TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T10191	T-cell surface glycoprotein CD4	B1IA8R	5-[1-[3-Carboxy-4-[[4-(4-carboxyphenyl)phenyl]methoxy]-5-chlorophenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-2-[[4-(4-carboxyphenyl)phenyl]methoxy]-3-chlorobenzoic acid	Investigative	76325926	C73H80Cl2O10	1188.3	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCC=C(C5=CC(=C(C(=C5)Cl)OCC6=CC=C(C=C6)C7=CC=C(C=C7)C(=O)O)C(=O)O)C8=CC(=C(C(=C8)Cl)OCC9=CC=C(C=C9)C1=CC=C(C=C1)C(=O)O)C(=O)O)C)C	EC50 ~ 100000 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	B1J9LA	5-[1-[3-Carboxy-4-[[4-(3-carboxyphenyl)phenyl]methoxy]-5-chlorophenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-2-[[4-(3-carboxyphenyl)phenyl]methoxy]-3-chlorobenzoic acid	Investigative	76311397	C73H80Cl2O10	1188.3	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCC=C(C5=CC(=C(C(=C5)Cl)OCC6=CC=C(C=C6)C7=CC(=CC=C7)C(=O)O)C(=O)O)C8=CC(=C(C(=C8)Cl)OCC9=CC=C(C=C9)C1=CC(=CC=C1)C(=O)O)C(=O)O)C)C	EC50 ~ 95000 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	B5YAW6	5-[1-[3-Carboxy-4-[[4-(carboxymethyl)phenyl]methoxy]-5-chlorophenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-2-[[4-(carboxymethyl)phenyl]methoxy]-3-chlorobenzoic acid	Investigative	76333121	C63H76Cl2O10	1064.2	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCC=C(C5=CC(=C(C(=C5)Cl)OCC6=CC=C(C=C6)CC(=O)O)C(=O)O)C7=CC(=C(C(=C7)Cl)OCC8=CC=C(C=C8)CC(=O)O)C(=O)O)C)C	EC50 = 83800 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	BGZA87	(2S)-2-[[3-Chloro-5-[1-[3-chloro-5-[[(1S)-1,3-dicarboxypropyl]carbamoyl]-4-hydroxyphenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]butyl]-2-hydroxybenzoyl]amino]pentanedioic acid	Investigative	76315000	C55H76Cl2N2O12	1028.099	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCCC(C5=CC(=C(C(=C5)Cl)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O)C6=CC(=C(C(=C6)Cl)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O)C)C	EC50 = 73000 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	BH8YF0	(2S)-2-[[5-[1-[3-[[(1S)-1-Carboxy-3-methylbutyl]carbamoyl]-5-chloro-4-hydroxyphenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-3-chloro-2-hydroxybenzoyl]amino]-4-methylpentanoic acid	Investigative	76322266	C57H82Cl2N2O8	994.2	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCC=C(C5=CC(=C(C(=C5)Cl)O)C(=O)N[C@@H](CC(C)C)C(=O)O)C6=CC(=C(C(=C6)Cl)O)C(=O)N[C@@H](CC(C)C)C(=O)O)C)C	EC50 ~ 125000 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	BIG4S3	2-[[5-[1-[3-(Carboxymethylcarbamoyl)-5-chloro-4-hydroxyphenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]butyl]-3-chloro-2-hydroxybenzoyl]amino]acetic acid	Investigative	76336736	C49H68Cl2N2O8	884	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCCC(C5=CC(=C(C(=C5)Cl)O)C(=O)NCC(=O)O)C6=CC(=C(C(=C6)Cl)O)C(=O)NCC(=O)O)C)C	EC50 ~ 125000 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	BLI0R3	(2S)-2-[[5-[1-[3-[[(1S)-1-Carboxy-2-phenylethyl]carbamoyl]-5-chloro-4-hydroxyphenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-3-chloro-2-hydroxybenzoyl]amino]-3-phenylpropanoic acid	Investigative	76329481	C63H78Cl2N2O8	1062.2	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCC=C(C5=CC(=C(C(=C5)Cl)O)C(=O)N[C@@H](CC6=CC=CC=C6)C(=O)O)C7=CC(=C(C(=C7)Cl)O)C(=O)N[C@@H](CC8=CC=CC=C8)C(=O)O)C)C	