TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T19368	Endothelial lipase	B1K2MS	2-Nonylphenylboronic Acid	Investigative	57401757	C15H25BO2	248.17	B(C1=CC=CC=C1CCCCCCCCC)(O)O	IC50 = 50000 nM	Poor binder
T19368	Endothelial lipase	B26OTH	1-Methyl-3-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-yl)-1-phenylurea	Investigative	44569863	C18H23N3O4S	377.5	CC1=C(C=C(O1)S(=O)(=O)N2CCCCC2)NC(=O)N(C)C3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T19368	Endothelial lipase	B4ZGN5	US8987314, Reference 2	Investigative	89962485	C24H25N3O2S	419.5	CC(C)C1=NOC(=C1)CNC(=O)C(C)(C)C2=NC3=C(S2)C=C(C=C3)C4=CC=CC=C4	IC50 ~ 62000 nM	Poor binder
T19368	Endothelial lipase	B6P4UX	2-Methyl-N-phenyl-5-(piperidin-1-ylsulfonyl)furan-3-carboxamide	Investigative	2809636	C17H20N2O4S	348.4	CC1=C(C=C(O1)S(=O)(=O)N2CCCCC2)C(=O)NC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T19368	Endothelial lipase	B9O3KE	US8987314, Reference 3	Investigative	89967321	C22H21N3O2S	391.5	CC1=NOC(=C1)CNC(=O)C(C)(C)C2=NC3=C(S2)C=C(C=C3)C4=CC=CC=C4	IC50 ~ 62000 nM	Poor binder
T19368	Endothelial lipase	B9Q1KN	1-(2-Methyl-4-(morpholinosulfonyl)phenyl)-3-phenylurea	Investigative	44569336	C18H21N3O4S	375.4	CC1=C(C=CC(=C1)S(=O)(=O)N2CCOCC2)NC(=O)NC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T19368	Endothelial lipase	BCY1P3	1-(2-Methyl-5-(piperidin-1-ylsulfonyl)-1H-pyrrol-3-yl)-3-phenylurea	Investigative	44569314	C17H22N4O3S	362.4	CC1=C(C=C(N1)S(=O)(=O)N2CCCCC2)NC(=O)NC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T19368	Endothelial lipase	BG3L9X	1-(2-Methyl-6-(piperidin-1-ylsulfonyl)pyridin-3-yl)-3-phenylurea	Investigative	44569369	C18H22N4O3S	374.5	CC1=C(C=CC(=N1)S(=O)(=O)N2CCCCC2)NC(=O)NC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T19368	Endothelial lipase	BGJ26K	1-(1-Methyl-3-(piperidin-1-ylsulfonyl)-1H-pyrazol-5-yl)-3-phenylurea	Investigative	44569316	C16H21N5O3S	363.4	CN1C(=CC(=N1)S(=O)(=O)N2CCCCC2)NC(=O)NC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T19368	Endothelial lipase	BJX8Q6	1-(2,4-Dimethyl-5-(piperidin-1-ylsulfonyl)furan-3-yl)-3-phenylurea	Investigative	44569312	C18H23N3O4S	377.5	CC1=C(OC(=C1NC(=O)NC2=CC=CC=C2)C)S(=O)(=O)N3CCCCC3	IC50 ~ 50000 nM	Poor binder
T19368	Endothelial lipase	BLRJ48	1-(1,2-Dimethyl-5-(piperidin-1-ylsulfonyl)-1H-pyrrol-3-yl)-3-phenylurea	Investigative	44569315	C18H24N4O3S	376.5	CC1=C(C=C(N1C)S(=O)(=O)N2CCCCC2)NC(=O)NC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T19368	Endothelial lipase	BQ3DC6	1-Benzyl-3-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-yl)urea	Investigative	44569829	C18H23N3O4S	377.5	CC1=C(C=C(O1)S(=O)(=O)N2CCCCC2)NC(=O)NCC3=CC=CC=C3	IC50 ~ 50000 nM	Poor binder
T19368	Endothelial lipase	BQ4U1V	3-[3-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]phenyl]propanoic acid	Investigative	57401758	C21H25BO4	352.2	B1(OC(C(O1)(C)C)(C)C)C2=CC=C(C=C2)C3=CC=CC(=C3)CCC(=O)O	IC50 = 95000 nM	Poor binder
T19368	Endothelial lipase	BRYQ28	1-(4-Chlorophenyl)-1-methyl-3-(2-methyl-5-(piperidin-1-ylsulfonyl)furan-3-yl)urea	Investigative	44569864	C18H22ClN3O4S	411.9	CC1=C(C=C(O1)S(=O)(=O)N2CCCCC2)NC(=O)N(C)C3=CC=C(C=C3)Cl	IC50 ~ 50000 nM	Poor binder