TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T15053	Lactate dehydrogenase A	B01BRA	3,8,9,10-Tetrahydroxy-5H-benzo[h]chromene-2,6-dione	Investigative	127041973	C13H8O7	276.2	C1C2=C(C3=C(C(=C(C=C3C1=O)O)O)O)OC(=O)C(=C2)O	Ki = 56000 nM	Poor binder
T15053	Lactate dehydrogenase A	B07FLC	2-[4-(4-Chlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrile	Investigative	118708937	C19H14ClNO2S	355.8	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2C#N)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B09PMX	3-[5-Amino-3-methyl-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]benzoic acid	Investigative	73353843	C20H20N4O2	348.4	CC1=C(N=C(C(=N1)N)N[C@H](C)C2=CC=CC=C2)C3=CC(=CC=C3)C(=O)O	IC50 = 91000 nM	Poor binder
T15053	Lactate dehydrogenase A	B0AGZ4	5-(2-Chlorophenyl)sulfanyl-4-hydroxy-2-pyrimidin-5-yl-2,3-dihydropyran-6-one	Investigative	118723154	C15H11ClN2O3S	334.8	C1C(OC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=CN=CN=C3	IC50 = 73000 nM	Poor binder
T15053	Lactate dehydrogenase A	B0C9WZ	2-(3-Chloro-2-fluorophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708913	C18H14ClFO2S	348.8	C1C(CC(=O)C(=C1O)SC2=C(C(=CC=C2)Cl)F)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B0J6GM	2-(2-Chlorophenyl)sulfanyl-5-(2,6-dimethylphenyl)-3-hydroxycyclohex-2-en-1-one	Investigative	118708932	C20H19ClO2S	358.9	CC1=C(C(=CC=C1)C)C2CC(=C(C(=O)C2)SC3=CC=CC=C3Cl)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B0S2NJ	3-[5-Amino-6-[[(1S)-1-phenylethyl]amino]pyrazin-2-yl]benzoic acid	Investigative	72190457	C19H18N4O2	334.4	C[C@@H](C1=CC=CC=C1)NC2=NC(=CN=C2N)C3=CC(=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B0Z2NF	3-Hydroxy-5-phenyl-2-phenylsulfanylcyclohex-2-en-1-one	Investigative	2729667	C18H16O2S	296.4	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B1BM9Z	3-Hydroxy-2-(4-hydroxyphenyl)sulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708901	C18H16O3S	312.4	C1C(CC(=O)C(=C1O)SC2=CC=C(C=C2)O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B1GHK4	NS(=O)(=O)c1ccc(Cc2c(nn(-c3nc(cs3)C(O)=O)c2C(F)(F)F)-c2cccc(c2)-c2ccccc2)cc1	Investigative	121461607	C27H19F3N4O4S2	584.6	C1=CC=C(C=C1)C2=CC(=CC=C2)C3=NN(C(=C3CC4=CC=C(C=C4)S(=O)(=O)N)C(F)(F)F)C5=NC(=CS5)C(=O)O	EC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B1JN7O	2-Benzylsulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708958	C19H18O2S	310.4	C1C(CC(=O)C(=C1O)SCC2=CC=CC=C2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B1N3FG	2-(5-Amino-3-phenyl-1H-pyrazol-1-yl)-1,3-thiazole-4-carboxylic acid	Investigative	1498344	C13H10N4O2S	286.31	C1=CC=C(C=C1)C2=NN(C(=C2)N)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B1RP7Y	2-(2-Chlorophenyl)sulfanyl-5-(2,6-dibromophenyl)-3-hydroxycyclohex-2-en-1-one	Investigative	118708931	C18H13Br2ClO2S	488.6	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=C(C=CC=C3Br)Br	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B1VL8G	N-(3-Chloro-2-methylphenyl)-2-{[4-(4-chlorophenyl)-5-cyano-6-oxo-1,6-dihydropyrimidin-2-yl]thio}acetamide	Investigative	135667153	C20H14Cl2N4O2S	445.3	CC1=C(C=CC=C1Cl)NC(=O)CSC2=NC(=C(C(=O)N2)C#N)C3=CC=C(C=C3)Cl	IC50 = 50200 nM	Poor binder
T15053	Lactate dehydrogenase A	B1VO2W	2-(4-Chlorophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	78425440	C18H15ClO2S	330.8	C1C(CC(=O)C(=C1O)SC2=CC=C(C=C2)Cl)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B23QRV	4-[[3-Phenyl-1-[4-(2,2,2-trifluoro-1-hydroxyethyl)-1,3-thiazol-2-yl]pyrazol-4-yl]methyl]benzenesulfonamide	Investigative	121457639	C21H17F3N4O3S2	494.5	C1=CC=C(C=C1)C2=NN(C=C2CC3=CC=C(C=C3)S(=O)(=O)N)C4=NC(=CS4)C(C(F)(F)F)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B28FUI	2-[4-(2,6-Dimethylphenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrile	Investigative	118708941	C21H19NO2S	349.4	CC1=C(C(=CC=C1)C)C2CC(=C(C(=O)C2)SC3=CC=CC=C3C#N)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B2BG8F	2-(3,5-Dichlorophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708910	C18H14Cl2O2S	365.3	C1C(CC(=O)C(=C1O)SC2=CC(=CC(=C2)Cl)Cl)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B2N5DJ	2-[5-(3,4-Dichlorophenyl)-3-oxo-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	137656179	C13H7Cl2N3O3S	356.2	C1=CC(=C(C=C1C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O)Cl)Cl	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B2V8YD	2-[3-Phenyl-4-[(4-sulfamoylbenzoyl)amino]pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid	Investigative	121457764	C20H15N5O5S2	469.5	C1=CC=C(C=C1)C2=NN(C=C2NC(=O)C3=CC=C(C=C3)S(=O)(=O)N)C4=NC(=CS4)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B30BOS	2-[5-[3-(2-Fluorophenyl)phenyl]-3-oxo-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	121461825	C19H12FN3O3S	381.4	C1=CC=C(C(=C1)C2=CC(=CC=C2)C3=CC(=O)N(N3)C4=NC(=CS4)C(=O)O)F	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B31RHZ	Sodium oxamate	Investigative	5242	C2H2NNaO3	111.03	C(=O)(C(=O)[O-])N.[Na+]	IC50 = 130600 nM	Poor binder
