TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T06093	Rho-associated protein kinase 2	B0D8JY	N-(4-Aminomethyl-phenyl)-3-[3-(4-cyano-phenyl)-ureidomethyl]-benzamide	Investigative	25056367	C23H21N5O2	399.4	C1=CC(=CC(=C1)C(=O)NC2=CC=C(C=C2)CN)CNC(=O)NC3=CC=C(C=C3)C#N	IC50 = 70000 nM	Poor binder
T06093	Rho-associated protein kinase 2	B1A4GU	3-[3-(3-Chloro-4-amido-phenyl)-ureidomethyl]-N-(4-dimethylaminomethyl-phenyl)-benzamide	Investigative	44819373	C25H26ClN5O3	480	CN(C)CC1=CC=C(C=C1)NC(=O)C2=CC=CC(=C2)CNC(=O)NC3=CC(=C(C=C3)C(=O)N)Cl	IC50 = 74000 nM	Poor binder
T06093	Rho-associated protein kinase 2	B1V3UJ	Chembl4167272	Investigative	139589900	C17H27NO2	277.4	C/C(=C\\[C@H]1[C@@H]([C@@]([C@@H]2N1CCCC2)(C)O)O)/C=C/C3CC3	IC50 ~ 100000 nM	Poor binder
T06093	Rho-associated protein kinase 2	B3A4TN	Chembl4171044	Investigative	139589905	C17H29NO3	295.4	C/C(=C\\C=C\\CCO)/C[C@H]1[C@@H]([C@@]([C@@H]2N1CCCC2)(C)O)O	IC50 ~ 100000 nM	Poor binder
T06093	Rho-associated protein kinase 2	B3IP4L	Nicotinamide, N-(4-pyridyl)-	Investigative	3049109	C11H9N3O	199.21	C1=CC(=CN=C1)C(=O)NC2=CC=NC=C2	IC50 = 55900 nM	Poor binder
T06093	Rho-associated protein kinase 2	B46USG	3-(4-Methyl-1,4-diazepan-1-yl)-5-(3-methylpyridin-4-yl)pyrazin-2-amine	Investigative	11530100	C16H22N6	298.39	CC1=C(C=CN=C1)C2=CN=C(C(=N2)N3CCCN(CC3)C)N	IC50 = 58000 nM	Poor binder
T06093	Rho-associated protein kinase 2	B4Y5PJ	3,4-Dimethoxy-N-[3-(1,2,3,4-tetrahydro-isoquinolin-6-ylcarbamoyl)-benzyl]-benzamide	Investigative	25057668	C26H27N3O4	445.5	COC1=C(C=C(C=C1)C(=O)NCC2=CC(=CC=C2)C(=O)NC3=CC4=C(CNCC4)C=C3)OC	IC50 = 100000 nM	Poor binder
T06093	Rho-associated protein kinase 2	B98RFU	1-(1H-Indazol-5-yl)-3-phenylurea	Investigative	4421488	C14H12N4O	252.27	C1=CC=C(C=C1)NC(=O)NC2=CC3=C(C=C2)NN=C3	IC50 = 61800 nM	Poor binder
T06093	Rho-associated protein kinase 2	BB25XZ	N-{3-[3-(4-Cyano-phenyl)-ureidomethyl]-phenyl}-3-piperidin-3-yl-propionamide	Investigative	25057407	C23H27N5O2	405.5	C1CC(CNC1)CCC(=O)NC2=CC=CC(=C2)CNC(=O)NC3=CC=C(C=C3)C#N	IC50 = 110000 nM	Poor binder
T06093	Rho-associated protein kinase 2	BC80AI	3,4-Dimethoxy-N-{3-[2-(1-methyl-piperidin-3-yl)-ethylcarbamoyl]-benzyl}-benzamide	Investigative	25057932	C25H33N3O4	439.5	CN1CCCC(C1)CCNC(=O)C2=CC=CC(=C2)CNC(=O)C3=CC(=C(C=C3)OC)OC	IC50 = 102000 nM	Poor binder
