TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T13057	Protein-tyrosine phosphatase SHP-2	B0BZ5V	5-(1H-Indol-3-ylmethyl)-3-[6-(3-methylphenyl)pyridin-2-yl]-1,2,4-oxadiazole	Investigative	127028684	C23H18N4O	366.4	CC1=CC(=CC=C1)C2=NC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B0KC2T	3-[6-(4-Ethoxyphenyl)pyridin-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127028686	C24H20N4O2	396.4	CCOC1=CC=C(C=C1)C2=NC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B0MOW9	3-[2-(2,4-Dichlorophenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid	Investigative	135971768	C14H9Cl2N3O4S	386.2	C1=CC2=C(C=C1S(=O)(=O)O)C(=C(N2)O)N=NC3=C(C=C(C=C3)Cl)Cl	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B0O3TJ	N-[(3-Methoxyphenyl)methyl]-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide	Investigative	135971733	C22H19N5O6S	481.5	COC1=CC=CC(=C1)CNS(=O)(=O)C2=CC3=C(C=C2)NC(=C3N=NC4=CC=CC=C4[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B0RP6O	2-Oxo-3-(2-phenylhydrazinyl)indole-5-sulfonic acid	Investigative	135971777	C14H11N3O4S	317.32	C1=CC=C(C=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B0S1RB	3-[(3-Nitrophenyl)diazenyl]-1H-indol-2-ol	Investigative	5240714	C14H10N4O3	282.25	C1=CC=C2C(=C1)C(=C(N2)O)N=NC3=CC(=CC=C3)[N+](=O)[O-]	IC50 ~ 60000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B13SCI	(2S,3S)-2-[[(3S,6S,9S,12S,15S)-3-Benzyl-12-[(2S)-butan-2-yl]-6-(1H-indol-3-ylmethyl)-7-methyl-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-1,4,7,10,13-pentazacyclononadec-15-yl]carbamoylamino]-3-methylpentanoic acid	Investigative	11844603	C46H66N8O8	859.1	CC[C@H](C)[C@H]1C(=O)N[C@H](C(=O)N([C@H](C(=O)N[C@H](C(=O)NCCCC[C@@H](C(=O)N1)NC(=O)N[C@@H]([C@@H](C)CC)C(=O)O)CC2=CC=CC=C2)CC3=CNC4=CC=CC=C43)C)CC(C)C	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B15PRL	5-(1H-Indol-3-ylmethyl)-3-[3-(4-propoxyphenyl)phenyl]-1,2,4-oxadiazole	Investigative	127028346	C26H23N3O2	409.5	CCCOC1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B1BZT4	6-[(3-Sulfophenyl)carbamoyl]naphthalene-2-carboxylic acid	Investigative	59762958	C18H13NO6S	371.4	C1=CC(=CC(=C1)S(=O)(=O)O)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B1GU8P	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(pyridin-4-ylmethyl)-1H-indole-5-sulfonamide	Investigative	135971794	C20H16ClN5O3S	441.9	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=NC=C4)O)Cl	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B1GV8N	US8987474, Rpm332	Investigative	135971688	C24H24N6O4S	492.6	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC(=C3)C(=O)NCC4=CN=CC=C4)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B1T7YO	5-[(6-Carboxynaphthalene-2-carbonyl)amino]benzene-1,3-dicarboxylic acid	Investigative	59762970	C20H13NO7	379.3	C1=CC2=C(C=CC(=C2)C(=O)O)C=C1C(=O)NC3=CC(=CC(=C3)C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B1UB3L	3-[2-(2-Ethylphenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid	Investigative	135971747	C16H15N3O4S	345.4	CCC1=CC=CC=C1N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)O)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B1XQB4	3-[2-(2-Nitrophenyl)hydrazinyl]-2-oxo-N-propylindole-5-sulfonamide	Investigative	135971762	C17H17N5O5S	403.4	CCCNS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B1Z4EK	US8987474, Rpm310	Investigative	135971687	C22H17ClN4O5S	484.9	C1=CC=C(C(=C1)N=CC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=C(C=C4)Cl)O)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B20KQZ	4-[3-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]phenol	Investigative	127027703	C23H17N3O2	367.4	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC=CC(=C4)C5=CC=C(C=C5)O	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B21JFB	N-(2-Methoxyethyl)-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide	Investigative	135971691	C21H25N5O5S	459.5	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3C(=O)NCCOC)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B21KXO	N-Benzyl-N-methyl-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide	Investigative	135971773	C22H19N5O5S	465.5	CN(CC1=CC=CC=C1)S(=O)(=O)C2=CC3=C(C=C2)NC(=C3N=NC4=CC=CC=C4[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B2HQA0	US8987474, Rpm191	Investigative	135971754	C22H17ClN4O5S	484.9	C1=CC=C(C(=C1)C(=O)O)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=C(C=C4)Cl)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B2IX3L	N-{2-[4-(4-Fluorophenyl)piperazin-1-yl]-1-methyl-2-thien-2-ylethyl}-N'-(pyridin-3-ylmethyl)ethanediamide	Investigative	20866464	C25H28FN5O2S	481.6	CC(C(C1=CC=CS1)N2CCN(CC2)C3=CC=C(C=C3)F)NC(=O)C(=O)NCC4=CN=CC=C4	IC50 ~ 50000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B2N9PK	2-[2-[2-Oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide	Investigative	135971742	C18H19N5O4S	401.4	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3C(=O)N)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B2Q4RY	(2S)-2-[[(2S,3S)-2-[[(2S)-4-Carboxy-2-[[(2S)-4-carboxy-2-[[2-phenyl-3-(4-phosphonooxyphenyl)propanoyl]amino]butanoyl]amino]butanoyl]amino]-3-methylpentanoyl]amino]pentanedioic acid	Investigative	70691280	C36H47N4O16P	822.7	CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)C(CC1=CC=C(C=C1)OP(=O)(O)O)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B2Q8VW	3-[2-(2,5-Dichlorophenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid	Investigative	135971776	C14H9Cl2N3O4S	386.2	