TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T06273	Poly [ADP-ribose] polymerase 1	B0FCK2	CID 66716841	Investigative	66716841	C23H27ClN4O3	442.9	CCNC(=O)C1=CC(=C(C=C1)N2CCN(CC2)CC3=CC4=C(C=C3)OC(C(=O)N4)C)Cl	EC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B0MK9O	4-(4-Carbamoylphenoxy)benzamide	Investigative	236501	C14H12N2O3	256.26	C1=CC(=CC=C1C(=O)N)OC2=CC=C(C=C2)C(=O)N	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B0NCM2	Chembl4290954	Investigative	121398248	C21H24N4O4S2	460.6	CC1=NC=C(S1)CN2C(=O)C3=C(C=CC(=C3)S(=O)(=O)NC4(CC4)C)N(C2=O)CC5CC5	EC50 ~ 150000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B0P4AJ	5-(Adamantan-1-ylcarboxamido)isoquinolin-1-one	Investigative	52936896	C20H22N2O2	322.4	C1C2CC3CC1CC(C2)(C3)C(=O)NC4=CC=CC5=C4C=CNC5=O	IC50 ~ 50000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B0R7CZ	IWR-1-endo	Investigative	44483163	C25H19N3O3	409.4	C1[C@@H]2C=C[C@H]1[C@@H]3[C@H]2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6	IC50 ~ 85000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B13PAT	CID 66716805	Investigative	66716805	C25H32N4O3	436.5	CCNC(=O)C1=CC(=C(C=C1)N2CCN(CC2)CC3=CC4=C(C(=C3)C)OC(C(=O)N4)C)C	EC50 = 55000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B1KTA9	2-Fluoro-N-(1-oxo-3,4-dihydro-2H-isoquinolin-4-yl)-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzamide	Investigative	71605031	C25H19FN4O3	442.4	C1C(C2=CC=CC=C2C(=O)N1)NC(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F	IC50 = 86340 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B2RYT0	CID 66716949	Investigative	66716949	C26H32N4O4	464.6	CC1C(=O)NC2=C(O1)C(=CC(=C2)CN3CCN(CC3)C4=C(C=C(C=C4)C(=O)NC5CC5)C)OC	EC50 = 77000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B3W7HN	2-Amino-5-[4-[(4S)-5,5-dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]cyclohexyl]pyridine-3-carbonitrile	Investigative	72724967	C23H26N4O2	390.5	CC1([C@@H](N(C(=O)O1)C2CCC(CC2)C3=CC(=C(N=C3)N)C#N)C4=CC=CC=C4)C	IC50 ~ 85000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B4NR6Q	CID 66717219	Investigative	66717219	C24H30N4O4	438.5	CC1C(=O)NC2=C(O1)C(=CC(=C2)CN3CCN(CC3)C4=C(C=C(C=C4)C(=O)NC)C)OC	EC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B4OK5I	3,5-Dichloro-N-(3-chloro-4-naphthalen-2-yloxyphenyl)-2-hydroxybenzamide	Investigative	53387188	C23H14Cl3NO3	458.7	C1=CC=C2C=C(C=CC2=C1)OC3=C(C=C(C=C3)NC(=O)C4=C(C(=CC(=C4)Cl)Cl)O)Cl	IC50 = 120000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B4X3EA	N-[(4-Oxo-3,5,7,8-tetrahydropyrano[4,3-d]pyrimidin-2-yl)methyl]-3-phenyl-N-(thiophen-3-ylmethyl)propanamide	Investigative	136232699	C22H23N3O3S	409.5	C1COCC2=C1N=C(NC2=O)CN(CC3=CSC=C3)C(=O)CCC4=CC=CC=C4	IC50 = 71000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B50LQP	(Z)-5-((1H-Indol-3-yl)methylene)thiazolidine-2,4-dione	Investigative	135420896	C12H8N2O2S	244.27	C1=CC=C2C(=C1)/C(=C/C3=C(NC(=O)S3)O)/C=N2	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B58HDN	Chembl4293745	Investigative	121398630	C23H27N7O4S	497.6	CC1=NN(C(=C1)CN2C3=C(C=C(C=C3)S(=O)(=O)NC4(CC4)C)C(=O)N(C2=O)CC5=CN(N=C5)C)C	