TTD_Target_ID Target_Name TTD_Drug_ID Drug_Name Drug_Highest_Status Drug_PubchemID Molecular_Formula Molecular_Weight Canonical_SMILES Activity Binder_Type T22977 Superoxide dismutase Cu-Zn B0NOR4 1,4-Bis[3-(imidazol-1-yl)propylamino]benzo[g]phthalazine Investigative 24823796 C24H26N8 426.5 C1=CC=C2C=C3C(=CC2=C1)C(=NN=C3NCCCN4C=CN=C4)NCCCN5C=CN=C5 IC50 = 67900 nM Poor binder T22977 Superoxide dismutase Cu-Zn B4NL0Z Chembl4129006 Investigative 145963675 C20H23FN2O2 342.4 COC1=CC=C(C=C1)C(=O)CCN2CCN(CC2)C3=CC=C(C=C3)F IC50 = 145800 nM Poor binder T22977 Superoxide dismutase Cu-Zn B7OIX5 1-[3-(Imidazol-1-yl)propylamino]-4-chlorobenzo[g]phthalazine Investigative 24823942 C18H16ClN5 337.8 C1=CC=C2C=C3C(=CC2=C1)C(=NN=C3Cl)NCCCN4C=CN=C4 IC50 = 129300 nM Poor binder T22977 Superoxide dismutase Cu-Zn B7PY2O Chembl4127450 Investigative 145961082 C20H23ClN2O2 358.9 COC1=CC=C(C=C1)C(=O)CCN2CCN(CC2)C3=CC=C(C=C3)Cl IC50 = 100000 nM Poor binder T22977 Superoxide dismutase Cu-Zn B8KU5G 1-N,4-N-Bis(3-imidazol-1-ylpropyl)phthalazine-1,4-diamine Investigative 71462627 C20H24N8 376.5 C1=CC=C2C(=C1)C(=NN=C2NCCCN3C=CN=C3)NCCCN4C=CN=C4 IC50 = 65980 nM Poor binder T22977 Superoxide dismutase Cu-Zn BBY16M Chembl4128846 Investigative 145960712 C20H23N3O4 369.4 COC1=CC=C(C=C1)C(=O)CCN2CCN(CC2)C3=CC=C(C=C3)[N+](=O)[O-] IC50 ~ 100000 nM Poor binder T22977 Superoxide dismutase Cu-Zn BJ7QL5 N-(Pyridin-2-ylmethyl)-2-(3,6,9,15-tetrazabicyclo[9.3.1]pentadeca-1(15),11,13-trien-6-yl)ethanamine;hydrochloride Investigative 71717652 C19H29ClN6 376.9 C1CN(CCNCC2=CC=CC(=N2)CN1)CCNCC3=CC=CC=N3.Cl IC50 = 178500 nM Poor binder T22977 Superoxide dismutase Cu-Zn BP46FY 13-Hydroxypodocarpa-8,11,13-triene-18-oic acid methyl ester Investigative 101519736 C18H24O3 288.4 C[C@]12CCC[C@@]([C@@H]1CCC3=C2C=CC(=C3)O)(C)C(=O)OC IC50 = 58900 nM Poor binder T22977 Superoxide dismutase Cu-Zn BP5D7W 1-N,4-N-Bis[2-(1H-imidazol-5-yl)ethyl]phthalazine-1,4-diamine Investigative 71460923 C18H20N8 348.4 C1=CC=C2C(=C1)C(=NN=C2NCCC3=CN=CN3)NCCC4=CN=CN4 IC50 = 125320 nM Poor binder T22977 Superoxide dismutase Cu-Zn BU5S2K 1,4-Bis(3'-Pyrazolylamino)Benzo[G]Phthalazine Investigative 51003102 C18H14N8 342.4 C1=CC=C2C=C3C(=CC2=C1)C(=NN=C3NC4=CC=NN4)NC5=CC=NN5 IC50 = 96600 nM Poor binder T22977 Superoxide dismutase Cu-Zn BUT3C5 Fortunin E Investigative 24970402 C20H28O4 332.4 CC(C)C1=C(C=C2C(=C1)C(=O)[C@@H]([C@@H]3[C@@]2(CCC[C@@]3(C)CO)C)O)O IC50 = 56600 nM Poor binder T22977 Superoxide dismutase Cu-Zn BW5HL2 4-Chloro-1-(3''-pyrazolylamino)benzo[g]phthalazine Investigative 51003103 C15H10ClN5 295.72 C1=CC=C2C=C3C(=CC2=C1)C(=NN=C3Cl)NC4=CC=NN4 IC50 = 103300 nM Poor binder T22977 Superoxide dismutase Cu-Zn BWM92N 4-Chloro-N-[2-(1H-imidazol-5-yl)ethyl]phthalazin-1-amine Investigative 71459115 C13H12ClN5 273.72 C1=CC=C2C(=C1)C(=NN=C2Cl)NCCC3=CN=CN3 IC50 = 71460 nM Poor binder T22977 Superoxide dismutase Cu-Zn BX06FM 4-Chloro-N-(3-imidazol-1-ylpropyl)phthalazin-1-amine Investigative 62140981 C14H14ClN5 287.75 C1=CC=C2C(=C1)C(=NN=C2Cl)NCCCN3C=CN=C3 IC50 = 83120 nM Poor binder