TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T12808	Protein kinase C alpha	D0AZ3C	Imatinib	Approved	5291	C29H31N7O	493.6	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	D0E6XR	Dasatinib	Approved	3062316	C22H26ClN7O2S	488	CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	D0J9ZR	Niclosamide	Approved	4477	C13H8Cl2N2O4	327.12	C1=CC(=C(C=C1[N+](=O)[O-])Cl)NC(=O)C2=C(C=CC(=C2)Cl)O	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	D0L4FS	Genistein	Phase 2	5280961	C15H10O5	270.24	C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	D06IPZ	MK-3281	Phase 1	49800096	C29H37N3O3	475.6	CN(C)CCN(C)[C@@H]1CN2C3=C(C=CC(=C3)C(=O)O)C(=C2C4=CC=CC=C4OC1)C5CCCCC5	IC50 = 59000 nM	Poor binder
T12808	Protein kinase C alpha	D0WS1V	L-751250	Preclinical	448991	C20H25ClN6O3	432.9	CC(C)[C@H](CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NC3=CC(=C(C=C3)C(=O)O)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B08AYZ	3-{[2-(3-Thienyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione	Investigative	44575127	C21H17N3O2S	375.4	C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC(=NC=C3)C4=CSC=C4	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B0AT4I	(1R)-2-[2,6-Dihydroxy-4-[(4R)-3-[(4-hydroxybenzoyl)amino]azepan-4-yl]oxycarbonylbenzoyl]cyclohexane-1-carboxylic acid	Investigative	44322741	C28H32N2O9	540.6	C1CCC([C@@H](C1)C(=O)O)C(=O)C2=C(C=C(C=C2O)C(=O)O[C@@H]3CCCNCC3NC(=O)C4=CC=C(C=C4)O)O	IC50 ~ 150000 nM	Poor binder
T12808	Protein kinase C alpha	B0NTO4	(6,7,8,9-Tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-m-tolyl-amine	Investigative	10660240	C17H18N4	278.35	CC1=CC(=CC=C1)NC2=NC=NC3=C2C4=C(N3)CCCC4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B0PV8T	2-[4-[[5-[3-(Methoxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	57523093	C26H21N3O4S	471.5	COCC1COC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B0SKF5	4-N-(3-Chlorophenyl)-3-N-[(4-methoxyphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine	Investigative	5327838	C19H17ClN6O	380.8	COC1=CC=C(C=C1)CNC2=NNC3=C2C(=NC=N3)NC4=CC(=CC=C4)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B0UJ3V	(3-Bromo-phenyl)-(6,7,8,9-tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-amine	Investigative	10569366	C16H15BrN4	343.22	C1CCC2=C(C1)C3=C(N2)N=CN=C3NC4=CC(=CC=C4)Br	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B0WLH8	N-(7-Methoxyquinolin-6-yl)thieno[3,2-d]pyrimidine-7-carboxamide	Investigative	58056356	C17H12N4O2S	336.4	COC1=C(C=C2C=CC=NC2=C1)NC(=O)C3=CSC4=CN=CN=C43	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B0WV4G	p38 MAP Kinase Inhibitor IX	Investigative	16730109	C22H17N7O2	411.4	CC1=C(C=C(C=C1)C(=O)NC2=NOC=C2)NC3=C4C=NN(C4=NC=N3)C5=CC=CC=C5	IC50 = 188000 nM	Poor binder
T12808	Protein kinase C alpha	B13BDT	3-Hydroxy-2-[4-[2-[(4-hydroxybenzoyl)amino]cyclopentyl]oxycarbonyl-2,6-dimethylbenzoyl]benzoic acid	Investigative	44322720	C29H27NO8	517.5	CC1=CC(=CC(=C1C(=O)C2=C(C=CC=C2O)C(=O)O)C)C(=O)OC3CCCC3NC(=O)C4=CC=C(C=C4)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B15DSU	9-(Azetidin-3-ylamino)-1-cyclopropyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one	Investigative	118721562	C16H19N5O2	313.35	C1CC1C2C(=O)NN=C3N2C4=C(C=CC(=C4)NC5CNC5)OC3	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B1CM9O	6-Hydroxy-12,13-dihydro-6H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione	Investigative	5480818	C20H11N3O3	341.3	C1=CC=C2C(=C1)C3=C4C(=C5C6=CC=CC=C6NC5=C3N2)C(=O)N(C4=O)O	IC50 = 79200 nM	Poor binder
T12808	Protein kinase C alpha	B1LGZ6	3,13-Diazahexacyclo[14.8.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tetracosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20,23-decaene-12,14-dione	Investigative	9797847	C22H12N2O2	336.3	C1=CC=C2C(=C1)C=CC3=C2C4=C(C5=C3NC6=CC=CC=C65)C(=O)NC4=O	IC50 = 52750 nM	Poor binder
T12808	Protein kinase C alpha	B1LV0O	2-(1,3-Benzodioxol-5-yl)-5-[[4-(4-methoxyphenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71578445	C23H18N2O4S	418.5	COC1=CC=C(C=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC5=C(C=C4)OCO5	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B1M4HQ	[3,4,5-Triacetyloxy-6-(13-methyl-12,14-dioxo-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4,6,8,10,15,17,19,21-nonaen-3-yl)oxan-2-yl]methyl acetate	Investigative	44343595	C35H31N3O11	669.6	CC(=O)OCC1C(C(C(C(O1)N2C3=CC=CC=C3C4=C5C(=C6C7=CC=CC=C7NC6=C42)C(=O)N(C5=O)C)OC(=O)C)OC(=O)C)OC(=O)C	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B1XKE7	CID 71578744	Investigative	71578744	C17H13N5O2S	351.4	CC(=O)NC1=NC=CC(=C1)C2=NN=C(O2)SCC3=CC(=CC=C3)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B2N0EW	N-[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]acetamide	Investigative	44273654	C28H24N4O10	576.5	CC(=O)NN1C(=O)C2=C3C4=C(C(=CC=C4)O)NC3=C5C(=C2C1=O)C6=C(N5C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 = 130000 nM	Poor binder