C1=CC2=C(C=C1S(=O)(=O)O)C(=C(N2)O)N=NC3=C(C=CC(=C3)Cl)Cl	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B2TER8	N-Benzyl-3-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide	Investigative	135971727	C25H25N5O4S	491.6	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC(=C3)C(=O)NCC4=CC=CC=C4)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B2XVS3	2-(3-Bromoanilino)-5-hydroxybenzothiazole-6-carboxylic acid	Investigative	101884098	C14H9BrN2O3S	365.2	C1=CC(=CC(=C1)Br)NC2=NC3=C(S2)C=C(C(=C3)O)C(=O)O	IC50 = 50000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B36JDQ	(S)-2-(4-(Benzamidomethyl)-1H-1,2,3-triazol-1-yl)-3-(4-hydroxyphenyl)propanoic acid	Investigative	53320581	C19H18N4O4	366.4	C1=CC=C(C=C1)C(=O)NCC2=CN(N=N2)[C@@H](CC3=CC=C(C=C3)O)C(=O)O	IC50 ~ 50000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B3GM4U	[(4-{4-[4-(Difluoro-phosphono-methyl)-phenyl]-butyl}-phenyl)-difluoro-methyl]-phosphonic acid	Investigative	446665	C18H20F4O6P2	470.3	C1=CC(=CC=C1CCCCC2=CC=C(C=C2)C(F)(F)P(=O)(O)O)C(F)(F)P(=O)(O)O	IC50 = 91000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B3IP0Z	US8987474, Rpm290	Investigative	135971703	C24H24N6O4S	492.6	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3C(=O)NCC4=CN=CC=C4)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B3P0MR	3-[(2-Nitroanilino)methylidene]-2-oxo-N-propan-2-yl-1H-indole-5-sulfonamide	Investigative	135971755	C18H18N4O5S	402.4	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2C=NC3=CC=CC=C3[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B3VYR4	5-(1H-Indol-3-ylmethyl)-3-[5-(3-methylphenyl)thiophen-2-yl]-1,2,4-oxadiazole	Investigative	127025572	C22H17N3OS	371.5	CC1=CC(=CC=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B48NCB	3-[2-(2-Methylphenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid	Investigative	135971757	C15H13N3O4S	331.3	CC1=CC=CC=C1N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B4A6YV	US8987474, Rpm195	Investigative	59763034	C18H14N2O5S	370.4	C1=CC(=CC=C1NC(=O)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B4DRW6	2-[3-(3-Carboxypropanoylamino)phenyl]-6-hydroxy-3-iodo-1-methylindole-5-carboxylic acid	Investigative	118709489	C20H17IN2O6	508.3	CN1C2=CC(=C(C=C2C(=C1C3=CC(=CC=C3)NC(=O)CCC(=O)O)I)C(=O)O)O	IC50 = 56000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B4J6AP	3-[(2-Chlorophenyl)diazenyl]-N-(furan-2-ylmethyl)-2-hydroxy-1H-indole-5-sulfonamide	Investigative	135971740	C19H15ClN4O4S	430.9	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=CO4)O)Cl	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B4N9VB	5-(1H-Indol-3-ylmethyl)-3-[5-(4-propylphenyl)thiophen-2-yl]-1,2,4-oxadiazole	Investigative	127025574	C24H21N3OS	399.5	CCCC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B5AS2X	3-(1,3-Benzothiazol-2-yldiazenyl)-2-hydroxy-1H-indole-5-sulfonic acid	Investigative	135971693	C15H10N4O4S2	374.4	C1=CC=C2C(=C1)N=C(S2)N=NC3=C(NC4=C3C=C(C=C4)S(=O)(=O)O)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B5FW8T	3-{2-[(3Z)-5-{[(4-Chlorophenyl)methyl]carbamoyl}-2-oxo-2,3-dihydro-1H-indol-3-ylidene]hydrazin-1-yl}benzoic acid	Investigative	135924023	C23H17ClN4O4	448.9	C1=CC(=CC(=C1)N=NC2=C(NC3=C2C=C(C=C3)C(=O)NCC4=CC=C(C=C4)Cl)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B5I0AF	(2S)-3-[[1-[[(2R,3S,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid	Investigative	56680547	C39H48N4O10	732.8	CC(C)(C)OC(=O)N[C@@H](COCC1=CN(N=N1)C[C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)C(=O)O	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B5J8FA	N-Methyl-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide	Investigative	135971752	C19H21N5O4S	415.5	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3C(=O)NC)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B5MK2U	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(2-methylpropyl)-1H-indole-5-sulfonamide	Investigative	135971763	C18H19ClN4O3S	406.9	CC(C)CNS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3Cl)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B5OTE7	3-[[2-Oxo-5-(propan-2-ylsulfamoyl)-1H-indol-3-ylidene]methylamino]benzoic acid	Investigative	135971713	C19H19N3O5S	401.4	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2C=NC3=CC=CC(=C3)C(=O)O)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B63XDV	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-[(3-methoxyphenyl)methyl]-1H-indole-5-sulfonamide	Investigative	135971705	C22H19ClN4O4S	470.9	COC1=CC=CC(=C1)CNS(=O)(=O)C2=CC3=C(C=C2)NC(=C3N=NC4=CC=CC=C4Cl)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B6IA7E	(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2R)-2-Acetamido-3-(4-phosphonooxyphenyl)propanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-methylpentanoyl]amino]pentanedioic acid	Investigative	44324648	C32H46N5O17P	803.7	CC[C@H](C)[C@@H](C(=O)N[C@@H](CCC(=O)O)C(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](CC1=CC=C(C=C1)OP(=O)(O)O)NC(=O)C	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B6M9RJ	Ethyl 4-[[2-oxo-5-(propan-2-ylsulfamoyl)-1H-indol-3-ylidene]methylamino]benzoate	Investigative	135971738	C21H23N3O5S	429.5	CCOC(=O)C1=CC=C(C=C1)N=CC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NC(C)C)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B6Q7TJ	5-(1H-Indol-3-ylmethyl)-3-[3-(4-propylphenyl)phenyl]-1,2,4-oxadiazole	Investigative	127027706	C26H23N3O	393.5	CCCC1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B6SRJ7	