TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T11211	Androgen receptor	D0M1YR	MDV3101	Approved	15951529	C21H16F4N4O2S	464.4	CC1(C(=O)N(C(=S)N1C2=CC(=C(C=C2)C(=O)NC)F)C3=CC(=C(C=C3)C#N)C(F)(F)F)C	IC50 ~ 100000 nM	Poor binder
T11211	Androgen receptor	D0S6JG	Liothyronine	Approved	5920	C15H12I3NO4	650.97	C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)O)N)I)I)O	IC50 ~ 50000 nM	Poor binder
T11211	Androgen receptor	D0SZ1G	AZD9567	Phase 1	121248172	C27H28F2N4O3	494.5	CC(C)[C@@H]([C@@H](C1=CC=CC=C1)OC2=CC3=C(C=C2)N(N=C3)C4=CN(C(=O)C=C4)C)NC(=O)C(C)(F)F	IC50 ~ 100000 nM	Poor binder
T11211	Androgen receptor	D0DK4I	PMID26560530-Compound-24	Patented	4534	C18H22O4	302.4	CC(CC1=CC(=C(C=C1)O)O)C(C)CC2=CC(=C(C=C2)O)O	IC50 ~ 50000 nM	Poor binder
T11211	Androgen receptor	B08OGR	Ethyl 2-[2-[2-(3-ethylphenoxy)ethylsulfanyl]benzimidazol-1-yl]acetate	Investigative	71717986	C21H24N2O3S	384.5	CCC1=CC(=CC=C1)OCCSC2=NC3=CC=CC=C3N2CC(=O)OCC	IC50 = 55000 nM	Poor binder
T11211	Androgen receptor	B3IVR7	Ethyl (3aS,4S,9bS)-4-phenyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-carboxylate	Investigative	25808053	C21H21NO2	319.4	CCOC(=O)C1=CC2=C(C=C1)N[C@@H]([C@@H]3[C@@H]2C=CC3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T11211	Androgen receptor	B3PFX6	4-[2-(1H-Benzimidazol-2-ylsulfanyl)ethoxy]benzenesulfonamide	Investigative	8326955	C15H15N3O3S2	349.4	C1=CC=C2C(=C1)NC(=N2)SCCOC3=CC=C(C=C3)S(=O)(=O)N	IC50 = 62000 nM	Poor binder
T11211	Androgen receptor	B69EWK	7-Hydroxy-4-((6-methylpyridin-2-ylthio)methyl)-2H-chromen-2-one	Investigative	25225237	C16H13NO3S	299.3	CC1=NC(=CC=C1)SCC2=CC(=O)OC3=C2C=CC(=C3)O	IC50 = 50000 nM	Poor binder
T11211	Androgen receptor	B7I3QU	4-[(2,3,6-Trichlorophenyl)methyl]-2H-phthalazin-1-one	Investigative	122191907	C15H9Cl3N2O	339.6	C1=CC=C2C(=C1)C(=NNC2=O)CC3=C(C=CC(=C3Cl)Cl)Cl	IC50 = 56700 nM	Poor binder
T11211	Androgen receptor	B9D7VO	3-[1-[2-(4-Methylphenoxy)ethyl]benzimidazol-2-yl]sulfanylpropanoic acid	Investigative	2772641	C19H20N2O3S	356.4	CC1=CC=C(C=C1)OCCN2C3=CC=CC=C3N=C2SCCC(=O)O	IC50 = 50000 nM	Poor binder
T11211	Androgen receptor	B9F4BA	3-[1-(2H-1,3-Benzodioxol-5-yl)-2,5-dimethyl-1H-pyrrol-3-yl]prop-2-enoic acid	Investigative	2526709	C16H15NO4	285.29	CC1=CC(=C(N1C2=CC3=C(C=C2)OCO3)C)/C=C/C(=O)O	IC50 = 50000 nM	Poor binder
T11211	Androgen receptor	B9Y8PB	2-[(5S)-9-Fluoro-2-[4-(morpholine-4-carbonyl)phenyl]-5H-chromeno[2,3-b]pyridin-5-yl]-2-methyl-N-(1,3,4-thiadiazol-2-yl)propanamide	Investigative	118707979	C29H26FN5O4S	559.6	CC(C)([C@H]1C2=C(C(=CC=C2)F)OC3=C1C=CC(=N3)C4=CC=C(C=C4)C(=O)N5CCOCC5)C(=O)NC6=NN=CS6	Ki ~ 50000 nM	Poor binder
T11211	Androgen receptor	BARB91	Methyl 4-[(3aR,4S,9bS)-8-acetyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoate	Investigative	25764492	C22H21NO3	347.4	CC(=O)C1=CC2=C(C=C1)N[C@@H]([C@H]3[C@@H]2C=CC3)C4=CC=C(C=C4)C(=O)OC	IC50 ~ 50000 nM	Poor binder
T11211	Androgen receptor	BE2A4P	3-((2,4-Dichlorophenylthio)Methyl)Benzoate	Investigative	2566134	C14H10Cl2O2S	313.2	C1=CC(=CC(=C1)C(=O)O)CSC2=C(C=C(C=C2)Cl)Cl	IC50 = 50000 nM	Poor binder
T11211	Androgen receptor	BF15WD	N-[[(1R,4As,10aR)-1,4a-dimethyl-9-oxo-7-propan-2-yl-3,4,10,10a-tetrahydro-2H-phenanthren-1-yl]methyl]benzamide	Investigative	118717325	C27H33NO2	403.6	CC(C)C1=CC2=C(C=C1)[C@]3(CCC[C@@]([C@@H]3CC2=O)(C)CNC(=O)C4=CC=CC=C4)C	IC50 = 83800 nM	Poor binder
