TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T11615	Cystine/glutamate transporter	D0L4VI	L-cysteine	Clinical trial	5862	C3H7NO2S	121.16	C([C@@H](C(=O)O)N)S	Ki = 59000 nM	Poor binder
T11615	Cystine/glutamate transporter	B1EQ6U	2-Hydroxy-5-(phenylethynyl)benzoic acid	Investigative	4344716	C15H10O3	238.24	C1=CC=C(C=C1)C#CC2=CC(=C(C=C2)O)C(=O)O	IC50 = 150000 nM	Poor binder
T11615	Cystine/glutamate transporter	B59DFS	Susalimod	Investigative	3086668	C21H16N2O5S	408.4	CC1=C(N=CC=C1)NS(=O)(=O)C2=CC=C(C=C2)C#CC3=CC(=C(C=C3)O)C(=O)O	IC50 = 70000 nM	Poor binder
T11615	Cystine/glutamate transporter	B83IOK	3-[3-Carboxy-5-[2-(1-naphthyl)ethyl]isoxazole-4-yl]-L-alanine	Investigative	46200993	C19H18N2O5	354.4	C1=CC=C2C(=C1)C=CC=C2CCC3=C(C(=NO3)C(=O)O)C[C@@H](C(=O)O)N	Ki = 117000 nM	Poor binder
T11615	Cystine/glutamate transporter	BAHK49	2-Hydroxy-5-[(E)-2-[4-(pyridin-2-ylsulfamoyl)phenyl]ethenyl]benzoic acid	Investigative	19423377	C20H16N2O5S	396.4	C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)/C=C/C3=CC(=C(C=C3)O)C(=O)O	IC50 = 70000 nM	Poor binder
T11615	Cystine/glutamate transporter	BBUX73	3-[3-Carboxy-5-[2-(2-naphthyl)ethyl]isoxazole-4-yl]-L-alanine	Investigative	46229674	C19H18N2O5	354.4	C1=CC=C2C=C(C=CC2=C1)CCC3=C(C(=NO3)C(=O)O)C[C@@H](C(=O)O)N	Ki = 52000 nM	Poor binder
T11615	Cystine/glutamate transporter	BEUG91	5-(Phenylazo)salicylic acid	Investigative	76603	C13H10N2O3	242.23	C1=CC=C(C=C1)N=NC2=CC(=C(C=C2)O)C(=O)O	IC50 = 200000 nM	Poor binder
T11615	Cystine/glutamate transporter	BZ28NJ	3-[2-[4-(Pyridin-2-ylsulfamoyl)phenyl]ethynyl]benzoic acid	Investigative	56662701	C20H14N2O4S	378.4	C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)C#CC3=CC(=CC=C3)C(=O)O	IC50 = 75000 nM	Poor binder