T15053	Lactate dehydrogenase A	B3AQD2	2-(2-Hydroxy-6-oxo-4-phenylcyclohexen-1-yl)sulfanylbenzamide	Investigative	118708884	C19H17NO3S	339.4	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2C(=O)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B3EUA7	2-[5-(Difluoromethyl)-3-phenylpyrazol-1-yl]-1,3-thiazole-4-carboxylic acid	Investigative	137654268	C14H9F2N3O2S	321.3	C1=CC=C(C=C1)C2=NN(C(=C2)C(F)F)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B3HSP7	3-Hydroxy-2-(2-hydroxyethylsulfanyl)-5-phenylcyclohex-2-en-1-one	Investigative	118708955	C14H16O3S	264.34	C1C(CC(=O)C(=C1O)SCCO)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B3JS6M	3-[5-Amino-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]benzamide	Investigative	72189814	C19H19N5O	333.4	C[C@H](C1=CC=CC=C1)NC2=NC(=CN=C2N)C3=CC(=CC=C3)C(=O)N	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B3KZR4	N-(4-Chlorophenyl)-2-{[4-(4-chlorophenyl)-5-cyano-6-oxo-1,6-dihydropyrimidin-2-yl]thio}acetamide	Investigative	135667152	C19H12Cl2N4O2S	431.3	C1=CC(=CC=C1C2=C(C(=O)NC(=N2)SCC(=O)NC3=CC=C(C=C3)Cl)C#N)Cl	IC50 = 55700 nM	Poor binder
T15053	Lactate dehydrogenase A	B3TDV0	Chembl4210558	Investigative	10440817	C40H52O24	916.8	COC1=CC(=CC(=C1O)OC)/C=C/C(=O)OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)O[C@]3([C@H]([C@@H]([C@H](O3)CO)O)OC(=O)/C=C/C4=CC(=C(C(=C4)OC)O)OC)CO)O)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)O	IC50 = 190700 nM	Poor binder
T15053	Lactate dehydrogenase A	B3VQE7	3-(2-Hydroxy-6-oxo-4-phenylcyclohexen-1-yl)sulfanylbenzamide	Investigative	118708894	C19H17NO3S	339.4	C1C(CC(=O)C(=C1O)SC2=CC=CC(=C2)C(=O)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B43CJT	4-[5-[(E)-[(3,4,5-Trimethoxybenzoyl)hydrazinylidene]methyl]furan-2-yl]benzoic acid	Investigative	122187852	C22H20N2O7	424.4	COC1=CC(=CC(=C1OC)OC)C(=O)N/N=C/C2=CC=C(O2)C3=CC=C(C=C3)C(=O)O	IC50 = 125000 nM	Poor binder
T15053	Lactate dehydrogenase A	B4BMR8	2-[5-(2-Fluorophenyl)-3-oxo-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	137645277	C13H8FN3O3S	305.29	C1=CC=C(C(=C1)C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O)F	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B5C6RO	2-[3-Oxo-5-(3-phenylphenyl)-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	137650978	C19H13N3O3S	363.4	C1=CC=C(C=C1)C2=CC(=CC=C2)C3=CC(=O)N(N3)C4=NC(=CS4)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B5F6QX	2-[5-(4-Methoxyphenyl)-3-oxo-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	121461900	C14H11N3O4S	317.32	COC1=CC=C(C=C1)C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B5K8WR	2-(2,4-Difluorophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708912	C18H14F2O2S	332.4	C1C(CC(=O)C(=C1O)SC2=C(C=C(C=C2)F)F)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B5LBN8	2-(3-Oxo-5-phenyl-1H-pyrazol-2-yl)-1,3-thiazole-4-carboxylic acid	Investigative	121461760	C13H9N3O3S	287.3	C1=CC=C(C=C1)C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B5LO2U	2-(3-Fluorophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708886	C18H15FO2S	314.4	C1C(CC(=O)C(=C1O)SC2=CC=CC(=C2)F)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B5NB6M	5-(2-Chlorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-one	Investigative	118708923	C18H14Cl2O2S	365.3	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=CC=CC=C3Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B5R3EW	2-[5-(2-Chlorophenyl)sulfanyl-4-hydroxy-6-oxo-2-phenyl-3H-pyran-2-yl]-N-methylacetamide	Investigative	118723533	C20H18ClNO4S	403.9	CNC(=O)CC1(CC(=C(C(=O)O1)SC2=CC=CC=C2Cl)O)C3=CC=CC=C3	IC50 = 59000 nM	Poor binder
T15053	Lactate dehydrogenase A	B5YUZ4	2-[4-(3-Chlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrile	Investigative	118708936	C19H14ClNO2S	355.8	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2C#N)C3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B61DXW	2-{[4-(4-Chlorophenyl)-5-cyano-6-oxo-1,6-dihydropyrimidin-2-yl]thio}-N-(2-methylphenyl)acetamide	Investigative	135667156	C20H15ClN4O2S	410.9	CC1=CC=CC=C1NC(=O)CSC2=NC(=C(C(=O)N2)C#N)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B6KF9I	N-(3-Chlorophenyl)-2-{[4-(4-chlorophenyl)-5-cyano-6-oxo-1,6-dihydropyrimidin-2-yl]thio}acetamide	Investigative	135667170	C19H12Cl2N4O2S	431.3	C1=CC(=CC(=C1)Cl)NC(=O)CSC2=NC(=C(C(=O)N2)C#N)C3=CC=C(C=C3)Cl	IC50 = 55800 nM	Poor binder