T12808	Protein kinase C alpha	B2TDR1	2-(1,3-Benzodioxol-5-yl)-5-[[4-(3,5-difluorophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71578446	C22H14F2N2O3S	424.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC(=CC(=C5)F)F	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B39ESB	Phenyl-(6,7,8,9-tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-amine	Investigative	13492281	C16H16N4	264.32	C1CCC2=C(C1)C3=C(N2)N=CN=C3NC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B3T9QN	Methyl 4-(6-(4-(methoxycarbonylamino)phenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44219749	C24H29N7O5	495.5	COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)C(=O)OC)C(=N2)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B3V9PA	2-[[4-(4-Methoxyphenyl)phenyl]methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole	Investigative	71212403	C21H17N3O2S	375.4	COC1=CC=C(C=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC=NC=C4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B46ABW	5,21-Dihydroxy-13-(methylamino)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	44273526	C27H24N4O9	548.5	CNN1C(=O)C2=C3C4=C(C(=CC=C4)O)NC3=C5C(=C2C1=O)C6=C(N5C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 = 55000 nM	Poor binder
T12808	Protein kinase C alpha	B46VEH	(5R,6S)-9-Dodecyl-6-hydroxymethyl-1,7-dioxa-spiro[4.4]nonane-2,8-dione	Investigative	44276150	C20H34O5	354.5	CCCCCCCCCCCCC1C(=O)O[C@H]([C@@]12CCC(=O)O2)CO	Ki = 75300 nM	Poor binder
T12808	Protein kinase C alpha	B4BQE5	Heptanoic acid (2S,3R)-2-hydroxymethyl-5-oxo-tetrahydro-furan-3-yl ester	Investigative	44276187	C12H20O5	244.28	CCCCCCC(=O)O[C@@H]1CC(=O)O[C@H]1CO	Ki = 187000 nM	Poor binder
T12808	Protein kinase C alpha	B4F1NE	2-[2,6-Dihydroxy-4-[[(3R,4S)-3-[(4-hydroxybenzoyl)amino]azepan-4-yl]-methylcarbamoyl]benzoyl]-3-hydroxybenzoic acid	Investigative	71718528	C29H29N3O9	563.6	CN([C@H]1CCCNC[C@H]1NC(=O)C2=CC=C(C=C2)O)C(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C=CC=C4O)C(=O)O)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B4FHT8	2-[[4-(3,5-Difluorophenyl)phenyl]methylsulfanyl]-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazole	Investigative	71212517	C23H16F2N2O3S	438.4	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC(=CC(=C5)F)F	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B4G2QZ	Methyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44605035	C22H27N7O3	437.5	COC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)N)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B4HU5D	Cyclapolin 9	Investigative	2779952	C9H4F3N3O4S	307.21	C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B4LCD2	1,1'-Hexamethylenebis(4-amino-2-methylquinolinium)	Investigative	130351	C26H32N4+2	400.6	CC1=[N+](C2=CC=CC=C2C(=C1)N)CCCCCC[N+]3=C(C=C(C4=CC=CC=C43)N)C	IC50 = 54000 nM	Poor binder
T12808	Protein kinase C alpha	B50KDA	4-Amino-1-decyl-2-methylquinolin-1-ium iodide	Investigative	10387733	C20H31IN2	426.4	CCCCCCCCCC[N+]1=C(C=C(C2=CC=CC=C21)N)C.[I-]	IC50 = 117000 nM	Poor binder
T12808	Protein kinase C alpha	B53ECV	N-[4-Methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide	Investigative	9864718	C23H19N5O	381.4	CC1=C(C=C(C=C1)NC(=O)C2=CC=CC=C2)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 = 72000 nM	Poor binder
T12808	Protein kinase C alpha	B57AIU	5H-Indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione, 6-amino-1,11-dichloro-12,13-dihydro-	Investigative	5480821	C20H10Cl2N4O2	409.2	C1=CC2=C(C(=C1)Cl)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)N)C6=C(N4)C(=CC=C6)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B5AST9	N-[4-[5-[[4-(2-Cyanophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazol-2-yl]pyridin-2-yl]acetamide	Investigative	71578745	C23H17N5O2S	427.5	CC(=O)NC1=NC=CC(=C1)C2=NN=C(O2)SCC3=CC=C(C=C3)C4=CC=CC=C4C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B5O9PW	2-Amino-9-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyperhydropyran-2-yl]-7,10-dichloroindolo[2,3-a]3-pyrrolino[3,4-c]carbazole-1,3-dione	Investigative	465908	C27H22Cl2N4O7	585.4	COC1C(OC(C(C1O)O)N2C3=C(C=CC=C3Cl)C4=C5C(=C6C7=C(C(=CC=C7)Cl)NC6=C42)C(=O)N(C5=O)N)CO	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B5S3GE	N-Benzoyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Investigative	44273619	C30H23N5O2	485.5	CC1=C(C=C(C=C1)N(C(=O)C2=CC=CC=C2)C(=O)C3=CC=CC=C3)NC4=NC=CC(=N4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B5YNV2	6,6-Dimethyl-8-(1-(oxetan-3-yl)piperidin-4-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile	Investigative	53357328	C27H27N3O2	425.5	CC1(C2=C(C=CC(=C2)C3CCN(CC3)C4COC4)C(=O)C5=C1NC6=C5C=CC(=C6)C#N)C	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B60CAW	(R)-3-(6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)acrylamide	Investigative	46232555	C20H15Cl2FN2O2	405.2	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=CC(=CN=C3C=C2)/C=C/C(=O)N	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B64DXM	13-(Dimethylamino)-5,21-dihydroxy-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	44273527	C28H26N4O9	562.5	CN(C)N1C(=O)C2=C3C4=C(C(=CC=C4)O)NC3=C5C(=C2C1=O)C6=C(N5C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 = 59000 nM	Poor binder
