TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T22939	Progesterone receptor	D07KSG	Tamoxifen	Approved	2733526	C26H29NO	371.5	CC/C(=C(\\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T22939	Progesterone receptor	D0JO7Y	Fulvestrant	Approved	104741	C32H47F5O3S	606.8	C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)[C@@H](CC4=C3C=CC(=C4)O)CCCCCCCCCS(=O)CCCC(C(F)(F)F)(F)F	IC50 ~ 100000 nM	Poor binder
T22939	Progesterone receptor	B4XCA9	6-(5-Chlorothiophen-2-yl)chromen-2-one	Investigative	53379701	C13H7ClO2S	262.71	C1=CC2=C(C=CC(=O)O2)C=C1C3=CC=C(S3)Cl	IC50 = 50500 nM	Poor binder
T22939	Progesterone receptor	B8FP5L	(E)-3-[4-[(1R,3R)-2-(2-Hydroxyethyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]phenyl]prop-2-enoic acid	Investigative	122192187	C23H24N2O3	376.4	C[C@@H]1CC2=C([C@H](N1CCO)C3=CC=C(C=C3)/C=C/C(=O)O)NC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder
T22939	Progesterone receptor	BB1DT2	Afimoxifene	Investigative	63062	C26H29NO2	387.5	CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T22939	Progesterone receptor	BCRB42	(E)-3-[4-[(1R,3R)-2-[(2R)-3-Hydroxy-2-methylpropyl]-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]phenyl]prop-2-enoic acid	Investigative	122192189	C25H28N2O3	404.5	C[C@@H]1CC2=C([C@H](N1C[C@@H](C)CO)C3=CC=C(C=C3)/C=C/C(=O)O)NC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder
T22939	Progesterone receptor	BGB2L4	1-Methyl-3-phenyl-2,4(1H,3H)-quinazolinedione	Investigative	242636	C15H12N2O2	252.27	CN1C2=CC=CC=C2C(=O)N(C1=O)C3=CC=CC=C3	IC50 = 84000 nM	Poor binder
T22939	Progesterone receptor	BI76ZJ	2-[1-(4-Chlorophenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]ethanol	Investigative	122192181	C19H19ClN2O	326.8	C1CN(C(C2=C1C3=CC=CC=C3N2)C4=CC=C(C=C4)Cl)CCO	IC50 ~ 100000 nM	Poor binder
T22939	Progesterone receptor	BKP16B	3-[(1R,3R)-1-(4-Chlorophenyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]propanoic acid	Investigative	122192184	C21H21ClN2O2	368.9	C[C@@H]1CC2=C([C@H](N1CCC(=O)O)C3=CC=C(C=C3)Cl)NC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder
T22939	Progesterone receptor	BL2ZC1	(E)-3-[4-[(1R,3R)-3-Methyl-2-(2-methylpropyl)-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]phenyl]prop-2-enoic acid	Investigative	122192190	C25H28N2O2	388.5	C[C@@H]1CC2=C([C@H](N1CC(C)C)C3=CC=C(C=C3)/C=C/C(=O)O)NC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder
T22939	Progesterone receptor	BMJF21	(2E)-3-{4-[(1E)-1,2-Diphenylbut-1-enyl]phenyl}acrylic acid	Investigative	5288494	C25H22O2	354.4	CC/C(=C(\\C1=CC=CC=C1)/C2=CC=C(C=C2)/C=C/C(=O)O)/C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T22939	Progesterone receptor	BQ6C9Z	2-[(1R,3R)-1-(4-Chlorophenyl)-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-2-yl]ethanol	Investigative	122192183	C20H21ClN2O	340.8	C[C@@H]1CC2=C([C@H](N1CCO)C3=CC=C(C=C3)Cl)NC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder
T22939	Progesterone receptor	BRC9Q6	(E)-3-[4-[(1R,3R)-2-[(2S)-3-Hydroxy-2-methylpropyl]-3-methyl-1,3,4,9-tetrahydropyrido[3,4-b]indol-1-yl]phenyl]prop-2-enoic acid	Investigative	122192188	C25H28N2O3	404.5	C[C@@H]1CC2=C([C@H](N1C[C@H](C)CO)C3=CC=C(C=C3)/C=C/C(=O)O)NC4=CC=CC=C24	IC50 ~ 100000 nM	Poor binder