EC50 ~ 150000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B67FGZ	12,14-Dimethyl-9,11,17-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2,4,6,12,14,16-heptaen-8-one	Investigative	46225777	C16H13N3O	263.29	CC1=CC2=NC3=C(N2C(=C1)C)NC(=O)C4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B69OWY	4-Fluorobenzamide	Investigative	71572	C7H6FNO	139.13	C1=CC(=CC=C1C(=O)N)F	IC50 = 200000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B6CG2H	2-(4-Bromophenyl)-8-methoxy-1H-quinazolin-4-one	Investigative	136491263	C15H11BrN2O2	331.16	COC1=CC=CC2=C1N=C(NC2=O)C3=CC=C(C=C3)Br	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B6O4GP	7-Methoxy-3,4-dihydroisoquinolin-1(2H)-one	Investigative	13521672	C10H11NO2	177.2	COC1=CC2=C(CCNC2=O)C=C1	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B6PHU1	3,4-Dihydroisoquinolin-1(2H)-one	Investigative	150896	C9H9NO	147.17	C1CNC(=O)C2=CC=CC=C21	IC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B7GZ8Q	2-[(3-Chloro-4-naphthalen-2-yloxyphenyl)carbamoyl]benzoic acid	Investigative	56658117	C24H16ClNO4	417.8	C1=CC=C2C=C(C=CC2=C1)OC3=C(C=C(C=C3)NC(=O)C4=CC=CC=C4C(=O)O)Cl	IC50 = 66000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B7PZ1E	7-(Trifluoromethyl)-3,4-dihydroisoquinolin-1(2H)-one	Investigative	66801593	C10H8F3NO	215.17	C1CNC(=O)C2=C1C=CC(=C2)C(F)(F)F	IC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B7R1BG	Pratol	Investigative	5320693	C16H12O4	268.26	COC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C=C3)O	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B82BCA	CID 66716892	Investigative	66716892	C24H30N4O3	422.5	CC1C(=O)NC2=C(O1)C(=CC(=C2)CN3CCN(CC3)C4=C(C=C(C=C4)C(=O)NC)C)C	EC50 = 78000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B82KFB	4-(4-Formyl-phenoxy)-benzamide	Investigative	28825277	C14H11NO3	241.24	C1=CC(=CC=C1C=O)OC2=CC=C(C=C2)C(=O)N	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B84PNF	N-[4-[(4S)-5,5-Dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]cyclohexyl]-7-fluoro-1,5-naphthyridine-4-carboxamide	Investigative	71681176	C26H27FN4O3	462.5	CC1([C@@H](N(C(=O)O1)C2CCC(CC2)NC(=O)C3=C4C(=NC=C3)C=C(C=N4)F)C5=CC=CC=C5)C	IC50 ~ 85000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B87AZR	5-(Cyclohexanecarboxamido)isoquinolin-1-one	Investigative	52936894	C16H18N2O2	270.33	C1CCC(CC1)C(=O)NC2=CC=CC3=C2C=CNC3=O	IC50 ~ 80000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B89NGX	2-Fluoro-N-(3-oxo-1,2-dihydroinden-1-yl)-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzamide	Investigative	71604870	C25H18FN3O3	427.4	C1C(C2=CC=CC=C2C1=O)NC(=O)C3=C(C=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54)F	IC50 = 83900 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B8FI2J	N-Cyclopropyl-4-[4-[(8-methoxy-2-methyl-3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperazin-1-yl]benzamide	Investigative	66716626	C25H30N4O4	450.5	CC1C(=O)NC2=C(O1)C(=CC(=C2)CN3CCN(CC3)C4=CC=C(C=C4)C(=O)NC5CC5)OC	EC50 = 162000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B8P5HN	