T12808	Protein kinase C alpha	B68WNO	6-(Formylamino)-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione	Investigative	5480816	C21H12N4O3	368.3	C1=CC=C2C(=C1)C3=C4C(=C5C6=CC=CC=C6NC5=C3N2)C(=O)N(C4=O)NC=O	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B6I1PT	N-[4-Methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-acetamide	Investigative	44273620	C18H17N5O	319.4	CC1=C(C=C(C=C1)NC(=O)C)NC2=NC=CC(=N2)C3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B6J8GD	3-[4-[(5-Pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]phenyl]benzonitrile	Investigative	71212514	C21H14N4OS	370.4	C1=CC(=CC(=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC=NC=C4)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B6PZ0U	N-[4-Methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]naphthalene-2-carboxamide	Investigative	10181160	C27H21N5O	431.5	CC1=C(C=C(C=C1)NC(=O)C2=CC3=CC=CC=C3C=C2)NC4=NC=CC(=N4)C5=CN=CC=C5	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B79PYV	(5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-(3-fluoro-phenyl)-amine	Investigative	10729749	C14H13FN4	256.279	CC1=C(NC2=C1C(=NC=N2)NC3=CC(=CC=C3)F)C	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B79YJF	2-[(4-Phenylphenyl)methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole	Investigative	24370907	C20H15N3OS	345.4	C1=CC=C(C=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC=NC=C4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B7FT6G	Rebeccamycin	Investigative	73110	C27H21Cl2N3O7	570.4	CO[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O)N2C3=C(C=CC=C3Cl)C4=C5C(=C6C7=C(C(=CC=C7)Cl)NC6=C42)C(=O)NC5=O)CO	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B7OY1C	2-[4-[(5-Pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]phenyl]benzonitrile	Investigative	30291292	C21H14N4OS	370.4	C1=CC=C(C(=C1)C#N)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC=NC=C4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B7X8DU	N-[4-Chloro-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Investigative	44273476	C22H16ClN5O	401.8	C1=CC=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B7ZDB8	(R)-6-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinoline	Investigative	46232443	C17H12Cl2FNO	336.2	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=C(C=C2)N=CC=C3	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B8R9BM	5-[6-(5-Difluoromethyl-[1,3,4]oxadiazol-2-yl)-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino]-2,4-difluoro-N-methoxy-benzamide	Investigative	10073832	C20H17F4N7O3	479.4	CC(C)C1=C2C(=NC=NN2C=C1C3=NN=C(O3)C(F)F)NC4=C(C=C(C(=C4)C(=O)NOC)F)F	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B8XG9W	3-{[(1R)-1-Phenylethyl]amino}-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione	Investigative	15295578	C17H15N3O2	293.32	C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC=NC=C3	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B8YTQ3	CID 49806721	Investigative	49806721	C28H30N4O2	454.6	CCC1=CC2=C(C=C1N3CCN(CC3)C4COC4)C(C5=C(C2=O)C6=C(N5)C=C(C=C6)C#N)(C)C	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B90MKA	(+)-(1R,3R)-1-(3-Hydroxy-cyclopentyl)-3-(4-methoxy-phenyl)-7-phenylamino-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one	Investigative	9910609	C24H25N5O3	431.5	COC1=CC=C(C=C1)N2CC3=CN=C(N=C3N(C2=O)[C@@H]4CC[C@H](C4)O)NC5=CC=CC=C5	IC50 ~ 125000 nM	Poor binder
T12808	Protein kinase C alpha	B92XMZ	4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (S)-1-(4-hydroxy-benzoylamino)-indan-2-yl ester	Investigative	44386931	C31H23NO10	569.5	C1C([C@H](C2=CC=CC=C21)NC(=O)C3=CC=C(C=C3)O)OC(=O)C4=CC(=C(C(=C4)O)C(=O)C5=C(C=CC=C5O)C(=O)O)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B93PBH	(1S)-2-[2,6-Dihydroxy-4-[(4R)-3-[(4-hydroxybenzoyl)amino]azepan-4-yl]oxycarbonylbenzoyl]cyclohexane-1-carboxylic acid	Investigative	44322686	C28H32N2O9	540.6	C1CCC([C@H](C1)C(=O)O)C(=O)C2=C(C=C(C=C2O)C(=O)O[C@@H]3CCCNCC3NC(=O)C4=CC=C(C=C4)O)O	IC50 ~ 150000 nM	Poor binder
T12808	Protein kinase C alpha	B97DIH	4-N-(3-Chlorophenyl)-3-N-[(3-methoxyphenyl)methyl]-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine	Investigative	5327837	C19H17ClN6O	380.8	COC1=CC=CC(=C1)CNC2=NNC3=C2C(=NC=N3)NC4=CC(=CC=C4)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B9HKQ6	N-[4-(5-Benzylsulfanyl-1,3,4-oxadiazol-2-yl)pyridin-2-yl]acetamide	Investigative	71578658	C16H14N4O2S	326.4	CC(=O)NC1=NC=CC(=C1)C2=NN=C(O2)SCC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B9LSF5	2,4-Difluoro-5-[5-isopropyl-6-(5-methyl-[1,3,4]oxadiazol-2-yl)-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino]-N-methoxy-benzamide	Investigative	10478569	C20H19F2N7O3	443.4	CC1=NN=C(O1)C2=CN3C(=C2C(C)C)C(=NC=N3)NC4=C(C=C(C(=C4)C(=O)NOC)F)F	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	B9MO5H	N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine	Investigative	9965429	C16H15N5	277.32	CC1=C(C=C(C=C1)N)NC2=NC=CC(=N2)C3=CN=CC=C3	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	B9OES1	1-(3-(8-(Pyridin-4-ylmethylamino)imidazo[1,2-a]pyrazin-6-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea	Investigative	11755812	C26H20F3N7O	503.5	C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(F)(F)F)C3=CN4C=CN=C4C(=N3)NCC5=CC=NC=C5	IC50 = 50000 nM	Poor binder
T12808	Protein kinase C alpha	B9U8LP	2-N-(2-Aminoethyl)-9-ethyl-6-N-[3-(trifluoromethyl)phenyl]purine-2,6-diamine;hydrochloride	Investigative	45263073	C16H19ClF3N7	401.8	CCN1C=NC2=C(N=C(N=C21)NCCN)NC3=CC=CC(=C3)C(F)(F)F.Cl	IC50 = 50000 nM	Poor binder
