)C2=CC(=CC=C2)C(=O)C	IC50 = 55700 nM	Poor binder
T03634	CREB-binding protein	BR9OE5	Chembl4291134	Investigative	56877138	C17H19N5O3	341.4	C1C(NC(=O)CN1)C(=O)NCCN2C(=O)C=CC(=N2)C3=CC=CC=C3	IC50 = 55000 nM	Poor binder
T03634	CREB-binding protein	BST4M7	Chembl4160237	Investigative	145956646	C15H10N2O3	266.25	C1=CC=C2C(=C1)C(C=NC2=O)C3=CC(=CC=C3)[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T03634	CREB-binding protein	BTC3A5	4-(3-Ethoxyphenyl)-3,5-dimethyl-1,2-oxazole	Investigative	54757749	C13H15NO2	217.26	CCOC1=CC=CC(=C1)C2=C(ON=C2C)C	IC50 = 86900 nM	Poor binder
T03634	CREB-binding protein	BU7L5E	4-(4-Chlorophenyl)-2-methylphthalazin-1-one	Investigative	5157255	C15H11ClN2O	270.71	CN1C(=O)C2=CC=CC=C2C(=N1)C3=CC=C(C=C3)Cl	IC50 ~ 50000 nM	Poor binder
T03634	CREB-binding protein	BWJF73	Coumarin, 3-amino-4-anilino-	Investigative	43000	C15H12N2O2	252.27	C1=CC=C(C=C1)NC2=C(C(=O)OC3=CC=CC=C32)N	IC50 ~ 50000 nM	Poor binder
T03634	CREB-binding protein	BX04HG	3,4-Diacetyl-5-methyl-1-phenylpyrazole	Investigative	12689741	C14H14N2O2	242.27	CC1=C(C(=NN1C2=CC=CC=C2)C(=O)C)C(=O)C	IC50 ~ 50000 nM	Poor binder
T03634	CREB-binding protein	BX69FZ	5-(3,5-Dimethyl-1,2-Oxazol-4-Yl)-1-[2-(Morpholin-4-Yl)ethyl]-2-(2-Phenylethyl)-1h-Benzimidazole	Investigative	72201025	C26H30N4O2	430.5	CC1=C(C(=NO1)C)C2=CC3=C(C=C2)N(C(=N3)CCC4=CC=CC=C4)CCN5CCOCC5	IC50 = 160000 nM	Poor binder
T03634	CREB-binding protein	BYG59O	N-[3-(3,4-Dihydro-2H-quinolin-1-yl)propyl]-2-methyl-3-oxo-4H-1,4-benzoxazine-8-carboxamide	Investigative	122664496	C22H25N3O3	379.5	CC1C(=O)NC2=CC=CC(=C2O1)C(=O)NCCCN3CCCC4=CC=CC=C43	IC50 = 51000 nM	Poor binder