TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T13260	Aromatase	D02STN	ABIRATERONE	Approved	132971	C24H31NO	349.5	C[C@]12CC[C@@H](CC1=CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C5=CN=CC=C5)C)O	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	D0B4IF	Ketoconazole	Approved	3823	C26H28Cl2N4O4	531.4	CC(=O)N1CCN(CC1)C2=CC=C(C=C2)OCC3COC(O3)(CN4C=CN=C4)C5=C(C=C(C=C5)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	D0L4FS	Genistein	Phase 2	5280961	C15H10O5	270.24	C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O	Ki = 100000 nM	Poor binder
T13260	Aromatase	D03YPJ	SB 206553	Terminated	5163	C17H16N4O	292.33	CN1C=CC2=CC3=C(CCN3C(=O)NC4=CN=CC=C4)C=C21	IC50 ~ 100000 nM	Poor binder
T13260	Aromatase	B0BW5R	3-(3-Methoxyphenyl)-2,3-dihydrochromen-4-one	Investigative	59356085	C16H14O3	254.28	COC1=CC=CC(=C1)C2COC3=CC=CC=C3C2=O	IC50 = 99000 nM	Poor binder
T13260	Aromatase	B0GEC5	3,5-Bis(4-methoxyphenyl)-1,2,4-thiadiazole	Investigative	596715	C16H14N2O2S	298.4	COC1=CC=C(C=C1)C2=NSC(=N2)C3=CC=C(C=C3)OC	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B0TNC4	3-[5-(3-Cyanophenyl)-1,2,4-thiadiazol-3-yl]benzonitrile	Investigative	57402418	C16H8N4S	288.3	C1=CC(=CC(=C1)C2=NSC(=N2)C3=CC=CC(=C3)C#N)C#N	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B15VAL	3,5-Bis[2-(trifluoromethyl)phenyl]-1,2,4-thiadiazole	Investigative	57390180	C16H8F6N2S	374.3	C1=CC=C(C(=C1)C2=NSC(=N2)C3=CC=CC=C3C(F)(F)F)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B1DS7L	(5S,10S,13S)-10,13-Dimethyl-17-pyridin-3-yl-1,2,4,5,6,7,8,9,10,11,12,13,14,15-tetradecahydro-cyclopenta[a]phenanthren-3-one	Investigative	44461241	C24H31NO	349.5	C[C@]12CCC(=O)C[C@@H]1CCC3C2CC[C@]4(C3CC=C4C5=CN=CC=C5)C	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B1QB3H	3,5-Bis(3-chloro-2-methylphenyl)-1,2,4-thiadiazole	Investigative	57398928	C16H12Cl2N2S	335.2	CC1=C(C=CC=C1Cl)C2=NSC(=N2)C3=C(C(=CC=C3)Cl)C	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B1UK8E	Methyl (3S)-2-[(4-hydroxyphenyl)methyl]-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylate	Investigative	57400842	C20H20N2O3	336.4	COC(=O)[C@@H]1CC2=C(CN1CC3=CC=C(C=C3)O)NC4=CC=CC=C24	IC50 = 57400 nM	Poor binder
T13260	Aromatase	B20DYF	10-(1-Hydroxy-prop-2-ynyl)-13-methyl-1,2,3,6,7,8,9,10,11,12,13,14,15,16-tetradecahydro-cyclopenta[a]phenanthren-17-one	Investigative	14860811	C21H28O2	312.4	CC12CCC3C(C1CCC2=O)CCC4=CCCCC34C(C#C)O	IC50 = 62000 nM	Poor binder
T13260	Aromatase	B29IUW	3-(1a,2,3,7b-Tetrahydro-1H-cyclopropa[a]naphthalen-1-yl)-1H-pyrazole	Investigative	10727176	C14H14N2	210.27	C1CC2=CC=CC=C2C3C1C3C4=CC=NN4	IC50 = 51000 nM	Poor binder