T12808	Protein kinase C alpha	BA62QX	4-(4-Methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrolidin-1-yl)prop-1-enyl)thieno[2,3-b]pyridine-5-carbonitrile	Investigative	24766030	C24H21N5OS	427.5	CC1=C(C=CC2=C1C=CN2)NC3=C4C=C(SC4=NC=C3C#N)/C=C/C(=O)N5CCCC5	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BA6CV3	[2-[(4-Hydroxybenzoyl)amino]cyclopentyl] 3,5-dihydroxy-4-(8-hydroxy-4-oxo-3H-phthalazin-1-yl)benzoate	Investigative	136026545	C27H23N3O8	517.5	C1CC(C(C1)OC(=O)C2=CC(=C(C(=C2)O)C3=NNC(=O)C4=C3C(=CC=C4)O)O)NC(=O)C5=CC=C(C=C5)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BB31EG	Modified Benzophenone Carboxylic Acid, Balanol Analog 37	Investigative	5327996	C28H23F3N2O9	588.5	C1C[C@H]([C@@H](C1)OC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)NC(=O)C(F)(F)F)O)NC(=O)C4=CC=C(C=C4)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BBA86V	2-(4-(1H-Pyrrolo[2,3-b]pyridin-4-yloxy)-3-fluorophenylamino)-N-(2,4-difluorophenyl)nicotinamide	Investigative	16223008	C25H16F3N5O2	475.4	C1=CC(=C(N=C1)NC2=CC(=C(C=C2)OC3=C4C=CNC4=NC=C3)F)C(=O)NC5=C(C=C(C=C5)F)F	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BBS72W	1-[(E)-Dec-5-enyl]-2-methylquinolin-1-ium-4-amine	Investigative	71452743	C20H29N2+	297.5	CCCC/C=C/CCCC[N+]1=C(C=C(C2=CC=CC=C21)N)C	IC50 = 137000 nM	Poor binder
T12808	Protein kinase C alpha	BCRO12	2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[[4-(2-nitrophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71578307	C23H17N3O5S	447.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BD87GN	12-(4-O-Methyl-beta-D-glucopyranosyl)-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione	Investigative	10323743	C27H23N3O7	501.5	CO[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O)N2C3=CC=CC=C3C4=C5C(=C6C7=CC=CC=C7NC6=C42)C(=O)NC5=O)CO	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BD9GE4	2-[4-[[5-(1,3-Benzodioxol-5-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]-5-methoxybenzonitrile	Investigative	71212317	C24H17N3O4S	443.5	COC1=CC(=C(C=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC5=C(C=C4)OCO5)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BE3V4Z	[(4R)-3-[(4-Hydroxybenzoyl)amino]azepan-4-yl] 3,5-dihydroxy-4-(1-hydroxynaphthalene-2-carbonyl)benzoate	Investigative	44322982	C31H28N2O8	556.6	C1C[C@H](C(CNC1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=C(C5=CC=CC=C5C=C4)O)O	IC50 ~ 150000 nM	Poor binder
T12808	Protein kinase C alpha	BE5H6O	Formamide, (1,11-dichloro-5,7,12,13-tetrahydro-5,7-dioxo-6H-indolo(2,3-a)pyrrolo(3,4-c)carbazol-6-yl)-	Investigative	5480822	C21H10Cl2N4O3	437.2	C1=CC2=C(C(=C1)Cl)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NC=O)C6=C(N4)C(=CC=C6)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BE63UG	4,N*1*-Dimethyl-N*3*-(4-pyridin-3-yl-pyrimidin-2-yl)-benzene-1,3-diamine	Investigative	44273595	C17H17N5	291.35	CC1=C(C=C(C=C1)NC)NC2=NC=CC(=N2)C3=CN=CC=C3	IC50 = 71000 nM	Poor binder
T12808	Protein kinase C alpha	BE6VT1	Ferruginoside C	Investigative	10581173	C37H50O19	798.8	C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OCCC3=CC(=C(C=C3)OC)O)O)O[C@H]4[C@@H]([C@@H]([C@H]([C@@H](O4)C)O)O)O)OC(=O)/C=C/C5=CC(=C(C=C5)O)OC)O)O)O	IC50 = 125000 nM	Poor binder
T12808	Protein kinase C alpha	BE8T9F	3-Hydroxy-2-[4-[4-[(4-hydroxybenzoyl)amino]pyrrolidin-3-yl]oxycarbonylphenyl]benzoic acid	Investigative	44323003	C25H22N2O7	462.4	C1C(C(CN1)OC(=O)C2=CC=C(C=C2)C3=C(C=CC=C3O)C(=O)O)NC(=O)C4=CC=C(C=C4)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BEI4R1	[2-[(4-Hydroxybenzoyl)amino]cyclopentyl] 3,5-dihydroxy-4-[2-hydroxy-6-[(2,2,2-trifluoroacetyl)amino]benzoyl]benzoate	Investigative	44322815	C28H23F3N2O9	588.5	C1CC(C(C1)OC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)NC(=O)C(F)(F)F)O)NC(=O)C4=CC=C(C=C4)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BEP25N	2-[[4-(2-Nitrophenyl)phenyl]methylsulfanyl]-5-pyridin-4-yl-1,3,4-oxadiazole	Investigative	71578447	C20H14N4O3S	390.4	C1=CC=C(C(=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC=NC=C4)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BEXC97	9-[3,4-Dihydroxy-6-(hydroxymethyl)-5-methoxyperhydropyran-2-yl]-7,10-dichloro-2-hydroxyindolo[2,3-a]3-pyrrolino[3,4-c]carbazole-1,3-dione	Investigative	465909	C27H21Cl2N3O8	586.4	COC1C(OC(C(C1O)O)N2C3=C(C=CC=C3Cl)C4=C5C(=C6C7=C(C(=CC=C7)Cl)NC6=C42)C(=O)N(C5=O)O)CO	IC50 = 68000 nM	Poor binder
T12808	Protein kinase C alpha	BF1VW2	pi-103 (Hydrochloride)	Investigative	16739368	C19H17ClN4O3	384.8	C1COCCN1C2=NC(=NC3=C2OC4=C3C=CC=N4)C5=CC(=CC=C5)O.Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BF51YV	3,5-Dihydro[1,2,4]triazino[3,4-C][1,4]benzoxazin-2(1h)-One	Investigative	3071991	C10H9N3O2	203.2	C1C(=O)NN=C2N1C3=CC=CC=C3OC2	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BF72JY	Dichloroarcyriaflavin A	Investigative	5480817	C20H9Cl2N3O2	394.2	C1=CC2=C(C(=C1)Cl)NC3=C4C(=C5C(=C23)C(=O)NC5=O)C6=C(N4)C(=CC=C6)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BFL75U	[3-Hydroxy-2-(4-phenylmethoxyphenyl)propyl] 2-phenylacetate	Investigative	122194654	C24H24O4	376.4	C1=CC=C(C=C1)CC(=O)OCC(CO)C2=CC=C(C=C2)OCC3=CC=CC=C3	IC50 = 73900 nM	Poor binder
T12808	Protein kinase C alpha	BG1T9K	4-[4-[(5-Pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]phenyl]benzonitrile	Investigative	71212434	C21H14N4OS	370.4	C1=CC(=CC=C1CSC2=NN=C(O2)C3=CC=NC=C3)C4=CC=C(C=C4)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BG3S1X	2-[[5,21-Dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]amino]acetic acid	Investigative	44273617	C28H24N4O11	592.5	C1=CC2=C(C(=C1)O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NCC(=O)O)C6=C(N4C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 = 110000 nM	Poor binder
