TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T04820	Plasmodium CDK Pfmrk	D09EGZ	Chloroquine	Approved	2719	C18H26ClN3	319.9	CCN(CC)CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl	IC50 = 150000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	D0L4FS	Genistein	Phase 2	5280961	C15H10O5	270.24	C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O	IC50 = 93000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	B0YSL4	1-(4-Methoxyphenyl)-3-(1-naphthyl)prop-2-en-1-one	Investigative	5708687	C20H16O2	288.3	COC1=CC=C(C=C1)C(=O)/C=C/C2=CC=CC3=CC=CC=C32	IC50 ~ 100000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	B62JNG	7-Hydroxy-10H-11-oxa-10-aza-benzo[b]fluoren-5-one	Investigative	11989520	C15H9NO3	251.24	C1=CC=C2C(=C1)C3=C(O2)NC4=C(C3=O)C=C(C=C4)O	IC50 = 187000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	B6C7XF	3-(Naphthalen-1-yl)-1-(2,3,4-trimethoxyphenyl)prop-2-en-1-one	Investigative	44419434	C22H20O4	348.4	COC1=C(C(=C(C=C1)C(=O)/C=C/C2=CC=CC3=CC=CC=C32)OC)OC	IC50 = 50000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	B7RUG8	4-(3-(4-Chlorophenyl)acryloyl)benzonitrile	Investigative	24426485	C16H10ClNO	267.71	C1=CC(=CC=C1/C=C/C(=O)C2=CC=C(C=C2)C#N)Cl	IC50 ~ 100000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	B7VEC4	1H-Indole-2(3H)-one, 3-(4-trifluoromethylbenzylidene)-	Investigative	5378325	C16H10F3NO	289.25	C1=CC=C2C(=C1)/C(=C\\C3=CC=C(C=C3)C(F)(F)F)/C(=O)N2	IC50 = 138000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	B81WKZ	N-(4-Chloro-2-methyl-phenyl)-3-nitro-benzamide	Investigative	779201	C14H11ClN2O3	290.7	CC1=C(C=CC(=C1)Cl)NC(=O)C2=CC(=CC=C2)[N+](=O)[O-]	IC50 = 69000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	B8UA1D	N,N''-(2,4,6-Trimethyl-1,3-phenylene)bis(4-bromobenzenesulfonamide)	Investigative	49798456	C21H20Br2N2O4S2	588.3	CC1=CC(=C(C(=C1NS(=O)(=O)C2=CC=C(C=C2)Br)C)NS(=O)(=O)C3=CC=C(C=C3)Br)C	IC50 = 50200 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	B8WE4K	5-Bromo-3-(2-oxo-2-p-tolyl-ethylidene)-1,3-dihydro-indol-2-one	Investigative	44350563	C17H12BrNO2	342.2	CC1=CC=C(C=C1)C(=O)/C=C/2\\C3=C(C=CC(=C3)Br)NC2=O	IC50 = 120000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BB10NW	Ethyl 2-chloro-5-nitrobenzoate	Investigative	2774222	C9H8ClNO4	229.62	CCOC(=O)C1=C(C=CC(=C1)[N+](=O)[O-])Cl	IC50 = 87000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BCT59S	Ethyl 2-(3-nitrobenzoyl)-3-(pyridin-2-yl)acrylate	Investigative	44592001	C17H14N2O5	326.3	CCOC(=O)/C(=C\\C1=CC=CC=N1)/C(=O)C2=CC(=CC=C2)[N+](=O)[O-]	IC50 = 61000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BDP68L	(3Z)-3-[2-(4-Bromophenyl)-2-oxoethylidene]-1,3-dihydro-2H-indol-2-one	Investigative	947949	C16H10BrNO2	328.16	C1=CC=C2C(=C1)/C(=C/C(=O)C3=CC=C(C=C3)Br)/C(=O)N2	IC50 = 130000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BF7MQ0	