TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T12499	LCK tyrosine protein kinase	D0U3EP	Resveratrol	Phase 3	445154	C14H12O3	228.24	C1=CC(=CC=C1/C=C/C2=CC(=CC(=C2)O)O)O	IC50 = 112000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B02NLR	4-[(E)-2-(3,4-Dihydroxyphenyl)ethenyl]benzene-1,2-diol	Investigative	5468835	C14H12O4	244.24	C1=CC(=C(C=C1/C=C/C2=CC(=C(C=C2)O)O)O)O	IC50 = 74000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B0UXG5	Pinosylvin	Investigative	5280457	C14H12O2	212.24	C1=CC=C(C=C1)/C=C/C2=CC(=CC(=C2)O)O	IC50 = 193000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B0WLH8	N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide	Investigative	58056356	C17H12N4O2S	336.4	COC1=C(C=C2C=CC=NC2=C1)NC(=O)C3=CSC4=CN=CN=C43	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B0WV4G	p38 MAP Kinase Inhibitor IX	Investigative	16730109	C22H17N7O2	411.4	CC1=C(C=C(C=C1)C(=O)NC2=NOC=C2)NC3=C4C=NN(C4=NC=N3)C5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B19FQH	Chembl4166962	Investigative	142749654	C27H25Cl2N5O5	570.4	CC1=CC(=C(C=C1)OC2=NC(=NC=C2NC(=O)NC3=C(C=CC=C3Cl)Cl)NC4=CC(=CC(=C4)OC)OC)OC	IC50 = 58400 nM	Poor binder
T12499	LCK tyrosine protein kinase	B1FU8Q	2-[[2-[2-[[(2R)-2-[[(2S)-2-[4-[5-[(3As,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]butanoylamino]-3-(4-benzoylphenyl)propanoyl]amino]-3-hydroxypropanoyl]amino]ethyl-[2-(6-aminopurin-9-yl)acetyl]amino]acetyl]amino]acetic acid	Investigative	44579357	C46H57N13O11S	1000.1	C1[C@H]2[C@@H]([C@@H](S1)CCCCC(=O)NCCCC(=O)N[C@@H](CC3=CC=C(C=C3)C(=O)C4=CC=CC=C4)C(=O)N[C@H](CO)C(=O)NCCN(CC(=O)NCC(=O)O)C(=O)CN5C=NC6=C(N=CN=C65)N)NC(=O)N2	IC50 = 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B1ORS7	Chembl4163513	Investigative	142749660	C29H28Cl2N6O4	595.5	CC1=CC(=C(C=C1)OC2=NC(=NC=C2NC(=O)NC3=CC(=CC(=C3)Cl)Cl)NC4=CC=C(C=C4)N5CCOCC5)OC	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B23AEU	3-(3,5-Dibromo-4-hydroxyphenyl)-2-(3-pyridinyl)acrylonitrile	Investigative	5467801	C14H8Br2N2O	380.03	C1=CC(=CN=C1)/C(=C/C2=CC(=C(C(=C2)Br)O)Br)/C#N	IC50 = 168000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B2OQ0U	2-(2-(2-(6-Amino-9H-purin-9-yl)-N-(2-((R)-1-((S)-3-(4-benzoylphenyl)-2-(4-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)butanamido)propanoyl)pyrrolidine-2-carboxamido)ethyl)acetamido)acetamido)acetic acid	Investigative	44579359	C48H59N13O10S	1010.1	C1C[C@@H](N(C1)C(=O)[C@H](CC2=CC=C(C=C2)C(=O)C3=CC=CC=C3)NC(=O)CCCNC(=O)CCCC[C@H]4[C@@H]5[C@H](CS4)NC(=O)N5)C(=O)NCCN(CC(=O)NCC(=O)O)C(=O)CN6C=NC7=C(N=CN=C76)N	IC50 = 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B2Z1WB	5-(5,8-Dihydroxynaphthalen-2-yl)-2-hydroxybenzoic acid	Investigative	380857	C17H12O5	296.27	C1=CC2=C(C=CC(=C2C=C1C3=CC(=C(C=C3)O)C(=O)O)O)O	IC50 = 65000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B43WPI	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2R)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325478	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B4ME0H	N-(5-(Ethylcarbamoyl)-2-methylphenyl)-2-(isopropylamino)thiazole-5-carboxamide	Investigative	11439407	C17H22N4O2S	346.4	CCNC(=O)C1=CC(=C(C=C1)C)NC(=O)C2=CN=C(S2)NC(C)C	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B50FCL	6,8-Dimethyl-N-(3,4,5-trimethoxyphenyl)quinazolin-4-amine;hydrochloride	