T13260	Aromatase	B2D6QU	3,5-Bis(2-fluorophenyl)-1,2,4-thiadiazole	Investigative	56837845	C14H8F2N2S	274.29	C1=CC=C(C(=C1)C2=NSC(=N2)C3=CC=CC=C3F)F	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B2E3YQ	10-Hydroxymethyl-13-methyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol	Investigative	44310412	C19H30O2	290.4	CC12CCC3C(C1CCC2O)CC=C4C3(CCCC4)CO	IC50 = 62000 nM	Poor binder
T13260	Aromatase	B2G5WA	2-(4-Phenoxyphenyl)-2,3-dihydrobenzo[f]chromen-1-one	Investigative	73055877	C25H18O3	366.4	C1C(C(=O)C2=C(O1)C=CC3=CC=CC=C32)C4=CC=C(C=C4)OC5=CC=CC=C5	IC50 = 190000 nM	Poor binder
T13260	Aromatase	B2XN5M	7-Methoxy-3-phenyl-2-(pyridin-2-ylmethylsulfanyl)chromen-4-one	Investigative	11485667	C22H17NO3S	375.4	COC1=CC2=C(C=C1)C(=O)C(=C(O2)SCC3=CC=CC=N3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T13260	Aromatase	B37OUH	Bis(4-fluorophenyl)-1,2,4-thiadiazole	Investigative	46834487	C14H8F2N2S	274.29	C1=CC(=CC=C1C2=NSC(=N2)C3=CC=C(C=C3)F)F	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B3I6WN	Acetic acid 10-hydroxymethyl-13-methyl-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl ester	Investigative	14860791	C21H32O3	332.5	CC(=O)OC1CCC2C1(CCC3C2CCC4=CCCCC34CO)C	IC50 = 100000 nM	Poor binder
T13260	Aromatase	B3ODR4	(R)-16-Bromo-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-cyclopenta[a]phenanthren-17-one	Investigative	44310768	C19H27BrO	351.3	CC12CCCCC1=CCC3C2CCC4(C3C[C@H](C4=O)Br)C	IC50 = 55000 nM	Poor binder
T13260	Aromatase	B47VCS	3,5-Bis(4-nitrophenyl)-1,2,4-thiadiazole	Investigative	11381850	C14H8N4O4S	328.3	C1=CC(=CC=C1C2=NSC(=N2)C3=CC=C(C=C3)[N+](=O)[O-])[N+](=O)[O-]	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B4HRI3	10-Hydroxymethyl-13-methyl-1,3,4,8,9,10,11,12,13,14,15,16-dodecahydro-2H-cyclopenta[a]phenanthrene-7,17-dione	Investigative	44310410	C19H26O3	302.4	CC12CCC3C(C1CCC2=O)C(=O)C=C4C3(CCCC4)CO	IC50 = 56000 nM	Poor binder
T13260	Aromatase	B4LTU8	Methyl (3S)-2-(4-methylphenyl)sulfonyl-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylate	Investigative	57392056	C20H20N2O4S	384.5	CC1=CC=C(C=C1)S(=O)(=O)N2CC3=C(C[C@H]2C(=O)OC)C4=CC=CC=C4N3	IC50 = 63200 nM	Poor binder
T13260	Aromatase	B4Q3IV	3,5-Bis(2-bromo-4-methylphenyl)-1,2,4-thiadiazole	Investigative	57395400	C16H12Br2N2S	424.2	CC1=CC(=C(C=C1)C2=NSC(=N2)C3=C(C=C(C=C3)C)Br)Br	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B4YR9N	2,6-Piperidinedione, 3-ethyl-3-(4-pyridinyl)-, (R)-	Investigative	9794431	C12H14N2O2	218.25	CC[C@@]1(CCC(=O)NC1=O)C2=CC=NC=C2	IC50 = 63000 nM	Poor binder
T13260	Aromatase	B5C2ZE	7-(Benzyloxy)-2-(benzylsulfanyl)-3-(4-methoxyphenyl)-4H-chromen-4-one	Investigative	11213800	C30H24O4S	480.6	COC1=CC=C(C=C1)C2=C(OC3=C(C2=O)C=CC(=C3)OCC4=CC=CC=C4)SCC5=CC=CC=C5	IC50 ~ 100000 nM	Poor binder