N-[4-(3-Bromonaphthalen-2-yl)oxy-3-chlorophenyl]-3,5-dichloro-2-hydroxybenzamide	Investigative	56665040	C23H13BrCl3NO3	537.6	C1=CC=C2C=C(C(=CC2=C1)OC3=C(C=C(C=C3)NC(=O)C4=C(C(=CC(=C4)Cl)Cl)O)Cl)Br	IC50 = 123000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B94EWU	2-(4-Hydroxyphenyl)-1H-1,3-benzodiazole-7-carboxylic acid	Investigative	135456680	C14H10N2O3	254.24	C1=CC(=C2C(=C1)NC(=N2)C3=CC=C(C=C3)O)C(=O)O	Ki = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B96SDF	4-Methoxybenzamide	Investigative	76959	C8H9NO2	151.16	COC1=CC=C(C=C1)C(=O)N	IC50 = 57000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B98GZX	Chembl4125748	Investigative	145962722	C25H23FN2O4	434.5	C1CN(CCC1(C2=CC=C(C=C2)F)O)C(=O)C3=CC(=CC=C3)OC4=CC=C(C=C4)C(=O)N	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	B9MVQ8	N-Cyclopropyl-4-[4-[(8-ethoxy-2-methyl-3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperazin-1-yl]-3-methylbenzamide	Investigative	66716876	C27H34N4O4	478.6	CCOC1=CC(=CC2=C1OC(C(=O)N2)C)CN3CCN(CC3)C4=C(C=C(C=C4)C(=O)NC5CC5)C	EC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BB45HT	4-[4-[(8-Ethoxy-2-methyl-3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperazin-1-yl]-N-ethyl-3-methylbenzamide	Investigative	66716854	C26H34N4O4	466.6	CCNC(=O)C1=CC(=C(C=C1)N2CCN(CC2)CC3=CC4=C(C(=C3)OCC)OC(C(=O)N4)C)C	EC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BBL1A6	7-Bromo-3,4-dihydroisoquinolin-1(2H)-one	Investigative	25067330	C9H8BrNO	226.07	C1CNC(=O)C2=C1C=CC(=C2)Br	IC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BC1I3X	8-Methoxy-2-[4-(Trifluoromethyl)phenyl]-3,4-Dihydroquinazolin-4-One	Investigative	135513721	C16H11F3N2O2	320.27	COC1=CC=CC2=C1N=C(NC2=O)C3=CC=C(C=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BC5J4K	CID 66717080	Investigative	66717080	C24H30N4O4	438.5	CCNC(=O)C1=CC=C(C=C1)N2CCN(CC2)CC3=CC4=C(C(=C3)OC)OC(C(=O)N4)C	EC50 = 151000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BCO27X	N-(5,6-Dihydrothiazolo[2,3-c][1,2,4]triazol-3-yl)-3-methylbutanamide	Investigative	16031314	C9H14N4OS	226.3	CC(C)CC(=O)NC1=NN=C2N1CCS2	IC50 = 55300 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BD1EV4	1,2-Dihydro-2-(4-isopropylphenyl)-4(3H)-quinazolinone	Investigative	4163640	C17H18N2O	266.34	CC(C)C1=CC=C(C=C1)C2NC3=CC=CC=C3C(=O)N2	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BDX61C	4-[[4-Fluoro-3-(2-hydroxy-5-azatricyclo[6.3.1.04,12]dodeca-1(11),8(12),9-triene-5-carbonyl)phenyl]methyl]-2H-phthalazin-1-one	Investigative	71604867	C27H22FN3O3	455.5	C1CN(C2CC(C3=CC=CC1=C23)O)C(=O)C4=C(C=CC(=C4)CC5=NNC(=O)C6=CC=CC=C65)F	IC50 = 86200 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BE7B3U	6-Oxo-5,6-dihydrophenanthridine-10-carboxylic acid	Investigative	12494569	C14H9NO3	239.23	C1=CC=C2C(=C1)C3=C(C=CC=C3C(=O)O)C(=O)N2	IC50 ~ 60000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BEM90P	N-[3-Chloranyl-4-[[4-(4-Methoxyphenyl)oxan-4-Yl]methylcarbamoyl]phenyl]furan-2-Carboxamide	Investigative	89649815	C25H25ClN2O5	468.9	COC1=CC=C(C=C1)C2(CCOCC2)CNC(=O)C3=C(C=C(C=C3)NC(=O)C4=CC=CO4)Cl	