T12808	Protein kinase C alpha	BG40KU	[4-(2,4-Difluoro-5-methoxycarbamoyl-phenylamino)-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl]-carbamic acid tetrahydro-furan-2-ylmethyl ester	Investigative	11477626	C23H26F2N6O5	504.5	CC(C)C1=C2C(=NC=NN2C=C1NC(=O)OCC3CCCO3)NC4=C(C=C(C(=C4)C(=O)NOC)F)F	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BG4PM6	1,11-Dichloro-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one	Investigative	465959	C20H11Cl2N3O	380.2	C1C2=C3C4=C(C(=CC=C4)Cl)NC3=C5C(=C2C(=O)N1)C6=C(N5)C(=CC=C6)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BG4R6T	N-(3-Chlorophenyl)-9H-pyrimido[4,5-b]indol-4-amine	Investigative	9882602	C16H11ClN4	294.74	C1=CC=C2C(=C1)C3=C(N2)N=CN=C3NC4=CC(=CC=C4)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BG7Y0L	Xanthohumol	Investigative	639665	C21H22O5	354.4	CC(=CCC1=C(C(=C(C=C1O)OC)C(=O)/C=C/C2=CC=C(C=C2)O)O)C	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BGRS23	6-(2-Hydroxyethyl)-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7(6H)-dione	Investigative	5480819	C22H15N3O3	369.4	C1=CC=C2C(=C1)C3=C4C(=C5C6=CC=CC=C6NC5=C3N2)C(=O)N(C4=O)CCO	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BHTK41	2-[4-[[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]-5-methoxybenzonitrile	Investigative	71212446	C25H19N3O4S	457.5	COC1=CC(=C(C=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC5=C(C=C4)OCCO5)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BI0J6M	4-Chloro-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide	Investigative	9953676	C23H18ClN5O	415.9	CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)Cl)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BI1E4L	1-(Methoxycarbonylmethyl)-5-hydroxy-7-methoxy-3-(3-chlorophenyl)quinoline-4(1H)-one	Investigative	10499619	C19H16ClNO5	373.8	COC1=CC2=C(C(=C1)O)C(=O)C(=CN2CC(=O)OC)C3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BIKV80	3-[[2-(2-Fluorophenyl)pyridin-4-yl]amino]-4-[[(1R)-1-phenylethyl]amino]cyclobut-3-ene-1,2-dione	Investigative	44575073	C23H18FN3O2	387.4	C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC(=NC=C3)C4=CC=CC=C4F	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BIO5X9	2-(1,3-Benzodioxol-5-yl)-5-[[4-(3-nitrophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71578375	C22H15N3O5S	433.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC(=CC=C5)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BJ4VC0	4-(3-Chlorophenylamino)-5,6-dimethyl-7H-pyrrolo(2,3-d)pyrimidine	Investigative	9816954	C14H13ClN4	272.73	CC1=C(NC2=C1C(=NC=N2)NC3=CC(=CC=C3)Cl)C	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BJ69QM	2-(2H-1,3-Benzodioxol-5-yl)-5-[({[1,1'-biphenyl]-4-yl}methyl)sulfanyl]-1,3,4-oxadiazole	Investigative	7458031	C22H16N2O3S	388.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BJK14U	4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 31	Investigative	5327847	C17H11Cl2N5O	372.2	C1=CC(=CC(=C1)Cl)NC2=C3C(=NN2)N=CN=C3OC4=CC(=CC=C4)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BJM01F	4-[4-[[5-(1,3-Benzodioxol-5-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	57522818	C23H15N3O3S	413.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=C(C=C5)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BJUX64	3-(3-Chloro-phenyl)-5-hydroxy-7-methoxy-chromen-4-one	Investigative	10590515	C16H11ClO4	302.71	COC1=CC(=C2C(=C1)OC=C(C2=O)C3=CC(=CC=C3)Cl)O	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BK1FQ8	2-[[2,6-Dihydroxy-4-[4-[(4-hydroxybenzoyl)amino]pyrrolidin-3-yl]oxycarbonylbenzoyl]amino]benzoic acid	Investigative	44322684	C26H23N3O9	521.5	C1C(C(CN1)OC(=O)C2=CC(=C(C(=C2)O)C(=O)NC3=CC=CC=C3C(=O)O)O)NC(=O)C4=CC=C(C=C4)O	IC50 ~ 150000 nM	Poor binder
T12808	Protein kinase C alpha	BK1V8Q	3-{[2-(2-Furyl)pyridin-4-yl]amino}-4-{[(1R)-1-phenylethyl]amino}cyclobut-3-ene-1,2-dione	Investigative	44575126	C21H17N3O3	359.4	C[C@H](C1=CC=CC=C1)NC2=C(C(=O)C2=O)NC3=CC(=NC=C3)C4=CC=CO4	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BK2GQ1	N-Benzyl-N-methyl-4-(phenylsulfamoyl)benzamide	Investigative	27666048	C21H20N2O3S	380.5	CN(CC1=CC=CC=C1)C(=O)C2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BK59PQ	2-(1,3-Benzodioxol-5-yl)-5-[[4-(2-nitrophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71578373	C22H15N3O5S	433.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BKG4U0	5,7-Dihydroxy-3-(3-chlorophenyl)quinoline-4(1H)-one	Investigative	10803234	C15H10ClNO3	287.7	C1=CC(=CC(=C1)Cl)C2=CNC3=C(C2=O)C(=CC(=C3)O)O	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BKH38T	(2S,5S)-5-Hydroxymethyl-2-isopropyl-1-methyl-1,2,4,5-tetrahydro-benzo[e][1,4]diazepin-3-one	Investigative	12067104	C14H20N2O2	248.32	CC(C)[C@H]1C(=O)N[C@@H](C2=CC=CC=C2N1C)CO	Ki = 127000 nM	Poor binder
T12808	Protein kinase C alpha	BKJG61	1,11-Dichloro-7-hydroxy-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one	Investigative	465961	C20H11Cl2N3O2	396.2	C1=CC2=C(C(=C1)Cl)NC3=C4C(=C5C(=C23)C(NC5=O)O)C6=C(N4)C(=CC=C6)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BKL1O8	N-(3-Bromophenyl)-5,6-dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	10615400	C14H13BrN4	317.18	CC1=C(NC2=C1C(=NC=N2)NC3=CC(=CC=C3)Br)C	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BKP2S3	N-[5,21-Dichloro-3-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-12,14-dioxo-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]formamide	Investigative	465910	C28H22Cl2N4O8	613.4	COC1C(OC(C(C1O)O)N2C3=C(C=CC=C3Cl)C4=C5C(=C6C7=C(C(=CC=C7)Cl)NC6=C42)C(=O)N(C5=O)NC=O)CO	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BM1P3R	Acyclic Balanol