T13260	Aromatase	B5CXO1	2-(3-Methoxyphenyl)-4-phenyl-1,3-thiazole	Investigative	8963350	C16H13NOS	267.3	COC1=CC=CC(=C1)C2=NC(=CS2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B5FX7N	3,5-Bis(2-naphthyl)-1,2,4-thiadiazole	Investigative	13437151	C22H14N2S	338.4	C1=CC=C2C=C(C=CC2=C1)C3=NSC(=N3)C4=CC5=CC=CC=C5C=C4	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B5OY7I	3-Hydroxy-1-(2-hydroxy-4-methoxyphenyl)-3-[4-methoxy-3-(3-methylbut-2-enyl)phenyl]propan-1-one	Investigative	16738210	C22H26O5	370.4	CC(=CCC1=C(C=CC(=C1)C(CC(=O)C2=C(C=C(C=C2)OC)O)O)OC)C	IC50 = 54670 nM	Poor binder
T13260	Aromatase	B5Q6KW	Methyl (3S)-2-(cyclopropylmethyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylate	Investigative	57397346	C17H20N2O2	284.35	COC(=O)[C@@H]1CC2=C(CN1CC3CC3)NC4=CC=CC=C24	IC50 = 58600 nM	Poor binder
T13260	Aromatase	B5QB6R	3,5-Bis(4-methylphenyl)-1,2,4-thiadiazole	Investigative	5121919	C16H14N2S	266.4	CC1=CC=C(C=C1)C2=NSC(=N2)C3=CC=C(C=C3)C	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B5X9IM	4'-Hydroxyisoflavanone	Investigative	69198620	C15H12O3	240.25	C1C(C(=O)C2=CC=CC=C2O1)C3=CC=C(C=C3)O	IC50 = 160000 nM	Poor binder
T13260	Aromatase	B5ZO9M	Abyssinone II	Investigative	10064832	C20H20O4	324.4	CC(=CCC1=C(C=CC(=C1)C2CC(=O)C3=C(O2)C=C(C=C3)O)O)C	IC50 = 62000 nM	Poor binder
T13260	Aromatase	B6ECX1	Methyl (3R)-2-methylsulfonyl-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylate	Investigative	57397345	C14H16N2O4S	308.35	COC(=O)[C@H]1CC2=C(CN1S(=O)(=O)C)NC3=CC=CC=C23	IC50 = 68100 nM	Poor binder
T13260	Aromatase	B6Q8CM	2-Hydroxyisoflavanone	Investigative	13257279	C15H12O3	240.25	C1=CC=C(C=C1)C2C(OC3=CC=CC=C3C2=O)O	IC50 = 170000 nM	Poor binder
T13260	Aromatase	B6SV4O	3,5-Bis(4-chloro-2-methylphenyl)-1,2,4-thiadiazole	Investigative	57390179	C16H12Cl2N2S	335.2	CC1=C(C=CC(=C1)Cl)C2=NSC(=N2)C3=C(C=C(C=C3)Cl)C	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B74YFX	7-Methoxy-3-phenyl-2-(1H-1,2,4-triazol-3-ylsulfanyl)-4H-chromen-4-one	Investigative	23644938	C18H13N3O3S	351.4	COC1=CC2=C(C=C1)C(=O)C(=C(O2)SC3=NC=NN3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B79EYC	(3S)-2-(2-Methylpropyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylic acid	Investigative	57397347	C16H20N2O2	272.34	CC(C)CN1CC2=C(C[C@H]1C(=O)O)C3=CC=CC=C3N2	IC50 = 72000 nM	Poor binder
T13260	Aromatase	B85CUJ	2H-1-Benzopyran-2-one, 4-[2-(1H-imidazol-1-yl)ethoxy]-7-methoxy-	Investigative	11243132	C15H14N2O4	286.28	COC1=CC2=C(C=C1)C(=CC(=O)O2)OCCN3C=CN=C3	IC50 = 100000 nM	Poor binder
T13260	Aromatase	B8EVU6	(Z)-Resveratrol	Investigative	1548910	C14H12O3	228.24	C1=CC(=CC=C1/C=C\\C2=CC(=CC(=C2)O)O)O	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B8O0QD	2,4b-Dimethyl-7-oxo-1,2,3,4,4a,4b,7,9,10,10a-decahydro-phenanthrene-2-carboxylic acid methyl ester	Investigative	14442760	C18H24O3	288.4	CC1(CCC2C(C1)CCC3=CC(=O)C=CC23C)C(=O)OC	Ki = 130000 nM	Poor binder
T13260	Aromatase	B8PUX3	4-Methylquinolin-2-ol	Investigative	69088	C10H9NO	159.18	CC1=CC(=O)NC2=CC=CC=C12	IC50 ~ 125700 nM	Poor binder
