TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T24587	O-6-methylguanine-DNA-alkyltransferase	B64JOI	2-Butanone, 1-[(2-amino-9H-purin-6-yl)oxy]-	Investigative	10632766	C9H11N5O2	221.22	CCC(=O)COC1=NC(=NC2=C1NC=N2)N	IC50 = 93200 nM	Poor binder
T24587	O-6-methylguanine-DNA-alkyltransferase	B6LR7S	O6-Substituted Guanine Deriv. 19	Investigative	5329506	C14H13N5O	267.29	C=C(COC1=NC(=NC2=C1NC=N2)N)C3=CC=CC=C3	IC50 = 77000 nM	Poor binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BEH1Q7	6-Heptoxy-7H-purin-2-amine	Investigative	5329495	C12H19N5O	249.31	CCCCCCCOC1=NC(=NC2=C1NC=N2)N	IC50 ~ 100000 nM	Poor binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BF8WT6	1-[(2-Amino-7H-purin-6-yl)oxy]propan-2-one	Investigative	5329508	C8H9N5O2	207.19	CC(=O)COC1=NC(=NC2=C1NC=N2)N	IC50 = 95000 nM	Poor binder
T24587	O-6-methylguanine-DNA-alkyltransferase	BHZ58S	2,6-Diamino-4-benzyloxypyrimidine	Investigative	10130617	C11H12N4O	216.24	C1=CC=C(C=C1)COC2=NC(=NC(=C2)N)N	IC50 = 170000 nM	Poor binder