TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T08856	Matrix metalloproteinase-8	B01JWL	N-((S)-2-Benzyloxy-1-dimethylcarbamoyl-propyl)-N''-hydroxy-oxalamide	Investigative	44384146	C15H21N3O5	323.34	CC([C@@H](C(=O)N(C)C)NC(=O)C(=O)NO)OCC1=CC=CC=C1	Ki = 75000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B0GWI6	2-[(4-Methoxyphenyl)methylthio]-6-methyl-1H-pyrimidin-4-one	Investigative	135438809	C13H14N2O2S	262.33	CC1=CC(=O)NC(=N1)SCC2=CC=C(C=C2)OC	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B0HJ9Y	[Phosphono-[4-(trifluoromethyl)anilino]methyl]phosphonic acid	Investigative	72204931	C8H10F3NO6P2	335.11	C1=CC(=CC=C1C(F)(F)F)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B0X7FC	Ethyl 2-benzyl-3-(hydroxyamino)-3-oxopropanoate	Investigative	10728558	C12H15NO4	237.25	CCOC(=O)C(CC1=CC=CC=C1)C(=O)NO	Ki = 52480.75 nM	Poor binder
T08856	Matrix metalloproteinase-8	B25XRZ	Cyclohexanamine;3-methylbutylcarbamoylphosphonic acid	Investigative	9817594	C12H27N2O4P	294.33	CC(C)CCNC(=O)P(=O)(O)O.C1CCC(CC1)N	IC50 = 50000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B2APB0	(R)-2-(N-((2-Fluoropyridin-3-yl)methyl)-4-methoxyphenylsulphonamido)-3-methylbutanoic acid	Investigative	23657695	C18H21FN2O5S	396.4	CC(C)[C@H](C(=O)O)N(CC1=C(N=CC=C1)F)S(=O)(=O)C2=CC=C(C=C2)OC	IC50 = 78000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B3EUN1	[(3-Fluoroanilino)-phosphonomethyl]phosphonic acid	Investigative	72205111	C7H10FNO6P2	285.1	C1=CC(=CC(=C1)F)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B3FI7C	N-Hydroxybenzenesulfonamide	Investigative	69033	C6H7NO3S	173.19	C1=CC=C(C=C1)S(=O)(=O)NO	Ki = 74000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B3S5OF	4-Chloro-N-hydroxybenzene-1-sulfonamide	Investigative	352863	C6H6ClNO3S	207.64	C1=CC(=CC=C1S(=O)(=O)NO)Cl	Ki = 70000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B3T2HA	Chembl4215193	Investigative	145972073	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B3TM2X	[(2,4-Dichloroanilino)-phosphono-methyl]phosphonic acid	Investigative	5276565	C7H9Cl2NO6P2	336	C1=CC(=C(C=C1Cl)Cl)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B3Z2SA	N-((R)-1-Benzylcarbamoyl-ethyl)-N''-hydroxy-2-isobutyl-malonamide	Investigative	10544776	C17H25N3O4	335.4	C[C@H](C(=O)NCC1=CC=CC=C1)NC(=O)C(CC(C)C)C(=O)NO	Ki = 194000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B43XGE	Chembl4211708	Investigative	145964366	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=CC=C7OC	IC50 = 52500 nM	Poor binder
T08856	Matrix metalloproteinase-8	B4FXQ5	N*1*-Benzyl-2-(2-hydroxycarbamoyl-4-methyl-pentanoylamino)-succinamide	Investigative	44343240	C18H26N4O5	378.4	CC(C)CC(C(=O)NC(CC(=O)N)C(=O)NCC1=CC=CC=C1)C(=O)NO	Ki = 55000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B4MKA1	N-(p-Fluorobenzenesulfonyl)hydroxylamine	Investigative	12635074	C6H6FNO3S	191.18	C1=CC(=CC=C1F)S(=O)(=O)NO	Ki = 75000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B52MUV	