T13260	Aromatase	B8T6UA	3,5-Bis(3-fluorophenyl)-1,2,4-thiadiazole	Investigative	57393684	C14H8F2N2S	274.29	C1=CC(=CC(=C1)F)C2=NSC(=N2)C3=CC(=CC=C3)F	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B8VH6L	4,4'-(1,2,4-Thiadiazole-3,5-diyl)bisphenol	Investigative	135926058	C14H10N2O2S	270.31	C1=CC(=CC=C1C2=NSC(=N2)C3=CC=C(C=C3)O)O	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B97CUM	Bis(4-tert-butylphenyl)-1,2,4-thiadiazole	Investigative	57393682	C22H26N2S	350.5	CC(C)(C)C1=CC=C(C=C1)C2=NSC(=N2)C3=CC=C(C=C3)C(C)(C)C	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	B9JC4O	10-Hydroxymethyl-13-methyl-1,8,9,10,11,12,13,14,15,16-decahydro-2H-cyclopenta[a]phenanthrene-7,17-dione	Investigative	44310046	C19H24O3	300.4	CC12CCC3C(C1CCC2=O)C(=O)C=C4C3(CCC=C4)CO	IC50 = 60000 nM	Poor binder
T13260	Aromatase	B9PFJ4	2-Methyl-2-pyridin-3-yl-propionic acid (3R,6R)-3,6,8,8-tetramethyl-octahydro-3a,7-methano-azulen-6-yl ester	Investigative	44354944	C24H35NO2	369.5	C[C@@H]1CCC2C13CC[C@@](C(C3)C2(C)C)(C)OC(=O)C(C)(C)C4=CN=CC=C4	IC50 = 80500 nM	Poor binder
T13260	Aromatase	B9TZ5X	Eicosapentaenoic acid	Investigative	446284	C20H30O2	302.5	CC/C=C\\C/C=C\\C/C=C\\C/C=C\\C/C=C\\CCCC(=O)O	IC50 = 53200 nM	Poor binder
T13260	Aromatase	B9ZS1A	1,2,4-Thiadiazole, 3,5-bis(4-chlorophenyl)-	Investigative	199390	C14H8Cl2N2S	307.2	C1=CC(=CC=C1C2=NSC(=N2)C3=CC=C(C=C3)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BB7VO3	3,5-Bis(3,4-dichlorophenyl)-1,2,4-thiadiazole	Investigative	57398927	C14H6Cl4N2S	376.1	C1=CC(=C(C=C1C2=NSC(=N2)C3=CC(=C(C=C3)Cl)Cl)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BBSI14	3,5-Bis(2-bromophenyl)-1,2,4-thiadiazole	Investigative	56837844	C14H8Br2N2S	396.1	C1=CC=C(C(=C1)C2=NSC(=N2)C3=CC=CC=C3Br)Br	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BC8I1H	4a,7-Dimethyl-7-propionyl-4b,5,6,7,8,8a,9,10-octahydro-4aH-phenanthren-2-one	Investigative	14442772	C19H26O2	286.4	CCC(=O)C1(CCC2C(C1)CCC3=CC(=O)C=CC23C)C	Ki = 97000 nM	Poor binder
T13260	Aromatase	BC9ZB0	3,4-Dihydro-2-[(E)-(pyridazin-4-yl)methylene]naphthalen-1(2H)-one	Investigative	10752290	C15H12N2O	236.27	C1C/C(=C\\C2=CN=NC=C2)/C(=O)C3=CC=CC=C31	IC50 = 103000 nM	Poor binder
T13260	Aromatase	BCM7L8	8-Methoxy-4-methylquinolin-2(1H)-one	Investigative	782123	C11H11NO2	189.21	CC1=CC(=O)NC2=C1C=CC=C2OC	IC50 ~ 105800 nM	Poor binder
T13260	Aromatase	BCPL84	3,5-Bis(2-chlorophenyl)-1,2,4-thiadiazole	Investigative	198531	C14H8Cl2N2S	307.2	C1=CC=C(C(=C1)C2=NSC(=N2)C3=CC=CC=C3Cl)Cl	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BD4GI3	1,4-Dimethylquinoline-2,5,8(1H)-trione	Investigative	14929519	C11H9NO3	203.19	CC1=CC(=O)N(C2=C1C(=O)C=CC2=O)C	IC50 ~ 98400 nM	Poor binder
