TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T21123	Hypoxia-inducible factor 2 alpha	B0BGL6	Chembl4159084	Investigative	145960097	C16H8F5NO5S	421.3	C1=CC(=C(C(=C1OC2=CC(=CC(=C2)C#N)F)C(F)F)C(=O)O)S(=O)(=O)C(F)F	IC50 ~ 100000 nM	Poor binder
T21123	Hypoxia-inducible factor 2 alpha	B21XUF	(1R,4E,6E,10E,14S)-7-(2-Methoxypropan-2-yl)-4,10,14-trimethyl-15-oxabicyclo[12.1.0]pentadeca-4,6,10-triene	Investigative	54584323	C21H34O2	318.5	C/C/1=C\\CC[C@]2([C@H](O2)CC/C(=C/C=C(\\CC1)/C(C)(C)OC)/C)C	EC50 = 148900 nM	Poor binder
T21123	Hypoxia-inducible factor 2 alpha	B7OW2Q	Chembl4163733	Investigative	117942585	C15H9ClF4O5S	412.7	COC(=O)C1=C(C=CC(=C1)S(=O)(=O)C(F)(F)F)OC2=CC(=CC(=C2)Cl)F	IC50 = 52900 nM	Poor binder
T21123	Hypoxia-inducible factor 2 alpha	BDO1J9	(1R,2E,6R,8S,11E)-3,8,12,16-Tetramethyl-7,18-dioxatricyclo[13.3.0.06,8]octadeca-2,11,15-triene	Investigative	54585297	C20H30O2	302.5	C/C/1=C\\CC[C@]2([C@H](O2)CC/C(=C/[C@@H]3C(=C(CO3)C)CC1)/C)C	EC50 = 183300 nM	Poor binder
T21123	Hypoxia-inducible factor 2 alpha	BF4XY5	(1R,3S,14S)-6,10,14-Trimethyl-3-(prop-1-en-2-yl)-15-oxabicyclo[12.1.0]pentadeca-6,10-dien-5-one	Investigative	54586240	C20H30O2	302.5	CC1=CCC[C@]2([C@H](O2)C[C@@H](CC(=O)/C(=C/CC1)/C)C(=C)C)C	EC50 = 107500 nM	Poor binder
T21123	Hypoxia-inducible factor 2 alpha	BLO0V6	7-Methoxy-1,2,6-trimethylisoquinoline-3,5,8-trione	Investigative	44566893	C13H13NO4	247.25	CC1=C(C(=O)C2=C(N(C(=O)C=C2C1=O)C)C)OC	EC50 ~ 100000 nM	Poor binder
T21123	Hypoxia-inducible factor 2 alpha	BMW74R	Aaptamine	Investigative	122826	C13H12N2O2	228.25	COC1=C(C2=NC=CC3=C2C(=C1)C=CN3)OC	EC50 ~ 100000 nM	Poor binder
T21123	Hypoxia-inducible factor 2 alpha	BW3N6V	Xestoquinone	Investigative	122838	C20H14O4	318.3	C[C@@]12CCCC3=COC(=C31)C(=O)C4=C2C=C5C(=O)C=CC(=O)C5=C4	EC50 ~ 100000 nM	Poor binder
T21123	Hypoxia-inducible factor 2 alpha	BZJX01	[(1S,2R,5S,10R,11S,13R,16S,17S,18S,20S)-17-Acetyl-18-hydroxy-2,6,6,20-tetramethyl-15-oxo-14-oxapentacyclo[11.6.1.02,11.05,10.016,20]icosan-10-yl]methyl acetate	Investigative	23245942	C28H42O6	474.6	CC(=O)[C@@H]1[C@H](C[C@H]2[C@@]3(CC[C@@H]4[C@@]([C@H]3C[C@@H]5[C@@]2([C@H]1C(=O)O5)C)(CCCC4(C)C)COC(=O)C)C)O	EC50 ~ 100000 nM	Poor binder