US8987474, Rpm284	Investigative	135971719	C22H28N6O4S	472.6	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3C(=O)NCCN(C)C)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B6XVK1	US8987474, Rpm177	Investigative	135971692	C18H17N5O6S	431.4	C1COCCN1S(=O)(=O)C2=CC3=C(C=C2)NC(=C3N=NC4=CC=CC=C4[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B78AGS	2-[2-(2-Oxo-5-sulfamoylindol-3-yl)hydrazinyl]benzoic acid	Investigative	135971702	C15H12N4O5S	360.3	C1=CC=C(C(=C1)C(=O)O)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)N)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B78JWS	US8987474, Rpm202	Investigative	59762919	C20H15NO6	365.3	COC(=O)C1=CC2=C(C=C1)C=C(C=C2)C(=O)NC3=C(C=CC=C3O)C(=O)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B79XZG	3-(3-Bromophenyl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127027399	C17H12BrN3O	354.2	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC(=CC=C4)Br	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B7IZ9G	US8987474, Rpm185	Investigative	59762965	C20H15NO5	349.3	COC(=O)C1=CC2=C(C=C1)C=C(C=C2)C(=O)NC3=CC=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B7KA2Y	5-(1H-Indol-3-ylmethyl)-3-[5-(4-propoxyphenyl)thiophen-2-yl]-1,2,4-oxadiazole	Investigative	127025577	C24H21N3O2S	415.5	CCCOC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B86FMP	Triazole tetra-benzyloxy-beta-D-O-glucosyl Threonine	Investigative	53316640	C41H47N3O8	709.8	C[C@H]([C@@H](CO)N1C=C(N=N1)CO[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)COCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)OCC6=CC=CC=C6)O	IC50 ~ 50000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B8EFQ5	US8987474, Rpm156	Investigative	135971729	C23H21N5O5S	479.5	CN(C)S(=O)(=O)C1=CC2=C(C=C1)N(C(=C2N=NC3=CC=CC=C3[N+](=O)[O-])O)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B8KY0P	US8987474, Rpm319	Investigative	136633308	C15H9FN2O4	300.24	C1=CC=C(C(=C1)N=NC2=C(OC3=C2C=C(C=C3)C(=O)O)O)F	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B8L2IV	2-[2-(2-Oxo-5-sulfoindol-3-yl)hydrazinyl]benzoic acid	Investigative	135971790	C15H11N3O6S	361.3	C1=CC=C(C(=C1)C(=O)O)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)O)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B8MSX2	Sodium;(2S)-2-[[[ethoxy(hydroxy)phosphoryl]-(2-hydroxyphenyl)methyl]amino]-3-hydroxypropanoate	Investigative	57380433	C12H17NNaO7P	341.23	CCOP(=O)(C(C1=CC=CC=C1O)N[C@@H](CO)C(=O)[O-])O.[Na+]	IC50 = 191000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B8TK9P	4-[5-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]thiophen-2-yl]aniline	Investigative	118722143	C21H16N4OS	372.4	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC=C(S4)C5=CC=C(C=C5)N	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B94ALM	2-[(5-Isopropylsulfamoyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)amino]benzoic acid methyl ester	Investigative	135971720	C20H21N3O5S	415.5	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2C=NC3=CC=CC=C3C(=O)OC)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B98COY	N-Benzyl-3-[(2-chlorophenyl)diazenyl]-2-hydroxy-N-methyl-1H-indole-5-sulfonamide	Investigative	135971718	C22H19ClN4O3S	454.9	CN(CC1=CC=CC=C1)S(=O)(=O)C2=CC3=C(C=C2)NC(=C3N=NC4=CC=CC=C4Cl)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B9H3QW	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-1H-indole-5-sulfonic acid	Investigative	135971764	C14H10ClN3O4S	351.8	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)O)O)Cl	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B9J7KO	4-[3-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]aniline	Investigative	118722144	C23H18N4O	366.4	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC=CC(=C4)C5=CC=C(C=C5)N	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B9NUQ0	(2S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[[1-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]triazol-4-yl]methoxy]propanoic acid	Investigative	56670423	C17H28N4O10	448.4	CC(C)(C)OC(=O)N[C@@H](COCC1=CN(N=N1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)C(=O)O	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B9OQ6W	Triazole tetra-benzyloxy-beta-D-O-glucosyl Serine	Investigative	53317937	C40H43N3O9	709.8	C1=CC=C(C=C1)COC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OCC3=CN(N=N3)[C@@H](CO)C(=O)O)OCC4=CC=CC=C4)OCC5=CC=CC=C5)OCC6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B9PNV5	(2S)-3-[[1-[[(2R,3R,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid	Investigative	56660070	C39H48N4O10	732.8	CC(C)(C)OC(=O)N[C@@H](COCC1=CN(N=N1)C[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)C(=O)O	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	B9WH2L	Indole-2, 3-[(o-chlorophenyl)hydrazone]	Investigative	272589	C14H10ClN3O	271.7	C1=CC=C2C(=C1)C(=C(N2)O)N=NC3=CC=CC=C3Cl	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BA2PB3	US8987474, Rpm293	Investigative	135971699	C24H30N6O5S	514.6	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3C(=O)NCCN4CCOCC4)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BA2ZM3	3-(5-Bromothiophen-2-yl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127027398	C15H10BrN3OS	360.2	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC=C(S4)Br	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BA50MW	2,2,6,6-Tetramethyl-N-(4-phenyl-1,3-thiazol-2-yl)piperidin-4-amine	Investigative	25640845	C18H25N3S	315.5	CC1(CC(CC(N1)(C)C)NC2=NC(=CS2)C3=CC=CC=C3)C	