T11211	Androgen receptor	BF3T2G	[2-(2-p-Tolyloxy-ethylsulfanyl)-benzoimidazol-1-yl]-acetic acid	Investigative	2772706	C18H18N2O3S	342.4	CC1=CC=C(C=C1)OCCSC2=NC3=CC=CC=C3N2CC(=O)O	IC50 = 163800 nM	Poor binder
T11211	Androgen receptor	BHK38R	Chembl4174074	Investigative	145951453	C27H33NO2	403.6	CC(C)C1=CC2=C(C=C1)[C@]3(CCC[C@]([C@@H]3CC2=O)(C)CNC(=O)C4=CC=CC=C4)C	IC50 = 83800 nM	Poor binder
T11211	Androgen receptor	BJ5N0D	4-[(2,6-Dimethylphenyl)methyl]-2H-phthalazin-1-one	Investigative	122191904	C17H16N2O	264.32	CC1=C(C(=CC=C1)C)CC2=NNC(=O)C3=CC=CC=C32	IC50 = 84300 nM	Poor binder
T11211	Androgen receptor	BMGB60	4-[(2-Nitrophenyl)methyl]-2H-phthalazin-1-one	Investigative	122191896	C15H11N3O3	281.27	C1=CC=C(C(=C1)CC2=NNC(=O)C3=CC=CC=C32)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T11211	Androgen receptor	BNI97C	2-[2-(3,4-Dihydroxyphenyl)-2-oxoethyl]sulfanyl-1H-quinazolin-4-one	Investigative	135403572	C16H12N2O4S	328.3	C1=CC=C2C(=C1)C(=O)NC(=N2)SCC(=O)C3=CC(=C(C=C3)O)O	IC50 = 50000 nM	Poor binder
T11211	Androgen receptor	BTHY76	Zingerone	Investigative	31211	C11H14O3	194.23	CC(=O)CCC1=CC(=C(C=C1)O)OC	IC50 = 151356.12 nM	Poor binder
T11211	Androgen receptor	BUL5R9	(2S)-5-Amino-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[2-[[(2S,3R)-2-[[2-[[(2S)-5-amino-2-[[(2S,3S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2,4-diamino-4-oxobutanoyl]amino]pentanoyl]amino]-3-phenylpropanoyl]amino]-3-sulfanylpropanoyl]amino]-4-carboxybutanoyl]amino]-4-methylpentanoyl]amino]-3-cyclohexylpropanoyl]amino]-3-sulfanylpropanoyl]amino]-3-methylpentanoyl]amino]-5-oxopentanoyl]amino]acetyl]amino]-3-hydroxybutanoyl]amino]acetyl]amino]-3-carboxypropanoyl]amino]-3-methylbutanoyl]amino]hexanoyl]amino]propanoyl]amino]-3-sulfanylpropanoyl]amino]-4-carboxybutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-sulfanylpropanoyl]amino]-5-oxopentanoic acid	Investigative	76332910	C112H175N31O34S4	2628	CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)N)C(=O)O)NC(=O)[C@H](CS)NC(=O)[C@H](CC3CCCCC3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CS)NC(=O)[C@H](CC4=CC=CC=C4)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)N)N	Ki = 56000 nM	Poor binder
T11211	Androgen receptor	BWD3X0	1-[2-(4-Methylphenoxy)ethyl]-2-(2-phenoxyethylsulfanyl)benzimidazole	Investigative	3114779	C24H24N2O2S	404.5	CC1=CC=C(C=C1)OCCN2C3=CC=CC=C3N=C2SCCOC4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T11211	Androgen receptor	BWG5Z0	(3As,4S,9bR)-4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide	Investigative	1273173	C18H17BrN2O2S	405.3	C1C=C[C@@H]2[C@H]1[C@H](NC3=C2C=C(C=C3)S(=O)(=O)N)C4=CC=C(C=C4)Br	IC50 ~ 50000 nM	Poor binder
T11211	Androgen receptor	BX2IQ9	4-(2-Chlorobenzyl)phthalazin-1(2H)-one	Investigative	15959081	C15H11ClN2O	270.71	C1=CC=C(C(=C1)CC2=NNC(=O)C3=CC=CC=C32)Cl	IC50 = 85400 nM	Poor binder
T11211	Androgen receptor	BXIZ10	N-Carbamoyl-2-[(5S)-9-fluoro-2-[4-(morpholine-4-carbonyl)phenyl]-5H-chromeno[2,3-b]pyridin-5-yl]-2-methylpropanamide	Investigative	118707978	C28H27FN4O5	518.5	CC(C)([C@H]1C2=C(C(=CC=C2)F)OC3=C1C=CC(=N3)C4=CC=C(C=C4)C(=O)N5CCOCC5)C(=O)NC(=O)N	Ki ~ 50000 nM	Poor binder