(5S)-4-[2-(1-Adamantyl)ethyl]-5-butyl-1-[(2S)-1-(4-hydroxyphenyl)-3-[(2S)-2-[[(6R)-6-(naphthalen-2-ylmethyl)-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]piperazine-2,3-dione	Investigative	122181996	C49H63N5O5	802.1	CCCC[C@H]1CN(C(=O)C(=O)N1CCC23CC4CC(C2)CC(C4)C3)[C@@H](CC5=CC=C(C=C5)O)CN6CCC[C@H]6CN7[C@@H](CNC(=O)C7=O)CC8=CC9=CC=CC=C9C=C8	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B5AB4X	(Propylamino)carbonylphosphonic acid	Investigative	11400989	C4H10NO4P	167.1	CCCNC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B61DLV	[(4-Cyanoanilino)-phosphonomethyl]phosphonic acid	Investigative	72204932	C8H10N2O6P2	292.12	C1=CC(=CC=C1C#N)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B6HQO3	(Diethylamino)carbonylphosphonic acid	Investigative	12671872	C5H12NO4P	181.13	CCN(CC)C(=O)P(=O)(O)O	IC50 = 70000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B6IN8S	Sodium hydrogen (butylamino)carbonylphosphonate	Investigative	23692637	C5H11NNaO4P	203.11	CCCCNC(=O)P(=O)(O)[O-].[Na+]	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B6O4DQ	(E)-N-Hydroxy-3-[4-(trifluoromethyl)phenyl]acrylamide	Investigative	53374826	C10H8F3NO2	231.17	C1=CC(=CC=C1/C=C/C(=O)NO)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B6QZN9	Chembl4214716	Investigative	145971807	C50H52Cl2F2N4O5S	929.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=C(C=C5)F)Cl)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=C(C=C7)F)Cl	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B6W3HR	Chembl4202989	Investigative	145978450	C35H41BrN2O5S	681.7	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5Br)C)S(=O)(=O)O	IC50 = 84000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B7L5OB	4-Bromo-N-hydroxybenzenesulfonamide	Investigative	121255	C6H6BrNO3S	252.09	C1=CC(=CC=C1S(=O)(=O)NO)Br	Ki = 69000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B7L6VX	Chembl4160618	Investigative	145956426	C11H13N3O7S	331.3	C1=CC(=CC=C1[N+](=O)[O-])S(=O)(=O)N[C@@H](CCC(=O)N)C(=O)O	IC50 = 198900 nM	Poor binder
T08856	Matrix metalloproteinase-8	B7POG6	N-(1-Benzylcarbamoyl-ethyl)-N''-hydroxy-2-isobutyl-malonamide	Investigative	44343258	C17H25N3O4	335.4	CC(C)CC(C(=O)NC(C)C(=O)NCC1=CC=CC=C1)C(=O)NO	Ki = 50000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B7QJE6	Schembl21751149	Investigative	78426757	C48H59N5O5	786	C1C[C@H](N(C1)C[C@H](CC2=CC=CC=C2)N3C[C@@H](N(C(=O)C3=O)CCC45CC6CC(C4)CC(C6)C5)CC7=CC=C(C=C7)O)CN8[C@H](CNC(=O)C8=O)CC9=CC=CC=C9	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B7UZR2	Chembl4212449	Investigative	145964617	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=CC=C7F	IC50 = 64500 nM	Poor binder