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BEW1B3	4-[(2-Fluorophenyl)methoxy]benzamide	Investigative	8607850	C14H12FNO2	245.25	C1=CC=C(C(=C1)COC2=CC=C(C=C2)C(=O)N)F	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BG0J9S	CID 66717208	Investigative	66717208	C26H32N4O3	448.6	CC1C(=O)NC2=C(O1)C(=CC(=C2)CN3CCN(CC3)C4=C(C=C(C=C4)C(=O)NC5CC5)C)C	EC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BG25KO	(4s)-3-{trans-4-[6-Amino-5-(Pyrimidin-2-Yl)pyridin-3-Yl]cyclohexyl}-5,5-Dimethyl-4-Phenyl-1,3-Oxazolidin-2-One	Investigative	71660496	C26H29N5O2	443.5	CC1([C@@H](N(C(=O)O1)C2CCC(CC2)C3=CC(=C(N=C3)N)C4=NC=CC=N4)C5=CC=CC=C5)C	IC50 ~ 85000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BG75NL	2-(4-Tert-Butylphenyl)-2,3-dihydroquinazoline-4(1H)-one	Investigative	4826644	C18H20N2O	280.4	CC(C)(C)C1=CC=C(C=C1)C2NC3=CC=CC=C3C(=O)N2	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BH1TC7	2-(4-Fluorophenyl)quinazolin-4-ol	Investigative	135479130	C14H9FN2O	240.23	C1=CC=C2C(=C1)C(=O)NC(=N2)C3=CC=C(C=C3)F	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BI1O9C	4-[[3-(2,11-Diazatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene-2-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one	Investigative	71604716	C27H23FN4O2	454.5	C1CN(C2CNCC3=CC=CC1=C23)C(=O)C4=C(C=CC(=C4)CC5=NNC(=O)C6=CC=CC=C65)F	IC50 = 156000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BI3ES5	5-(2,2-Dimethylpropanamido)isoquinolin-1-one	Investigative	52936895	C14H16N2O2	244.29	CC(C)(C)C(=O)NC1=CC=CC2=C1C=CNC2=O	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BIJ93N	Chembl4290899	Investigative	121398509	C17H21N3O4S	363.4	CC1(CC1)NS(=O)(=O)C2=CC3=C(C=C2)N(C(=O)N(C3=O)C)CC4CC4	EC50 ~ 150000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BJ6XC4	Chembl4171592	Investigative	141746550	C14H12N4O	252.27	C1=CC=C(C(=C1)C2=NC3=C(C=CC=C3N2)C(=O)N)N	IC50 ~ 50000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BJ93XK	4-[4-[(2,8-Dimethyl-3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperazin-1-yl]-N-ethylbenzamide	Investigative	66717138	C24H30N4O3	422.5	CCNC(=O)C1=CC=C(C=C1)N2CCN(CC2)CC3=CC4=C(C(=C3)C)OC(C(=O)N4)C	EC50 = 94000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BJE4Q1	N-Cyclopropyl-4-[4-[(2,8-dimethyl-3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperazin-1-yl]benzamide	Investigative	46926923	C25H30N4O3	434.5	CC1C(=O)NC2=C(O1)C(=CC(=C2)CN3CCN(CC3)C4=CC=C(C=C4)C(=O)NC5CC5)C	EC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BJER35	2-(4-Bromophenyl)-3,4-Dihydroquinazolin-4-One	Investigative	135421564	C14H9BrN2O	301.14	C1=CC=C2C(=C1)C(=O)NC(=N2)C3=CC=C(C=C3)Br	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BJY9R1	1-[4-[(4S)-5,5-Dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]cyclohexyl]-6-fluoro-2-oxo-3H-benzimidazole-5-carbonitrile	Investigative	71681329	C25H25FN4O3	448.5	CC1([C@@H](N(C(=O)O1)C2CCC(CC2)N3C4=C(C=C(C(=C4)F)C#N)NC3=O)C5=CC=CC=C5)C	IC50 ~ 85000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BJZ93N	2-[4-(Trifluoromethyl)phenyl]-3h-Quinazolin-4-One	