Investigative	45261968	C19H22ClN3O3	375.8	CC1=CC(=C2C(=C1)C(=NC=N2)NC3=CC(=C(C(=C3)OC)OC)OC)C.Cl	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B53UJM	(R)-2-[3-(3,4-Dihydroxy-benzyl)-ureido]-3-(3,4-dihydroxy-phenyl)-propionic acid methyl ester	Investigative	11257376	C18H20N2O7	376.4	COC(=O)[C@@H](CC1=CC(=C(C=C1)O)O)NC(=O)NCC2=CC(=C(C=C2)O)O	IC50 = 98000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B58TMC	[6-Chloro-4-methyl-3-[[3-(methylsulfamoylamino)phenyl]methyl]-2-oxochromen-7-yl] N,N-dimethylcarbamate	Investigative	24753787	C21H22ClN3O6S	479.9	CC1=C(C(=O)OC2=CC(=C(C=C12)Cl)OC(=O)N(C)C)CC3=CC(=CC=C3)NS(=O)(=O)NC	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B5F7YC	5-[(2,5-Dihydroxybenzylidene)amino]salicylic acid	Investigative	375472	C14H11NO5	273.24	C1=CC(=C(C=C1N=CC2=C(C=CC(=C2)O)O)C(=O)O)O	IC50 = 85000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B5H8JS	Chembl4164630	Investigative	145959808	C31H28F6N6O4	662.6	CC1=CC(=C(C=C1)OC2=NC(=NC=C2NC(=O)NC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)NC4=CC=C(C=C4)N5CCOCC5)OC	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B5ON0T	6-(1,9-Diazaspiro[5.5]undecan-9-Yl)-9h-Purine	Investigative	70789254	C14H20N6	272.35	C1CCNC2(C1)CCN(CC2)C3=NC=NC4=C3NC=N4	IC50 = 113000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B6PJ5F	Chembl4170806	Investigative	142749664	C29H30N4O7	546.6	CC1=CC(=C(C=C1)OC2=NC(=NC=C2NC(=O)C3=CC(=CC(=C3)OC)OC)NC4=CC(=CC(=C4)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B6X0JB	3-(3,5-Dibromo-4-hydroxyphenyl)-2-(2-pyridinyl)acrylonitrile	Investigative	135499405	C14H8Br2N2O	380.03	C1=CC=NC(=C1)/C(=C/C2=CC(=C(C(=C2)Br)O)Br)/C#N	IC50 = 105000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B7J1GF	7-((4-Methylpiperazin-1-yl)methyl)-3-(thiophen-3-yl)-1,4-dihydroindeno[1,2-c]pyrazole	Investigative	44414347	C20H22N4S	350.5	CN1CCN(CC1)CC2=CC3=C(CC4=C3NN=C4C5=CSC=C5)C=C2	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B7LH4E	6-Hydroxy-2-imino-2H-1-benzopyran-3-carboxamide	Investigative	10104347	C10H8N2O3	204.18	C1=CC2=C(C=C1O)C=C(C(=N)O2)C(=O)N	IC50 = 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B7N1WR	3-[(E)-2-(4-Chlorophenyl)ethenyl]-N-[(2S)-2,3-dihydroxypropyl]-4-methoxybenzamide	Investigative	57325479	C19H20ClNO4	361.8	COC1=C(C=C(C=C1)C(=O)NC[C@@H](CO)O)/C=C/C2=CC=C(C=C2)Cl	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B7XCA2	(2-Bromo-phenyl)-imidazo[1,2-a]quinoxalin-4-yl-amine	Investigative	12911686	C16H11BrN4	339.19	C1=CC=C2C(=C1)N=C(C3=NC=CN23)NC4=CC=CC=C4Br	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B7ZDB8	(R)-6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinoline	Investigative	46232443	C17H12Cl2FNO	336.2	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=C(C=C2)N=CC=C3	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B8DAK7	5-(6,7-Dihydroxynaphthalen-2-yl)-2-hydroxybenzoic acid	Investigative	380855	C17H12O5	296.27	C1=CC2=CC(=C(C=C2C=C1C3=CC(=C(C=C3)O)C(=O)O)O)O	IC50 = 150000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B8IJH7	3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrole-2,5-dione	Investigative	2404	C26H24N4O2	424.5	CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5CC(CCN5C6=CC=CC=C64)CN	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B8TB0F	