T08856	Matrix metalloproteinase-8	B7ZAP0	5-Hydroxy-5-[2-(4-nitrophenyl)-2-oxoethyl]-1,3-diazinane-2,4,6-trione	Investigative	71454740	C12H9N3O7	307.22	C1=CC(=CC=C1C(=O)CC2(C(=O)NC(=O)NC2=O)O)[N+](=O)[O-]	IC50 = 63000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B86BFX	N-[(Hydroxyamino)carbonyl]-D-leucyl-Lphenylalanine methylamide	Investigative	24881245	C17H26N4O4	350.4	CC(C)C[C@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC)NC(=O)NO	IC50 = 150000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B87DNV	(Hydroxyamino)(4-iodophenyl)sulfone	Investigative	5220706	C6H6INO3S	299.09	C1=CC(=CC=C1S(=O)(=O)NO)I	Ki = 71000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B93YZI	1-(2-Hydroxycarbamoyl-4-methyl-pentanoyl)-pyrrolidine-2-carboxylic acid benzylamide	Investigative	44343397	C19H27N3O4	361.4	CC(C)CC(C(=O)NO)C(=O)N1CCCC1C(=O)NCC2=CC=CC=C2	Ki = 168000 nM	Poor binder
T08856	Matrix metalloproteinase-8	B9Q2PE	(Dibutylamino)carbonylphosphonic acid	Investigative	11207122	C9H20NO4P	237.23	CCCCN(CCCC)C(=O)P(=O)(O)O	IC50 = 90000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BA3M4C	N-[(Hydroxyamino)carbonyl]-L-leucyl-Lphenylalanine methylamide	Investigative	24881246	C17H26N4O4	350.4	CC(C)C[C@@H](C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NC)NC(=O)NO	IC50 = 70000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BAJ49I	(1-Benzyloxycarbonylamino-2-phenyl-ethyl)-[2-[1-carbamoyl-2-(1H-indol-3-yl)-ethylcarbamoyl]-3-(2-trifluoromethoxy-phenylsulfanyl)-propyl]-phosphinic acid	Investigative	44341652	C38H38F3N4O7PS	782.8	C1=CC=C(C=C1)CC(NC(=O)OCC2=CC=CC=C2)P(=O)(CC(CSC3=CC=CC=C3OC(F)(F)F)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)N)O	Ki = 200000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BAN7Z4	(Cycloheptylamino)carbonylphosphonic acid	Investigative	11447356	C8H16NO4P	221.19	C1CCCC(CC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BB5SG2	(5S)-4-[2-(1-Adamantyl)ethyl]-5-[(4-hydroxyphenyl)methyl]-1-[(2R)-1-[(2S)-2-[[(6R)-6-[(4-hydroxyphenyl)methyl]-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-naphthalen-2-ylpropan-2-yl]piperazine-2,3-dione	Investigative	122181997	C52H61N5O6	852.1	C1C[C@H](N(C1)C[C@@H](CC2=CC3=CC=CC=C3C=C2)N4C[C@@H](N(C(=O)C4=O)CCC56CC7CC(C5)CC(C7)C6)CC8=CC=C(C=C8)O)CN9[C@@H](CNC(=O)C9=O)CC1=CC=C(C=C1)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BBM0L7	(3-Bromophenylamino)Methylenediphosphonic Acid	Investigative	5277481	C7H10BrNO6P2	346.01	C1=CC(=CC(=C1)Br)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BBY86P	Benzenemethanesulfonamide, N-hydroxy-	Investigative	23645541	C7H9NO3S	187.22	C1=CC=C(C=C1)CS(=O)(=O)NO	Ki = 76000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BC6T0Q	(5S)-5-Benzyl-1-[(2R)-1-[(2S)-2-[[(6R)-6-benzyl-2,3-dioxopiperazin-1-yl]methyl]pyrrolidin-1-yl]-3-cyclohexylpropan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181999	C44H55N5O4	717.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=CC=C7	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BCIL03	(Hydroxysulfamoyl)dimethylamine	Investigative	12447203	C2H8N2O3S	140.16	CN(C)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BD1RQ4	Chembl4206821	Investigative	145978127	C35H42N2O5S	602.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5)C)S(=O)(=O)O	IC50 = 89300 nM	Poor binder
T08856	Matrix metalloproteinase-8	BD36TG	Chembl4203061	Investigative	145977013	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)F	IC50 = 92100 nM	Poor binder
