TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T12646 Valosin-containing protein p97 B6M3UZ 4-Bromo-2-[(1R,2S)-1,2-dimethyl-3-methylidenecyclopentyl]-5-methylphenol Investigative 470278 C15H19BrO 295.21 C[C@H]1C(=C)CC[C@@]1(C)C2=C(C=C(C(=C2)Br)C)O IC50 ~ 100000 nM Poor binder T12646 Valosin-containing protein p97 BR8FV5 (4S,6S)-7-Hydroxy-3,6,9-trimethyl-4-(2-methylprop-1-enyl)-5,6-dihydro-4H-phenalene-1,2-dione Investigative 397069 C20H22O3 310.4 C[C@H]1C[C@H](C2=C(C(=O)C(=O)C3=C2C1=C(C=C3C)O)C)C=C(C)C IC50 ~ 100000 nM Poor binder T12646 Valosin-containing protein p97 BY81XL Oxaspirol B Investigative 101907906 C17H20O5 304.34 CCC/C=C/C=C/[C@@H]1C=C[C@H]([C@@H](C12C(=O)C(=C)OC2=O)O)O IC50 = 180000 nM Poor binder