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BA6D0U	Ethyl 3-[[2-oxo-5-(propan-2-ylsulfamoyl)-1H-indol-3-ylidene]methylamino]benzoate	Investigative	135971736	C21H23N3O5S	429.5	CCOC(=O)C1=CC(=CC=C1)N=CC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NC(C)C)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BA98DC	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N,N-dimethyl-1H-indole-5-sulfonamide	Investigative	135971789	C16H15ClN4O3S	378.8	CN(C)S(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3Cl)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BB15ZO	3-[2-(2-Nitrophenyl)hydrazinyl]-2-oxo-N-(oxolan-2-ylmethyl)indole-5-sulfonamide	Investigative	135971726	C19H19N5O6S	445.5	C1CC(OC1)CNS(=O)(=O)C2=CC3=C(C=C2)NC(=C3N=NC4=CC=CC=C4[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BBG3J0	2-[2-(2-Oxoindol-3-yl)hydrazinyl]benzoic Acid	Investigative	3784946	C15H11N3O3	281.27	C1=CC=C2C(=C1)C(=C(N2)O)N=NC3=CC=CC=C3C(=O)O	IC50 ~ 60000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BCQ27J	5-(1H-Indol-3-ylmethyl)-3-[6-(2-methylphenyl)pyridin-2-yl]-1,2,4-oxadiazole	Investigative	127028683	C23H18N4O	366.4	CC1=CC=CC=C1C2=NC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BCZR81	2-Oxo-3-(2-phenylhydrazinyl)indole-5-carboxylic acid	Investigative	135971750	C15H11N3O3	281.27	C1=CC=C(C=C1)N=NC2=C(NC3=C2C=C(C=C3)C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BD04NS	2-Hydroxy-5-[4-[4-[[(2R,3R,4S,5R,6S)-3,4,5-tribenzoyloxy-6-methoxyoxan-2-yl]methoxymethyl]triazol-1-yl]butoxy]benzoic acid	Investigative	56681854	C42H41N3O13	795.8	CO[C@@H]1[C@@H]([C@H]([C@@H]([C@H](O1)COCC2=CN(N=N2)CCCCOC3=CC(=C(C=C3)O)C(=O)O)OC(=O)C4=CC=CC=C4)OC(=O)C5=CC=CC=C5)OC(=O)C6=CC=CC=C6	IC50 = 54300 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BD26ER	(2S,3S)-3-[[1-[[(2R,3S,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid	Investigative	56683882	C40H50N4O10	746.8	C[C@@H]([C@@H](C(=O)O)NC(=O)OC(C)(C)C)OCC1=CN(N=N1)C[C@@H]2[C@@H]([C@@H]([C@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BD2C7S	N-(2-Methoxyethyl)-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide	Investigative	135971721	C17H17N5O6S	419.4	COCCNS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BD3A8G	N,N-Diethyl-2-hydroxy-3-[(2-nitrophenyl)diazenyl]-1H-indole-5-carboxamide	Investigative	135971710	C19H19N5O4	381.4	CCN(CC)C(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BD5G7T	3-[5-(4-Ethylphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127025573	C23H19N3OS	385.5	CCC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BD7HQ1	(2E,5E)-5-[(4-Chlorophenyl)methylidene]-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-one	Investigative	135445085	C13H8ClN3OS2	321.8	C1=CC(=CC=C1/C=C/2\\C(=O)N/C(=N\\C3=NC=CS3)/S2)Cl	Ki = 54500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BD8LC6	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(pyridin-2-ylmethyl)-1H-indole-5-sulfonamide	Investigative	135971791	C20H16ClN5O3S	441.9	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=CC=N4)O)Cl	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BDB79G	Ethyl 2-[[5-[4-(3-chlorophenyl)piperazin-1-yl]sulfonyl-2,3-dihydroindole-1-carbonyl]amino]acetate	Investigative	44624819	C23H27ClN4O5S	507	CCOC(=O)CNC(=O)N1CCC2=C1C=CC(=C2)S(=O)(=O)N3CCN(CC3)C4=CC(=CC=C4)Cl	IC50 = 60300 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BDZ50R	3-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)naphthalen-2-ol	Investigative	134131790	C13H8F6O2	310.19	C1=CC=C2C=C(C(=CC2=C1)C(C(F)(F)F)(C(F)(F)F)O)O	IC50 = 114800 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BE3K5V	US8987474, HL2-026-Intermediate	Investigative	59762974	C23H19NO7	421.4	COC(=O)C1=CC2=C(C=C1)C=C(C=C2)C(=O)NC3=CC(=CC(=C3)C(=O)OC)C(=O)OC	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BE8S7U	(2S,3S)-2-[[(3S,6R,9S,12S,15S)-3-Benzyl-6-[2-[2-(carbamoylamino)phenyl]-2-oxoethyl]-7-methyl-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-12-propan-2-yl-1,4,7,10,13-pentazacyclononadec-15-yl]carbamoylamino]-3-methylpentanoic acid	Investigative	44415112	C45H65N9O10	892.1	CC[C@H](C)[C@@H](C(=O)O)NC(=O)N[C@H]1CCCCNC(=O)[C@@H](NC(=O)[C@H](N(C(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)CC(C)C)C)CC(=O)C2=CC=CC=C2NC(=O)N)CC3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BE8SR4	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(pyridin-3-ylmethyl)-1H-indole-5-sulfonamide	Investigative	135971732	C20H16ClN5O3S	441.9	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CN=CC=C4)O)Cl	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BE9VH5	2-[(5-Isopropylsulfamoyl-2-oxo-1,2-dihydro-indol-3-ylidenemethyl)amino]benzoic acid	Investigative	135971734	C19H19N3O5S	401.4	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2C=NC3=CC=CC=C3C(=O)O)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BEF67A	3-(6-Bromopyridin-2-yl)-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127027724	C16H11BrN4O	355.19	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=NC(=CC=C4)Br	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BF46RU	N-[(4-Chlorophenyl)methyl]-2-oxo-1,3-dihydroindole-5-sulfonamide	Investigative	59762990	C15H13ClN2O3S	336.8	C1C2=C(C=CC(=C2)S(=O)(=O)NCC3=CC=C(C=C3)Cl)NC1=O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BF5EV1	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(oxolan-2-ylmethyl)-1H-indole-5-sulfonamide	Investigative	135971781	C19H19ClN4O4S	