Investigative	135566970	C15H9F3N2O	290.24	C1=CC=C2C(=C1)C(=O)NC(=N2)C3=CC=C(C=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BK4H7S	3-Nitrobenzamide	Investigative	12576	C7H6N2O3	166.13	C1=CC(=CC(=C1)[N+](=O)[O-])C(=O)N	IC50 = 160000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BKJ2Y6	N-(1-Oxo-3,4-dihydro-2H-isoquinolin-4-yl)-3-[(4-oxo-3H-phthalazin-1-yl)methyl]benzamide	Investigative	71605032	C25H20N4O3	424.5	C1C(C2=CC=CC=C2C(=O)N1)NC(=O)C3=CC=CC(=C3)CC4=NNC(=O)C5=CC=CC=C54	IC50 = 145750 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BLUR60	7-Methyl-3,4-dihydroisoquinolin-1(2H)-one	Investigative	15507355	C10H11NO	161.2	CC1=CC2=C(CCNC2=O)C=C1	IC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BMP1C3	3-(3-(Trifluoromethyl)phenyl)quinoline-8-carboxamide	Investigative	25208597	C17H11F3N2O	316.28	C1=CC(=CC(=C1)C(F)(F)F)C2=CN=C3C(=C2)C=CC=C3C(=O)N	IC50 = 52000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BOV19K	7-Fluoro-3,4-dihydroisoquinolin-1(2H)-one	Investigative	17792611	C9H8FNO	165.16	C1CNC(=O)C2=C1C=CC(=C2)F	IC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BPH98F	12-Methyl-9,11,17-triazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2,4,6,12,14,16-heptaen-8-one	Investigative	46225750	C15H11N3O	249.27	CC1=CC=CC2=NC3=C(N12)NC(=O)C4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BPS83V	4-[4-[(2,8-Dimethyl-3-oxo-4H-1,4-benzoxazin-6-yl)methyl]piperazin-1-yl]-N-methylbenzamide	Investigative	66716783	C23H28N4O3	408.5	CC1C(=O)NC2=C(O1)C(=CC(=C2)CN3CCN(CC3)C4=CC=C(C=C4)C(=O)NC)C	EC50 = 75000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BQ0PB5	(5Z)-5-[[1-[(4-Chlorophenyl)methyl]indol-3-yl]methylidene]-1,3-thiazolidine-2,4-dione	Investigative	18973566	C19H13ClN2O2S	368.8	C1=CC=C2C(=C1)C(=CN2CC3=CC=C(C=C3)Cl)/C=C\\4/C(=O)NC(=O)S4	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BQAE41	4-[[3-(2-Amino-5-azatricyclo[6.3.1.04,12]dodeca-1(11),8(12),9-triene-5-carbonyl)-4-fluorophenyl]methyl]-2H-phthalazin-1-one	Investigative	71604869	C27H23FN4O2	454.5	C1CN(C2CC(C3=CC=CC1=C23)N)C(=O)C4=C(C=CC(=C4)CC5=NNC(=O)C6=CC=CC=C65)F	IC50 = 76600 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BQNJ08	3-Bromo-N-[2-(2-bromo-6-methyl-3-propan-2-ylphenoxy)-5-chlorophenyl]-5-chloro-2-hydroxybenzamide	Investigative	56658116	C23H19Br2Cl2NO3	588.1	CC1=C(C(=C(C=C1)C(C)C)Br)OC2=C(C=C(C=C2)Cl)NC(=O)C3=C(C(=CC(=C3)Cl)Br)O	IC50 = 78000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BS84KD	4-(4-Carbamoylphenoxy)benzoic acid	Investigative	28825295	C14H11NO4	257.24	C1=CC(=CC=C1C(=O)N)OC2=CC=C(C=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BS9D0K	(5Z)-5-[(1-Benzylindol-3-yl)methylidene]-1,3-thiazolidine-2,4-dione	Investigative	18973266	C19H14N2O2S	334.4	C1=CC=C(C=C1)CN2C=C(C3=CC=CC=C32)/C=C\\4/C(=O)NC(=O)S4	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BSL3C5	1-[3-[4-(2-Chlorophenyl)-5-pyrimidin-4-yl-1,2,4-triazol-3-yl]cyclobutyl]-2-oxidanylidene-3~{H}-benzimidazole-5-carbonitrile	Investigative	131801402	C24H17ClN8O	468.9	