T06093	Rho-associated protein kinase 2	BG3X2S	N-[3-(4-Dimethylaminomethyl-phenylcarbamoyl)-benzyl]-4-methoxy-3-trifluoromethyl-benzamide	Investigative	25054309	C26H26F3N3O3	485.5	CN(C)CC1=CC=C(C=C1)NC(=O)C2=CC=CC(=C2)CNC(=O)C3=CC(=C(C=C3)OC)C(F)(F)F	IC50 = 160000 nM	Poor binder
T06093	Rho-associated protein kinase 2	BH9CP0	5-Aminoindazole	Investigative	88012	C7H7N3	133.15	C1=CC2=C(C=C1N)C=NN2	IC50 = 119700 nM	Poor binder
T06093	Rho-associated protein kinase 2	BK2GQ1	N-Benzyl-N-methyl-4-(phenylsulfamoyl)benzamide	Investigative	27666048	C21H20N2O3S	380.5	CN(CC1=CC=CC=C1)C(=O)C2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T06093	Rho-associated protein kinase 2	BLI17W	3-(4-Methyl-1,4-diazepan-1-yl)-5-(2-methylpyridin-4-yl)pyrazin-2-amine	Investigative	46229922	C16H22N6	298.39	CC1=NC=CC(=C1)C2=CN=C(C(=N2)N3CCCN(CC3)C)N	IC50 ~ 100000 nM	Poor binder
T06093	Rho-associated protein kinase 2	BLV7G9	Chembl4174482	Investigative	139589903	C17H22NO2+	272.36	C/C(=C\\[C@H]1[C@@H]([C@@](C2=CC=CC=[N+]12)(C)O)O)/C=C/C3CC3	IC50 ~ 100000 nM	Poor binder
T06093	Rho-associated protein kinase 2	BP05ZW	Cyclizidine	Investigative	9994431	C17H25NO3	291.4	C/C(=C\\[C@H]1[C@@H]([C@@]([C@@H]2N1CC[C@@H]3[C@H]2O3)(C)O)O)/C=C/C4CC4	IC50 ~ 100000 nM	Poor binder
T06093	Rho-associated protein kinase 2	BR80DW	5-(2-Aminopyridin-4-yl)-3-(4-methyl-1,4-diazepan-1-yl)pyrazin-2-amine	Investigative	11536733	C15H21N7	299.37	CN1CCCN(CC1)C2=NC(=CN=C2N)C3=CC(=NC=C3)N	IC50 = 53000 nM	Poor binder
T06093	Rho-associated protein kinase 2	BT0D9L	N-(2-Methoxyethyl)-3-(4-methyl-1,4-diazepan-1-yl)-5-(pyridin-4-yl)pyrazin-2-amine	Investigative	46230027	C18H26N6O	342.4	CN1CCCN(CC1)C2=NC(=CN=C2NCCOC)C3=CC=NC=C3	IC50 = 52000 nM	Poor binder
T06093	Rho-associated protein kinase 2	BT21AL	3-[3-(4-Cyano-phenyl)-ureidomethyl]-N-(2-piperidin-4-yl-ethyl)-benzamide	Investigative	25056366	C23H27N5O2	405.5	C1CNCCC1CCNC(=O)C2=CC=CC(=C2)CNC(=O)NC3=CC=C(C=C3)C#N	IC50 = 65000 nM	Poor binder
T06093	Rho-associated protein kinase 2	BU51XY	1-[(1R)-2,3-Dihydro-1H-inden-1-yl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea	Investigative	87407564	C18H16N4OS	336.4	C1CC2=CC=CC=C2[C@@H]1NC(=O)NC3=NC(=CS3)C4=CC=NC=C4	IC50 = 52470 nM	Poor binder
T06093	Rho-associated protein kinase 2	BX49HM	Chembl4163816	Investigative	139589902	C17H26ClNO3	327.8	C/C(=C\\[C@H]1[C@@H]([C@@]([C@@H]2N1CC[C@@H]([C@H]2O)Cl)(C)O)O)/C=C/C3CC3	IC50 ~ 100000 nM	Poor binder