T13260	Aromatase	BDKC05	3,5-Bis[4-(trifluoromethyl)phenyl]-1,2,4-thiadiazole	Investigative	57393681	C16H8F6N2S	374.3	C1=CC(=CC=C1C2=NSC(=N2)C3=CC=C(C=C3)C(F)(F)F)C(F)(F)F	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BE4MJ7	7-Methoxy-2-[(1-methyl-1H-imidazol-2-yl)sulfanyl]-3-phenyl-4H-chromen-4-one	Investigative	23644937	C20H16N2O3S	364.4	CN1C=CN=C1SC2=C(C(=O)C3=C(O2)C=C(C=C3)OC)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BE4U7C	Bis(3-methylphenyl)-1,2,4-thiadiazole	Investigative	12846880	C16H14N2S	266.4	CC1=CC(=CC=C1)C2=NSC(=N2)C3=CC=CC(=C3)C	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BG2C6J	4-[(4-Cyanophenyl)-(triazol-2-yl)methyl]benzonitrile	Investigative	54771121	C17H11N5	285.3	C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3N=CC=N3	IC50 = 79980 nM	Poor binder
T13260	Aromatase	BG37MD	3,5-Diphenyl-1,2,4-thiadiazole	Investigative	165184	C14H10N2S	238.31	C1=CC=C(C=C1)C2=NSC(=N2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BG7Q6I	6-Tert-butyl-3-phenyl-2,3-dihydrochromen-4-one	Investigative	70683101	C19H20O2	280.4	CC(C)(C)C1=CC2=C(C=C1)OCC(C2=O)C3=CC=CC=C3	IC50 = 61000 nM	Poor binder
T13260	Aromatase	BHA64M	CID 71621803	Investigative	71621803	C31H20F4N6O2	584.5	C1=CC(=CC=C1COC2=CC=C(C=C2)C#CC3=CN=C(C=C3)C(C(CN4C=NN=N4)(C5=C(C=C(C=C5)F)F)O)(F)F)C#N	IC50 ~ 100000 nM	Poor binder
T13260	Aromatase	BHT9C6	4beta-Methoxy-19-hydroxyandrosta-5-ene-17-one	Investigative	11758964	C20H30O3	318.4	C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CC=C4[C@@]3(CCC[C@@H]4OC)CO	IC50 = 150000 nM	Poor binder
T13260	Aromatase	BI37FZ	3,5-Bis(4-butylphenyl)-1,2,4-thiadiazole	Investigative	57398929	C22H26N2S	350.5	CCCCC1=CC=C(C=C1)C2=NSC(=N2)C3=CC=C(C=C3)CCCC	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BI67LQ	3,5-Bis(2,4-dichlorophenyl)-1,2,4-thiadiazole	Investigative	51351108	C14H6Cl4N2S	376.1	C1=CC(=C(C=C1Cl)Cl)C2=NSC(=N2)C3=C(C=C(C=C3)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BIK29M	2,4-Bis(3-Methoxyphenyl)Thiazole	Investigative	24431784	C17H15NO2S	297.4	COC1=CC=CC(=C1)C2=CSC(=N2)C3=CC(=CC=C3)OC	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BJF50K	19-Ethynyl-19-acetoxyandrost-4-ene-3,6,17-trione	Investigative	10317756	C23H26O5	382.4	CC(=O)O[C@@H](C#C)[C@]12CCC(=O)C=C1C(=O)C[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C	Ki = 67000 nM	Poor binder
T13260	Aromatase	BK51HX	4-Methyl-2-oxo-2H-chromene-5,7-diyl-dibutyrate	Investigative	390805	C18H20O6	332.3	CCCC(=O)OC1=CC2=C(C(=CC(=O)O2)C)C(=C1)OC(=O)CCC	IC50 = 176000 nM	Poor binder
T13260	Aromatase	BKQA31	(1R,2S,5S,6S,9S,10R,16S)-1,5-Dimethyl-14-oxa-13-azapentacyclo[10.6.1.02,10.05,9.015,19]nonadeca-12,15(19)-diene-6,16-diol	Investigative	127026653	C19H27NO3	317.4	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CC4=NOC5=C4[C@@]3(CC[C@@H]5O)C	IC50 = 120500 nM	Poor binder