C1C(CC1N2C3=C(C=C(C=C3)C#N)NC2=O)C4=NN=C(N4C5=CC=CC=C5Cl)C6=NC=NC=C6	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BSU1A2	3-(4-Methoxyphenyl)quinoline-8-carboxamide	Investigative	25208906	C17H14N2O2	278.3	COC1=CC=C(C=C1)C2=CN=C3C(=C2)C=CC=C3C(=O)N	IC50 = 62000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BT04NV	4-Amino-N-quinolin-8-ylbenzamide	Investigative	6490174	C16H13N3O	263.29	C1=CC2=C(C(=C1)NC(=O)C3=CC=C(C=C3)N)N=CC=C2	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BT9KP0	Disodium;6-oxo-5H-phenanthridine-3,8-disulfonate	Investigative	44291587	C13H7NNa2O7S2	399.3	C1=CC2=C(C=C1S(=O)(=O)[O-])C(=O)NC3=C2C=CC(=C3)S(=O)(=O)[O-].[Na+].[Na+]	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BTBF69	Chembl4129789	Investigative	133107908	C25H23FN2O3	418.5	C1CN(CCC1C2=CC=C(C=C2)F)C(=O)C3=CC(=CC=C3)OC4=CC=C(C=C4)C(=O)N	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BU26GV	7-Chloro-3,4-dihydroisoquinolin-1(2H)-one	Investigative	18672397	C9H8ClNO	181.62	C1CNC(=O)C2=C1C=CC(=C2)Cl	IC50 = 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BW6IR7	(4s)-3-{4-[6-Amino-5-(Pyrimidin-2-Yl)pyridin-3-Yl]phenyl}-5,5-Dimethyl-4-Phenyl-1,3-Oxazolidin-2-One	Investigative	72193935	C26H23N5O2	437.5	CC1([C@@H](N(C(=O)O1)C2=CC=C(C=C2)C3=CC(=C(N=C3)N)C4=NC=CC=N4)C5=CC=CC=C5)C	IC50 ~ 85000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BW7XR4	3-Bromobenzamide	Investigative	89807	C7H6BrNO	200.03	C1=CC(=CC(=C1)Br)C(=O)N	IC50 = 55000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BW97JI	3-(Dimethylamino)benzamide	Investigative	2758498	C9H12N2O	164.2	CN(C)C1=CC=CC(=C1)C(=O)N	IC50 = 120000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BWA6V5	14-Methoxy-9,11,13,17-tetrazatetracyclo[8.7.0.02,7.011,16]heptadeca-1(10),2,4,6,12,14,16-heptaen-8-one	Investigative	46225808	C14H10N4O2	266.25	COC1=CC2=NC3=C(N2C=N1)NC(=O)C4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BX6NZ3	4-[(3Ar,4r,7s,7as)-1,3-Dioxooctahydro-2h-4,7-Methanoisoindol-2-Yl]-N-(Quinolin-8-Yl)benzamide	Investigative	56587957	C25H21N3O3	411.5	C1C[C@H]2C[C@@H]1[C@@H]3[C@H]2C(=O)N(C3=O)C4=CC=C(C=C4)C(=O)NC5=CC=CC6=C5N=CC=C6	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BY3QL6	1-[4-[(4S)-5,5-Dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]cyclohexyl]-4-fluoro-2-oxo-3H-benzimidazole-5-carbonitrile	Investigative	71681330	C25H25FN4O3	448.5	CC1([C@@H](N(C(=O)O1)C2CCC(CC2)N3C4=C(C(=C(C=C4)C#N)F)NC3=O)C5=CC=CC=C5)C	IC50 ~ 85000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BYPV12	2-(4-Chlorophenyl)quinazolin-4-ol	Investigative	135404247	C14H9ClN2O	256.68	C1=CC=C2C(=C1)C(=O)NC(=N2)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	BZQ31Y	N-{4-[(2-Chlorophenyl)(Pyrimidin-4-Yl)carbamoyl]phenyl}-4-Methoxybenzamide	Investigative	105539834	C25H19ClN4O3	458.9	COC1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)C(=O)N(C3=NC=NC=C3)C4=CC=CC=C4Cl	IC50 = 77000 nM	Poor binder
T06273	Poly [ADP-ribose] polymerase 1	D00RIX	APIGENIN	Investigative	5280443	C15H10O5	270.24	C1=CC(=CC=C1C2=CC(=O)C3=C(C=C(C=C3O2)O)O)O	IC50 = 100000 nM	Poor binder