434.9	C1CC(OC1)CNS(=O)(=O)C2=CC3=C(C=C2)NC(=C3N=NC4=CC=CC=C4Cl)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BF7ZA0	Methyl 4-[4-[5-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]thiophen-2-yl]phenoxy]butanoate	Investigative	127025578	C26H23N3O4S	473.5	COC(=O)CCCOC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BFTO82	(2S,3S)-2-[[(3S,6S,9S,12S,15S)-3-Benzyl-6-(1H-indol-3-ylmethyl)-7-methyl-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-12-propan-2-yl-1,4,7,10,13-pentazacyclononadec-15-yl]carbamoylamino]-3-methylpentanoic acid	Investigative	11844604	C45H64N8O8	845	CC[C@H](C)[C@@H](C(=O)O)NC(=O)N[C@H]1CCCCNC(=O)[C@@H](NC(=O)[C@@H](N(C(=O)[C@@H](NC(=O)[C@@H](NC1=O)C(C)C)CC(C)C)C)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BFXO31	2-Hydroxy-3-[(2-nitrophenyl)diazenyl]-N-(pyridin-3-ylmethyl)-1H-indole-5-sulfonamide	Investigative	135971707	C20H16N6O5S	452.4	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CN=CC=C4)O)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BGOP20	3-[5-(4-Ethoxyphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127025576	C23H19N3O2S	401.5	CCOC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BGQ5Z0	4-[6-[5-(1H-Indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]pyridin-2-yl]phenol	Investigative	137174949	C22H16N4O2	368.4	C1=CC=C2C(=C1)C(=CN2)CC3=NC(=NO3)C4=CC=CC(=N4)C5=CC=C(C=C5)O	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BHDY24	3-[2-(2-Nitrophenyl)hydrazinyl]-2-oxo-N-(pyridin-4-ylmethyl)indole-5-sulfonamide	Investigative	135971751	C20H16N6O5S	452.4	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=NC=C4)O)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BHQ0B6	1-Ethyl-N,N-dimethyl-3-[(2-nitrophenyl)hydrazinylidene]-2-oxoindole-5-sulfonamide	Investigative	135971739	C18H19N5O5S	417.4	CCN1C2=C(C=C(C=C2)S(=O)(=O)N(C)C)C(=C1O)N=NC3=CC=CC=C3[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BI15JX	2-Hydroxy-3-[(2-nitrophenyl)diazenyl]-1H-indole-5-carboxylic acid	Investigative	135857165	C15H10N4O5	326.26	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)C(=O)O)O)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BI8C5R	3-[3-(4-Ethoxyphenyl)phenyl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127028022	C25H21N3O2	395.5	CCOC1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BI95BZ	Triazole tetra-benzyloxy-beta-D-O-glucosyl Tyrosine	Investigative	53320578	C41H45N3O9	723.8	C[C@H]([C@@H](C(=O)O)N1C=C(N=N1)CO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)OCC6=CC=CC=C6)O	IC50 ~ 50000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BIJ8R3	US8987474, Rpm333	Investigative	135971714	C23H23N5O5S	481.5	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC(=C3)C(=O)NCC4=CC=CO4)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BITB59	2-Hydroxy-3-[(3-nitrophenyl)diazenyl]-1H-indole-5-sulfonic acid	Investigative	135971774	C14H10N4O6S	362.32	C1=CC(=CC(=C1)[N+](=O)[O-])N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)O)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BIV50Y	4-[[2-Oxo-5-(propan-2-ylsulfamoyl)-1H-indol-3-ylidene]methylamino]benzoic acid	Investigative	135971728	C19H19N3O5S	401.4	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2C=NC3=CC=C(C=C3)C(=O)O)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BJ8RB2	2-Oxo-3-[2-(2,3,4,5,6-pentafluorophenyl)hydrazinyl]indole-5-sulfonic acid	Investigative	135971772	C14H6F5N3O4S	407.27	C1=CC2=C(C=C1S(=O)(=O)O)C(=C(N2)O)N=NC3=C(C(=C(C(=C3F)F)F)F)F	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BJP2O3	3-(2-Naphthalen-1-ylhydrazinyl)-2-oxoindole-5-sulfonic acid	Investigative	135971704	C18H13N3O4S	367.4	C1=CC=C2C(=C1)C=CC=C2N=NC3=C(NC4=C3C=C(C=C4)S(=O)(=O)O)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BJUL08	(S)-3-Hydroxy-2-(4-(((2R,3R,4S,5S,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yloxy)methyl)-1H-1,2,3-triazol-1-yl)propanoic acid	Investigative	53324565	C40H43N3O9	709.8	C1=CC=C(C=C1)COC[C@@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)OCC3=CN(N=N3)[C@@H](CO)C(=O)O)OCC4=CC=CC=C4)OCC5=CC=CC=C5)OCC6=CC=CC=C6	IC50 ~ 50000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BK52NL	6-(Phenylcarbamoyl)naphthalene-2-carboxylic acid	Investigative	57390877	C18H13NO3	291.3	C1=CC=C(C=C1)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BK5UV3	Methyl 4-[4-[3-[5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazol-3-yl]phenyl]phenoxy]butanoate	Investigative	127028347	C28H25N3O4	467.5	COC(=O)CCCOC1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BKDP53	(2E,5E)-5-[(4-Hydroxy-3-methoxyphenyl)methylidene]-2-[(4-phenyl-1,3-thiazol-2-yl)imino]-1,3-thiazolidin-4-one	Investigative	135924159	C20H15N3O3S2	409.5	COC1=C(C=CC(=C1)/C=C/2\\C(=O)N/C(=N\\C3=NC(=CS3)C4=CC=CC=C4)/S2)O	Ki = 103200 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BKO4Z1	5-(1H-Indol-3-ylmethyl)-3-[3-(3-methylphenyl)phenyl]-1,2,4-oxadiazole	Investigative	127027705	C24H19N3O	365.4	CC1=CC(=CC=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BKRQ36	6-Hydroxy-3-(3-hydroxyprop-1-ynyl)-2-phenyl-benzofuran-5-carboxylic acid	Investigative	71561559	C18H12O5	308.3	C1=CC=C(C=C1)C2=C(C3=CC(=C(C=C3O2)O)C(=O)O)C#CCO	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BKX3E9	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(morpholin-4-ylmethyl)-1H-indole-5-sulfonamide	Investigative	135971696	C19H20ClN5O4S	449.9	C1COCCN1CNS(=O)(=O)C2=CC3=C(C=C2)NC(=C3N=NC4=CC=CC=C4Cl)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BKX5J1	