TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T21945	Norepinephrine transporter	B10UFN	2-(Benzhydrylsulfinylmethyl)-3-chlorothiophene	Investigative	137649584	C18H15ClOS2	346.9	C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC3=C(C=CS3)Cl	IC50 = 188100 nM	Poor binder
T21945	Norepinephrine transporter	B1INP4	4-(Benzhydrylsulfinylmethyl)-2-bromothiophene	Investigative	137649990	C18H15BrOS2	391.3	C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC3=CSC(=C3)Br	IC50 = 67200 nM	Poor binder
T21945	Norepinephrine transporter	B26CVM	4-Methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide	Investigative	743974	C16H19NO3S	305.4	CC1=CC(=C(C(=C1)C)NS(=O)(=O)C2=CC=C(C=C2)OC)C	IC50 ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	B29NIY	3-(Benzhydrylsulfinylmethyl)-2-bromothiophene	Investigative	137643954	C18H15BrOS2	391.3	C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC3=C(SC=C3)Br	IC50 = 144200 nM	Poor binder
T21945	Norepinephrine transporter	B2E5ZF	3-(2-Bromo-9H-fluoren-9-yl)-8-methyl-8-aza-bicyclo[3.2.1]octan-3-ol	Investigative	44405893	C21H22BrNO	384.3	CN1C2CCC1CC(C2)(C3C4=CC=CC=C4C5=C3C=C(C=C5)Br)O	IC50 = 62600 nM	Poor binder
T21945	Norepinephrine transporter	B2F1KT	(cis)-2-(5-Bromopentyl)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one	Investigative	25258806	C21H27BrN2O3	435.4	COC1=C(C=C(C=C1)C2=NN(C(=O)[C@H]3[C@@H]2CC=CC3)CCCCCBr)OC	IC50 ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	B2PXF6	2-[[(4-Methylphenyl)-phenylmethyl]sulfinylmethyl]thiophene	Investigative	137637663	C19H18OS2	326.5	CC1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC3=CC=CS3	IC50 = 152500 nM	Poor binder
T21945	Norepinephrine transporter	B3B8DP	N-Ethyl-2-pyrrolidin-1-yl-N-{2-[2-(trifluoromethoxy)phenyl]-ethyl}ethanamine	Investigative	24878953	C17H25F3N2O	330.4	CCN(CCC1=CC=CC=C1OC(F)(F)F)CCN2CCCC2	Ki ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	B3SAG0	(2S,3S)-2-(4-Methoxyphenyl)-3,5,5-trimethylmorpholin-2-ol	Investigative	46837782	C14H21NO3	251.32	C[C@H]1[C@@](OCC(N1)(C)C)(C2=CC=C(C=C2)OC)O	IC50 ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	B3ZN2B	N-Cyclobutyl-2-(3,4-dichlorophenyl)cyclopent-1-enecarboxamide	Investigative	44443878	C16H17Cl2NO	310.2	C1CC(C1)NC(=O)C2=C(CCC2)C3=CC(=C(C=C3)Cl)Cl	Ki = 50000 nM	Poor binder
T21945	Norepinephrine transporter	B47JCP	N-Methyl-2-piperidin-1-yl-N-{2-[4-(trifluoromethoxy)phenyl]-ethyl}ethanamine	Investigative	24863962	C17H25F3N2O	330.4	CN(CCC1=CC=C(C=C1)OC(F)(F)F)CCN2CCCCC2	Ki ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	B4ER7L	4-Hydroxy Duloxetine	Investigative	29981497	C18H19NO2S	313.4	CNCC[C@@H](C1=CC=CS1)OC2=CC=C(C3=CC=CC=C32)O	Ki = 97100 nM	Poor binder
T21945	Norepinephrine transporter	B5D2PQ	O-Methylcorypalline	Investigative	27694	C12H17NO2	207.27	CN1CCC2=CC(=C(C=C2C1)OC)OC	Ki = 128900 nM	Poor binder