T13260	Aromatase	BM0R5I	3,5-Bis(2-iodophenyl)-1,2,4-thiadiazole	Investigative	54756790	C14H8I2N2S	490.1	C1=CC=C(C(=C1)C2=NSC(=N2)C3=CC=CC=C3I)I	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BMT3U4	(20S)-21-Aziridinylpregn-5-en-3beta-ol	Investigative	71454429	C21H33NO	315.5	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2[C@H]4CN4)CC=C5[C@@]3(CC[C@@H](C5)O)C	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BN1J8E	1,2,4b-Trimethyl-7-oxo-1,2,3,4,4a,4b,7,9,10,10a-decahydro-phenanthrene-2-carboxylic acid methyl ester	Investigative	14442756	C19H26O3	302.4	CC1C2CCC3=CC(=O)C=CC3(C2CCC1(C)C(=O)OC)C	Ki = 103000 nM	Poor binder
T13260	Aromatase	BN25FX	17-Hydroxy-10-hydroxymethyl-13-methyl-1,2,3,4,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-7-one	Investigative	44310411	C19H28O3	304.4	CC12CCC3C(C1CCC2O)C(=O)C=C4C3(CCCC4)CO	IC50 = 140000 nM	Poor binder
T13260	Aromatase	BN69ZL	Methyl (3S)-2-(2-methylpropyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxylate	Investigative	57390275	C17H22N2O2	286.37	CC(C)CN1CC2=C(C[C@H]1C(=O)OC)C3=CC=CC=C3N2	IC50 = 64500 nM	Poor binder
T13260	Aromatase	BN7ZH3	(4-Pyridylmethylene)tetrahydronaphthalene 18a	Investigative	6539802	C18H19NO2	281.3	COC1=C(C=C\\2C(=C1)CCC/C2=C\\C3=CC=NC=C3)OC	IC50 = 89949.76 nM	Poor binder
T13260	Aromatase	BNY02Q	3,5-Bis(3-bromophenyl)-1,2,4-thiadiazole	Investigative	11784241	C14H8Br2N2S	396.1	C1=CC(=CC(=C1)Br)C2=NSC(=N2)C3=CC(=CC=C3)Br	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BP03HR	4-(3-Methoxyphenyl)-2-phenyl-1,3-thiazole	Investigative	18731901	C16H13NOS	267.3	COC1=CC=CC(=C1)C2=CSC(=N2)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BP7NW5	2-(Allylthio)-3-phenyl-7-methoxy-4H-1-benzopyran-4-one	Investigative	11244229	C19H16O3S	324.4	COC1=CC2=C(C=C1)C(=O)C(=C(O2)SCC=C)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T13260	Aromatase	BPQ79R	2,6-Piperidinedione, 3-(4-aminophenyl)-3-methyl-	Investigative	13660215	C12H14N2O2	218.25	CC1(CCC(=O)NC1=O)C2=CC=C(C=C2)N	IC50 = 135000 nM	Poor binder
T13260	Aromatase	BQG3J6	3,5-Bis(3-iodophenyl)-1,2,4-thiadiazole	Investigative	57400626	C14H8I2N2S	490.1	C1=CC(=CC(=C1)I)C2=NSC(=N2)C3=CC(=CC=C3)I	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BQL4A0	3,5-Bis(3-methoxyphenyl)-1,2,4-thiadiazole	Investigative	56837846	C16H14N2O2S	298.4	COC1=CC=CC(=C1)C2=NSC(=N2)C3=CC(=CC=C3)OC	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BQT1J7	8-Fluoro-3-(pyridin-3-yl)chroman-4-one	Investigative	73055880	C14H10FNO2	243.23	C1C(C(=O)C2=C(O1)C(=CC=C2)F)C3=CN=CC=C3	IC50 = 67100 nM	Poor binder
T13260	Aromatase	BQZ03X	3,5-Bis(5-chloro-2-methylphenyl)-1,2,4-thiadiazole	Investigative	57397238	C16H12Cl2N2S	335.2	CC1=C(C=C(C=C1)Cl)C2=NSC(=N2)C3=C(C=CC(=C3)Cl)C	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BR48KV	2-Ethyl-2-pyridin-4-yl-butyric acid (S)-2,6,6-trimethyl-bicyclo[3.1.1]hept-3-yl ester	Investigative	44354942	C21H31NO2	329.5	CCC(CC)(C1=CC=NC=C1)C(=O)OC2CC3CC([C@@H]2C)C3(C)C	IC50 = 55000 nM	Poor binder