3-[2-(2-Fluorophenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid	Investigative	135971782	C14H10FN3O4S	335.31	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)O)O)F	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BKZ7N1	3-[2-[2-Oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide	Investigative	135971690	C18H19N5O4S	401.4	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC(=C3)C(=O)N)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BL14TM	US8987474, Rpm270	Investigative	135971756	C15H10ClN3O3	315.71	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)C(=O)O)O)Cl	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BL4UN9	N-[2-(Dimethylamino)ethyl]-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide	Investigative	135971698	C18H20N6O5S	432.5	CN(C)CCNS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BLE90X	3-[(2-Chlorophenyl)diazenyl]-N-[(4-chlorophenyl)methyl]-2-hydroxy-1H-indole-5-sulfonamide	Investigative	135971712	C21H16Cl2N4O3S	475.3	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=C(C=C4)Cl)O)Cl	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BLH30U	N,N-Dimethyl-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide	Investigative	135971760	C16H15N5O5S	389.4	CN(C)S(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3[N+](=O)[O-])O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BLW2C4	3-[[2-Hydroxy-5-(propan-2-ylcarbamoyl)-1H-indol-3-yl]diazenyl]benzoic acid	Investigative	135971770	C19H18N4O4	366.4	CC(C)NC(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC(=C3)C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BM2G4S	3-[5-(4-Butylphenyl)thiophen-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127025575	C25H23N3OS	413.5	CCCCC1=CC=C(C=C1)C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BMAP17	US8987474, Rpm204	Investigative	59762908	C19H13NO6	351.3	C1=CC(=C(C(=C1)O)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C(=O)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BMP81E	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(thiophen-2-ylmethyl)-1H-indole-5-sulfonamide	Investigative	135971735	C19H15ClN4O3S2	446.9	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=CS4)O)Cl	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BMU1Q4	US8987474, Rpm292	Investigative	135971746	C23H23N5O5S	481.5	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3C(=O)NCC4=CC=CO4)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BN13ST	N-Ethyl-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide	Investigative	135971745	C20H23N5O4S	429.5	CCNC(=O)C1=CC=CC=C1N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NC(C)C)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BN8H0T	2-[[5-(Diethylcarbamoyl)-2-hydroxy-1H-indol-3-yl]diazenyl]benzoic acid	Investigative	135971686	C20H20N4O4	380.4	CCN(CC)C(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BNG14E	3-[3-(4-Butylphenyl)phenyl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127027707	C27H25N3O	407.5	CCCCC1=CC=C(C=C1)C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BNJ0V9	2-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-6-phenylphenol	Investigative	134148434	C15H10F6O2	336.23	C1=CC=C(C=C1)C2=C(C(=CC=C2)C(C(F)(F)F)(C(F)(F)F)O)O	IC50 = 136000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BNKS16	(2S,3S)-2-[(2-Methylpropan-2-yl)oxycarbonylamino]-3-[[1-[(2R,3R,4S,5R,6R)-3,4,5-tris(phenylmethoxy)-6-(phenylmethoxymethyl)oxan-2-yl]triazol-4-yl]methoxy]butanoic acid	Investigative	56673908	C46H54N4O10	822.9	C[C@@H]([C@@H](C(=O)O)NC(=O)OC(C)(C)C)OCC1=CN(N=N1)[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)COCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)OCC6=CC=CC=C6	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BNPK29	N,N'-4,4'-Biphenyldiyldi(2-furamide)	Investigative	998012	C22H16N2O4	372.4	C1=COC(=C1)C(=O)NC2=CC=C(C=C2)C3=CC=C(C=C3)NC(=O)C4=CC=CO4	IC50 = 52070 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BO3CM2	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-[(4-methoxyphenyl)methyl]-1H-indole-5-sulfonamide	Investigative	135971778	C22H19ClN4O4S	470.9	COC1=CC=C(C=C1)CNS(=O)(=O)C2=CC3=C(C=C2)NC(=C3N=NC4=CC=CC=C4Cl)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BO9TI7	3-[2-(2-Nitrophenyl)hydrazinyl]-2-oxo-N-(thiophen-2-ylmethyl)indole-5-sulfonamide	Investigative	135971694	C19H15N5O5S2	457.5	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=CS4)O)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BOA31L	5-(1H-Indol-3-ylmethyl)-3-[3-(2-methylphenyl)phenyl]-1,2,4-oxadiazole	Investigative	127027704	C24H19N3O	365.4	CC1=CC=CC=C1C2=CC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BOEU56	3,4,6-Tribromo-5-[(2,3,6-tribromo-4,5-dihydroxyphenyl)methyl]benzene-1,2-diol	Investigative	21778115	C13H6Br6O4	705.6	C(C1=C(C(=C(C(=C1Br)Br)O)O)Br)C2=C(C(=C(C(=C2Br)Br)O)O)Br	IC50 ~ 50000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BON4B0	N,N-Dimethyl-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide	Investigative	135971717	C20H23N5O4S	429.5	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3C(=O)N(C)C)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BOS14J	3-[6-(4-Butylphenyl)pyridin-2-yl]-5-(1H-indol-3-ylmethyl)-1,2,4-oxadiazole	Investigative	127028685	C26H24N4O	408.5	CCCCC1=CC=C(C=C1)C2=NC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BP18XN	3-Benzoyl-1H-indole-5-carboxylic acid	Investigative	