T21945	Norepinephrine transporter	B5EOA1	2-[(1R)-3-Amino-1-(1,2-oxazol-5-yl)propoxy]-6-(trifluoromethyl)pyridine-3-carbonitrile;oxalic acid	Investigative	54580936	C15H13F3N4O6	402.28	C1=CC(=NC(=C1C#N)O[C@H](CCN)C2=CC=NO2)C(F)(F)F.C(=O)(C(=O)O)O	IC50 ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	B60AOI	(cis)-4-(3,4-Dimethoxyphenyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one	Investigative	11044358	C16H18N2O3	286.33	COC1=C(C=C(C=C1)C2=NNC(=O)[C@H]3[C@@H]2CC=CC3)OC	IC50 ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	B6H8MO	N-Methyl-2-pyrrolidin-1-yl-N-{2-[2-(trifluoromethoxy)phenyl]-ethyl}ethanamine	Investigative	24879008	C16H23F3N2O	316.36	CN(CCC1=CC=CC=C1OC(F)(F)F)CCN2CCCC2	Ki ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	B6NM8T	3-(9H-Fluoren-9-yl)-8-methyl-8-aza-bicyclo[3.2.1]octan-3-ol	Investigative	12646716	C21H23NO	305.4	CN1C2CCC1CC(C2)(C3C4=CC=CC=C4C5=CC=CC=C35)O	IC50 = 158000 nM	Poor binder
T21945	Norepinephrine transporter	B78YXV	3-Biphenyl-2-yl-8-methyl-8-aza-bicyclo[3.2.1]octan-3-ol	Investigative	44405897	C20H23NO	293.4	CN1C2CCC1CC(C2)(C3=CC=CC=C3C4=CC=CC=C4)O	IC50 = 66300 nM	Poor binder
T21945	Norepinephrine transporter	B7FA5K	Cyclohexyl 2-(3,4-dichlorophenyl)cyclopent-1-enecarboxylate	Investigative	44443892	C18H20Cl2O2	339.3	C1CCC(CC1)OC(=O)C2=C(CCC2)C3=CC(=C(C=C3)Cl)Cl	Ki = 130000 nM	Poor binder
T21945	Norepinephrine transporter	B7ICB5	N-Ethyl-2-piperidin-1-yl-N-{2-[4-(trifluoromethoxy)phenyl]-ethyl}ethanamine	Investigative	24878951	C18H27F3N2O	344.4	CCN(CCC1=CC=C(C=C1)OC(F)(F)F)CCN2CCCCC2	Ki ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	B9JR4F	Methyl 2-(3-chlorophenyl)cyclohept-1-enecarboxylate	Investigative	44429221	C15H17ClO2	264.74	COC(=O)C1=C(CCCCC1)C2=CC(=CC=C2)Cl	Ki = 85000 nM	Poor binder
T21945	Norepinephrine transporter	B9ZWL4	Methyl 2-(4-chlorophenyl)cyclopent-1-enecarboxylate	Investigative	44429190	C13H13ClO2	236.69	COC(=O)C1=C(CCC1)C2=CC=C(C=C2)Cl	Ki = 178000 nM	Poor binder
T21945	Norepinephrine transporter	BA0Y6B	[5-(5-Fluoro-2-methoxyphenyl)oxolan-2-yl]methanamine	Investigative	11492305	C12H16FNO2	225.26	COC1=C(C=C(C=C1)F)C2CCC(O2)CN	Ki = 57020 nM	Poor binder
T21945	Norepinephrine transporter	BB54SJ	Methyl 2-(4-chlorophenyl)cyclohept-1-enecarboxylate	Investigative	44429219	C15H17ClO2	264.74	COC(=O)C1=C(CCCCC1)C2=CC=C(C=C2)Cl	Ki = 84000 nM	Poor binder
T21945	Norepinephrine transporter	BBS6U9	2,2,2-Trifluoroethyl 2-(3,4-dichlorophenyl)cyclopent-1-enecarboxylate	Investigative	44443896	C14H11Cl2F3O2	339.1	C1CC(=C(C1)C(=O)OCC(F)(F)F)C2=CC(=C(C=C2)Cl)Cl	Ki = 170000 nM	Poor binder
T21945	Norepinephrine transporter	BCMN45	Methyl 2-(4-nitrophenyl)cyclopent-1-enecarboxylate	Investigative	44429199	C13H13NO4	247.25	COC(=O)C1=C(CCC1)C2=CC=C(C=C2)[N+](=O)[O-]	Ki = 111000 nM	Poor binder
T21945	Norepinephrine transporter	BDF02K	(cis)-4-(3,4-Dimethoxyphenyl)-2-(5-((S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propylamino)pentyl)-4a,5,8,8a-tetrahydrophthalazin-1(2H)-one	Investigative	46227269	C38H43N3O4S	637.8	COC1=C(C=C(C=C1)C2=NN(C(=O)[C@H]3[C@@H]2CC=CC3)CCCCCNCC[C@@H](C4=CC=CS4)OC5=CC=CC6=CC=CC=C65)OC	Ki ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	BE7LO2	N-(4-(Trifluoromethoxy)phenethyl)-N-methyl-2-(pyrrolidin-1-yl)ethanamine	Investigative	24863961	C16H23F3N2O	316.36	CN(CCC1=CC=C(C=C1)OC(F)(F)F)CCN2CCCC2	Ki ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	BGH80W	3,5,5-Trimethyl-2-(pyridin-3-yl)morpholin-2-ol	Investigative	49799236	C12H18N2O2	222.28	CC1C(OCC(N1)(C)C)(C2=CN=CC=C2)O	IC50 ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	BGK5P8	3-(Benzhydrylsulfinylmethyl)thiophene	Investigative	137633241	C18H16OS2	312.5	C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC3=CSC=C3	IC50 = 57600 nM	Poor binder
