TTD_Target_ID	Target_Name	TTD_Drug_ID	Drug_Name	Drug_Highest_Status	Drug_PubchemID	Molecular_Formula	Molecular_Weight	Canonical_SMILES	Activity	Binder_Type
T24823	Lysine-specific histone demethylase 1B	D0H0HJ	Tranylcypromine	Approved	5530	C9H11N	133.19	C1C(C1N)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	B1L5ZS	Chembl4299285	Investigative	145949030	C101H171N37O29	2367.7	CC(C)C[C@H](C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CO)C(=O)N[C@H](CC(=O)O)C(=O)N2CCC[C@@H]2C(=O)N[C@H](CC(=O)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N3CCC[C@@H]3C(=O)N[C@@H](CC(=O)N)C(=O)N[C@H](CC4=CC=C(C=C4)O)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(=O)N)C(=O)N)NC(=O)[C@@H](CCCNN)NC(=O)[C@@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]5CCCN5	IC50 ~ 50000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	B47YIO	N-[4-[(1S,2R)-2-Aminocyclopropyl]phenyl]-4-morpholin-4-ylbenzamide;hydrochloride	Investigative	118536083	C20H24ClN3O2	373.9	C1COCCN1C2=CC=C(C=C2)C(=O)NC3=CC=C(C=C3)[C@@H]4C[C@H]4N.Cl	IC50 = 74700 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	B7V2FC	Chembl4162448	Investigative	145956132	C16H23ClN2	278.82	C1CC(CCC1N)N[C@@H]2[C@@H]3[C@H]2C4=CC=CC=C4C3.Cl	IC50 ~ 100000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	B7ZMX8	N-[4-[(1S,2R)-2-Aminocyclopropyl]phenyl]-4-(furan-3-yl)benzamide;hydrochloride	Investigative	127031655	C20H19ClN2O2	354.8	C1[C@H]([C@@H]1N)C2=CC=C(C=C2)NC(=O)C3=CC=C(C=C3)C4=COC=C4.Cl	IC50 = 51000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	B8S1LV	N-(3-(Methoxymethyl)phenyl)-4-methyl-4H-thieno[3,2-b]pyrrole-5-carboxamide	Investigative	51049245	C16H16N2O2S	300.4	CN1C2=C(C=C1C(=O)NC3=CC=CC(=C3)COC)SC=C2	IC50 ~ 100000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	B9D2YH	Chembl4166776	Investigative	145954281	C16H16ClN	257.76	C1[C@H]2[C@H]([C@@H]2N)C3=C1C=C(C=C3)C4=CC=CC=C4.Cl	IC50 ~ 100000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	BAO6K7	(1S,2R)-2-Phenylcyclopropan-1-amine;(1R,2S)-2-phenylcyclopropan-1-amine	Investigative	73417116	C18H22N2	266.4	C1[C@H]([C@@H]1N)C2=CC=CC=C2.C1[C@@H]([C@H]1N)C2=CC=CC=C2	IC50 ~ 100000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	BCP1S6	Chembl4174280	Investigative	145952331	C17H19ClN2O	302.8	COC1=C(C=CC=N1)CN[C@@H]2[C@@H]3[C@H]2C4=CC=CC=C4C3.Cl	IC50 ~ 100000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	BCS5P7	Iadademstat	Investigative	71543365	C15H22N2	230.35	C1CC(CCC1N)N[C@@H]2C[C@H]2C3=CC=CC=C3	IC50 ~ 100000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	BDB1F6	Chembl4299338	Investigative	145948690	C102H173N37O29	2381.7	CC(C)C[C@H](C(=O)N[C@H](C(C)C)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CO)C(=O)N[C@H](CC(=O)O)C(=O)N2CCC[C@@H]2C(=O)N[C@H](CC(=O)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N3CCC[C@@H]3C(=O)N[C@@H](CC(=O)N)C(=O)N[C@H](CC4=CC=C(C=C4)O)C(=O)N[C@H](CO)C(=O)N[C@H](CCC(=O)N)C(=O)N)NC(=O)[C@@H](CCCNNC)NC(=O)[C@@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H]5CCCN5	IC50 ~ 50000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	BF8Q9X	4-Methyl-N-[3-[[4-(1-methylpiperidin-4-yl)oxyphenoxy]methyl]phenyl]thieno[3,2-b]pyrrole-5-carboxamide	Investigative	118913669	C27H29N3O3S	475.6	CN1CCC(CC1)OC2=CC=C(C=C2)OCC3=CC(=CC=C3)NC(=O)C4=CC5=C(N4C)C=CS5	IC50 ~ 100000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	BJRA57	N-[4-[(1S,2R)-2-Aminocyclopropyl]phenyl]benzamide	Investigative	46236753	C16H16N2O	252.31	C1[C@H]([C@@H]1N)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3	IC50 = 58300 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	BKS7V9	Chembl4160042	Investigative	145959891	C16H23ClN2	278.82	C1CNCCC1CN[C@@H]2[C@@H]3[C@H]2C4=CC=CC=C4C3.Cl	IC50 ~ 100000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	BLR45X	N-[(2S)-1-(Benzylamino)-1-oxo-6-[(2-phenylcyclopropyl)amino]hexan-2-yl]benzamide	Investigative	76281715	C29H33N3O2	455.6	C1C(C1NCCCC[C@@H](C(=O)NCC2=CC=CC=C2)NC(=O)C3=CC=CC=C3)C4=CC=CC=C4	IC50 = 60000 nM	Poor binder
T24823	Lysine-specific histone demethylase 1B	BRJC12	4-Methyl-N-[3-[(4-piperidin-4-yloxyphenoxy)methyl]phenyl]thieno[3,2-b]pyrrole-5-carboxamide	Investigative	118913682	C26H27N3O3S	461.6	CN1C2=C(C=C1C(=O)NC3=CC=CC(=C3)COC4=CC=C(C=C4)OC5CCNCC5)SC=C2	IC50 ~ 100000 nM	Poor binder