(R)-3-(3,4-Dihydroxy-phenyl)-2-[(E)-3-(3,4-dihydroxy-phenyl)-acryloylamino]-propionic acid methyl ester	Investigative	11337764	C19H19NO7	373.4	COC(=O)[C@@H](CC1=CC(=C(C=C1)O)O)NC(=O)/C=C/C2=CC(=C(C=C2)O)O	IC50 = 121000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B9BKW5	N-(3,4,5-Trimethoxyphenyl)-7H-purin-6-amine;hydrochloride	Investigative	45265063	C14H16ClN5O3	337.76	COC1=CC(=CC(=C1OC)OC)NC2=NC=NC3=C2NC=N3.Cl	IC50 = 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B9OES1	1-(3-(8-(Pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea	Investigative	11755812	C26H20F3N7O	503.5	C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CN4C=CN=C4C(=N3)NCC5=CC=NC=C5	IC50 = 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	B9PWE5	[5-(1,2-Dimethyl-propylcarbamoyl)-4-methyl-thiazol-2-yl]-carbamic acid tert-butyl ester	Investigative	11186472	C15H25N3O3S	327.4	CC1=C(SC(=N1)NC(=O)OC(C)(C)C)C(=O)NC(C)C(C)C	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BB81WN	Chembl4171175	Investigative	142749658	C28H29N5O6	531.6	CC1=CC(=C(C=C1)OC2=NC(=NC=C2NC(=O)NC3=CC=C(C=C3)OC)NC4=CC(=CC(=C4)OC)OC)OC	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BBA86V	2-(4-(1H-Pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide	Investigative	16223008	C25H16F3N5O2	475.4	C1=CC(=C(N=C1)NC2=CC(=C(C=C2)OC3=C4C=CNC4=NC=C3)F)C(=O)NC5=C(C=C(C=C5)F)F	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BBU16M	6,7-Dimethoxy-N-(4-morpholin-4-ylphenyl)quinazolin-4-amine;hydrochloride	Investigative	18770815	C20H23ClN4O3	402.9	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)N4CCOCC4)OC.Cl	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BBYX32	N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-5-[2-[3-fluoro-4-(pyrrolidin-1-ylmethyl)phenyl]ethynyl]-6-methylpyrimidin-4-amine	Investigative	56835161	C31H27ClF2N4O	545	CC1=C(C(=NC=N1)NC2=CC(=C(C=C2)OCC3=CC(=CC=C3)F)Cl)C#CC4=CC(=C(C=C4)CN5CCCC5)F	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BC7DB4	N-(5-Carbamoyl-2-methylphenyl)-2-(isopropylamino)thiazole-5-carboxamide	Investigative	11381572	C15H18N4O2S	318.4	CC1=C(C=C(C=C1)C(=O)N)NC(=O)C2=CN=C(S2)NC(C)C	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BCE0X3	(R)-3-(3,4-Dihydroxy-phenyl)-2-{[(E)-3-(3,4-dihydroxy-phenyl)-acryloyl]-methyl-amino}-propionic acid methyl ester	Investigative	10126524	C20H21NO7	387.4	CN([C@H](CC1=CC(=C(C=C1)O)O)C(=O)OC)C(=O)/C=C/C2=CC(=C(C=C2)O)O	IC50 = 149000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BDCI37	2-Chloro-6,7-dimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin-4-amine;hydrochloride	Investigative	45262047	C19H21Cl2N3O5	442.3	COC1=CC(=CC(=C1OC)OC)NC2=NC(=NC3=CC(=C(C=C32)OC)OC)Cl.Cl	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BDV56G	Bisindolylmaleimide xi, HCl	Investigative	11605551	C28H29ClN4O2	489	CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=C5CC(CCN5C6=CC=CC=C64)CN(C)C.Cl	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BE75FL	3-(3,4-Dimethoxystyryl)Pyridine	Investigative	44307877	C15H15NO2	241.28	COC1=C(C=C(C=C1)/C=C/C2=CN=CC=C2)OC	IC50 = 178000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BEK59Y	N-(2,3-Dihydro-1H-inden-5-yl)-6,7-dimethoxyquinazolin-4-amine;hydrochloride	Investigative	18770787	C19H20ClN3O2	357.8	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC4=C(CCC4)C=C3)OC.Cl	