TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T12475	Gonadotropin-releasing hormone receptor	B15JNZ	1-(2,4-Difluorobenzyl)-4-oxo-6-(methylphenethylaminomethyl)-7-(4-isobutoxyphenyl)-8-cyano-1,4-dihydropyrrolo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester	Investigative	44352608	C38H38F2N4O4	652.7	CCOC(=O)C1=CN(C2=C(C(=C(N2C1=O)CN(C)CCC3=CC=CC=C3)C4=CC=C(C=C4)OCC(C)C)C#N)CC5=C(C=C(C=C5)F)F	Ki ~ 50000 nM	Poor binder
T12475	Gonadotropin-releasing hormone receptor	B6PLW7	1-(2,4-Difluorobenzyl)-4-oxo-6-[methyl[2-(4-pyridinyl)ethyl]aminomethyl]-7-(4-isobutoxyphenyl)-8-cyano-1,4-dihydropyrrolo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester	Investigative	44352609	C37H37F2N5O4	653.7	CCOC(=O)C1=CN(C2=C(C(=C(N2C1=O)CN(C)CCC3=CC=NC=C3)C4=CC=C(C=C4)OCC(C)C)C#N)CC5=C(C=C(C=C5)F)F	Ki ~ 50000 nM	Poor binder
T12475	Gonadotropin-releasing hormone receptor	B6YRO4	1-(Cyclopropylmethyl)-4-oxo-6-[methyl[2-(2-pyridinyl)ethyl]aminomethyl]-7-(4-methoxyphenyl)-8-cyano-1,4-dihydropyrrolo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester	Investigative	44352975	C31H33N5O4	539.6	CCOC(=O)C1=CN(C2=C(C(=C(N2C1=O)CN(C)CCC3=CC=CC=N3)C4=CC=C(C=C4)OC)C#N)CC5CC5	Ki ~ 50000 nM	Poor binder
T12475	Gonadotropin-releasing hormone receptor	BS24QT	1-Benzyl-4-oxo-6-(dimethylaminomethyl)-7-(4-methoxyphenyl)-8-cyano-1,4-dihydropyrrolo[1,2-a]pyrimidine-3-carboxylic acid ethyl ester	Investigative	44352573	C28H28N4O4	484.5	CCOC(=O)C1=CN(C2=C(C(=C(N2C1=O)CN(C)C)C3=CC=C(C=C3)OC)C#N)CC4=CC=CC=C4	Ki ~ 50000 nM	Poor binder
T12475	Gonadotropin-releasing hormone receptor	BUA6Y9	3-((R)-2-Amino-2-phenyl-ethyl)-5-(2-fluoro-phenyl)-6-methyl-[1,3]oxazine-2,4-dione	Investigative	11461935	C19H17FN2O3	340.3	CC1=C(C(=O)N(C(=O)O1)C[C@@H](C2=CC=CC=C2)N)C3=CC=CC=C3F	Ki ~ 100000 nM	Poor binder