T15053	Lactate dehydrogenase A	B6XS0Q	2-(5-Acetamido-3-phenylpyrazol-1-yl)-1,3-thiazole-4-carboxylic acid	Investigative	137639861	C15H12N4O3S	328.3	CC(=O)NC1=CC(=NN1C2=NC(=CS2)C(=O)O)C3=CC=CC=C3	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B78JCN	3-[5-(Methanesulfonamido)-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]benzoic acid	Investigative	72191060	C20H20N4O4S	412.5	C[C@H](C1=CC=CC=C1)NC2=NC(=CN=C2NS(=O)(=O)C)C3=CC(=CC=C3)C(=O)O	IC50 = 71000 nM	Poor binder
T15053	Lactate dehydrogenase A	B7CJA9	3-[5-Amino-6-[[(1R)-1-phenylethyl]amino]pyridin-2-yl]benzoic acid	Investigative	72190758	C20H19N3O2	333.4	C[C@H](C1=CC=CC=C1)NC2=C(C=CC(=N2)C3=CC(=CC=C3)C(=O)O)N	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B7ILW1	2-[5-(2,4-Difluorophenyl)-3-oxo-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	121461805	C13H7F2N3O3S	323.28	C1=CC(=C(C=C1F)F)C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B7Q4WX	3-[5-(Methylamino)-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]benzoic acid	Investigative	72191058	C20H20N4O2	348.4	C[C@H](C1=CC=CC=C1)NC2=NC(=CN=C2NC)C3=CC(=CC=C3)C(=O)O	IC50 = 73000 nM	Poor binder
T15053	Lactate dehydrogenase A	B7XMR6	2-[4-(2,6-Dibromophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrile	Investigative	118708942	C19H13Br2NO2S	479.2	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2C#N)C3=C(C=CC=C3Br)Br	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B81MNE	3-Hydroxy-5-phenyl-2-[[3-(trifluoromethyl)phenyl]methylsulfanyl]cyclohex-2-en-1-one	Investigative	118708960	C20H17F3O2S	378.4	C1C(CC(=O)C(=C1O)SCC2=CC(=CC=C2)C(F)(F)F)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B87PYN	2-(2-Chlorophenyl)sulfanyl-5-[2-chloro-6-(trifluoromethyl)phenyl]-3-hydroxycyclohex-2-en-1-one	Investigative	118708929	C19H13Cl2F3O2S	433.3	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=C(C=CC=C3Cl)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B87XFO	2-{[4-(4-Chlorophenyl)-5-cyano-6-oxo-1,6-dihydropyrimidin-2-yl]thio}-N-(2-methoxyphenyl)acetamide	Investigative	135667148	C20H15ClN4O3S	426.9	COC1=CC=CC=C1NC(=O)CSC2=NC(=C(C(=O)N2)C#N)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B8DL5J	3-[6-Oxo-5-[[(1R)-1-phenylethyl]amino]-1H-pyrazin-3-yl]benzoic acid	Investigative	72191057	C19H17N3O3	335.4	C[C@H](C1=CC=CC=C1)NC2=NC(=CNC2=O)C3=CC(=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B8G1ZY	2-[5-(3,5-Difluorophenyl)-3-oxo-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	121461807	C13H7F2N3O3S	323.28	C1=C(C=C(C=C1F)F)C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	B8MXG9	3-Hydroxy-2-(2-methoxyphenyl)sulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708880	C19H18O3S	326.4	COC1=CC=CC=C1SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B8R1HN	5-(2-Chlorophenyl)sulfanyl-4-hydroxy-2-(oxan-4-yl)-2,3-dihydropyran-6-one	Investigative	118723152	C16H17ClO4S	340.8	C1COCCC1C2CC(=C(C(=O)O2)SC3=CC=CC=C3Cl)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B8TA3E	2-(3,5-Dimethylphenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708911	C20H20O2S	324.4	CC1=CC(=CC(=C1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O)C	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B8ZD2N	5-(4-Chlorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-one	Investigative	118708925	C18H14Cl2O2S	365.3	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B92COT	3-Hydroxy-5-phenyl-2-[2-(trifluoromethyl)phenyl]sulfanylcyclohex-2-en-1-one	Investigative	118708876	C19H15F3O2S	364.4	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2C(F)(F)F)C3=CC=CC=C3	IC50 ~ 66000 nM	Poor binder
T15053	Lactate dehydrogenase A	B93QRX	2-(4-Fluorophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708896	C18H15FO2S	314.4	C1C(CC(=O)C(=C1O)SC2=CC=C(C=C2)F)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B94IOM	2-(2-Chlorophenyl)sulfanyl-3-hydroxy-5-(4-methoxyphenyl)cyclohex-2-en-1-one	Investigative	118708926	C19H17ClO3S	360.9	COC1=CC=C(C=C1)C2CC(=C(C(=O)C2)SC3=CC=CC=C3Cl)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B97PEX	2-(4-Ethylphenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708899	C20H20O2S	324.4	CCC1=CC=C(C=C1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B9ALG8	5-(2-Chloroanilino)-4-hydroxy-2-phenyl-2,3-dihydro-1H-pyridin-6-one	Investigative	118723141	C17H15ClN2O2	314.8	C1C(NC(=O)C(=C1O)NC2=CC=CC=C2Cl)C3=CC=CC=C3	IC50 = 66000 nM	Poor binder
T15053	Lactate dehydrogenase A	B9FV5B	2-(2-Bromophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708874	C18H15BrO2S	375.3	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Br)C3=CC=CC=C3	IC50 = 53000 nM	Poor binder