Analog 13b	Investigative	5327955	C29H23NO11S	593.6	C1=CC=C(C=C1)S(=O)(=O)NC(COC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3O)C(=O)O)O)C4=CC=C(C=C4)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BMED31	2-[4-[[5-[(3R)-3-(Methoxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	57523094	C26H21N3O4S	471.5	COC[C@@H]1COC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BMP0C7	Tert-Butyl 4-(6-(4-aminophenyl)-4-morpholino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidine-1-carboxylate	Investigative	44605037	C25H33N7O3	479.6	CC(C)(C)OC(=O)N1CCC(CC1)N2C3=C(C=N2)C(=NC(=N3)C4=CC=C(C=C4)N)N5CCOCC5	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BMT5N8	13-Methyl-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4,6,8,10,15,17,19,21-nonaene-12,14-dione	Investigative	392223	C27H23N3O7	501.5	CN1C(=O)C2=C3C4=CC=CC=C4NC3=C5C(=C2C1=O)C6=CC=CC=C6N5C7C(C(C(C(O7)CO)O)O)O	IC50 = 59000 nM	Poor binder
T12808	Protein kinase C alpha	BMU8S1	2-[4-[[5-(1,3-Benzodioxol-5-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]-5-fluorobenzonitrile	Investigative	57522817	C23H14FN3O3S	431.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=C(C=C(C=C5)F)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BN17KD	4-(2-Carboxy-6-hydroxy-benzoyl)-3,5-dihydroxy-benzoic acid (1R,2R)-1-(4-hydroxy-benzoylamino)-indan-2-yl ester	Investigative	10460643	C31H23NO10	569.5	C1[C@H]([C@@H](C2=CC=CC=C21)NC(=O)C3=CC=C(C=C3)O)OC(=O)C4=CC(=C(C(=C4)O)C(=O)C5=C(C=CC=C5O)C(=O)O)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BN24SQ	2-Benzothiazolecarboxamide, 7-nitro-5-[(trifluoromethyl)thio]-, 3-oxide	Investigative	9548013	C9H4F3N3O4S2	339.3	C1=C(C=C(C2=C1[N+](=C(S2)C(=O)N)[O-])[N+](=O)[O-])SC(F)(F)F	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BN34TA	6-(5-Methyl-1,3,4-oxadiazol-2-yl)-5-propan-2-yl-N-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine	Investigative	44449577	C19H18N8O	374.4	CC1=NN=C(O1)C2=CN3C(=C2C(C)C)C(=NC=N3)NC4=CN=C5C(=C4)C=CN5	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BNEM28	[(4R)-3-[(4-Hydroxybenzoyl)amino]azepan-4-yl] 3,5-dihydroxy-4-(2-hydroxybenzoyl)benzoate	Investigative	44322520	C27H26N2O8	506.5	C1C[C@H](C(CNC1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C(C(=C3)O)C(=O)C4=CC=CC=C4O)O	IC50 = 97000 nM	Poor binder
T12808	Protein kinase C alpha	BO02QN	2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[[4-(4-methoxyphenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71212395	C24H20N2O4S	432.5	COC1=CC=C(C=C1)C2=CC=C(C=C2)CSC3=NN=C(O3)C4=CC5=C(C=C4)OCCO5	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BO0JH1	2-[4-[[5-[(3S)-3-(Methoxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	57523095	C26H21N3O4S	471.5	COC[C@H]1COC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BOBD84	8-Hydroxy-6-[(4R)-3-[(4-hydroxybenzoyl)amino]azepan-4-yl]oxycarbonyl-9-oxoxanthene-1-carboxylic acid	Investigative	44322714	C28H24N2O9	532.5	C1C[C@H](C(CNC1)NC(=O)C2=CC=C(C=C2)O)OC(=O)C3=CC(=C4C(=C3)OC5=CC=CC(=C5C4=O)C(=O)O)O	IC50 ~ 150000 nM	Poor binder
T12808	Protein kinase C alpha	BP48LA	2-(2-Amino-ethyl-amino)-6-(3-cyano-phenyl-amino)-9-ethyl-9H-purine hydrochloride	Investigative	21988184	C16H19ClN8	358.8	CCN1C=NC2=C(N=C(N=C21)NCCN)NC3=CC=CC(=C3)C#N.Cl	IC50 = 78000 nM	Poor binder
T12808	Protein kinase C alpha	BPD3K7	6-Methyl-12-(4-O-methyl--D-glucopyranosyl)-12,13-dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5,7-dione	Investigative	10481621	C28H25N3O7	515.5	CN1C(=O)C2=C3C4=CC=CC=C4NC3=C5C(=C2C1=O)C6=CC=CC=C6N5[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)OC)O)O	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BPQH98	(3-Chloro-phenyl)-(6,7,8,9-tetrahydro-5H-pyrimido[4,5-b]indol-4-yl)-amine	Investigative	9948215	C16H15ClN4	298.77	C1CCC2=C(C1)C3=C(N2)N=CN=C3NC4=CC(=CC=C4)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BPV4H6	2-(6-((R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy)quinolin-3-yl)cyclopropanecarboxamide	Investigative	46232556	C21H17Cl2FN2O2	419.3	C[C@H](C1=C(C=CC(=C1Cl)F)Cl)OC2=CC3=CC(=CN=C3C=C2)C4CC4C(=O)N	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BQ15CD	N-{4-Methyl-3-[4-(1-oxy-pyridin-3-yl)-pyrimidin-2-ylamino]-phenyl}-benzamide	Investigative	44273555	C23H19N5O2	397.4	CC1=C(C=C(C=C1)NC(=O)C2=CC=CC=C2)NC3=NC=CC(=N3)C4=C[N+](=CC=C4)[O-]	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BQ1Y4B	(5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-m-tolyl-amine	Investigative	10848423	C15H16N4	252.31	CC1=CC(=CC=C1)NC2=NC=NC3=C2C(=C(N3)C)C	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BQV6B2	5-Fluoro-2-[4-[(5-pyridin-4-yl-1,3,4-oxadiazol-2-yl)sulfanylmethyl]phenyl]benzonitrile	Investigative	71578520	C21H13FN4OS	388.4	C1=CC(=CC=C1CSC2=NN=C(O2)C3=CC=NC=C3)C4=C(C=C(C=C4)F)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BQX3F8	2-Amino-7-methyl-4-[(4-methylphenyl)methylamino]-9H-pyrimido[4,5-b]indol-6-ol	Investigative	137659496	C19H19N5O	333.4	CC1=CC=C(C=C1)CNC2=NC(=NC3=C2C4=C(N3)C=C(C(=C4)O)C)N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BQYU75	Modified Benzophenone Carboxylic Acid, Balanol Analog 38	Investigative	5327997	C28H26N2O9	534.5	CC(=O)NC1=C(C(=CC=C1)O)C(=O)C2=C(C=C(C=C2O)C(=O)O[C@@H]3CCC[C@H]3NC(=O)C4=CC=C(C=C4)O)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BR3CS5	N-(3-Bromophenyl)-6,7-dimethoxyquinazolin-4-amine	Investigative	4705	C16H14BrN3O2	360.2	