T08856	Matrix metalloproteinase-8	BD57BI	Chembl4211700	Investigative	145963891	C36H44N2O6S	632.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)O	IC50 = 90200 nM	Poor binder
T08856	Matrix metalloproteinase-8	BDP5Z6	Chembl4211258	Investigative	145966420	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)OC)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)OC	IC50 = 76500 nM	Poor binder
T08856	Matrix metalloproteinase-8	BDXN08	Cyclohexylmethylcarbamoylphosphonic Acid	Investigative	11470070	C8H16NO4P	221.19	C1CCC(CC1)CNC(=O)P(=O)(O)O	IC50 = 80000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BF0D9I	[Anilino(phosphono)methyl]phosphonic acid	Investigative	450256	C7H11NO6P2	267.11	C1=CC=C(C=C1)NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BFH2P0	[2-Methyl-1-[[4-(5-methylthiophen-2-yl)phenyl]sulfonylamino]propyl]phosphonic acid	Investigative	127029508	C15H20NO5PS2	389.4	CC1=CC=C(S1)C2=CC=C(C=C2)S(=O)(=O)NC(C(C)C)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BGF30U	(2R)-N-Hydroxy-2-[[1-[2-[2-[2-[2-[4-[[[(2R)-1-(hydroxyamino)-3-methyl-1-oxobutan-2-yl]-(4-methoxyphenyl)sulfonylamino]methyl]triazol-1-yl]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methyl-(4-methoxyphenyl)sulfonylamino]-3-methylbutanamide	Investigative	70692916	C38H56N10O13S2	925	CC(C)[C@H](C(=O)NO)N(CC1=CN(N=N1)CCOCCOCCOCCN2C=C(N=N2)CN([C@H](C(C)C)C(=O)NO)S(=O)(=O)C3=CC=C(C=C3)OC)S(=O)(=O)C4=CC=C(C=C4)OC	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BGN3P0	2-(2-(4-Methoxyphenylsulfonyl)phenyl)acetic Acid	Investigative	44479700	C15H14O5S	306.3	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2CC(=O)O	IC50 = 74000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BGPR53	N-Hydroxy-4-methylbenzenesulfonamide	Investigative	10081163	C7H9NO3S	187.22	CC1=CC=C(C=C1)S(=O)(=O)NO	Ki = 64000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BGY1M0	1-[2-[4-(4-Cyanophenyl)phenoxy]ethyl]-3-hydroxyurea	Investigative	44286483	C16H15N3O3	297.31	C1=CC(=CC=C1C#N)C2=CC=C(C=C2)OCCNC(=O)NO	IC50 ~ 120000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BH5V7X	[(4-Hydroxyanilino)-phosphonomethyl]phosphonic acid	Investigative	72204933	C7H11NO7P2	283.11	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BHR8Z5	Chembl4211189	Investigative	145964116	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)F)C)S(=O)(=O)O	IC50 = 77400 nM	Poor binder
T08856	Matrix metalloproteinase-8	BI2GT9	2-Benzyl-N-hydroxy-3-morpholino-3-oxopropanamide	Investigative	10540548	C14H18N2O4	278.3	C1COCCN1C(=O)C(CC2=CC=CC=C2)C(=O)NO	Ki = 50000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BI7Y5L	1,1,1-Trifluoro-N-hydroxymethanesulfonamide	Investigative	23644662	CH2F3NO3S	165.09	C(F)(F)(F)S(=O)(=O)NO	Ki ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BI8BQ6	Cyclohexylcarbamoylphosphonic Acid	Investigative	9837496	C7H14NO4P	207.16	C1CCC(CC1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BIBX94	CID 78426619	Investigative	78426619	