T13260	Aromatase	BRC9A4	4,4'-(1,2,4-Thiadiazole-3,5-diyl)bisbenzonitrile	Investigative	57398930	C16H8N4S	288.3	C1=CC(=CC=C1C#N)C2=NSC(=N2)C3=CC=C(C=C3)C#N	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BSAJ69	3,5-Bis(4-bromo-2-methylphenyl)-1,2,4-thiadiazole	Investigative	57390181	C16H12Br2N2S	424.2	CC1=C(C=CC(=C1)Br)C2=NSC(=N2)C3=C(C=C(C=C3)Br)C	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BSR63T	(3R)-3alpha-Ethyl-5beta-methyl-3-(4-pyridinyl)piperidine-2,6-dione	Investigative	10082665	C13H16N2O2	232.28	CC[C@@]1(C[C@H](C(=O)NC1=O)C)C2=CC=NC=C2	IC50 = 93000 nM	Poor binder
T13260	Aromatase	BTN84I	2-Pyridin-3-ylpropan-2-yl Adamantane-1-carboxylate	Investigative	10566080	C19H25NO2	299.4	CC(C)(C1=CN=CC=C1)OC(=O)C23CC4CC(C2)CC(C4)C3	IC50 = 51000 nM	Poor binder
T13260	Aromatase	BU7J8M	3-(4-Methoxyphenyl)-7-(phenylmethoxy)-2-[(propen-3-yl)thio]-4H-1-benzopyran-4-one	Investigative	11774754	C26H22O4S	430.5	COC1=CC=C(C=C1)C2=C(OC3=C(C2=O)C=CC(=C3)OCC4=CC=CC=C4)SCC=C	IC50 ~ 100000 nM	Poor binder
T13260	Aromatase	BUHS39	Imidazolin-2-one, 11a	Investigative	16732000	C16H18ClN3O2	319.78	CC[C@H]1[C@@H]2[C@H](CCN2C(=O)N1C3=C(C(=C(C=C3)C#N)Cl)C)O	IC50 ~ 100000 nM	Poor binder
T13260	Aromatase	BUJ84H	2-(Benzylsulfanyl)-7-methoxy-3-phenyl-4H-chromen-4-one	Investigative	12137521	C23H18O3S	374.5	COC1=CC2=C(C=C1)C(=O)C(=C(O2)SCC3=CC=CC=C3)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T13260	Aromatase	BUZC38	3,5-Bis(2,5-dichlorophenyl)-1,2,4-thiadiazole	Investigative	57400627	C14H6Cl4N2S	376.1	C1=CC(=C(C=C1Cl)C2=NSC(=N2)C3=C(C=CC(=C3)Cl)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BW40XV	2'-Methoxyisoflavanone	Investigative	45378299	C16H14O3	254.28	COC1=CC=CC=C1C2COC3=CC=CC=C3C2=O	IC50 = 97000 nM	Poor binder
T13260	Aromatase	BXDC04	9-Hydroxy-7,8-dimethyl-7-[2-(5-oxo-2H-furan-3-yl)ethyl]-5,6,6a,8,9,10-hexahydro-1H-benzo[d][2]benzofuran-3-one	Investigative	343584	C20H26O5	346.4	CC1C(CC23COC(=O)C2=CCCC3C1(C)CCC4=CC(=O)OC4)O	IC50 = 126000 nM	Poor binder
T13260	Aromatase	BXJH46	Quinoline, 5,6,7,8-tetrahydro-8-(1H-imidazol-1-yl)-	Investigative	10774377	C12H13N3	199.25	C1CC(C2=C(C1)C=CC=N2)N3C=CN=C3	IC50 = 111000 nM	Poor binder
T13260	Aromatase	BYC8Z5	13-Methyl-7,17-dioxo-1,2,3,4,7,8,9,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthrene-10-carbaldehyde	Investigative	44310077	C19H24O3	300.4	CC12CCC3C(C1CCC2=O)C(=O)C=C4C3(CCCC4)C=O	IC50 = 60000 nM	Poor binder
T13260	Aromatase	BYO20P	[(1R)-1-[(8R,9S,10R,13S,14S)-13-Methyl-3,6,17-trioxo-1,2,7,8,9,11,12,14,15,16-decahydrocyclopenta[a]phenanthren-10-yl]prop-2-ynyl] acetate	Investigative	127036045	C23H26O5	382.4	CC(=O)O[C@H](C#C)[C@@]12CCC(=O)C=C1C(=O)C[C@@H]3[C@@H]2CC[C@]4([C@H]3CCC4=O)C	Ki = 75000 nM	Poor binder