T21945	Norepinephrine transporter	BHEM18	Methyl 2-(biphenyl-4-yl)cycloheptanecarboxylate	Investigative	44429400	C21H24O2	308.4	COC(=O)[C@@H]1CCCCC[C@@H]1C2=CC=C(C=C2)C3=CC=CC=C3	Ki = 51000 nM	Poor binder
T21945	Norepinephrine transporter	BIW4Z7	m-Tolyl 2-(3,4-dichlorophenyl)cyclopent-1-enecarboxylate	Investigative	23661687	C19H16Cl2O2	347.2	CC1=CC(=CC=C1)OC(=O)C2=C(CCC2)C3=CC(=C(C=C3)Cl)Cl	Ki ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	BJ31AZ	2-[Bis(4-fluorophenyl)methylsulfinylmethyl]thiophene	Investigative	137632704	C18H14F2OS2	348.4	C1=CSC(=C1)CS(=O)C(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F	IC50 = 112600 nM	Poor binder
T21945	Norepinephrine transporter	BJM49K	5-(Benzhydrylsulfinylmethyl)-3-(trifluoromethyl)-1,2,4-oxadiazole	Investigative	137657462	C17H13F3N2O2S	366.4	C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC3=NC(=NO3)C(F)(F)F	IC50 = 71000 nM	Poor binder
T21945	Norepinephrine transporter	BK1YA0	(1S,5R)-N-[Bis(4-fluorophenyl)methyl]-8-methyl-8-azabicyclo[3.2.1]octan-3-amine	Investigative	76309752	C21H24F2N2	342.4	CN1[C@@H]2CC[C@H]1CC(C2)NC(C3=CC=C(C=C3)F)C4=CC=C(C=C4)F	Ki = 152000 nM	Poor binder
T21945	Norepinephrine transporter	BK3MR2	4-(3,4-Dimethoxy-phenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one	Investigative	22337182	C16H18N2O3	286.33	COC1=C(C=C(C=C1)C2=NNC(=O)C3C2CC=CC3)OC	Ki ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	BL6A8G	Methyl 2-(4-tert-butylphenyl)cyclohept-1-enecarboxylate	Investigative	44429402	C19H26O2	286.4	CC(C)(C)C1=CC=C(C=C1)C2=C(CCCCC2)C(=O)OC	Ki = 62000 nM	Poor binder
T21945	Norepinephrine transporter	BMJA03	Phenyl 2-(3,4-dichlorophenyl)cyclopent-1-enecarboxylate	Investigative	44443897	C18H14Cl2O2	333.2	C1CC(=C(C1)C(=O)OC2=CC=CC=C2)C3=CC(=C(C=C3)Cl)Cl	Ki = 85000 nM	Poor binder
T21945	Norepinephrine transporter	BMK53S	3-(9H-Fluoren-9-yl)-8-methyl-8-azabicyclo[3.2.1]oct-2-ene	Investigative	44405845	C21H21N	287.4	CN1C2CCC1C=C(C2)C3C4=CC=CC=C4C5=CC=CC=C35	IC50 = 82700 nM	Poor binder
T21945	Norepinephrine transporter	BPNJ26	Methyl 2-(4-tert-butylphenyl)cycloheptanecarboxylate	Investigative	44429401	C19H28O2	288.4	CC(C)(C)C1=CC=C(C=C1)[C@H]2CCCCC[C@H]2C(=O)OC	Ki = 94000 nM	Poor binder
T21945	Norepinephrine transporter	BQH62U	[(2R,5R)-5-(5-Fluoro-2-methoxyphenyl)oxolan-2-yl]methanamine	Investigative	44590643	C12H16FNO2	225.26	COC1=C(C=C(C=C1)F)[C@H]2CC[C@@H](O2)CN	Ki = 71990 nM	Poor binder
T21945	Norepinephrine transporter	BR15OM	Methyl 2-(naphthalen-2-yl)cyclohex-1-enecarboxylate	Investigative	44429203	C18H18O2	266.3	COC(=O)C1=C(CCCC1)C2=CC3=CC=CC=C3C=C2	Ki = 81000 nM	Poor binder
