TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T20333 Macrophage colony-stimulating factor 1 receptor B51KGE 2-Methyl-N-phenyl-5-{[3-(trifluoromethyl)benzoyl]amino}benzamide Investigative 44561920 C22H17F3N2O2 398.4 CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(F)(F)F)C(=O)NC3=CC=CC=C3 IC50 ~ 50000 nM Poor binder T20333 Macrophage colony-stimulating factor 1 receptor B7OF9V JAK3 Inhibitor, Negative Control Investigative 11359024 C16H16ClN3O2 317.77 COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC=C3)OC.Cl IC50 ~ 50000 nM Poor binder T20333 Macrophage colony-stimulating factor 1 receptor BOT8V6 Methyl-phenyl-(2,6,7-trimethoxy-quinazolin-4-yl)-amine Investigative 44355543 C18H19N3O3 325.4 CN(C1=CC=CC=C1)C2=NC(=NC3=CC(=C(C=C32)OC)OC)OC IC50 ~ 50000 nM Poor binder T20333 Macrophage colony-stimulating factor 1 receptor BSEB16 2-[[1-Cyclopentyl-5-[1-(Oxetan-3-Yl)piperidin-4-Yl]pyrazol-3-Yl]amino]pyridine-4-Carbonitrile Investigative 91936970 C22H28N6O 392.5 C1CCC(C1)N2C(=CC(=N2)NC3=NC=CC(=C3)C#N)C4CCN(CC4)C5COC5 IC50 = 57000 nM Poor binder T20333 Macrophage colony-stimulating factor 1 receptor BT31KV (2-Chloro-6,7-dimethoxy-quinazolin-4-yl)-methyl-phenyl-amine Investigative 22692676 C17H16ClN3O2 329.8 CN(C1=CC=CC=C1)C2=NC(=NC3=CC(=C(C=C32)OC)OC)Cl IC50 ~ 50000 nM Poor binder T20333 Macrophage colony-stimulating factor 1 receptor D0L4HJ RPR-108518A Investigative 18770840 C19H22ClN3O5 407.8 COC1=CC(=CC(=C1OC)OC)NC2=NC=NC3=CC(=C(C=C32)OC)OC.Cl IC50 ~ 100000 nM Poor binder