C44H55N5O5	733.9	C1CCC(CC1)C[C@H](CN2CCC[C@H]2CN3[C@H](CNC(=O)C3=O)CC4=CC=CC=C4)N5C[C@@H](N(C(=O)C5=O)CCC6=CC=CC=C6)CC7=CC=C(C=C7)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BJ1LV0	(5S)-5-Benzyl-1-[(2R)-1-cyclohexyl-3-[(2S)-2-[[(6S)-2,3-dioxo-6-propylpiperazin-1-yl]methyl]pyrrolidin-1-yl]propan-2-yl]-4-(2-phenylethyl)piperazine-2,3-dione	Investigative	122181998	C40H55N5O4	669.9	CCC[C@H]1CNC(=O)C(=O)N1C[C@@H]2CCCN2C[C@@H](CC3CCCCC3)N4C[C@@H](N(C(=O)C4=O)CCC5=CC=CC=C5)CC6=CC=CC=C6	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BJ5Y9M	Ethyl 3-(hydroxyamino)-3-oxo-2-phenylpropanoate	Investigative	10775444	C11H13NO4	223.22	CCOC(=O)C(C1=CC=CC=C1)C(=O)NO	Ki = 97723.72 nM	Poor binder
T08856	Matrix metalloproteinase-8	BJ76ZM	Chembl4206886	Investigative	145976412	C50H56N4O5S	825.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=CC=C7	IC50 = 52500 nM	Poor binder
T08856	Matrix metalloproteinase-8	BJ8Y6K	[1-[[4-(6-Fluoropyridin-3-yl)phenyl]sulfonylamino]-2-methylpropyl]phosphonic acid	Investigative	127029507	C15H18FN2O5PS	388.4	CC(C)C(NS(=O)(=O)C1=CC=C(C=C1)C2=CN=C(C=C2)F)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BJI49R	Chembl4202455	Investigative	145977231	C35H41FN2O5S	620.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5F)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BJK4U1	Chembl4202528	Investigative	145976230	C50H54Br2N4O5S	982.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)Br)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)Br	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BJZL58	4-Chloroanilinomethylenebisphosphonic acid	Investigative	15629940	C7H10ClNO6P2	301.56	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)Cl	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BK16HW	(Sec-butylamino)carbonylphosphonic acid	Investigative	11286824	C5H12NO4P	181.13	CCC(C)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BK3AN4	N-Benzyl-3-(2-hydroxycarbamoyl-4-methyl-pentanoylamino)-succinamic acid	Investigative	44343404	C18H25N3O6	379.4	CC(C)CC(C(=O)NC(CC(=O)O)C(=O)NCC1=CC=CC=C1)C(=O)NO	Ki = 88000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BK3M2U	Chembl4211771	Investigative	145967177	C50H54Br2N4O5S	982.9	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)Br)C)S(=O)(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)Br	IC50 = 87500 nM	Poor binder
T08856	Matrix metalloproteinase-8	BK5X2A	[(4-Fluoro-3-nitroanilino)-phosphonomethyl]phosphonic acid	Investigative	72205112	C7H9FN2O8P2	330.1	C1=CC(=C(C=C1NC(P(=O)(O)O)P(=O)(O)O)[N+](=O)[O-])F	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BKI10F	2-[(4-Chlorophenyl)methylthio]-1,5,6,7-tetrahydrocyclopenta[d]pyrimidin-4-one	Investigative	135412054	C14H13ClN2OS	292.8	C1CC2=C(C1)N=C(NC2=O)SCC3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BKP74E	2-Hydroxycarbamoyl-4-methyl-pentanoic acid ethyl ester	Investigative	10584303	C9H17NO4	203.24	CCOC(=O)C(CC(C)C)C(=O)NO	Ki = 190000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BKPV14	