TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T06569	Carbonic anhydrase VI	D0V0UK	SULFAMIDE	Phase 1	82267	H4N2O2S	96.11	NS(=O)(=O)N	Ki = 70000 nM	Poor binder
T06569	Carbonic anhydrase VI	B3W7GJ	Hydrazoic acid	Investigative	24530	HN3	43.029	N=[N+]=[N-]	Ki = 70000 nM	Poor binder
T06569	Carbonic anhydrase VI	B4OX3Q	(E)-4-(4-Hydroxyphenyl)-1-[(2S,3R,4R,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]but-3-en-2-one	Investigative	71521576	C16H20O7	324.32	C1=CC(=CC=C1/C=C/C(=O)C[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)CO)O)O)O)O	Ki ~ 100000 nM	Poor binder
T06569	Carbonic anhydrase VI	B6Z4IJ	N,N'-Bis(2-aminoethyl)-1,3-propanediamine	Investigative	78479	C7H20N4	160.26	C(CNCCN)CNCCN	Ki = 53000 nM	Poor binder
T06569	Carbonic anhydrase VI	B86ABV	(E)-4-(4-Hydroxyphenyl)-1-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]but-3-en-2-one	Investigative	45269749	C16H20O7	324.32	C1=CC(=CC=C1/C=C/C(=O)C[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O	Ki ~ 100000 nM	Poor binder
T06569	Carbonic anhydrase VI	B8TDZ9	Spermine(hbbh)	Investigative	389642	C20H42N4O4	402.6	CC(C)(C)OC(=O)N(CCCCN(CCCN)C(=O)OC(C)(C)C)CCCN	Ki = 114000 nM	Poor binder
T06569	Carbonic anhydrase VI	BDOE45	(E)-4-(3-Hydroxyphenyl)-1-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]but-3-en-2-one	Investigative	71521496	C16H20O7	324.32	C1=CC(=CC(=C1)O)/C=C/C(=O)C[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O	Ki ~ 100000 nM	Poor binder
T06569	Carbonic anhydrase VI	BEH8D0	Hydrogen cyanide	Investigative	768	CHN	27.025	C#N	Ki = 70000 nM	Poor binder
T06569	Carbonic anhydrase VI	BFT8I4	N-[2-(Naphthalen-1-ylamino)ethyl]acetamide	Investigative	2900806	C14H16N2O	228.29	CC(=O)NCCNC1=CC=CC2=CC=CC=C21	Ki = 109000 nM	Poor binder
T06569	Carbonic anhydrase VI	BNKI43	2,3,6-Tribromo-4,5-dimethoxybenzyl alcohol	Investigative	57397664	C9H9Br3O3	404.88	COC1=C(C(=C(C(=C1Br)CO)Br)Br)OC	Ki = 158592 nM	Poor binder
T06569	Carbonic anhydrase VI	BS58HU	N1,N3-Bis(2-(2,2,2-trifluoroacetamido)ethyl)-propane-1,3-diaminium trifluoroacetate	Investigative	46899573	C11H18F6N4O2	352.28	C(CNCCNC(=O)C(F)(F)F)CNCCNC(=O)C(F)(F)F	Ki = 156000 nM	Poor binder
T06569	Carbonic anhydrase VI	BV0I2K	N1,N12-Bis(trifluoroacetyl)-N4,N8-bis(t-butoxycarbonyl)spermine	Investigative	389641	C24H40F6N4O6	594.6	CC(C)(C)OC(=O)N(CCCCN(CCCNC(=O)C(F)(F)F)C(=O)OC(C)(C)C)CCCNC(=O)C(F)(F)F	Ki = 104000 nM	Poor binder
T06569	Carbonic anhydrase VI	D00RNZ	7-(benzyloxy)-2H-chromen-2-one	Investigative	910172	C16H12O3	252.26	C1=CC=C(C=C1)COC2=CC3=C(C=C2)C=CC(=O)O3	Ki = 93100 nM	Poor binder
T06569	Carbonic anhydrase VI	D00XJA	6-methoxy-2-oxo-2H-chromene-3-carboxylic acid	Investigative	711717	C11H8O5	220.18	COC1=CC2=C(C=C1)OC(=O)C(=C2)C(=O)O	Ki = 65200 nM	Poor binder
T06569	Carbonic anhydrase VI	D01BUB	2,5-difluorophenol	Investigative	94952	C6H4F2O	130.09	C1=CC(=C(C=C1F)O)F	Ki = 90600 nM	Poor binder
T06569	Carbonic anhydrase VI	D05VSK	ETHOXYCOUMARIN	Investigative	35703	C11H10O3	190.19	CCOC1=CC2=C(C=C1)C=CC(=O)O2	Ki = 82300 nM	Poor binder
T06569	Carbonic anhydrase VI	D0EJ9B	Phenyl Boronic acid	Investigative	66827	C6H7BO2	121.93	B(C1=CC=CC=C1)(O)O	Ki ~ 50000 nM	Poor binder
T06569	Carbonic anhydrase VI	D0G3BI	6-methyl-2-oxo-2H-chromene-3-carboxylic acid	Investigative	25090	C11H8O4	204.18	CC1=CC2=C(C=C1)OC(=O)C(=C2)C(=O)O	Ki = 54700 nM	Poor binder
T06569	Carbonic anhydrase VI	D0H3NS	2-oxo-2H-chromene-3-carboxylic acid	Investigative	10752	C10H6O4	190.15	C1=CC=C2C(=C1)C=C(C(=O)O2)C(=O)O	Ki = 76300 nM	Poor binder