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Br)OC	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BR4Z6X	N-(3-Chlorophenyl)-5-methyl-6-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine	Investigative	10568777	C19H15ClN4	334.8	CC1=C(NC2=C1C(=NC=N2)NC3=CC(=CC=C3)Cl)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BR6PF8	1-Methyl-5-hydroxy-7-methoxy-3-(3-chlorophenyl)quinoline-4(1H)-one	Investigative	9883384	C17H14ClNO3	315.7	CN1C=C(C(=O)C2=C1C=C(C=C2O)OC)C3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BR89XA	5,21-Dichloro-3-[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]-13-methyl-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	10415905	C28H23Cl2N3O7	584.4	CN1C(=O)C2=C3C4=C(C(=CC=C4)Cl)NC3=C5C(=C2C1=O)C6=C(N5[C@H]7[C@@H]([C@H]([C@@H]([C@H](O7)CO)OC)O)O)C(=CC=C6)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BRE9O8	8-Bromo-4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-1,2,3-triazol-4-ylmethyl)amino]quinoline-3-carbonitrile	Investigative	17758019	C19H12BrClFN7	472.7	C1=CC(=C(C=C1NC2=C3C=C(C=C(C3=NC=C2C#N)Br)NCC4=NNN=C4)Cl)F	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BRH24G	1-[(Z)-10-(4-Amino-2-methylquinolin-1-ium-1-yl)dec-5-enyl]-2-methylquinolin-1-ium-4-amine;diiodide	Investigative	10604825	C30H38I2N4	708.5	CC1=[N+](C2=CC=CC=C2C(=C1)N)CCCC/C=C\\CCCC[N+]3=C(C=C(C4=CC=CC=C43)N)C.[I-].[I-]	IC50 = 52000 nM	Poor binder
T12808	Protein kinase C alpha	BRL5J7	[(4R)-3-[(4-Hydroxybenzoyl)amino]azepan-4-yl] 4-(2,6-dihydroxybenzoyl)-3,5-dimethoxybenzoate	Investigative	44322762	C29H30N2O9	550.6	COC1=CC(=CC(=C1C(=O)C2=C(C=CC=C2O)O)OC)C(=O)O[C@@H]3CCCNCC3NC(=O)C4=CC=C(C=C4)O	IC50 ~ 150000 nM	Poor binder
T12808	Protein kinase C alpha	BRN8J1	N-[3-(2-Pyridin-4-ylpyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide	Investigative	24822704	C25H16F3N5O	459.4	C1=CC(=CC(=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C3=CC=NC4=CC(=NN34)C5=CC=NC=C5	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BS0W8Z	2-[4-[[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	57522819	C24H17N3O3S	427.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BS1R6Q	2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[[4-(3-nitrophenyl)phenyl]methylsulfanyl]-1,3,4-oxadiazole	Investigative	71212337	C23H17N3O5S	447.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC(=CC=C5)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BS3G9V	N-{9-[3,4-Dihydroxy-6-(hydroxymethyl)-5-methoxyperhydropyran-2-yl]-1,3-dioxoindolo[2,3-a]3-pyrrolino[3,4-c]carbazol-2-yl}carboxamide	Investigative	465956	C28H24N4O8	544.5	COC1C(OC(C(C1O)O)N2C3=CC=CC=C3C4=C5C(=C6C7=CC=CC=C7NC6=C42)C(=O)N(C5=O)NC=O)CO	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BT45WY	4-Methyl-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide	Investigative	9822042	C24H21N5O	395.5	CC1=CC=C(C=C1)C(=O)NC2=CC(=C(C=C2)C)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BTCQ17	[4-(2,4-Difluoro-5-methoxycarbamoyl-phenylamino)-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazin-6-yl]-carbamic acid 3-methanesulfonyl-propyl ester	Investigative	9893493	C22H26F2N6O6S	540.5	CC(C)C1=C2C(=NC=NN2C=C1NC(=O)OCCCS(=O)(=O)C)NC3=C(C=C(C(=C3)C(=O)NOC)F)F	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BTS9M3	3-[4-[[5-(1,3-Benzodioxol-5-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	71578374	C23H15N3O3S	413.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC(=C5)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BUD4J7	N-[4-Methyl-3-(4-thiophen-2-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Investigative	44273554	C22H18N4OS	386.5	CC1=C(C=C(C=C1)NC(=O)C2=CC=CC=C2)NC3=NC=CC(=N3)C4=CC=CS4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BUK1D4	Methyl 4-[[5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]benzoate	Investigative	70694953	C19H16N2O5S	384.4	COC(=O)C1=CC=C(C=C1)CSC2=NN=C(O2)C3=CC4=C(C=C3)OCCO4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BUW4J8	2-Amino-9-[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyperhydropyran-2-yl]indolo[2,3-a]3-pyrrolino[3,4-c]carbazole-1,3-dione	Investigative	465955	C27H24N4O7	516.5	COC1C(OC(C(C1O)O)N2C3=CC=CC=C3C4=C5C(=C6C7=CC=CC=C7NC6=C42)C(=O)N(C5=O)N)CO	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BV98UM	13-Methyl-3-(3,4,5-trihydroxy-6-methyloxan-2-yl)-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4,6,8,10,15,17,19,21-nonaene-12,14-dione	Investigative	468757	C27H23N3O6	485.5	CC1C(C(C(C(O1)N2C3=CC=CC=C3C4=C5C(=C6C7=CC=CC=C7NC6=C42)C(=O)N(C5=O)C)O)O)O	IC50 = 82000 nM	Poor binder
T12808	Protein kinase C alpha	BVAM65	2-[4-[[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]-5-fluorobenzonitrile	Investigative	57522820	C24H16FN3O3S	445.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=C(C=C(C=C5)F)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BVE28X	2-Cyano-N-[5,21-dihydroxy-12,14-dioxo-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaen-13-yl]acetamide	Investigative	44273605	C29H23N5O10	601.5	C1=CC2=C(C(=C1)O)NC3=C4C(=C5C(=C23)C(=O)N(C5=O)NC(=O)CC#N)C6=C(N4C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 = 65000 nM	Poor binder