N-Hydroxy-N-{1-(1-isobutyl-piperidin-4-ylidenemethyl)-2-[4-(2-methyl-quinolin-4-ylmethoxy)-benzenesulfonyl]-ethyl}-formamide	Investigative	44330147	C30H37N3O5S	551.7	CC1=NC2=CC=CC=C2C(=C1)COC3=CC=C(C=C3)S(=O)(=O)CC(C=C4CCN(CC4)CC(C)C)N(C=O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BLF1I4	Chembl4207344	Investigative	145975699	C36H44N2O6S	632.8	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5OC)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BMLF38	N-[(2r)-2-(Hydroxycarbamoyl)-4-Methylpentanoyl]-L-Alanylglycinamide	Investigative	5496618	C12H22N4O5	302.33	C[C@@H](C(=O)NCC(=O)N)NC(=O)[C@H](CC(C)C)C(=O)NO	Ki = 121000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BND24P	Ethyl 2-(hydroxycarbamoyl)-3-methylbutanoate	Investigative	44445914	C8H15NO4	189.21	CCOC(=O)C(C(C)C)C(=O)NO	Ki = 190546.07 nM	Poor binder
T08856	Matrix metalloproteinase-8	BNH40K	trans-2-Aminocyclohexylcarbamoylphosphonic acid	Investigative	24807817	C7H15N2O4P	222.18	C1CC[C@H]([C@@H](C1)N)NC(=O)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BO2H4C	[1-[[4-[5-(Methoxymethyl)thiophen-2-yl]phenyl]sulfonylamino]-2-methylpropyl]phosphonic acid	Investigative	127029510	C16H22NO6PS2	419.5	CC(C)C(NS(=O)(=O)C1=CC=C(C=C1)C2=CC=C(S2)COC)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BOC1P3	[(3-Nitroanilino)-phosphono-methyl]phosphonic acid	Investigative	5277490	C7H10N2O8P2	312.11	C1=CC(=CC(=C1)[N+](=O)[O-])NC(P(=O)(O)O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BQXF82	Ethyl 2-(hydroxycarbamoyl)-4-phenylbutanoate	Investigative	10800736	C13H17NO4	251.28	CCOC(=O)C(CCC1=CC=CC=C1)C(=O)NO	Ki = 189000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BR28PO	Chembl4163839	Investigative	145959777	C18H19N3O7S	421.4	C1=CC=C(C=C1)CNC(=O)CC[C@@H](C(=O)O)NS(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-]	IC50 = 172800 nM	Poor binder
T08856	Matrix metalloproteinase-8	BSRZ86	Cyclopentylcarbamoylphosphonic Acid	Investigative	10198038	C6H12NO4P	193.14	C1CCC(C1)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BT16SP	Benzyl 6-Benzyl-5,7-Dioxo-6,7-Dihydro-5h-[1,3]thiazolo[3,2-C]pyrimidine-2-Carboxylate	Investigative	9896504	C21H16N2O4S	392.4	C1=CC=C(C=C1)CN2C(=O)C=C3N(C2=O)C=C(S3)C(=O)OCC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BT17QX	Lithium ethyl (cyclohexylamino)carbonylphosphonate	Investigative	53322469	C9H17LiNO4P	241.2	[Li+].CCOP(=O)(C(=O)NC1CCCCC1)[O-]	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BT61GW	4-{[1-Methyl-2,4-Dioxo-6-(3-Phenylprop-1-Yn-1-Yl)-1,4-Dihydroquinazolin-3(2h)-Yl]methyl}benzoic Acid	Investigative	10224181	C26H20N2O4	424.4	CN1C2=C(C=C(C=C2)C#CCC3=CC=CC=C3)C(=O)N(C1=O)CC4=CC=C(C=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BUO20M	[Phosphono-[3-(trifluoromethyl)anilino]methyl]phosphonic acid	Investigative	72204934	C8H10F3NO6P2	335.11	C1=CC(=CC(=C1)NC(P(=O)(O)O)P(=O)(O)O)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BUX9C2	Chembl4218730	Investigative	145969859	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)OC)C)S(=O)(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)OC	IC50 = 55100 nM	Poor binder