T15053	Lactate dehydrogenase A	B9TP3N	2-(3-Chlorophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708887	C18H15ClO2S	330.8	C1C(CC(=O)C(=C1O)SC2=CC(=CC=C2)Cl)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	B9W3VF	3,6'-Disinapoyl sucrose	Investigative	11968389	C34H42O19	754.7	COC1=CC(=CC(=C1O)OC)/C=C/C(=O)OC[C@@H]2[C@H]([C@@H]([C@H]([C@H](O2)O[C@]3([C@H]([C@@H]([C@H](O3)CO)O)OC(=O)/C=C/C4=CC(=C(C(=C4)OC)O)OC)CO)O)O)O	IC50 = 90400 nM	Poor binder
T15053	Lactate dehydrogenase A	BAF29S	2-[3-(3,4-Difluorophenyl)-5-hydroxy-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid	Investigative	121457610	C13H7F2N3O3S	323.28	C1=CC(=C(C=C1C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O)F)F	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BB34KN	3-Hydroxy-5-phenyl-2-[4-(trifluoromethyl)phenyl]sulfanylcyclohex-2-en-1-one	Investigative	118708900	C19H15F3O2S	364.4	C1C(CC(=O)C(=C1O)SC2=CC=C(C=C2)C(F)(F)F)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BBU75I	5-(3-Bromo-2,6-dichlorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-one	Investigative	118708933	C18H12BrCl3O2S	478.6	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=C(C=CC(=C3Cl)Br)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BC25NZ	2-[5-Amino-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]benzoic acid	Investigative	72189817	C19H18N4O2	334.4	C[C@H](C1=CC=CC=C1)NC2=NC(=CN=C2N)C3=CC=CC=C3C(=O)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BCB31R	3-Hydroxy-2-(4-methylsulfanylphenyl)sulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708904	C19H18O2S2	342.5	CSC1=CC=C(C=C1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BCH40V	2-[(2,4-Dichlorophenyl)methylsulfanyl]-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708963	C19H16Cl2O2S	379.3	C1C(CC(=O)C(=C1O)SCC2=C(C=C(C=C2)Cl)Cl)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BCMI08	3-Hydroxy-2-(2-methylbutylsulfanyl)-5-phenylcyclohex-2-en-1-one	Investigative	118708954	C17H22O2S	290.4	CCC(C)CSC1=C(CC(CC1=O)C2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BCPG34	2-[4-[(4-Carbamoylphenyl)methyl]-3-oxo-5-(3-phenylphenyl)-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	121461772	C27H20N4O4S	496.5	C1=CC=C(C=C1)C2=CC(=CC=C2)C3=C(C(=O)N(N3)C4=NC(=CS4)C(=O)O)CC5=CC=C(C=C5)C(=O)N	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BCUZ04	2-Cyclohexylsulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708951	C18H22O2S	302.4	C1CCC(CC1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BD05LC	3-[5-Amino-6-[methyl-[(1R)-1-phenylethyl]amino]pyrazin-2-yl]benzoic acid	Investigative	72190459	C20H20N4O2	348.4	C[C@H](C1=CC=CC=C1)N(C)C2=NC(=CN=C2N)C3=CC(=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BD19JK	3-Hydroxy-2-(2-hydroxyphenyl)sulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708879	C18H16O3S	312.4	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BD9T8O	6-[3-[3-[3-[4-[[2-(5-Carboxypyridin-2-yl)sulfanylacetyl]amino]-2-chloro-5-methoxyphenoxy]propoxy]propoxy]-5-fluorophenyl]pyridine-3-carboxylic acid	Investigative	71562088	C33H31ClFN3O9S	700.1	COC1=CC(=C(C=C1NC(=O)CSC2=NC=C(C=C2)C(=O)O)Cl)OCCCOCCCOC3=CC(=CC(=C3)C4=NC=C(C=C4)C(=O)O)F	IC50 = 59000 nM	Poor binder
T15053	Lactate dehydrogenase A	BDO7H9	3-Hydroxy-2-(2-methylsulfonylphenyl)sulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708885	C19H18O4S2	374.5	CS(=O)(=O)C1=CC=CC=C1SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BDS43E	2-[3-(2-Chlorophenyl)-5-(trifluoromethyl)pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid	Investigative	137634582	C14H7ClF3N3O2S	373.7	C1=CC=C(C(=C1)C2=NN(C(=C2)C(F)(F)F)C3=NC(=CS3)C(=O)O)Cl	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BE4C7T	2-(2-Chlorophenyl)sulfanyl-5-(2,6-difluorophenyl)-3-hydroxycyclohex-2-en-1-one	Investigative	118708930	C18H13ClF2O2S	366.8	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=C(C=CC=C3F)F	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BEJL01	2-(4-Bromophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708897	C18H15BrO2S	375.3	C1C(CC(=O)C(=C1O)SC2=CC=C(C=C2)Br)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BEO18K	4-[[3-Oxo-5-(3-phenylphenyl)-2-[4-(2H-tetrazol-5-yl)-1,3-thiazol-2-yl]-1H-pyrazol-4-yl]methyl]benzenesulfonamide	Investigative	121457720	C26H20N8O3S2	556.6	C1=CC=C(C=C1)C2=CC(=CC=C2)C3=C(C(=O)N(N3)C4=NC(=CS4)C5=NNN=N5)CC6=CC=C(C=C6)S(=O)(=O)N	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BF20BA	4-[4-(3-Carboxyphenyl)triazol-1-yl]-1-hydroxyindole-2-carboxylic acid	Investigative	52920321	C18H12N4O5	364.3	C1=CC(=CC(=C1)C(=O)O)C2=CN(N=N2)C3=CC=CC4=C3C=C(N4O)C(=O)O	Ki = 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BFCU96	3-Hydroxy-2-(3-methoxyphenyl)sulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708891	C19H18O3S	326.4	COC1=CC(=CC=C1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BFJ37Q	5-(2-Chlorophenyl)sulfanyl-4-hydroxy-2-propan-2-yl-2,3-dihydropyran-6-one	