EC50 ~ 62000 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	BMR20Z	(2S)-2-[[3-Chloro-5-[1-[3-chloro-5-[[(1S)-1,3-dicarboxypropyl]carbamoyl]-4-hydroxyphenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-2-hydroxybenzoyl]amino]pentanedioic acid	Investigative	76329500	C55H74Cl2N2O12	1026.099	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCC=C(C5=CC(=C(C(=C5)Cl)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O)C6=CC(=C(C(=C6)Cl)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O)C)C	EC50 = 69600 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	BOR43M	2-[[5-[1-[3-(Carboxymethylcarbamoyl)-5-chloro-4-hydroxyphenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-3-chloro-2-hydroxybenzoyl]amino]acetic acid	Investigative	76322249	C49H66Cl2N2O8	882	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCC=C(C5=CC(=C(C(=C5)Cl)O)C(=O)NCC(=O)O)C6=CC(=C(C(=C6)Cl)O)C(=O)NCC(=O)O)C)C	EC50 ~ 125000 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	BTJM67	5-[1-[3-Carboxy-4-[[4-(2-carboxyphenyl)phenyl]methoxy]-5-chlorophenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-2-[[4-(2-carboxyphenyl)phenyl]methoxy]-3-chlorobenzoic acid	Investigative	76318655	C73H80Cl2O10	1188.3	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCC=C(C5=CC(=C(C(=C5)Cl)OCC6=CC=C(C=C6)C7=CC=CC=C7C(=O)O)C(=O)O)C8=CC(=C(C(=C8)Cl)OCC9=CC=C(C=C9)C1=CC=CC=C1C(=O)O)C(=O)O)C)C	EC50 ~ 125000 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	BTNP16	5-[1-[3-Carboxy-4-[(4-carboxyphenyl)methoxy]-5-chlorophenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]butyl]-2-[(4-carboxyphenyl)methoxy]-3-chlorobenzoic acid	Investigative	76315003	C61H74Cl2O10	1038.099	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCCC(C5=CC(=C(C(=C5)Cl)OCC6=CC=C(C=C6)C(=O)O)C(=O)O)C7=CC(=C(C(=C7)Cl)OCC8=CC=C(C=C8)C(=O)O)C(=O)O)C)C	EC50 = 70400 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	BWQY20	5-[1-[3-Carboxy-5-[(3-carboxy-4-methoxybenzoyl)amino]-4-methoxyphenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-3-[(3-carboxy-4-methoxybenzoyl)amino]-2-methoxybenzoic acid	Investigative	76325920	C65H80N2O14	1113.3	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCC=C(C5=CC(=C(C(=C5)NC(=O)C6=CC(=C(C=C6)OC)C(=O)O)OC)C(=O)O)C7=CC(=C(C(=C7)NC(=O)C8=CC(=C(C=C8)OC)C(=O)O)OC)C(=O)O)C)C	EC50 ~ 66000 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	BX1QJ8	3-[[5-[1-[3-(2-Carboxyethylcarbamoyl)-5-chloro-4-hydroxyphenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-3-chloro-2-hydroxybenzoyl]amino]propanoic acid	Investigative	76311380	C51H70Cl2N2O8	910	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCC=C(C5=CC(=C(C(=C5)Cl)O)C(=O)NCCC(=O)O)C6=CC(=C(C(=C6)Cl)O)C(=O)NCCC(=O)O)C)C	EC50 = 120000 nM	Poor binder
T10191	T-cell surface glycoprotein CD4	BZY0V6	(2S)-2-[[3-Chloro-5-[1-[3-chloro-5-[[(1S)-1,2-dicarboxyethyl]carbamoyl]-4-hydroxyphenyl]-4-[(3S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-(6-methylheptan-2-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-2-hydroxybenzoyl]amino]butanedioic acid	Investigative	76325893	C53H70Cl2N2O12	998	CC(C)CCCC(C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4[C@@]3(CC[C@@H](C4)CCC=C(C5=CC(=C(C(=C5)Cl)O)C(=O)N[C@@H](CC(=O)O)C(=O)O)C6=CC(=C(C(=C6)Cl)O)C(=O)N[C@@H](CC(=O)O)C(=O)O)C)C	EC50 = 122000 nM	Poor binder