T08856	Matrix metalloproteinase-8	BV1HA4	Hydroxysulfonamide 48	Investigative	23644663	CH2Cl3NO3S	214.5	C(S(=O)(=O)NO)(Cl)(Cl)Cl	Ki ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BVAB51	Chembl4214656	Investigative	145972990	C35H41BrN2O5S	681.7	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=CC=C5Br)C)S(=O)(=O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BVZ90P	(Isopropylamino)carbonylphosphonic acid	Investigative	11147931	C4H10NO4P	167.1	CC(C)NC(=O)P(=O)(O)O	IC50 = 50000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BWP2L8	Chembl4210975	Investigative	145966162	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@@H](CC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)OC)C)S(=O)(=O)N[C@@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)OC	IC50 = 52100 nM	Poor binder
T08856	Matrix metalloproteinase-8	BWY4L8	Chembl4203717	Investigative	145976282	C52H60N4O7S	885.1	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC=C(C=C5)OC)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC=C(C=C7)OC	IC50 = 56100 nM	Poor binder
T08856	Matrix metalloproteinase-8	BX1NG5	Phenethylcarbamoylphosphonic Acid	Investigative	9794947	C9H12NO4P	229.17	C1=CC=C(C=C1)CCNC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BX35SB	Chembl4207416	Investigative	145978615	C50H54F2N4O5S	861	CC(C)C1=C(C=C2C(=C1)CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)N[C@H](CC4=CC=CC=C4)C(=O)NC5=CC(=CC=C5)F)C)S(=O)(=O)N[C@H](CC6=CC=CC=C6)C(=O)NC7=CC(=CC=C7)F	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BXUF15	(R)-2-(4-Fluorophenylsulphonamido-N-(pyridin-3-ylmethyl))-3-methylbutanoic acid	Investigative	23655714	C17H19FN2O4S	366.4	CC(C)[C@H](C(=O)O)N(CC1=CN=CC=C1)S(=O)(=O)C2=CC=C(C=C2)F	IC50 = 71000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BY8QH0	Piperidin-1-ylcarbonylphosphonic acid	Investigative	44328155	C6H12NO4P	193.14	C1CCN(CC1)C(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BZP8X7	[(4-Fluoroanilino)-phosphonomethyl]phosphonic acid	Investigative	72204928	C7H10FNO6P2	285.1	C1=CC(=CC=C1NC(P(=O)(O)O)P(=O)(O)O)F	IC50 ~ 100000 nM	Poor binder
T08856	Matrix metalloproteinase-8	BZWU56	[(Naphthalen-1-ylamino)-phosphonomethyl]phosphonic acid	Investigative	19382975	C11H13NO6P2	317.17	C1=CC=C2C(=C1)C=CC=C2NC(P(=O)(O)O)P(=O)(O)O	IC50 = 61000 nM	Poor binder
T08856	Matrix metalloproteinase-8	D09USO	(biphenyl-3-ylamino)methylenediphosphonic acid	Investigative	5277466	C13H15NO6P2	343.21	C1=CC=C(C=C1)C2=CC(=CC=C2)NC(P(=O)(O)O)P(=O)(O)O	IC50 = 52000 nM	Poor binder
T08856	Matrix metalloproteinase-8	D0A0FY	N-Hydroxy-2-(4-methoxy-benzenesulfonyl)benzamide	Investigative	44479457	C14H13NO5S	307.32	COC1=CC=C(C=C1)S(=O)(=O)C2=CC=CC=C2C(=O)NO	IC50 = 72000 nM	Poor binder
T08856	Matrix metalloproteinase-8	D0T1FR	Cis-2-aminocyclohexylcarbamoylphosphonic acid	Investigative	44457233	C7H15N2O4P	222.18	C1CC[C@H]([C@H](C1)N)NC(=O)P(=O)(O)O	IC50 ~ 100000 nM	Poor binder