Investigative	118723151	C14H15ClO3S	298.8	CC(C)C1CC(=C(C(=O)O1)SC2=CC=CC=C2Cl)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BFQ23A	3-[5-Amino-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]-N-methylsulfonylbenzamide	Investigative	72189815	C20H21N5O3S	411.5	C[C@H](C1=CC=CC=C1)NC2=NC(=CN=C2N)C3=CC(=CC=C3)C(=O)NS(=O)(=O)C	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BG0TE1	3-Hydroxy-2-(2-methylphenyl)sulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708875	C19H18O2S	310.4	CC1=CC=CC=C1SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BG1S5L	2-(3,4-Dimethylphenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708909	C20H20O2S	324.4	CC1=C(C=C(C=C1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O)C	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BG2TA8	3-[5-[(E)-[(2-Cyanoacetyl)hydrazinylidene]methyl]furan-2-yl]benzoic acid	Investigative	122186811	C15H11N3O4	297.26	C1=CC(=CC(=C1)C(=O)O)C2=CC=C(O2)/C=N/NC(=O)CC#N	IC50 = 115000 nM	Poor binder
T15053	Lactate dehydrogenase A	BG54OM	CCOC(=O)c1csc(n1)-n1nc(c(Cc2ccc(cc2)S(N)(=O)=O)c1C(F)(F)F)-c1cccc(c1)-c1ccccc1	Investigative	121461786	C29H23F3N4O4S2	612.6	CCOC(=O)C1=CSC(=N1)N2C(=C(C(=N2)C3=CC=CC(=C3)C4=CC=CC=C4)CC5=CC=C(C=C5)S(=O)(=O)N)C(F)(F)F	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BG9U4A	2-[[4-(4-Chlorophenyl)-5-cyano-6-oxo-1H-pyrimidin-2-yl]sulfanyl]-N-[4-(methylsulfamoyl)phenyl]acetamide	Investigative	136242871	C20H16ClN5O4S2	490	CNS(=O)(=O)C1=CC=C(C=C1)NC(=O)CSC2=NC(=C(C(=O)N2)C#N)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BGB20D	2-(3-Phenyl-5-propan-2-ylpyrazol-1-yl)-1,3-thiazole-4-carboxylic acid	Investigative	137641261	C16H15N3O2S	313.4	CC(C)C1=CC(=NN1C2=NC(=CS2)C(=O)O)C3=CC=CC=C3	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BGU6M5	3-Hydroxy-2-[(2-methylphenyl)methylsulfanyl]-5-phenylcyclohex-2-en-1-one	Investigative	118708959	C20H20O2S	324.4	CC1=CC=CC=C1CSC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BH57TI	2-[4-[[4-(Methylsulfamoyl)phenyl]methyl]-3-oxo-5-(3-phenylphenyl)-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	121461678	C27H22N4O5S2	546.6	CNS(=O)(=O)C1=CC=C(C=C1)CC2=C(NN(C2=O)C3=NC(=CS3)C(=O)O)C4=CC=CC(=C4)C5=CC=CC=C5	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BH5T7Z	5-(2-Bromo-6-chlorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-one	Investigative	118708928	C18H13BrCl2O2S	444.2	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=C(C=CC=C3Br)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BHJ45T	3-[5-[(E)-(1H-Indole-5-carbonylhydrazinylidene)methyl]furan-2-yl]benzoic acid	Investigative	122186810	C21H15N3O4	373.4	C1=CC(=CC(=C1)C(=O)O)C2=CC=C(O2)/C=N/NC(=O)C3=CC4=C(C=C3)NC=C4	IC50 = 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BI31EP	3-Hydroxy-2-[(4-methylphenyl)methylsulfanyl]-5-phenylcyclohex-2-en-1-one	Investigative	118708961	C20H20O2S	324.4	CC1=CC=C(C=C1)CSC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BJ06UY	6-[4-(3-Carboxyphenyl)triazol-1-yl]-1-hydroxyindole-2-carboxylic acid	Investigative	90667522	C18H12N4O5	364.3	C1=CC(=CC(=C1)C(=O)O)C2=CN(N=N2)C3=CC4=C(C=C3)C=C(N4O)C(=O)O	Ki = 50000 nM	Poor binder
T15053	Lactate dehydrogenase A	BJ2R4D	4-[5-Amino-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]thiophene-2-carboxylic acid	Investigative	72190139	C17H16N4O2S	340.4	C[C@H](C1=CC=CC=C1)NC2=NC(=CN=C2N)C3=CSC(=C3)C(=O)O	IC50 = 50000 nM	Poor binder
T15053	Lactate dehydrogenase A	BJ3H6U	3-Hydroxy-2-(3-methylbutan-2-ylsulfanyl)-5-phenylcyclohex-2-en-1-one	Investigative	118708952	C17H22O2S	290.4	CC(C)C(C)SC1=C(CC(CC1=O)C2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BJ7H5T	4-(2-Hydroxy-6-oxo-4-phenylcyclohexen-1-yl)sulfanylbenzoic acid	Investigative	118708903	C19H16O4S	340.4	C1C(CC(=O)C(=C1O)SC2=CC=C(C=C2)C(=O)O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BJ90IZ	2-(5-Naphthalen-1-yl-3-oxo-1H-pyrazol-2-yl)-1,3-thiazole-4-carboxylic acid	Investigative	137638998	C17H11N3O3S	337.4	C1=CC=C2C(=C1)C=CC=C2C3=CC(=O)N(N3)C4=NC(=CS4)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BJ9P5M	2-(3-Oxo-5-pyridin-4-yl-1H-pyrazol-2-yl)-1,3-thiazole-4-carboxylic acid	Investigative	137651644	C12H8N4O3S	288.28	C1=CN=CC=C1C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BJNK12	2-(2-Ethylphenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708877	C20H20O2S	324.4	CCC1=CC=CC=C1SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BJS8Z3	2-(2-Fluorophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708872	C18H15FO2S	314.4	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2F)C3=CC=CC=C3	IC50 = 53000 nM	Poor binder