59762925	C16H11NO3	265.26	C1=CC=C(C=C1)C(=O)C2=CNC3=C2C=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BPG6R2	3-[(3-Acetyl-2-methyl-1-benzofuran-5-yl)sulfamoyl]benzoic acid	Investigative	1159989	C18H15NO6S	373.4	CC1=C(C2=C(O1)C=CC(=C2)NS(=O)(=O)C3=CC=CC(=C3)C(=O)O)C(=O)C	IC50 = 176000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BPH1J8	3-[2-(2-Nitrophenyl)hydrazinyl]indol-2-one	Investigative	3734796	C14H10N4O3	282.25	C1=CC=C2C(=C1)C(=C(N2)O)N=NC3=CC=CC=C3[N+](=O)[O-]	IC50 ~ 60000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BPO81M	6-Hydroxy-1-methyl-3-(1-(3-oxo-3-(phenylamino)propyl)-1H-1,2,3-triazol-4-yl)-2-phenyl-1H-indole-5-carboxylic acid	Investigative	45378929	C27H23N5O4	481.5	CN1C2=CC(=C(C=C2C(=C1C3=CC=CC=C3)C4=CN(N=N4)CCC(=O)NC5=CC=CC=C5)C(=O)O)O	IC50 = 86000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BPV5C1	6-[(3-Carboxyphenyl)carbamoyl]naphthalene-2-carboxylic acid	Investigative	59763033	C19H13NO5	335.3	C1=CC(=CC(=C1)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BQ4N6Z	3-[[5-(Diethylcarbamoyl)-2-hydroxy-1H-indol-3-yl]diazenyl]benzoic acid	Investigative	135971784	C20H20N4O4	380.4	CCN(CC)C(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC(=C3)C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BQA13G	N-[(4-Methoxyphenyl)methyl]-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide	Investigative	135971795	C22H19N5O6S	481.5	COC1=CC=C(C=C1)CNS(=O)(=O)C2=CC3=C(C=C2)NC(=C3N=NC4=CC=CC=C4[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BQF7L5	N-(Furan-2-ylmethyl)-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide	Investigative	135971758	C19H15N5O6S	441.4	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=CO4)O)[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BQJ3W6	2-Oxo-3-[2-[2-(trifluoromethyl)phenyl]hydrazinyl]indole-5-sulfonic acid	Investigative	135971723	C15H10F3N3O4S	385.3	C1=CC=C(C(=C1)C(F)(F)F)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)O)O	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BQLS05	US8987474, Rpm347	Investigative	59762903	C20H20N2O5S	400.4	CC(C)NS(=O)(=O)C1=CC\\2=C(C=C1)NC(=O)/C2=C\\C3=CC=CC=C3C(=O)OC	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BQW4B5	N-Butan-2-yl-3-[2-(2-nitrophenyl)hydrazinyl]-2-oxoindole-5-sulfonamide	Investigative	135971700	C18H19N5O5S	417.4	CCC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3[N+](=O)[O-])O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BR2VX4	2-[[5-[(4-Chlorophenyl)methylcarbamoyl]-2-hydroxy-1H-indol-3-yl]diazenyl]benzoic acid	Investigative	135971780	C23H17ClN4O4	448.9	C1=CC=C(C(=C1)C(=O)O)N=NC2=C(NC3=C2C=C(C=C3)C(=O)NCC4=CC=C(C=C4)Cl)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BR9WS3	US8987474, Rpm187	Investigative	59762981	C19H16N2O5S	384.4	COC(=O)C1=CC2=C(C=C1)C=C(C=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)N	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BRJ0D6	3-Benzoyl-1H-indole-5-carboxylic acid methyl ester	Investigative	59762957	C17H13NO3	279.29	COC(=O)C1=CC2=C(C=C1)NC=C2C(=O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BRJ0T9	US8987474, Rpm351	Investigative	59763022	C20H13NO3	315.3	C1=CC=C2C(=C1)C=CC=C2C(=O)C3=CNC4=C3C=C(C=C4)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BRS8W5	N-Benzyl-2-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide	Investigative	135971706	C25H25N5O4S	491.6	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3C(=O)NCC4=CC=CC=C4)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BS1X3B	US8987474, Rpm154	Investigative	135971725	C17H17N5O5S	403.4	CN1C2=C(C=C(C=C2)S(=O)(=O)N(C)C)C(=C1O)N=NC3=CC=CC=C3[N+](=O)[O-]	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BS2WM1	N-Butan-2-yl-3-[(2-chlorophenyl)diazenyl]-2-hydroxy-1H-indole-5-sulfonamide	Investigative	135971787	C18H19ClN4O3S	406.9	CCC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3Cl)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BS58AM	5-(1H-Indol-3-ylmethyl)-3-[6-(4-propoxyphenyl)pyridin-2-yl]-1,2,4-oxadiazole	Investigative	127024952	C25H22N4O2	410.5	CCCOC1=CC=C(C=C1)C2=NC(=CC=C2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BSX15N	3-[2-(2,6-Dichlorophenyl)hydrazinyl]-2-oxoindole-5-sulfonic acid	Investigative	135971753	C14H9Cl2N3O4S	386.2	C1=CC(=C(C(=C1)Cl)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)O)O)Cl	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BSX6P1	N-Methyl-3-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide	Investigative	135971737	C19H21N5O4S	415.5	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC(=C3)C(=O)NC)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BSX7M6	US8987474, Rpm194	Investigative	59762988	C19H13NO5	335.3	C1=CC(=CC=C1C(=O)O)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BT2V4A	Azane;[[4-[2-[[4-[difluoro(phosphono)methyl]phenyl]methoxy]ethoxymethyl]phenyl]-difluoromethyl]phosphonic acid	Investigative	49796692	C18H32F4N4O8P2	570.4	C1=CC(=CC=C1COCCOCC2=CC=C(C=C2)C(F)(F)P(=O)(O)O)C(F)(F)P(=O)(O)O.N.N.N.N	IC50 = 152000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BTM17F	2-Oxo-3-(2-phenylhydrazinyl)-N-propan-2-ylindole-5-sulfonamide	Investigative	135971701	C17H18N4O3S	358.4	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BTV6B9	N-Ethyl-3-[2-[2-oxo-5-(propan-2-ylsulfamoyl)indol-3-yl]hydrazinyl]benzamide	Investigative	135971775	C20H23N5O4S	429.5	CCNC(=O)C1=CC(=CC=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NC(C)C)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BTY64I	