5-Bromo-3-(2-oxo-2-phenylethylidene)-1,3-dihydroindol-2-one	Investigative	5477132	C16H10BrNO2	328.16	C1=CC=C(C=C1)C(=O)/C=C\\2/C3=C(C=CC(=C3)Br)NC2=O	IC50 = 120000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BIA7P3	2,2-Dichloro-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-p-tolylacetamide	Investigative	49798553	C13H9Cl4NO3S2	433.2	CC1=CC=C(C=C1)N(C(=O)C(Cl)Cl)S(=O)(=O)C2=C(SC(=C2)Cl)Cl	IC50 = 127200 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BKA52C	(Z)-2-(4-Nitro-benzoyl)-3-pyridin-2-yl-acrylic acid ethyl ester	Investigative	44396824	C17H14N2O5	326.3	CCOC(=O)/C(=C\\C1=CC=CC=N1)/C(=O)C2=CC=C(C=C2)[N+](=O)[O-]	IC50 = 61000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BL6IA2	3-[(Methylamino)methylidene]-1,3-dihydro-2H-indol-2-one	Investigative	135959419	C10H10N2O	174.2	CN=CC1=C(NC2=CC=CC=C21)O	IC50 ~ 57000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BO5X0M	(3-Oxo-1-phenyl-1,3-dihydro-isobenzofuran-1-yl)-thiourea	Investigative	44396873	C15H12N2O2S	284.3	C1=CC=C(C=C1)C2(C3=CC=CC=C3C(=O)O2)NC(=S)N	IC50 = 70000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BO8N9G	(3E)-5-Bromo-3-[2-(4-fluorophenyl)-2-oxoethylidene]-1H-indol-2-one	Investigative	6918711	C16H9BrFNO2	346.15	C1=CC(=CC=C1C(=O)/C=C/2\\C3=C(C=CC(=C3)Br)NC2=O)F	IC50 = 190000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BP46XY	3-[(E)-beta-Oxophenethylidene]indoline-2-one	Investigative	682361	C16H11NO2	249.26	C1=CC=C(C=C1)C(=O)/C=C/2\\C3=CC=CC=C3NC2=O	IC50 = 150000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BR1N4H	3-(2-Oxo-1,2-dihydroquinoline-3-yl)phenoxyacetic acid	Investigative	44329224	C17H13NO4	295.29	C1=CC=C2C(=C1)C=C(C(=O)N2)C3=CC(=CC=C3)OCC(=O)O	IC50 = 102000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BUV2H3	2-Hydrazino-3-(1H-indol-3-yl)-propionic acid	Investigative	13717983	C11H13N3O2	219.24	C1=CC=C2C(=C1)C(=CN2)CC(C(=O)O)NN	IC50 = 182000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	BW54CT	1-(2,4-Dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-en-1-one	Investigative	6476742	C21H18O3	318.4	COC1=CC(=C(C=C1)C(=O)/C=C/C2=CC3=CC=CC=C3C=C2)OC	IC50 = 100000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	D02NGU	H-8	Investigative	3540	C12H15N3O2S	265.33	CNCCNS(=O)(=O)C1=CC=CC2=C1C=CN=C2	IC50 = 70000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	D0H3EV	9-Nitropaullone	Investigative	5005498	C16H11N3O3	293.28	C1C2=C(C3=CC=CC=C3NC1=O)NC4=C2C=C(C=C4)[N+](=O)[O-]	IC50 = 51000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	D0KH5T	4-[3-Hydroxyanilino]-6,7-Dimethoxyquinazoline	Investigative	5687	C16H15N3O3	297.31	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC	IC50 = 168000 nM	Poor binder
T04820	Plasmodium CDK Pfmrk	D0T3PW	Myricetin	Investigative	5281672	C15H10O8	318.23	C1=C(C=C(C(=C1O)O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O	IC50 = 157000 nM	Poor binder