IC50 = 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BF5M6P	2-(2-Methoxy-ethoxy)-N-{3-[5-(3-phenoxy-prop-1-ynyl)-thiophen-3-yl]-2,4-dihydro-indeno[1,2-c]pyrazol-5-yl}-acetamide	Investigative	44440256	C28H25N3O4S	499.6	COCCOCC(=O)NC1=CC=CC2=C1CC3=C2NN=C3C4=CSC(=C4)C#CCOC5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BF71IL	4',6-Diaminoflavone	Investigative	10037831	C15H12N2O2	252.27	C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=CC(=C3)N)N	IC50 = 103000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BFZ8M9	2-(2-(2-(6-Amino-9H-purin-9-yl)-N-(2-((R)-1-((S)-3-(4-benzoylphenyl)-2-(4-(5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamido)butanamido)propanoyl)piperidine-2-carboxamido)ethyl)acetamido)acetamido)acetic acid	Investigative	44579360	C49H61N13O10S	1024.2	C1CCN([C@H](C1)C(=O)NCCN(CC(=O)NCC(=O)O)C(=O)CN2C=NC3=C(N=CN=C32)N)C(=O)[C@H](CC4=CC=C(C=C4)C(=O)C5=CC=CC=C5)NC(=O)CCCNC(=O)CCCC[C@H]6[C@@H]7[C@H](CS6)NC(=O)N7	EC50 ~ 150000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BG0YC3	4'-Amino-7-hydroxyflavone	Investigative	14791392	C15H11NO3	253.25	C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C=C(C=C3)O)N	IC50 = 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BG54YN	2-(Isopropylamino)-N-(2-methyl-5-(methylcarbamoyl)phenyl)thiazole-5-carboxamide	Investigative	11256035	C16H20N4O2S	332.4	CC1=C(C=C(C=C1)C(=O)NC)NC(=O)C2=CN=C(S2)NC(C)C	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BGI60E	6-Chloro-N-(3,4,5-trimethoxyphenyl)quinazolin-4-amine;hydrochloride	Investigative	45261978	C17H17Cl2N3O3	382.2	COC1=CC(=CC(=C1OC)OC)NC2=NC=NC3=C2C=C(C=C3)Cl.Cl	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BGU07I	8-Hydroxy-2-imino-2H-chromene-3-carboxamide	Investigative	10397980	C10H8N2O3	204.18	C1=CC2=C(C(=C1)O)OC(=N)C(=C2)C(=O)N	IC50 = 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BH0OC1	4-(Isopentyloxy)-5-benzoyl-1H-pyrazolo[3,4-b]pyridine	Investigative	135402873	C18H19N3O2	309.4	CC(C)CCOC1=C(C=NC2=NNC=C12)C(=O)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BH6CK5	3-[[3-((3-{[3-(Bis-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-[2-(2,5-dioxo-3,4-diphenyl-2,5-dihydro-pyrrol-1-yl)-ethyl]-amino}-propyl)-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-(2-cyano-ethyl)-amino]-propionitrile	Investigative	11051416	C60H82N16O2	1059.4	C1=CC=C(C=C1)C2=C(C(=O)N(C2=O)CCN(CCCN(CCCN(CCC#N)CCC#N)CCCN(CCC#N)CCC#N)CCCN(CCCN(CCC#N)CCC#N)CCCN(CCC#N)CCC#N)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BHS12E	(R)-3-(3,4-Dihydroxy-phenyl)-2-[(E)-3-(3,4-dihydroxy-phenyl)-thioacryloylamino]-propionic acid methyl ester	Investigative	135546620	C19H19NO6S	389.4	COC(=O)[C@@H](CC1=CC(=C(C=C1)O)O)NC(=S)/C=C/C2=CC(=C(C=C2)O)O	IC50 = 162000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BJO45U	(S)-2-(Sec-butylamino)-N-(2-methyl-5-(methylcarbamoyl)phenyl)thiazole-5-carboxamide	Investigative	11268003	C17H22N4O2S	346.4	CC[C@H](C)NC1=NC=C(S1)C(=O)NC2=C(C=CC(=C2)C(=O)NC)C	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BJRN35	(3-Chlorophenyl)quinazolin-4-ylamine, chloride	Investigative	2789324	C14H11Cl2N3	292.2	C1=CC=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl.Cl	IC50 = 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BK7ZS0	Coc1=CC(O)=CC=C1C1=CC=C(C(=NN2)C=3NC4=CC=C(C=C4N=3)N(C)C)C2=C1	