T12808	Protein kinase C alpha	BWE0H2	3-[4-[[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	71212291	C24H17N3O3S	427.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC(=C5)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BWOT58	[2-[(4-Hydroxybenzoyl)amino]cyclopentyl] 4-[2-(2-aminoethoxy)-6-hydroxybenzoyl]-3,5-dihydroxybenzoate	Investigative	44322771	C28H28N2O9	536.5	C1CC(C(C1)OC(=O)C2=CC(=C(C(=C2)O)C(=O)C3=C(C=CC=C3OCCN)O)O)NC(=O)C4=CC=C(C=C4)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BX1KF8	5,21-Dihydroxy-13-(propylamino)-3-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-3,13,23-triazahexacyclo[14.7.0.02,10.04,9.011,15.017,22]tricosa-1,4(9),5,7,10,15,17(22),18,20-nonaene-12,14-dione	Investigative	44273600	C29H28N4O9	576.6	CCCNN1C(=O)C2=C3C4=C(C(=CC=C4)O)NC3=C5C(=C2C1=O)C6=C(N5C7C(C(C(C(O7)CO)O)O)O)C(=CC=C6)O	IC50 = 65000 nM	Poor binder
T12808	Protein kinase C alpha	BX5NO4	9-(Azetidin-3-ylamino)-1-phenyl-3,5-dihydro-1H-[1,2,4]triazino[3,4-c][1,4]benzoxazin-2-one	Investigative	118721563	C19H19N5O2	349.4	C1C(CN1)NC2=CC3=C(C=C2)OCC4=NNC(=O)C(N43)C5=CC=CC=C5	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BX80VR	2-(2,3-Dihydro-1,4-benzodioxin-6-yl)-5-[(4-phenylphenyl)methylsulfanyl]-1,3,4-oxadiazole	Investigative	71212419	C23H18N2O3S	402.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BX9B7G	N-Methyl-N-[4-methyl-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide	Investigative	44273559	C24H21N5O	395.5	CC1=C(C=C(C=C1)N(C)C(=O)C2=CC=CC=C2)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 = 85000 nM	Poor binder
T12808	Protein kinase C alpha	BXF62Y	5-{6-[5-(Difluoro-methanesulfonyl-methyl)-[1,3,4]oxadiazol-2-yl]-5-isopropyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino}-2,4-difluoro-N-methoxy-benzamide	Investigative	11432911	C21H19F4N7O5S	557.5	CC(C)C1=C2C(=NC=NN2C=C1C3=NN=C(O3)C(F)(F)S(=O)(=O)C)NC4=C(C=C(C(=C4)C(=O)NOC)F)F	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BY4D7N	(5,6-Dimethyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-phenyl-amine	Investigative	13492269	C14H14N4	238.29	CC1=C(NC2=C1C(=NC=N2)NC3=CC=CC=C3)C	IC50 = 75000 nM	Poor binder
T12808	Protein kinase C alpha	BYH31M	2-(N-[2,6-Dihydroxy-4-[4-[(4-hydroxybenzoyl)amino]pyrrolidin-3-yl]oxycarbonylbenzoyl]anilino)acetic acid	Investigative	44322889	C27H25N3O9	535.5	C1C(C(CN1)OC(=O)C2=CC(=C(C(=C2)O)C(=O)N(CC(=O)O)C3=CC=CC=C3)O)NC(=O)C4=CC=C(C=C4)O	IC50 ~ 150000 nM	Poor binder
T12808	Protein kinase C alpha	BYM2F8	Hydrazinecarboxamide, N-(5,7,12,13-tetrahydro-5,7-dioxo-6H-indolo(2,3-a)pyrrolo(3,4-c)carbazol-6-yl)-	Investigative	465964	C21H14N6O3	398.4	C1=CC=C2C(=C1)C3=C(N2)C4=C(C5=CC=CC=C5N4)C6=C(N(C(=C36)O)NC(=O)N=N)O	IC50 = 78000 nM	Poor binder
T12808	Protein kinase C alpha	BYQU48	4'-({[5-(2H-1,3-Benzodioxol-5-yl)-1,3,4-oxadiazol-2-yl]sulfanyl}methyl)-[1,1'-biphenyl]-2-carbonitrile	Investigative	30291209	C23H15N3O3S	413.4	C1OC2=C(O1)C=C(C=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=CC=C5C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BZ3J6Q	2-[2,6-Dihydroxy-4-[4-[(4-hydroxybenzoyl)amino]pyrrolidin-3-yl]oxycarbonylphenyl]benzoic acid	Investigative	44322954	C25H22N2O8	478.4	C1C(C(CN1)OC(=O)C2=CC(=C(C(=C2)O)C3=CC=CC=C3C(=O)O)O)NC(=O)C4=CC=C(C=C4)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	BZFN71	5-Hydroxy-7-methoxy-3-(3-chlorophenyl)quinoline-4(1H)-one	Investigative	10494548	C16H12ClNO3	301.72	COC1=CC2=C(C(=C1)O)C(=O)C(=CN2)C3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BZM1D2	4-[4-[[5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,3,4-oxadiazol-2-yl]sulfanylmethyl]phenyl]benzonitrile	Investigative	71212233	C24H17N3O3S	427.5	C1COC2=C(O1)C=CC(=C2)C3=NN=C(O3)SCC4=CC=C(C=C4)C5=CC=C(C=C5)C#N	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	BZNF82	2-Methoxy-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide	Investigative	10136330	C24H21N5O2	411.5	CC1=C(C=C(C=C1)NC(=O)C2=CC=CC=C2OC)NC3=NC=CC(=N3)C4=CN=CC=C4	IC50 = 80000 nM	Poor binder
T12808	Protein kinase C alpha	BZY43J	[2-[(4-Hydroxybenzoyl)amino]cyclopentyl] 4-(2-acetamido-6-hydroxybenzoyl)-3,5-dihydroxybenzoate	Investigative	44322814	C28H26N2O9	534.5	CC(=O)NC1=C(C(=CC=C1)O)C(=O)C2=C(C=C(C=C2O)C(=O)OC3CCCC3NC(=O)C4=CC=C(C=C4)O)O	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	D02XHC	aloisine A	Investigative	448912	C16H17N3O	267.33	CCCCC1=C(NC2=NC=CN=C12)C3=CC=C(C=C3)O	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	D03MUZ	8-chloro-quinoline-3-carbonitrile	Investigative	17759555	C20H13Cl2FN6	427.3	C1=CC(=C(C=C1NC2=C3C=C(C=C(C3=NC=C2C#N)Cl)NCC4=CN=CN4)Cl)F	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	D09XIL	Ro-4396686	Investigative	11396738	C24H24FN5O3	449.5	COC1=CC=C(C=C1)N2CC3=CN=C(N=C3N(C2=O)[C@@H]4CC[C@H](C4)O)NC5=CC=C(C=C5)F	IC50 ~ 125000 nM	Poor binder
T12808	Protein kinase C alpha	D0C9KC	3-(3-Chloro-phenyl)-5,7-dihydroxy-chromen-4-one	Investigative	10850934	C15H9ClO4	288.68	C1=CC(=CC(=C1)Cl)C2=COC3=CC(=CC(=C3C2=O)O)O	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	D0M9QM	CGP-191	Investigative	5327820	C17H13N5	287.32	C1=CC=C(C=C1)C2=NN(C3=NC=NC(=C23)N)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T12808	Protein kinase C alpha	D0W7TU	NSC-73306	Investigative	947057	C16H14N4O2S	326.4	.	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	D0Z7TM	BMS-645737	Investigative	22273644	C20H20N8O	388.4	CC1=CC2=CC(=CN=C2N1)NC3=NC=NN4C3=C(C(=C4)C5=NN=C(O5)C)C(C)C	IC50 ~ 50000 nM	Poor binder
T12808	Protein kinase C alpha	D0ZH1U	TYRPHOSTIN AG-1478	Investigative	2051	C16H14ClN3O2	315.75	COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)Cl)OC	IC50 ~ 100000 nM	Poor binder