T21945	Norepinephrine transporter	BT4A9G	2-(5-Bromo-pentyl)-4-(3,4-dimethoxyphenyl)-4a,5,8,8a-tetrahydro-2H-phthalazin-1-one	Investigative	22337167	C21H27BrN2O3	435.4	COC1=C(C=C(C=C1)C2=NN(C(=O)C3C2CC=CC3)CCCCCBr)OC	IC50 ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	BU4O6T	5-(Benzhydrylsulfinylmethyl)-3H-1,3,4-thiadiazol-2-one	Investigative	137631557	C16H14N2O2S2	330.4	C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC3=NNC(=O)S3	IC50 = 85700 nM	Poor binder
T21945	Norepinephrine transporter	BU6K1H	N-Ethyl-2-pyrrolidin-1-yl-N-{2-[4-(trifluoromethoxy)phenyl]-ethyl}ethanamine	Investigative	24879005	C17H25F3N2O	330.4	CCN(CCC1=CC=C(C=C1)OC(F)(F)F)CCN2CCCC2	Ki ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	BU8PE0	N-Ethyl-2-piperidin-1-yl-N-{2-[2-(trifluoromethoxy)phenyl]-ethyl}ethanamine	Investigative	24879001	C18H27F3N2O	344.4	CCN(CCC1=CC=CC=C1OC(F)(F)F)CCN2CCCCC2	Ki = 58100 nM	Poor binder
T21945	Norepinephrine transporter	BV5C3X	Methyl 2-(3-nitrophenyl)cyclohexene-1-carboxylate	Investigative	44429214	C14H15NO4	261.269	COC(=O)C1=C(CCCC1)C2=CC(=CC=C2)[N+](=O)[O-]	Ki = 121000 nM	Poor binder
T21945	Norepinephrine transporter	BV98NH	N,N-Dimethyl(2-(naphthalen-1-yl)cyclopropyl)methanamine	Investigative	44444517	C16H19N	225.33	CN(C)CC1CC1C2=CC=CC3=CC=CC=C32	IC50 = 68000 nM	Poor binder
T21945	Norepinephrine transporter	BW49RA	2-(Benzhydrylsulfinylmethyl)-5-chlorothiophene	Investigative	137656786	C18H15ClOS2	346.9	C1=CC=C(C=C1)C(C2=CC=CC=C2)S(=O)CC3=CC=C(S3)Cl	IC50 = 68400 nM	Poor binder
T21945	Norepinephrine transporter	BW5OB6	Furan-2-ylmethyl 2-(3,4-dichlorophenyl)cyclopent-1-enecarboxylate	Investigative	44443900	C17H14Cl2O3	337.2	C1CC(=C(C1)C(=O)OCC2=CC=CO2)C3=CC(=C(C=C3)Cl)Cl	Ki = 61000 nM	Poor binder
T21945	Norepinephrine transporter	BWKI18	3-(2-((Dimethylamino)methyl)cyclopropyl)-1H-indazole-5-carbonitrile	Investigative	9834659	C14H16N4	240.3	CN(C)CC1CC1C2=C3C=C(C=CC3=NN2)C#N	IC50 ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	BX79MS	N-Methyl-2-piperidin-1-yl-N-{2-[2-(trifluoromethoxy)phenyl]-ethyl}ethanamine	Investigative	24879010	C17H25F3N2O	330.4	CN(CCC1=CC=CC=C1OC(F)(F)F)CCN2CCCCC2	Ki ~ 100000 nM	Poor binder
T21945	Norepinephrine transporter	BY0ZG5	5-(Benzhydrylsulfinylmethyl)-2-methoxy-2,3-dihydro-1,3,4-thiadiazole	Investigative	137646374	C17H18N2O2S2	346.5	COC1NN=C(S1)CS(=O)C(C2=CC=CC=C2)C3=CC=CC=C3	IC50 = 145800 nM	Poor binder
T21945	Norepinephrine transporter	BZ6C4F	3-alpha-(4-Methylphenyl)-2-beta-(3,4-dimethoxyphenyl)tropane	Investigative	44421485	C23H29NO2	351.5	CC1=CC=C(C=C1)[C@@H]2CC3CCC([C@H]2C4=CC(=C(C=C4)OC)OC)N3C	IC50 = 78000 nM	Poor binder
T21945	Norepinephrine transporter	BZ9S7Y	Methyl 2-(naphthalen-2-yl)cyclohept-1-enecarboxylate	Investigative	44429222	C19H20O2	280.4	COC(=O)C1=C(CCCCC1)C2=CC3=CC=CC=C3C=C2	Ki = 68000 nM	Poor binder
T21945	Norepinephrine transporter	D0FS4V	Bip-tyr-thr-pro-thr(obzl)-gly	Investigative	44413375	C50H61N7O12	952.1	C[C@H]([C@@H](C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)OCC2=CC=CC=C2)C(=O)NCC(=O)O)NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)[C@H](C(C)C4=CC=C(C=C4)C5=CC=C(C=C5)C[C@@H](C(=O)O)N)N)O	IC50 = 90000 nM	Poor binder