Investigative	136115596	C23H21N5O2	399.4	CN(C)C1=CC2=C(C=C1)N=C(N2)C3=NNC4=C3C=CC(=C4)C5=C(C=C(C=C5)O)OC	Ki = 87000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BKWE20	N2-(4-(4-Amino-1-(1-(tetrahydro-2H-pyran-4-yl)piperidin-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-2-methoxyphenyl)-1-methyl-1H-indole-2,5-dicarboxamide	Investigative	44406138	C33H37N9O4	623.7	CN1C2=C(C=C(C=C2)C(=O)N)C=C1C(=O)NC3=C(C=C(C=C3)C4=NN(C5=NC=NC(=C45)N)C6CCN(CC6)C7CCOCC7)OC	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BM51KZ	Caftaric acid	Investigative	6440397	C13H12O9	312.23	C1=CC(=C(C=C1/C=C/C(=O)O[C@H]([C@H](C(=O)O)O)C(=O)O)O)O	IC50 = 118000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BMHZ45	4',8-Diaminoflavone	Investigative	10264200	C15H12N2O2	252.27	C1=CC2=C(C(=C1)N)OC(=CC2=O)C3=CC=C(C=C3)N	IC50 = 123000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BN24XG	4-[(2,4-Dinitro-phenyl)-hydrazonomethyl]-benzene-1,2,3-triol	Investigative	136056094	C13H10N4O7	334.24	C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])N/N=C/C2=C(C(=C(C=C2)O)O)O	IC50 = 144000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BN3Y0E	3-[[5-Cyano-6-(cyclopentylamino)pyrimidin-4-yl]amino]-4-methyl-N-(1,2-oxazol-3-yl)benzamide	Investigative	11235063	C21H21N7O2	403.4	CC1=C(C=C(C=C1)C(=O)NC2=NOC=C2)NC3=C(C(=NC=N3)NC4CCCC4)C#N	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BOFD79	Pyrazolopyridazine 1a	Investigative	6263849	C17H13N5	287.32	C1=CC=C(C=C1)C2=C(N=NC3=NNC(=C23)N)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BPF61Y	4',6-Diamino-7-hydroxyflavone	Investigative	9970231	C15H12N2O3	268.27	C1=CC(=CC=C1C2=CC(=O)C3=CC(=C(C=C3O2)O)N)N	IC50 = 141000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BQ5E2O	4-(3,4-Dimethoxy-phenylsulfanyl)-6,7-dimethoxy-quinazoline	Investigative	44355456	C18H18N2O4S	358.4	COC1=C(C=C(C=C1)SC2=NC=NC3=CC(=C(C=C32)OC)OC)OC	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BQX9A6	N-Cyclopropyl-2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5-yl)methylamino)benzamide	Investigative	11632737	C19H17F2N5OS	401.4	C1CC1NC(=O)C2=CC(=C(C=C2F)F)NCC3=CN=C(S3)NC4=CC=CC=N4	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BRN8J1	N-[3-(2-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide	Investigative	24822704	C25H16F3N5O	459.4	C1=CC(=CC(=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C3=CC=NC4=CC(=NN34)C5=CC=NC=C5	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BRWP09	3',6-Diaminoflavone	Investigative	10264201	C15H12N2O2	252.27	C1=CC(=CC(=C1)N)C2=CC(=O)C3=C(O2)C=CC(=C3)N	IC50 = 200000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BSC1P3	(E)-2-Cyano-3-(2,5-dihydroxy-phenyl)-acrylamide	Investigative	5388678	C10H8N2O3	204.18	C1=CC(=C(C=C1O)/C=C(\\C#N)/C(=O)N)O	IC50 = 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BTF2Y1	4',6,8-Triaminoflavone	Investigative	10038606	C15H13N3O2	267.28	C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=CC(=C3)N)N)N	IC50 = 106000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BTU3S4	4'-Aminoflavone	Investigative	177048	C15H11NO2	237.25	C1=CC=C2C(=C1)C(=O)C=C(O2)C3=CC=C(C=C3)N	IC50 = 200000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BTV4O2	6,7,8-Trimethoxy-N-(3,4,5-trimethoxyphenyl)quinazolin-4-amine;hydrochloride	Investigative	24767186	