T15053	Lactate dehydrogenase A	BJU7A4	2-(3,4-Dimethoxyphenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708908	C20H20O4S	356.4	COC1=C(C=C(C=C1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O)OC	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BK5GP7	Tetrahydro-NAD	Investigative	169266	C21H31N7O14P2	667.5	C1CC(=CN(C1)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O)C(=O)N	IC50 = 132000 nM	Poor binder
T15053	Lactate dehydrogenase A	BKC45J	2-[(4-Fluorophenyl)methylsulfanyl]-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708950	C19H17FO2S	328.4	C1C(CC(=O)C(=C1O)SCC2=CC=C(C=C2)F)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BKMA86	LDHA Inhibitor, 28	Investigative	57340474	C23H26N4O5S	470.5	CC1=NC2=C(S1)C=C(C=C2)NC(=O)CCNC(=O)NCCOC3=CC=C(C=C3)CCC(=O)O	IC50 = 86200 nM	Poor binder
T15053	Lactate dehydrogenase A	BKVO39	3-[5-[(E)-[(3,4,5-Trimethoxybenzoyl)hydrazinylidene]methyl]furan-3-yl]benzoic acid	Investigative	122186806	C22H20N2O7	424.4	COC1=CC(=CC(=C1OC)OC)C(=O)N/N=C/C2=CC(=CO2)C3=CC(=CC=C3)C(=O)O	IC50 = 52000 nM	Poor binder
T15053	Lactate dehydrogenase A	BL4C7P	2-(2-Hydroxy-6-oxo-4-phenylcyclohexen-1-yl)sulfanylbenzoic acid	Investigative	118708882	C19H16O4S	340.4	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2C(=O)O)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BLFG02	5-(3-Chlorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-one	Investigative	118708924	C18H14Cl2O2S	365.3	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=CC(=CC=C3)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BLJ15Q	2-(3-Aminophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708893	C18H17NO2S	311.4	C1C(CC(=O)C(=C1O)SC2=CC=CC(=C2)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BLOK14	2-(3-Bromophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708888	C18H15BrO2S	375.3	C1C(CC(=O)C(=C1O)SC2=CC(=CC=C2)Br)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BM02ZR	3-Hydroxy-2-(3-methylphenyl)sulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708889	C19H18O2S	310.4	CC1=CC(=CC=C1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BM0AR3	2-[3-(3-Chlorophenyl)-5-(trifluoromethyl)pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid	Investigative	137631546	C14H7ClF3N3O2S	373.7	C1=CC(=CC(=C1)Cl)C2=NN(C(=C2)C(F)(F)F)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BM5TB4	2',6'-Dichloro-4-((2-chlorophenyl)thio)-5-hydroxy-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one	Investigative	91668260	C18H13Cl3O2S	399.7	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=C(C=CC=C3Cl)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BMHC16	3-[5-Amino-6-[(1R)-1-phenylethoxy]pyrazin-2-yl]benzoic acid	Investigative	72190753	C19H17N3O3	335.4	C[C@H](C1=CC=CC=C1)OC2=NC(=CN=C2N)C3=CC(=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BMU1A2	5-[2,6-Bis(trifluoromethyl)phenyl]-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-one	Investigative	118708934	C20H13ClF6O2S	466.8	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=C(C=CC=C3C(F)(F)F)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BN30WQ	3-[5-[(E)-[(3,4,5-Trimethoxybenzoyl)hydrazinylidene]methyl]thiophen-2-yl]benzoic acid	Investigative	122186807	C22H20N2O6S	440.5	COC1=CC(=CC(=C1OC)OC)C(=O)N/N=C/C2=CC=C(S2)C3=CC(=CC=C3)C(=O)O	IC50 = 105000 nM	Poor binder
T15053	Lactate dehydrogenase A	BN3YQ0	2-(2-Chloro-6-methylphenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708917	C19H17ClO2S	344.9	CC1=C(C(=CC=C1)Cl)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BN8LD5	2-{[4-(4-Chlorophenyl)-5-cyano-6-oxo-1,6-dihydropyrimidin-2-yl]thio}-N-(2-ethylphenyl)acetamide	Investigative	135667157	C21H17ClN4O2S	424.9	CCC1=CC=CC=C1NC(=O)CSC2=NC(=C(C(=O)N2)C#N)C3=CC=C(C=C3)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BNBR65	3-Hydroxy-2-naphthalen-1-ylsulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708964	C22H18O2S	346.4	C1C(CC(=O)C(=C1O)SC2=CC=CC3=CC=CC=C32)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BNV2X9	2-(2,4-Dimethylphenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708919	C20H20O2S	324.4	CC1=CC(=C(C=C1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O)C	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BO0H6Q	2-[5-(2-Chlorophenyl)sulfanyl-4-hydroxy-6-oxo-2,3-dihydropyran-2-yl]benzonitrile	Investigative	118723147	C18H12ClNO3S	357.8	C1C(OC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=CC=CC=C3C#N	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BO9Y5R	2-[4-[2-Chloro-6-(trifluoromethyl)phenyl]-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrile	Investigative	118708940	C20H13ClF3NO2S	423.8	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2C#N)C3=C(C=CC=C3Cl)C(F)(F)F	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BOE0M8	