4-[5-[4-(2,3-Dichlorophenyl)piperazin-1-yl]sulfonyl-2,3-dihydroindol-1-yl]-4-oxobutanoic acid	Investigative	44624891	C22H23Cl2N3O5S	512.4	C1CN(C2=C1C=C(C=C2)S(=O)(=O)N3CCN(CC3)C4=C(C(=CC=C4)Cl)Cl)C(=O)CCC(=O)O	IC50 = 143600 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BU2BS9	(2S)-3-[[1-[[(2R,3R,4S,5S,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoic acid	Investigative	56670422	C39H48N4O10	732.8	CC(C)(C)OC(=O)N[C@@H](COCC1=CN(N=N1)C[C@@H]2[C@H]([C@@H]([C@@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5)C(=O)O	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BU65YL	N-(4-Butylphenyl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide	Investigative	1820399	C21H20N2O3S	380.5	CCCCC1=CC=C(C=C1)NS(=O)(=O)C2=C3C=CC=C4C3=C(C=C2)NC4=O	IC50 ~ 50000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BU73ND	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-propyl-1H-indole-5-sulfonamide	Investigative	135971708	C17H17ClN4O3S	392.9	CCCNS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3Cl)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BUB67R	(2Z,5E)-2-(1,2-Benzothiazol-3-ylimino)-5-[(4-hydroxy-3-methoxyphenyl)methylidene]-1,3-thiazolidin-4-one	Investigative	135924158	C18H13N3O3S2	383.4	COC1=C(C=CC(=C1)/C=C/2\\C(=O)NC(=NC3=NSC4=CC=CC=C43)S2)O	Ki = 90800 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BV6K2B	N-(2-Furylmethyl)-N'-{2-[4-(4-methoxyphenyl)piperazin-1-yl]-1-methyl-2-thien-2-ylethyl}ethanediamide	Investigative	20866499	C25H30N4O4S	482.6	CC(C(C1=CC=CS1)N2CCN(CC2)C3=CC=C(C=C3)OC)NC(=O)C(=O)NCC4=CC=CO4	IC50 ~ 50000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BVO69E	3-[2-(2-Nitrophenyl)hydrazinyl]-2-oxo-N-(pyridin-2-ylmethyl)indole-5-sulfonamide	Investigative	135971767	C20H16N6O5S	452.4	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)NCC4=CC=CC=N4)O)[N+](=O)[O-]	IC50 = 66500 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BW7VS3	4-[Acetyl(6,7,8,9-tetrahydrodibenzofuran-2-yl)sulfamoyl]benzoic acid	Investigative	2964738	C21H19NO6S	413.4	CC(=O)N(C1=CC2=C(C=C1)OC3=C2CCCC3)S(=O)(=O)C4=CC=C(C=C4)C(=O)O	IC50 = 181000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BWJ25U	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-1H-indole-5-sulfonamide	Investigative	135971711	C14H11ClN4O3S	350.8	C1=CC=C(C(=C1)N=NC2=C(NC3=C2C=C(C=C3)S(=O)(=O)N)O)Cl	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BWQ06J	5-(1H-Indol-3-ylmethyl)-3-[5-(2-methylphenyl)thiophen-2-yl]-1,2,4-oxadiazole	Investigative	127027725	C22H17N3OS	371.5	CC1=CC=CC=C1C2=CC=C(S2)C3=NOC(=N3)CC4=CNC5=CC=CC=C54	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BWTC98	3-[(2-Chlorophenyl)diazenyl]-2-hydroxy-N-(2-methoxyethyl)-1H-indole-5-sulfonamide	Investigative	135971716	C17H17ClN4O4S	408.9	COCCNS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3Cl)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BXMB23	2-[[2-Hydroxy-5-(propan-2-ylcarbamoyl)-1H-indol-3-yl]diazenyl]benzoic acid	Investigative	135971731	C19H18N4O4	366.4	CC(C)NC(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC=C3C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BXT2S9	(2S,3S)-3-[[1-[[(2R,3R,4S,5R,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid	Investigative	56673907	C40H50N4O10	746.8	C[C@@H]([C@@H](C(=O)O)NC(=O)OC(C)(C)C)OCC1=CN(N=N1)C[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BXU73H	3-[2-(2-Oxoindol-3-yl)hydrazinyl]benzoic Acid	Investigative	135647237	C15H11N3O3	281.27	C1=CC=C2C(=C1)C(=C(N2)O)N=NC3=CC=CC(=C3)C(=O)O	IC50 ~ 60000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BXYV59	US8987474, Rpm334	Investigative	135971695	C24H30N6O5S	514.6	CC(C)NS(=O)(=O)C1=CC2=C(C=C1)NC(=C2N=NC3=CC=CC(=C3)C(=O)NCCN4CCOCC4)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BY3N8X	Methyl (2S)-2-[4-(benzamidomethyl)triazol-1-yl]-3-(4-hydroxyphenyl)propanoate	Investigative	53319270	C20H20N4O4	380.4	COC(=O)[C@H](CC1=CC=C(C=C1)O)N2C=C(N=N2)CNC(=O)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BZ2D5F	3-[2-(2-Ethylphenyl)hydrazinyl]-2-oxoindole-5-carboxylic acid	Investigative	135971697	C17H15N3O3	309.32	CCC1=CC=CC=C1N=NC2=C(NC3=C2C=C(C=C3)C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BZ4K9S	US8987474, HL2-022-1-Intermediate	Investigative	59762892	C22H19NO5	377.4	CCOC(=O)C1=CC(=CC=C1)NC(=O)C2=CC3=C(C=C2)C=C(C=C3)C(=O)OC	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BZ6I2B	US8987474, Rpm350	Investigative	59762966	C21H15NO3	329.3	COC(=O)C1=CC2=C(C=C1)NC=C2C(=O)C3=CC=CC4=CC=CC=C43	IC50 ~ 100000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BZTU59	(2S,3S)-3-[[1-[[(2R,3R,4S,5S,6S)-6-Methoxy-3,4,5-tris(phenylmethoxy)oxan-2-yl]methyl]triazol-4-yl]methoxy]-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid	Investigative	56683883	C40H50N4O10	746.8	C[C@@H]([C@@H](C(=O)O)NC(=O)OC(C)(C)C)OCC1=CN(N=N1)C[C@@H]2[C@H]([C@@H]([C@@H]([C@H](O2)OC)OCC3=CC=CC=C3)OCC4=CC=CC=C4)OCC5=CC=CC=C5	IC50 ~ 120000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	BZY6H8	[(4-{2-[4-(Difluoro-phosphono-methyl)-benzyloxy]-phenoxymethyl}-phenyl)-difluoro-methyl]-phosphonic acid	Investigative	9985013	C22H20F4O8P2	550.3	C1=CC=C(C(=C1)OCC2=CC=C(C=C2)C(F)(F)P(=O)(O)O)OCC3=CC=C(C=C3)C(F)(F)P(=O)(O)O	IC50 = 60000 nM	Poor binder
T13057	Protein-tyrosine phosphatase SHP-2	D0SJ2Q	OLEANOLIC_ACID	Investigative	10494	C30H48O3	456.7	C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O	IC50 ~ 120000 nM	Poor binder