C20H24ClN3O6	437.9	COC1=CC(=CC(=C1OC)OC)NC2=NC=NC3=C(C(=C(C=C32)OC)OC)OC.Cl	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BTYG57	AC-Dopa-eee	Investigative	73356106	C26H34N4O14	626.6	CC(=O)N[C@@H](CC1=CC(=C(C=C1)O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)O	IC50 = 120000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BUWN34	2-(4-p-Tolyl-1H-1,2,3-triazol-1-yl)cyclohexanone	Investigative	50941838	C15H17N3O	255.31	CC1=CC=C(C=C1)C2=CN(N=N2)C3CCCCC3=O	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BV6IP9	Chembl4168062	Investigative	142749651	C30H29F3N6O5	610.6	COC1=CC(=CC(=C1)NC(=O)NC2=CN=C(N=C2OC3=CC=C(C=C3)C(F)(F)F)NC4=CC=C(C=C4)N5CCOCC5)OC	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BVT70W	Chembl4175265	Investigative	145950233	C29H29FN6O5	560.6	COC1=CC(=CC(=C1)NC(=O)NC2=CN=C(N=C2OC3=CC=C(C=C3)F)NC4=CC=C(C=C4)N5CCOCC5)OC	IC50 = 71150 nM	Poor binder
T12499	LCK tyrosine protein kinase	BW08VY	3-[2-(3-Phenoxy-1-propynyl)-4-thienyl]-6-[(4-methyl-1-piperazinyl)methyl]-1,4-dihydroindeno[1,2-c]pyrazole	Investigative	16220354	C29H28N4OS	480.6	CN1CCN(CC1)CC2=CC3=C(C=C2)C4=C(C3)C(=NN4)C5=CSC(=C5)C#CCOC6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BW0B3Z	3,3',4-Trihydroxystilbene	Investigative	10466312	C14H12O3	228.24	C1=CC(=CC(=C1)O)/C=C/C2=CC(=C(C=C2)O)O	IC50 = 58000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BWM1Y9	3',8-Diamino-6-methoxyflavone	Investigative	10333957	C16H14N2O3	282.29	COC1=CC2=C(C(=C1)N)OC(=CC2=O)C3=CC(=CC=C3)N	IC50 = 56000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BWX3M9	4-Amino-3-(3-methoxy-4-(1-methyl-1H-indole-2-carboxamido)phenyl)thieno[3,2-c]pyridine-7-carboxylic acid	Investigative	18450830	C25H20N4O4S	472.5	CN1C2=CC=CC=C2C=C1C(=O)NC3=C(C=C(C=C3)C4=CSC5=C4C(=NC=C5C(=O)O)N)OC	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BYO4R3	4',8-Diamino-6-hydroxyflavone	Investigative	11777791	C15H12N2O3	268.27	C1=CC(=CC=C1C2=CC(=O)C3=C(O2)C(=CC(=C3)O)N)N	IC50 = 117000 nM	Poor binder
T12499	LCK tyrosine protein kinase	BZA10M	3-[[3-((3-{[3-(Bis-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-[2-(1,3-dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-ethyl]-amino}-propyl)-{3-[bis-(2-cyano-ethyl)-amino]-propyl}-amino)-propyl]-(2-cyano-ethyl)-amino]-propionitrile	Investigative	10909252	C56H78N16O2	1007.3	C1=CC2=C3C(=C1)C(=O)N(C(=O)C3=CC=C2)CCN(CCCN(CCCN(CCC#N)CCC#N)CCCN(CCC#N)CCC#N)CCCN(CCCN(CCC#N)CCC#N)CCCN(CCC#N)CCC#N	IC50 ~ 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	D01IZN	Y-c[D-Pen-(2')Nal-GSFC]KR-NH2	Investigative	44312289	C49H69N13O10S2	1064.3	CC(=O)N[C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](CSSC1(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N)CC2=CC=CC=C2)CO)CC3=CC4=CC=CC=C4C=C3	IC50 = 50000 nM	Poor binder
T12499	LCK tyrosine protein kinase	D05PTT	ROSMARINIC ACID	Investigative	5281792	C18H16O8	360.3	C1=CC(=C(C=C1C[C@H](C(=O)O)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O	IC50 = 55000 nM	Poor binder
T12499	LCK tyrosine protein kinase	D0FH3M	RPR-108514A	Investigative	18770833	C17H18ClN3O2	331.8	CN(C1=CC=CC=C1)C2=NC=NC3=CC(=C(C=C32)OC)OC.Cl	IC50 ~ 100000 nM	Poor binder
T12499	LCK tyrosine protein kinase	D0O0VZ	Piceatannol	Investigative	667639	C14H12O4	244.24	C1=CC(=C(C=C1/C=C/C2=CC(=CC(=C2)O)O)O)O	IC50 = 66000 nM	Poor binder