3-Hydroxy-2-(4-methoxyphenyl)sulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708902	C19H18O3S	326.4	COC1=CC=C(C=C1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BONG28	3-Hydroxy-2-[(3-methylphenyl)methylsulfanyl]-5-phenylcyclohex-2-en-1-one	Investigative	118708949	C20H20O2S	324.4	CC1=CC(=CC=C1)CSC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BONK37	2-[4-(2-Chlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrile	Investigative	118708935	C19H14ClNO2S	355.8	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2C#N)C3=CC=CC=C3Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BP03ED	2-(2,3-Dichlorophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708914	C18H14Cl2O2S	365.3	C1C(CC(=O)C(=C1O)SC2=C(C(=CC=C2)Cl)Cl)C3=CC=CC=C3	IC50 = 63000 nM	Poor binder
T15053	Lactate dehydrogenase A	BP5H7S	Methyl 2-(2-hydroxy-6-oxo-4-phenylcyclohexen-1-yl)sulfanylacetate	Investigative	118708956	C15H16O4S	292.4	COC(=O)CSC1=C(CC(CC1=O)C2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BP86IG	2-[4-Benzyl-5-(3,4-difluorophenyl)-3-oxo-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	121461771	C20H13F2N3O3S	413.4	C1=CC=C(C=C1)CC2=C(NN(C2=O)C3=NC(=CS3)C(=O)O)C4=CC(=C(C=C4)F)F	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BP8OI0	3-Hydroxy-5-phenyl-2-propan-2-ylsulfanylcyclohex-2-en-1-one	Investigative	118708953	C15H18O2S	262.4	CC(C)SC1=C(CC(CC1=O)C2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BQ35VL	2-(2,5-Dimethylphenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708920	C20H20O2S	324.4	CC1=CC(=C(C=C1)C)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 64000 nM	Poor binder
T15053	Lactate dehydrogenase A	BQE84I	3-Hydroxy-5-phenyl-2-[3-(trifluoromethoxy)phenyl]sulfanylcyclohex-2-en-1-one	Investigative	118708892	C19H15F3O3S	380.4	C1C(CC(=O)C(=C1O)SC2=CC=CC(=C2)OC(F)(F)F)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BR57FZ	2-[4-(2-Bromo-6-chlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrile	Investigative	118708939	C19H13BrClNO2S	434.7	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2C#N)C3=C(C=CC=C3Br)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BR6YN9	Chembl4217921	Investigative	145969821	C12H8O8	280.19	C1=C(C(OC2=C1OC(=O)C3=CC(=C(C(=C32)O)O)O)O)O	IC50 = 102400 nM	Poor binder
T15053	Lactate dehydrogenase A	BRH2P4	3-Hydroxy-5-phenyl-2-pyridin-2-ylsulfanylcyclohex-2-en-1-one	Investigative	118708966	C17H15NO2S	297.4	C1C(CC(=O)C(=C1O)SC2=CC=CC=N2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BRO74M	2-(2,6-Dichlorophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708916	C18H14Cl2O2S	365.3	C1C(CC(=O)C(=C1O)SC2=C(C=CC=C2Cl)Cl)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BS3VW4	2-(3,4-Dichlorophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708907	C18H14Cl2O2S	365.3	C1C(CC(=O)C(=C1O)SC2=CC(=C(C=C2)Cl)Cl)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BS6D0M	2-[3-Phenyl-5-(trifluoromethyl)pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid	Investigative	1498318	C14H8F3N3O2S	339.29	C1=CC=C(C=C1)C2=NN(C(=C2)C(F)(F)F)C3=NC(=CS3)C(=O)O	EC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BSD5J9	2-[5-(4-Fluorophenyl)-3-oxo-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	121461896	C13H8FN3O3S	305.29	C1=CC(=CC=C1C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O)F	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BSG18M	Methyl 3-(2-hydroxy-6-oxo-4-phenylcyclohexen-1-yl)sulfanylpropanoate	Investigative	118708957	C16H18O4S	306.4	COC(=O)CCSC1=C(CC(CC1=O)C2=CC=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BSK15M	2-[3-Oxo-5-[3-(trifluoromethoxy)phenyl]-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	137655821	C14H8F3N3O4S	371.29	C1=CC(=CC(=C1)OC(F)(F)F)C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BSPE63	2-[3-Oxo-5-[3-(trifluoromethyl)phenyl]-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	137650206	C14H8F3N3O3S	355.29	C1=CC(=CC(=C1)C(F)(F)F)C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BT0JM6	2-{[4-(4-Chlorophenyl)-5-cyano-6-oxo-1,6-dihydropyrimidin-2-yl]thio}-N-(2,3-dimethylphenyl)acetamide	Investigative	135667151	C21H17ClN4O2S	424.9	CC1=C(C(=CC=C1)NC(=O)CSC2=NC(=C(C(=O)N2)C#N)C3=CC=C(C=C3)Cl)C	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BTB57A	5-beta-D-Ribofuranosylnicotinamide adenine dinucleotide	Investigative	444215	C21H27N7O14P2	663.4	C1=C(C=NC=C1C(=O)N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)(O)OP(=O)(O)OC[C@@H]3[C@H]([C@H]([C@@H](O3)N4C=NC5=C(N=CN=C54)N)O)O)O)O	Ki = 188000 nM	Poor binder