T13260	Aromatase	BZ3U0O	1-[(2,4-Dichloro-phenyl)-(2,3-dihydro-benzofuran-2-yl)-methyl]-1H-tetrazole	Investigative	44306491	C16H12Cl2N4O	347.2	C1C(OC2=CC=CC=C21)C(C3=C(C=C(C=C3)Cl)Cl)N4C=NN=N4	IC50 = 52020 nM	Poor binder
T13260	Aromatase	BZ6E0X	2-(1H-Imidazol-2-ylsulfanyl)-7-methoxy-3-phenyl-4H-chromen-4-one	Investigative	23644936	C19H14N2O3S	350.4	COC1=CC2=C(C=C1)C(=O)C(=C(O2)SC3=NC=CN3)C4=CC=CC=C4	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BZ96NB	1-(2,4-Dihydroxyphenyl)-3-[4-methoxy-3-(3-methylbut-2-enyl)-phenyl]prop-2-en-1-one	Investigative	16738212	C21H22O4	338.4	CC(=CCC1=C(C=CC(=C1)/C=C/C(=O)C2=C(C=C(C=C2)O)O)OC)C	IC50 = 82940 nM	Poor binder
T13260	Aromatase	BZ9HY1	Bis(4-bromophenyl)-1,2,4-thiadiazole	Investigative	15485639	C14H8Br2N2S	396.1	C1=CC(=CC=C1C2=NSC(=N2)C3=CC=C(C=C3)Br)Br	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BZJ8V6	3,5-Bis(4-iodophenyl)-1,2,4-thiadiazole	Investigative	57393683	C14H8I2N2S	490.1	C1=CC(=CC=C1C2=NSC(=N2)C3=CC=C(C=C3)I)I	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	BZN3U6	3,5-Bis(2,3-dichlorophenyl)-1,2,4-thiadiazole	Investigative	57391954	C14H6Cl4N2S	376.1	C1=CC(=C(C(=C1)Cl)Cl)C2=NSC(=N2)C3=C(C(=CC=C3)Cl)Cl	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	D00EMF	SB 242084	Investigative	3644637	C21H19ClN4O2	394.9	CC1=CC2=C(C=C1Cl)N(CC2)C(=O)NC3=CN=C(C=C3)OC4=C(N=CC=C4)C	IC50 ~ 100000 nM	Poor binder
T13260	Aromatase	D00TWK	5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol	Investigative	185914	C14H14O3	230.26	C1=CC(=CC=C1CCC2=CC(=CC(=C2)O)O)O	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	D04LWL	1,4-Dimethylquinolin-2(1H)-one	Investigative	97252	C11H11NO	173.21	CC1=CC(=O)N(C2=CC=CC=C12)C	IC50 ~ 115600 nM	Poor binder
T13260	Aromatase	D08ISK	6,8-Dimethoxy-4-methylquinolin-2(1H)-one	Investigative	42618030	C12H13NO3	219.24	CC1=CC(=O)NC2=C1C=C(C=C2OC)OC	IC50 ~ 91290 nM	Poor binder
T13260	Aromatase	D0A0JL	RG-50810	Investigative	2052	C10H6N2O2	186.17	C1=CC(=C(C=C1C=C(C#N)C#N)O)O	IC50 = 70600 nM	Poor binder
T13260	Aromatase	D0A4XA	3,3'-(1,2,4-thiadiazole-3,5-diyl)diphenol	Investigative	25093379	C14H10N2O2S	270.31	C1=CC(=CC(=C1)O)C2=NSC(=N2)C3=CC(=CC=C3)O	IC50 ~ 50000 nM	Poor binder
T13260	Aromatase	D0DY5G	SB 221284	Investigative	443389	C16H14F3N3OS	353.4	CSC1=C(C=C2C(=C1)CCN2C(=O)NC3=CN=CC=C3)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T13260	Aromatase	D0O4YS	6-Methyl-[1,3]dioxolo[4,5-h]quinolin-8(9H)-one	Investigative	42618026	C11H9NO3	203.19	CC1=CC(=O)NC2=C1C=CC3=C2OCO3	IC50 ~ 98490 nM	Poor binder
T13260	Aromatase	D0SY2M	daidzein	Investigative	5281708	C15H10O4	254.24	C1=CC(=CC=C1C2=COC3=C(C2=O)C=CC(=C3)O)O	Ki = 100000 nM	Poor binder
T13260	Aromatase	D0Y7HG	GALANGIN	Investigative	5281616	C15H10O5	270.24	C1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O	Ki = 100000 nM	Poor binder