TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T21865	P-selectin glycoprotein ligand 1	D02AUB	Bimosiamose	Phase 2a	9811353	C46H54O16	862.9	C1=CC(=CC(=C1)C2=C(C=CC(=C2)CCCCCCC3=CC(=C(C=C3)O[C@@H]4[C@H]([C@H]([C@@H]([C@H](O4)CO)O)O)O)C5=CC=CC(=C5)CC(=O)O)O[C@@H]6[C@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)CC(=O)O	IC50 = 70000 nM	Poor binder
T21865	P-selectin glycoprotein ligand 1	D0Z0AM	PSI-697	Phase 1	12004316	C21H18ClNO3	367.8	C1CCC2=C(C1)C=CC3=C(C(=C(N=C23)CC4=CC=C(C=C4)Cl)O)C(=O)O	IC50 = 150000 nM	Poor binder
T21865	P-selectin glycoprotein ligand 1	B8PCW0	2-(4-Chlorophenyl)-3-hydroxy-8-(thien-3-yl)quinoline-4-carboxylicacid	Investigative	16100014	C20H12ClNO3S	381.8	C1=CC2=C(C(=C(N=C2C(=C1)C3=CSC=C3)C4=CC=C(C=C4)Cl)O)C(=O)O	IC50 = 175000 nM	Poor binder
T21865	P-selectin glycoprotein ligand 1	BD6T8H	6-Bromo-2-(4-chlorophenyl)-3-hydroxy-8-methylquinoline-4-carboxylic acid	Investigative	16099971	C17H11BrClNO3	392.6	CC1=CC(=CC2=C(C(=C(N=C12)C3=CC=C(C=C3)Cl)O)C(=O)O)Br	IC50 = 125000 nM	Poor binder
T21865	P-selectin glycoprotein ligand 1	BEFR63	3-Hydroxy-7,8-dimethyl-2-(3-(trifluoromethoxy)phenyl)quinoline-4-carboxylic acid	Investigative	16099944	C19H14F3NO4	377.3	CC1=C(C2=NC(=C(C(=C2C=C1)C(=O)O)O)C3=CC(=CC=C3)OC(F)(F)F)C	IC50 = 200000 nM	Poor binder
T21865	P-selectin glycoprotein ligand 1	BI9ON2	8-Sec-butyl-2-(4-chlorophenyl)-3-hydroxyquinoline-4-carboxylicacid	Investigative	16099968	C20H18ClNO3	355.8	CCC(C)C1=CC=CC2=C(C(=C(N=C21)C3=CC=C(C=C3)Cl)O)C(=O)O	IC50 = 75000 nM	Poor binder
T21865	P-selectin glycoprotein ligand 1	BIWF02	2-(4-Chlorophenyl)-3-hydroxy-8-phenylquinoline-4-carboxylic acid	Investigative	16099923	C22H14ClNO3	375.8	C1=CC=C(C=C1)C2=CC=CC3=C(C(=C(N=C32)C4=CC=C(C=C4)Cl)O)C(=O)O	IC50 = 200000 nM	Poor binder
T21865	P-selectin glycoprotein ligand 1	BW63MK	3-Hydroxy-2-(1-phenylethyl)-7,8,9,10-tetrahydrobenzo[h]quinoline-4-carboxylic acid	Investigative	46915502	C22H21NO3	347.4	CC(C1=CC=CC=C1)C2=C(C(=C3C=CC4=C(C3=N2)CCCC4)C(=O)O)O	IC50 = 175000 nM	Poor binder