T15053	Lactate dehydrogenase A	BTD3W5	2-[4-(2,6-Dichlorophenyl)-2-hydroxy-6-oxocyclohexen-1-yl]sulfanylbenzonitrile	Investigative	118708938	C19H13Cl2NO2S	390.3	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2C#N)C3=C(C=CC=C3Cl)Cl	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BTP23W	2-(2,6-Dimethylphenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708921	C20H20O2S	324.4	CC1=C(C(=CC=C1)C)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BU5NY7	3-(2-Hydroxy-6-oxo-4-phenylcyclohexen-1-yl)sulfanylbenzenesulfonamide	Investigative	118708895	C18H17NO4S2	375.5	C1C(CC(=O)C(=C1O)SC2=CC(=CC=C2)S(=O)(=O)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BV0LF1	2-[5-(3,4-Difluorophenyl)-3-oxo-4-[(3-sulfamoylphenyl)methyl]-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	121461780	C20H14F2N4O5S2	492.5	C1=CC(=CC(=C1)S(=O)(=O)N)CC2=C(NN(C2=O)C3=NC(=CS3)C(=O)O)C4=CC(=C(C=C4)F)F	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BV93UH	NS(=O)(=O)c1ccc(NCc2cn(nc2-c2ccccc2)-c2nc(cs2)C(O)=O)cc1	Investigative	121461783	C20H17N5O4S2	455.5	C1=CC=C(C=C1)C2=NN(C=C2CNC3=CC=C(C=C3)S(=O)(=O)N)C4=NC(=CS4)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BVG5C8	2-(2,5-Dimethoxyphenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708922	C20H20O4S	356.4	COC1=CC(=C(C=C1)OC)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BVI1N0	2-(5-Cyclohexyl-3-oxo-1H-pyrazol-2-yl)-1,3-thiazole-4-carboxylic acid	Investigative	137639008	C13H15N3O3S	293.34	C1CCC(CC1)C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BVI6F5	2-[(6-Oxo-4-phenyl-1,6-dihydropyrimidin-2-yl)sulfanyl]-N-(4-sulfamoylphenyl)propanamide	Investigative	135505406	C19H18N4O4S2	430.5	CC(C(=O)NC1=CC=C(C=C1)S(=O)(=O)N)SC2=NC(=CC(=O)N2)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BW7FO9	5-(2-Chloro-6-fluorophenyl)-2-(2-chlorophenyl)sulfanyl-3-hydroxycyclohex-2-en-1-one	Investigative	118708927	C18H13Cl2FO2S	383.3	C1C(CC(=O)C(=C1O)SC2=CC=CC=C2Cl)C3=C(C=CC=C3Cl)F	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BW91LT	Methyl 2-(2-hydroxy-6-oxo-4-phenylcyclohexen-1-yl)sulfanylbenzoate	Investigative	118708883	C20H18O4S	354.4	COC(=O)C1=CC=CC=C1SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BWK3C7	3-Hydroxy-2-(4-methylphenyl)sulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708898	C19H18O2S	310.4	CC1=CC=C(C=C1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BX47IF	Ethyl 3-[5-amino-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]benzoate	Investigative	72189813	C21H22N4O2	362.4	CCOC(=O)C1=CC=CC(=C1)C2=CN=C(C(=N2)N[C@H](C)C3=CC=CC=C3)N	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BX6V7N	3-[5-Acetamido-6-[[(1R)-1-phenylethyl]amino]pyrazin-2-yl]benzoic acid	Investigative	72191059	C21H20N4O3	376.4	C[C@H](C1=CC=CC=C1)NC2=NC(=CN=C2NC(=O)C)C3=CC(=CC=C3)C(=O)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BXY6T8	2-(4-Aminophenyl)sulfanyl-3-hydroxy-5-phenylcyclohex-2-en-1-one	Investigative	118708905	C18H17NO2S	311.4	C1C(CC(=O)C(=C1O)SC2=CC=C(C=C2)N)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BY8X2J	2-(5-Methyl-3-phenylpyrazol-1-yl)-1,3-thiazole-4-carboxylic acid	Investigative	72547453	C14H11N3O2S	285.32	CC1=CC(=NN1C2=NC(=CS2)C(=O)O)C3=CC=CC=C3	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BYBC85	2-[5-(3-Fluorophenyl)-3-oxo-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	137636531	C13H8FN3O3S	305.29	C1=CC(=CC(=C1)F)C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BYPD85	3-Hydroxy-5-phenyl-2-[3-(trifluoromethyl)phenyl]sulfanylcyclohex-2-en-1-one	Investigative	118708890	C19H15F3O2S	364.4	C1C(CC(=O)C(=C1O)SC2=CC=CC(=C2)C(F)(F)F)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BYV01M	2-(3-Oxo-5-pyridin-2-yl-1H-pyrazol-2-yl)-1,3-thiazole-4-carboxylic acid	Investigative	137639445	C12H8N4O3S	288.28	C1=CC=NC(=C1)C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder
T15053	Lactate dehydrogenase A	BZ2TP4	3-Hydroxy-2-naphthalen-2-ylsulfanyl-5-phenylcyclohex-2-en-1-one	Investigative	118708965	C22H18O2S	346.4	C1C(CC(=O)C(=C1O)SC2=CC3=CC=CC=C3C=C2)C4=CC=CC=C4	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BZ4QS6	N-[4-(2-Hydroxy-6-oxo-4-phenylcyclohexen-1-yl)sulfanylphenyl]acetamide	Investigative	118708906	C20H19NO3S	353.4	CC(=O)NC1=CC=C(C=C1)SC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BZ8UF3	3-Hydroxy-2-[(4-methoxyphenyl)methylsulfanyl]-5-phenylcyclohex-2-en-1-one	Investigative	118708962	C20H20O3S	340.4	COC1=CC=C(C=C1)CSC2=C(CC(CC2=O)C3=CC=CC=C3)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BZC9V1	3-[5-Amino-6-(2-methoxyethylamino)pyrazin-2-yl]benzoic acid	Investigative	72190756	C14H16N4O3	288.3	COCCNC1=NC(=CN=C1N)C2=CC(=CC=C2)C(=O)O	IC50 ~ 100000 nM	Poor binder
T15053	Lactate dehydrogenase A	BZK8Q2	2-[5-(3-Chlorophenyl)-3-oxo-1H-pyrazol-2-yl]-1,3-thiazole-4-carboxylic acid	Investigative	137640502	C13H8ClN3O3S	321.74	C1=CC(=CC(=C1)Cl)C2=CC(=O)N(N2)C3=NC(=CS3)C(=O)O	IC50 ~ 57000 nM	Poor binder